CN1843395A - Antibacterial and inflammatory-diminishing tincture containing bee glue - Google Patents

Abstract

The invention relates to a Chinese medicinal preparation extracted from pollen and bee glue, which can be used for treating rhinitis, skin ulcer, tumor and polypus.

Description

Antibacterial and inflammatory-diminishing tincture containing bee glue

Antibacterial and inflammatory-diminishing tincture containing bee glue is in the nineteen ninety front and back of originating among the people, and the application time has reached 15 years.In secular application process, created the treatment case of a large amount of mysteries, have high medical value.Aspect the treatment difficult miscellaneous diseases, received significant curative effect especially.Over 15 years, treated a large amount of provincial large hospitals and failed the difficult diseases of effectively curing.My grandson suffered from gland sample body hypertrophic rhinitis in 2004, and after People's Hospital of Shanxi Prov., the big First Academy in mountain, 301 Hospital checked diagnosis, all thinking needed operative treatment, but after directly cure after using this medicine, had effectively avoided the damage of operation to human body.For this medicine can being served the patient better, thus decision application this patent, so that broad research, exploitation, application.

One, a kind of pure Chinese medicinal preparation that is formed by extractions such as pollen, propolis, the Radix Angelicae Dahuricae and Olibanums of technical field antibacterial and inflammatory-diminishing tincture containing bee glue is the translucent limpid liquid of a brown.This product oral administration and externally all can.Be mainly used in the inside and outside skin ulcer of treatment, inflammation, have stronger bactericidal antiphlogistic effect, aspect all types of rhinitis of treatment, effect is particularly remarkable especially.

The type of rhinitis mainly contains: type, sinusitis etc. such as chronic hypertrophic rhinitis, allergic rhinitis, chronic rhinitis, atrophic rhinitis, chronic rhinitis sicca, sinusitis

The method of treatment rhinitis mainly contains following several at present:

(1) application of vasoconstrictor nasal drop is limited to light-duty case.

(2) injection of sclerosing agent under the concha nasalis inferior mucosa after its mechanism of action is injection of sclerosing agent, can make the local chemical inflammatory reaction that takes place, and produces scar tissue, dwindles the concha nasalis volume, improves ventilation.50% Glucose Liquid commonly used adds 15% sodium chloride solution, 5% sodium morrhuate or 80% glycerol etc.After the concha nasalis topical anesthesia, thrust backward from concha nasalis inferior lower edge front end is parallel with 22～No. 23 elongated syringe needles, transfixation mucosa not, limit withdraw of the needle marginal not is penetrated sclerosing agent, till syringe needle is extracted.Also can divide 3 injections in concha nasalis inferior front end, middle part, rear end, every side injection 0.5ml, per 10 days 1 time is a course of treatment with 3～5 times.

(3) mucosal tissue of electric coagulation plumpness under the concha nasalis inferior mucosa makes to produce the cicatrix contraction.After topical anesthesia, the acusector head thrusts from the concha nasalis inferior front end, extracts after solidifying for 20～30 seconds, and electric current is 10～30 milliamperes.

(4) operative therapy: general treatment is invalid, or mucosa is significantly plump, or plump part is positioned at concha nasalis inferior rear end or lower edge, feasible partial inferior turbinectomy or partial middle turbinectomy.The concha nasalis inferior excision is too much unsuitable, is no more than 1/3 of concha nasalis inferior in principle, in order to avoid influence nasal mucosa function or secondary atrophic rhinitis.Bone hypertrophy person, the concha nasalis inferior of should going is sticking-the subperiosteum excision, both can improve the ventilation drain of nasal cavity, again without detriment to the physiological function of nasal mucosa.The parasympathetic nervous activity increases during nasal allergy, cuts off nasal cavity and melts the sympathetic nerve supply, can reduce its activity.This class operation comprises vidianneurectomy, anterior ethmoidal nerve amputation and superficial greater petrosal nerve amputation.Above-mentioned operation has all showed significant short term effect, but the late result report differs.

The parasympathetic nervous activity increases during nasal allergy, cuts off nasal cavity and melts the sympathetic nerve supply, can reduce its activity.This class operation comprises vidianneurectomy, anterior ethmoidal nerve amputation and superficial greater petrosal nerve amputation.Above-mentioned operation has all showed significant short term effect, but the late result report differs.

Nasal obstruction then can adopt freezing, laser, sealing, sclerosing agent than severe patient.

Can try controlling the nonresponder for a long time.Purpose is to make nasal cavity to dwindle, and reduces air imbibed quantity, to reduce water evaporates, reduces pus crusts and forms, and can stimulate nasal mucosa to make to be congested and secretion increases, and improves symptom.

Cryosurgery is that to place the concha nasalis inferior surface to do on special freezing head freezing, each 1～2 minute, the pathological changes mucosal necrosis is come off and regenerated mucosa.

(5) perennial allergic rhinitis's Drug therapy: antihistaminic, sodium cromoglicate, adrenocortical hormone and cholinolytic class medicine all can be used.But this type rhinitis has often based on a certain symptom, so should select or change medicine according to change of illness state.The effective medicine of a certain script if continue to take may not as previous effectively, plant medicine (pharmacological action can) and often can prove effective if can change other in good time.

(6) specific immunotherapy: specific immunotherapy claims hyposensitization again.According to the allergen check result, the immersion with the male allergenic substances of skin test from the low concentration start injection, increases dosage one by one and increase concentration again behind certain hour, subtracts quick purpose to reach specificity.

(7) treatment by Chinese herbs:, take Chinese medicines such as the Radix Angelicae Dahuricae, Herba Schizonepetae, Bulbus Lilii, the Radix Astragali, Caulis Spatholobi, Fructus Xanthii, Flos Magnoliae, Herba Asari, Herba Menthae, Os Draconis Powder, Borneolum Syntheticum by certain prescription.

Above-mentioned Therapeutic Method is concluded not outgoing call operative treatment and Drug therapy.Operative treatment cost costliness, and sequela is bigger.Drug therapy is divided into takes orally and two kinds of externals, medicine for oral administration, and the medicine arrival disease time is long, and medicine is bigger to the influence of other organs of health, and medicine is difficult to control to the side effect of other organs of human body.The topical drug disease of can going directly, but the sterilization of topical drug in the market, toxin expelling, detumescence ability and to the nutrition immune scarce capacity of skin are difficult to fundamentally treat rhinitis.

Two, technical background

(1) drug ingredient introduction

1, pollen

Bee pollen is the complicated concentrate that many materials with nutritive value and drug effect value are formed, its rich in proteins, carbohydrate, lipid, nucleic acid, mineral, vitamin and other active substance, aminoacid, antibiotics etc.According to one's analysis, kind surplus active enzyme reaches 80 in the bee pollen, amino acid content is 6-7 a times of amino acid content in beef, the egg; Nucleic acid content is Hepar Gallus domesticus, dried shrimps 5-10 a times; Vitamin content is considerably beyond many kinds of fresh fruits and vegetable, and constant and trace element are nearly more than 27 kinds.Wherein: protein 20%-25%, total amino acid content be more than 20%, You Lianjisuan ﹠amp; Nbspl%-2%, carbohydrate 40%-50%,, ﹠amp; Nbsp5%-10%; Contain abundant vitamin B and protein, contain abundant mineral, also have multiple nutrients materials such as abundant vitamin, trace element, enzyme, hormone, bioactive substance.Thereby enjoy the laudatory title of " full nutrition source ", " highly enriched miniature nutrition library ".

Bee pollen has medicine and health-care effect widely, has stronger antiinflammatory antiinflammatory effect; Function with stronger sterilization, antiinflammatory, nourishes rough skin.Has excellent curative at treatment prostatitis, hyperlipemia, endocrine regulation, enhancing body immunity.

2, propolis

The propolis resin that to be Apis gather from positions such as the tree bud of plant, barks mixes the secretions with bodies of gland such as Apis lingual gland, wax glands again, a kind of colloid substance that is transformed through Apis processing.

(1) main component of propolis

Propolis is the natural resin shape material that Apis collects from branch, eye and the exudate of plant.The kind of the chemical substance of finding in propolis has: honeybee mistake, resinae, face cream class, aromatic oil, fat-soluble oils, pollen and other Organic substance.Ratio between these materials is different according to the difference of the collection of propolis ground, acquisition time.Studies show that the source of the resinae material in the propolis has three kinds: the material of getting involved in the plant transudate that Apis is gathered, the secretions of Apis internal metabolism and the propolis forming process.

Because the composition of propolis is very complicated, it is difficult being broken down into single each constituent.Common way is with ethanol soluble extracting section to be come out, and this part is called as " propolis balsam class " rest parts is to be insoluble to the component of ethanol or to be called the waxiness component.

In the propolis sample, should detect vitamin(e) R, ﹠amp; , C, E and mineral element silver, hydrargyrum, magnesium.Ferrum, calcium, aluminum, vanadium and silicon etc.The new propolis of gathering contains 55% resin and balsam, 30% Cera Flava, 10% fragrant volatile oil, 5% foreign material such as pollen approximately.Propolis is formed also different because of worker honeybees foraging activity resin season, area and nectariferous plant kind, and common have polytypes such as firelight or sunlight tree type, willow type, a tree type, XIANGSHU type, pinaster type, mixed type.

Analyze through modern science (the 7's), from propolis, isolate the number of chemical composition, prove that the propolis composition is very complicated.Flavone compound, acid, alcohol, phenol, aldehyde, ester, ether and alkene, mushroom, base class chemical compound and several amino acids, fatty acid, enzyme, vitamin, trace element etc. are wherein arranged.Specifically talk one by one below.

Contain a certain amount of (5～10w) pollen in the propolis.The propolis composition varies in different localities also not for wondering that the composition of different propolis samples quite has difference.Chinese scholar was also done a lot of researchs.For example: (nineteen eighty-threes) such as Shang Tianmin, Xu Jingyao obtains 7 kinds of chemical compounds with the thin layer chromatography partition method from propolis, the polyploid (SS) that 5 ' 7 dihydroxyflavones (chrysin), 3 hydroxyls, 4 methoxyl group osmanthus silicic acid, 34 dimethoxy corticinic acids, H hexadecylic acid and sulfur are arranged also has two kinds of needle-like yellow crystals and yellow crystal powder.The king grasp and, Zhang Huijuan etc. (1988) is with silica gel column chromatography and the thin chromatograph chromatogram analysis method of rotation, from the propolis of Beijing, isolate 7 chemical compounds, they are 5.7H flavonols, 3.5.7 trihydroxyflavone (galangin), 5.7 dihydroxy, 2 methoxy flavones. the sour methanol of 23 (alkane), two (2 ethylhexyl) vinegar of phthalic acid, the two isobutyl vinegar of phthalic acid and two (the 2 ethyl Buckie) esters of decanedioic acid.

At present, the chemist from propolis the composition of isolation identification have: flavonoid, terpenes, quinones, esters, aldehydes, phenols, ethers, organic acid, also have a large amount of aminoacid, enzyme, vitamin B1, B2, B6, E, A, polysaccharide, and the material of physiology such as the necessary mineral element of biological existence and pharmacological activity.Especially contain a large amount of flavonoids, terpene compound is the key character of propolis.Also, given propolis extensive and magical effect just because of the complicated and unique composition of propolis.

The elite of propolis collection animals and plants has complicated chemical composition.Propolis includes 20 big classes kind of nutrition surplus in the of totally three hundred, and main functional component with health role is bioactive substances such as flavone compound, polyphenols, sterin terpene compound, Citrin, caffeic acid ester and enzyme.

Wherein flavone compound has kind more than 70, and flavone is one of needed by human nutrient, can not synthesize in the body, but to regulating physiological function, it is significant to improve the life movement quality.Flavonoid in the propolis, terpenoid substance have the function that promotes the synthetic liver glycogen of exogenous glucose, and the effect of remarkable blood sugar lowering is arranged; Propolis has the ability that promotes tissue regeneration; the islet cells that pathological changes takes place there are treatment, reparation and protective effect; the insulin secretion function that it is brought into normal play; various active enzyme and other active substance such as contained trypsin, lipase in the propolis; can help to recover the pancreas function; promote the islet cells tissue regeneration, improve the carbohydrate metabolism balance of diabetics.

Rutin, galangin, Quercetin, 5 in the propolis, 7-dihydroxy-3,4-dimethyl flavone and 5-hydroxyl-4, Flavonoid substances and Citrin energy vessel softeninges such as 7-dimethoxy flavanone, reduce the fragility of blood vessel, microcirculation improvement prevents sclerosis of blood vessels, three-hypers (hyperglycemia hyperlipidemia hypercholesterolemia) is had tangible reduction effect.Chrysin in the propolis, acacetin, galangin can increase the vigor of immunocyte; immune organ tissue injury there are reparation and protective effect; can prevent that the pancreatic cell number from reducing and thymosin alpha 1 active decline; regulate hepatocyte function; strengthen the phagocytic activity of macrophage, construct the immunoprotection system of anti-cell canceration.

(2) therapeutical effect

1. Zhen Gui natural wide spectrum antibiotics.

Contain abundant and unique flavonoid, terpenoid substance in the propolis, various bacteria, fungus, virus etc. are had significant inhibition and killing action.Can be used for treating the disease that pathogenic microorganisms such as beriberi, tinea unguium, eczema, various ulcer, periodontitis, laryngitis, rhinitis, gastritis, urinary system infection, flu, hemorrhoid, diarrhoea cause.Little, the instant effect of consumption does not produce drug resistance, does not destroy useful bacterium colony.

2. Zhen Gui immunostimulant.

Have the raising immunologic function, can significantly improve the resistance against diseases of health. to preventing cold, cancer, old and feeble and elimination senile plaque, pigmentation have good action.

3. have tangible blood fat reducing, blood sugar reducing function.

The antibiotic toxin expelling effect of propolis, reinforced immunological effect, the multiple complications that glycosuria is caused has excellent prevention and therapeutic effect.Long-term clinical research shows that it is significant to the diabetics good health and a long life to take propolis.Remarkable to hypertension, hyperlipidemia, diabetes effect.Be the essential good medicine of diabetes patient.

4. have significantly anticorrosion, antioxidation.

Taking propolis for a long time not only can activating cell, eliminate mottle, can also building body, radiant, the youth resident.

5. has the effect that promotes tissue regeneration.

The energy quick-acting haemostatic powder, the healing of accelerated in wounds. burn, scald, wound etc. there are the obvious treatment effect.

6. propolis also has antitumor action.

From propolis, isolated the natural materials (PRCA) that several can directly suppress, kill cancerous cell, made propolis excellent prevention and therapeutic effect be arranged tumor, polyp.Japan's cancerology meeting, beautiful river university etc. discover that use propolis after 3 months to 1 year continuously, multiple cancerous cell is inactivation all.

Scientific research shows that propolis can directly suppress to kill cancerous cell. tumor, polyp there are excellent prevention and therapeutic effect.

7. treatment of vascular systemic disease.

Flavonoid substances content in the propolis is abundant, has effects such as good blood circulation promoting and blood stasis dispelling, vessel softening, blood fat reducing, prevention platelet aggregation, microcirculation improvement.Sclerosis of blood vessels, infraction, thrombosis, hyperlipidemia etc. there are excellent prevention and therapeutic effect.

8. other functions.

Also have significantly safely, effects such as antiinflammatory, pain relieving, antipruritic, anesthesia, radioprotective.

Special propolis is made by natural material, and is without any side effects to human body, and expense is cheap, taking convenience, the diabetes patient takes everyday, to blood sugar lowering, blood fat reducing, prevent and treat various complication all will produce miraculous effects, its promotion and application will bring glad tidings to numerous diabeticss.

2, the Radix Angelicae Dahuricae

(1) phytomorph

Perennial herb.The carefully vertical rib of stem tool, hollow, the close living pubescence in nearly inflorescence place.The leaf alternate, 2～3 times pinnation of bottom leaf, whole sliver is avette, and the top is sharp-pointed to long avette, and base portion is downward, the heavy sawtooth that the close life in edge is sharp-pointed, only hairiness on the arteries and veins; Long 3～the 6cm of petiole, base portion is expanded into sheath; Upper leaf is simplified to sheath.Universal umbel, 0～2 of involucre, sheath shape; Involucel sheet majority, lanceolar; Petal 5, yellow green, ovum shape lanceolar, top introversion; Stamen 5; Ovary is the next.Diachenium ellipse or subcircular, flat, schizocarp tool 5 ribs, side 4 ribs become aliform.5～June of florescence, really July phase.Be born in aquiprata, bushes, in the other sandy soil in river or the stone calculous soil.Main product Zhejiang, Sichuan.

(2) gather and process

Excavate between summer, autumn, decontamination is cleaned, and mixes Calx, place a week after, take out, dry.

(3) character

It is conical that root is, long 10～20cm, diameter 2～2.5cm.The surface taupe brown has the hole skin of transverse projections, and there is the stem trace of depression on the top.Matter is hard, section white, mealiness foot, skin zone's brown oil drop that gathers.Gas fragrance, acrid in the mouth, little hardship.

(4) the oval and circular section of decoction pieces, diameter 1.5-2.5cm, thick 2-3mm, cambium ring, xylem slightly is square, and xylem accounts for 1/2 of section.

(5) meridian distribution of property and flavor suffering, temperature.Attach to the lung and stomach meridians.

(6) the effect diffusing wind that induces sweat is sensible, pain relieving, dampness leukorrhagia stopping, detumescence and apocenosis.

(7) therapeutical effect

1. be used for affection of exogenous wind-cold, headache, nasal obstruction.The hot temperature of this product is delivered diffusing wind, awakening consciousness, and the same usefulness of medicine such as Chang Peiwu Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii are as Notoptreygium Decoction of Nine Ingredients.

2. be used for YANG MING headache, toothache, nasal sinusitis, rheumatic arthralgia.This product is hot diffusing and dry, You Yishan loose Yangming Channel rheumatism heresy and end neck pain and be good at, and reach on the fragrance, be apt to clearing the nasal passage.The treatment YANG MING headache, supraorbital bone pain, wind syndrome of head waits disease bitterly, and genus affection of exogenous wind-cold person can singly use, i.e. beam balls all; Or with the same usefulness of medicine such as Herba Schizonepetae, Radix Saposhnikoviae, Rhizoma Chuanxiong, as Chuanxiong Chatiao San; The person that belongs to the affection due to external wind and heat, but compatibility Herba Menthae, Flos Chrysanthemi, Fructus Viticis are equal to usefulness.The treatment toothache belongs to air-cooled person's compatibility Herba Asari; Belong to wind-fire person compatibility Gypsum Fibrosum, Rhizoma Coptidis.Control nasosinusitis headache, the time flow turbid tears, every and Fructus Xanthii, Flos Magnoliae, Herba Menthae are equal to usefulness, as Fructus Xanthii powder.Anemofrigid-damp arthralgia, lumbar and back pain, normal and Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Clematidis are used together.

3. leukorrhagia is too much.This product is kind removes the Yangming Channel damp and the dampness leukorrhagia stopping.Belong to the cold-damp leukorrhagia, can with the same usefulness of medicine such as Cornu Cervi Degelatinatum, Rhizoma Zingiberis Preparatum, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Os Draconis, as BAIDAI WAN; Belong to damp-heat vaginal discharge, then need compatibility Semen Plantaginis, Cortex Phellodendri to be equal to usefulness.

4. be used for sore and toxic.This product energy detumescence and apocenosis, pain relieving.Treatment carbuncle is from the beginning of, red and swollen heat pain, and medicine adapteds such as every and Flos Lonicerae, Radix Angelicae Sinensis, Squama Manis are as Xian fang Huoming Yin; Be equal to usefulness with Fructus Trichosanthis, Bulbus Fritillariae Uninbracteatae, Herba Taraxaci, control acute mastitis again and swell and ache.

In addition, still available skin rheumatism pruritus and the venom controlled of this product.

(8) usage and dosage decoction, 3～10g.Suitable amount used externally.

(9) use attention deficiency of YIN heat in blood person to avoid clothes.

(10) chemical constituent contains isoimperatorin (isoimperatorin), imperatorin (imperatorin), bergapton (bergapten), phellopterin (phellopterin), oxypeucedanin (oxypeucedanin) etc.

4, Olibanum

(1) source is the resin that oozes out of Burseraceae dungarunga Boswellia carterii Birdw and congener skin zone thereof.

(2) Olibanum: the irregular block sheet, often be mamillary, teardrop shaped sticks into agglomerate sometimes, and is faint yellow, and little sometimes band light green or brownish red are translucent, the mattness that has, and often have one deck off-white color dust.The matter heavily fortified point is crisp, the cured sample of section, tarnish, feeble QI fragrance, mildly bitter flavor.When chewing, soften into the blob of viscose sample and adhere to tooth, saliva becomes milky and little fragrant peppery sense is arranged.

(3) Olibanum (processed with vinegar): claim Olibanum (processed), surperficial pitchy, coarse, the smell of vinegar is arranged.Decoction pieces also has Olibanum (parched).

(4) meridian distribution of property and flavor suffering, hardship, temperature.GUIXIN, liver, spleen channel.

(5) effect is used

1. be used for affection of exogenous wind-cold, headache, nasal obstruction.The hot temperature of this product is delivered diffusing wind, awakening consciousness,

2. promoting blood circulation and stopping pain: can control all pains of blood stasis.

A. the blood system stasis of blood stagnates, all pains of trusted subordinate.

B. women's blood stasis, amenorrhea, dysmenorrhea ， mass in the abdomen.

C. rheumatism arthromyodynia, arthrodynia of extremities; The wound congestive edema is had a pain.

3. detumescence and promoting granulation: can be used for skin infection from the beginning of, red and swollen heat pain; Or the skin infection diabrosis, do not close up for a long time; And scrofula, the hard person that do not disappear of sucutaneous nodule.

4. be used for sore and toxic.This product energy detumescence and apocenosis, pain relieving.Treatment carbuncle is from the beginning of, red and swollen heat pain.

(6) consumption usage 3-10g.Suitable amount used externally.

(7) chemical constituent pine alkene, two Oleum Pini card, phellandrene, lauro lene, olibanol, Colophonium class

(8) use attention this product bitter in the mouth, go into decoct soup muddiness, the many clothes of stomach weak person easily cause vomiting, so consumption is too much unsuitable, stomach is weak especially should careful usefulness.The anemia of pregnant woman should not make

(2) main therapeutical effect

1. promoting blood circulation and stopping pain.This product energy detumescence and apocenosis, pain relieving can be controlled all pains of blood stasis.But detumescence and promoting granulation is used for skin infection from the beginning of, red and swollen heat pain; Or the skin infection diabrosis, do not close up for a long time; And scrofula, the hard person that do not disappear of sucutaneous nodule.

2. be used for YANG MING headache, toothache, nasal sinusitis, rheumatic arthralgia.This product is hot diffusing and dry, You Yishan loose Yangming Channel rheumatism heresy and end neck pain and be good at, and reach on the fragrance, be apt to clearing the nasal passage.The treatment YANG MING headache, supraorbital bone pain, wind syndrome of head waits disease bitterly, and genus affection of exogenous wind-cold person can singly use, i.e. beam balls all.

3, promote tissue repair:

Can promote ulcer healing, shorten 1/3～2/3 course of disease, especially to diabetic wounds do not heal, oral ulcer, gastric ulcer, duodenal ulcer, decubital ulcer, burn effect be remarkable.

4, to by antibacterial, virus, the caused various infection class diseases of fungus, as: inflammation such as tuberculosis, gastritis, beriberi, dermatosis are all effective.

5, have the raising immunologic function, can significantly improve the resistance against diseases of health.To preventing cold, cancer, old and feeble and elimination senile plaque, pigmentation have good action.

Contain abundant and unique flavonoid, terpenoid substance in this product, various bacteria, fungus, virus etc. are had significant inhibition and killing action.Can be used for treating the disease that pathogenic microorganisms such as beriberi, tinea unguium, eczema, various ulcer, periodontitis, laryngitis, rhinitis, gastritis, urinary system infection, flu, hemorrhoid, diarrhoea cause.

6, have significantly anticorrosion, antioxidation.

Can reduce by the third paddy transaminase, separate the liver poison, the protection hepatocyte, hepatitis B, liver cirrhosis, hepatitis C are had the excellent treatment effect, taking for a long time not only can activating cell, eliminate mottle, can also building body, radiant, the youth resident.In addition, can also strengthen the effects such as content of triglyceride in myocardial contraction, blood vessel dilating, the reduction blood, very obvious for prevention and treatment hypertension, heart disease, atherosclerotic effect.

7, the PRCA factor that contains in this product can directly suppress to kill cancerous cell.Tumor, polyp there are excellent prevention and therapeutic effect.

8, effectively treat all types of rhinitis, sinusitis, nasal polyp etc.

Three, summary of the invention

(1) technical issues that need to address

1, not according to the requirement of examining of new medicine, carries out pharmacology, the toxicological study of medicine.Though this medicine in application among the people for many years, and therapeutic effect is very outstanding.But because technical conditions limit, do not study always, do not have and will in addition analysis and summary of the perceptual knowledge of medicine still not risen to the height of reasonable cognition by the technical program of national regulation.

2, not according to the requirement of examining of new medicine, strict organizing and implementing clinical experiment.Though this medicine has been cured a large amount of patients among the people, because the inventor lacks the theoretical knowledge of drug control, so do not finish and write clinical experimental data by the pharmaceutical production requirement.

3, the GMP quality certification system by pharmaceutical production.This pharmaceutical production technology is comparatively simple, but batch production process and arts demand are by the GMP quality certification system.

(2) solve the technical scheme that its technical problem is taked

The exploitation of this medicine intends entrusting special pharmaceutical research mechanism to carry out the pharmacological toxicology research of standard, reaches national new drug and declares the requirement of examining.Entrust relevant medical institutions,, finish the clinical experiment report according to the clinical experiment requirement of national regulation.According to the requirement of national drug manufacturing enterprise, the plant and equipment of organizational building pharmaceutical production reaches and the GMP quality certification system by pharmaceutical production.

(3) beneficial effect

This medicine has extremely strong sterilization, toxin expelling, detumescence ability and to the nutrition immune ability of skin.Its distinguishing feature mainly contains:

1, this medicine mainly enters nasal sinuses and nasal cavity inside by the mode of spraying, drip, filling in, and the disease of can going directly greatly reduces influence and the side effect of medicine to its hetero-organization of human body.

2, has the dense effect of extremely strong row.Can get rid of nasal mucus and secretions thereof rapidly, help keeping nasal cavity totally unobstructed.Can get rid of toxin and secretions thereof in the inside and outside ulcer.

3, has very high sterilizing ability.Can effectively kill pathogenic microorganisms such as eczema, various ulcer, periodontitis, laryngitis, rhinitis, gastritis, urinary system infection, flu, hemorrhoid, diarrhoea.

4, can directly suppress to kill cancerous cell, tumor, polyp are had excellent prevention and therapeutic effect.

5, promote tissue repair:

Can promote ulcer healing, shorten 1/3～2/3 course of disease, especially to diabetic wounds do not heal, oral ulcer, gastric ulcer, duodenal ulcer, decubital ulcer, burn effect be remarkable.

Four, the specific embodiment

The organizing and implementing of this pharmaceutical production can be produced by investment institution's tissue of relevant pharmaceutical production by the mode of patent transfer, also can organize the production and selling of medicine by applicant oneself investment.

Claims (2)

1. the technical characterictic of antibacterial and inflammatory-diminishing tincture containing bee glue

A kind of pure Chinese medicinal preparation that is formed by pollen, propolis, the Radix Angelicae Dahuricae and Olibanum extraction of antibacterial and inflammatory-diminishing tincture containing bee glue is the translucent limpid liquid of a brown.This product oral administration and externally all can.This prescription is in the nineteen ninety front and back of originating among the people, and the application time has reached 15 years.In secular application process, created the treatment case of a large amount of mysteries, have high medical value.Aspect treatment inflammation class difficult miscellaneous diseases, received significant curative effect especially.Over 15 years, treated a large amount of provincial large hospitals and failed the difficult diseases of effectively curing.For this medicine being served the patient better, apply for this patent hereby, so that develop better, promote, use.Main therapeutical effect:

1) promoting blood circulation and stopping pain: this product energy detumescence and apocenosis, pain relieving, can control all pains of blood stasis.But detumescence and promoting granulation is used for skin infection from the beginning of, red and swollen heat pain; Or the skin infection diabrosis, do not close up for a long time; And scrofula, the hard person that do not disappear of sucutaneous nodule.

2) be used for YANG MING headache, toothache, nasal sinusitis, rheumatic arthralgia.This product is hot diffusing and dry, You Yishan loose Yangming Channel rheumatism heresy and end neck pain and be good at, and reach on the fragrance, be apt to clearing the nasal passage.The treatment YANG MING headache, supraorbital bone pain, wind syndrome of head waits disease bitterly.

3) promote tissue repair

Can promote ulcer healing, shorten 1/3～2/3 course of disease, especially to diabetic wounds do not heal, oral ulcer, gastric ulcer, duodenal ulcer, decubital ulcer, burn effect be remarkable.

4) to by antibacterial, virus, the caused various infection class diseases of fungus, as: inflammation such as tuberculosis, gastritis, beriberi, dermatosis are effective.

5) have the raising immunologic function, can significantly improve the resistance against diseases of health.To preventing cold, cancer, old and feeble and elimination senile plaque, pigmentation have good action.

Contain abundant and unique flavonoid, terpenoid substance in this product, various bacteria, fungus, virus etc. are had significant inhibition and killing action.Can be used for treating the disease that pathogenic microorganisms such as beriberi, tinea unguium, eczema, various ulcer, periodontitis, laryngitis, rhinitis, gastritis, urinary system infection, flu, hemorrhoid, diarrhoea cause.

6) have significantly anticorrosion, antioxidation.

Can reduce by the third paddy transaminase, separate the liver poison, the protection hepatocyte, hepatitis B, liver cirrhosis, hepatitis C are had the excellent treatment effect, taking for a long time not only can activating cell, eliminate mottle, can also building body, radiant, the youth resident.In addition, can also strengthen the effects such as content of triglyceride in myocardial contraction, blood vessel dilating, the reduction blood, very obvious for prevention and treatment hypertension, heart disease, atherosclerotic effect.

7) the PRCA factor that contains in this product can directly suppress to kill cancerous cell.Tumor, polyp there are excellent prevention and therapeutic effect.

8) effectively treat all types of rhinitis, sinusitis, nasal polyp etc.

2. ask the scope of patent protection

1) preceding continuous part

(1) " propolis, the Radix Angelicae Dahuricae, Olibanum " is used to develop anti-inflammatory type medicine and rhinitis quasi drugs simultaneously.

(2) propolis is used to develop all kinds of rhinitis quasi drugss.

2) characteristic

(1) medicine directly can be sprayed, permeates or spread upon disease and near position thereof, improve the therapeutic efficiency and the effect of medicine greatly, help dropping to minimum to the influence at other positions of health medicine.

(2) this medicine have sterilization, antiinflammatory, pain relieving, row dense, eliminate functions such as tumor, retraction body of gland, nutrition human body, repair tissue, help fundamentally curing all kinds of inflammation.

(3) this product designs for liquid, and science has been extracted the effective ingredient in the medicine, has rejected invalid components, has significantly reduced the toxic and side effects of medicine.In addition, the medicine of liquid condition helps effective absorption of human body, has improved the treatment speed and the effect of medicine greatly.