CN110833615A - A Chinese medicinal composition for treating chronic rhinitis by umbilical therapy, and its preparation method - Google Patents

A Chinese medicinal composition for treating chronic rhinitis by umbilical therapy, and its preparation method Download PDF

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CN110833615A
CN110833615A CN201911319985.3A CN201911319985A CN110833615A CN 110833615 A CN110833615 A CN 110833615A CN 201911319985 A CN201911319985 A CN 201911319985A CN 110833615 A CN110833615 A CN 110833615A
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traditional chinese
chinese medicine
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chronic rhinitis
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张�杰
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Shenzhen Dongfang Shengdian Traditional Chinese Medicine Health And Beauty Co Ltd
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Shenzhen Dongfang Shengdian Traditional Chinese Medicine Health And Beauty Co Ltd
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
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Abstract

The invention discloses a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy, which comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk. The invention also discloses a preparation process of the traditional Chinese medicine composition for treating chronic rhinitis by using the navel therapy. The medicament of the invention is powder which can be directly used for umbilical administration, is convenient for clinical application, convenient for carrying and low in cost, has the effects of dispelling wind and cold, freeing lung and dredging orifices, can effectively improve the clinical symptoms of nasal obstruction, dyspnea, sneeze, watery nasal discharge, headache, dizziness and the like of chronic rhinitis patients, has obvious clinical treatment effect and lasting curative effect, and has the total effective rate of more than 90 percent through comparison and observation of clinical treatment effect.

Description

A Chinese medicinal composition for treating chronic rhinitis by umbilical therapy, and its preparation method
Technical Field
The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy and a preparation process thereof.
Background
Along with the change of living conditions and living environment of people, the prevalence of electric fans and air conditioners in chronic rhinitis tends to increase year by year. Rhinitis is a chronic disease of nasal mucosa and submucosa chronic congestion and swelling, turbinate hypertrophy of turbinates, filamentous secretion discharge in nasal passages, nasal obstruction, sticky nasal discharge, sneeze, heavy nasal sound and headache. Clinically, most chronic rhinitis patients are allergic to common airborne allergens (mites, pollen, pets, molds and the like), certain foods (nuts, milk, peanuts, seafood and the like) and medicines. The disease course is long and lingering, and the disease is not easy to be cured completely in clinic, thereby seriously affecting the life quality of people.
At present, for chronic rhinitis patients, the main treatment mode of western medicine is symptomatic treatment, hormone medicine treatment is most commonly used in the western medicine treatment means, the treatment aims to mainly inhibit inflammatory reaction of nasal mucosa and reduce nasal hyperreactivity, diseases cannot be eradicated fundamentally, clinical symptoms can be improved, and toxic and side effects are easily caused to the patients by long-term application of the hormone medicine.
Rhinitis is a chronic disease of nasal mucosa and submucosa chronic congestion and swelling, turbinate hypertrophy of turbinates, filamentous secretion discharge in nasal passages, nasal obstruction, sticky nasal discharge, sneeze, heavy nasal sound and headache. The chronic rhinitis belongs to the category of allergic rhinitis in the traditional Chinese medicine, and common reasons comprise cold attacking lung, cold evil lodging lung, deficiency and cold of lung qi and lung qi obstruction. It is often seen in the elderly, women, children, and people with common cold. Clinically, western medicine hormone treatment usually takes effect at that time, and after the treatment is stopped, nasal obstruction, rhinorrhea and sneezing appear, and symptoms are repeated; the traditional Chinese medicine preparation has better effect on treating rhinitis, but needs to be taken for a long time, so that a patient can not insist on the rhinitis for a long time and has certain side effect. The traditional Chinese medicine navel therapy is a traditional natural therapy, has the advantages of remarkable curative effect, quick response, safety, reliability, few side effects and the like, and has unique characteristics in clinical application. The main causes are lung qi deficiency, weak defensive exterior, wind-cold attacking the nasal orifice due to deficiency, the pathogenic factors fighting positively, lung qi failing to regulate, body fluid stopping and accumulating, nasal orifice obstruction, sneezing and snivel due to the cold, spleen qi failing to distribute to the lung due to spleen deficiency, lung qi failing to be rooted in the kidney, kidney deficiency failing to control and take up, qi failing to return to original qi, wind evil invading the interior. Therefore, allergic rhinitis is diseased in the lung, but its pathological changes have a certain relationship with the spleen and kidney. In clinical manifestations, the physician needs to relieve nasal obstruction, strengthen healthy qi to eliminate pathogens, tonify lung qi and strengthen the exterior, with the syndrome of deficiency and excess complicated with each other.
In clinical reports of treating chronic rhinitis by using Chinese patent medicines, the Chinese patent medicines show that the treatment course is short, the effect is quick, the curative effect is safe and reliable, and the Chinese patent medicines have the effect of treating both principal and secondary aspects of disease. However, most of the existing Chinese patent medicines are decoction during treatment and the components of the prescription are complex, so the traditional Chinese patent medicines are not convenient for patients in clinical use, and the volatilization of effective components caused by improper decoction methods during decoction often causes the reduction of drug effect.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for treating chronic rhinitis by using navel therapy and a preparation process thereof, and aims to solve the problems in the background art.
In order to achieve the purpose, the invention provides the following technical scheme: a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy is characterized in that: the paint comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
The composition preferably comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
Preferably, the Chinese medicinal composition is powder.
Preferably, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: sun drying radix Angelicae Dahuricae, flos Magnoliae, fructus Xanthii, herba Schizonepetae, radix Saposhnikoviae, rhizoma Zingiberis recens, herba Menthae, flos Chrysanthemi and Bulbus Allii Fistulosi respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Compared with the prior art, the medicament is powder, can be directly applied to umbilical region administration, is convenient for clinical application, convenient to carry and low in cost, has the effects of dispelling wind and cold, dispersing lung qi and dredging orifices, can effectively improve the clinical symptoms of nasal obstruction, dyspnea, sneeze, watery nasal discharge, headache, dizziness and the like of chronic rhinitis patients, has obvious clinical treatment effect and lasting curative effect, and has the total effective rate of over 90 percent through comparison and observation of the clinical treatment effect.
Detailed Description
The invention is further illustrated by the following examples, without limiting the scope of the invention.
Example 1
The invention provides a technical scheme, and a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
In the embodiment, the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
In the embodiment, the traditional Chinese medicine composition is powder.
In the embodiment, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: drying radix Angelicae Dahuricae 150g, flos Magnoliae 150g, fructus Xanthii 150g, herba Schizonepetae 90g, radix Saposhnikoviae 90g, rhizoma Zingiberis recens 30g, herba Menthae 90g, flos Chrysanthemi 90g, and Bulbus Allii Fistulosi 30g in the sun respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Example 2
The invention provides a technical scheme, and a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
In the embodiment, the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
In the embodiment, the traditional Chinese medicine composition is powder.
In the embodiment, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: drying radix Angelicae Dahuricae 150g, flos Magnoliae 150g, fructus Xanthii 150g, herba Schizonepetae 90g, radix Saposhnikoviae 90g, rhizoma Zingiberis recens 90g, herba Menthae 90g, flos Chrysanthemi 90g, and Bulbus Allii Fistulosi 90g in the sun respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Example 3
The invention provides a technical scheme, and a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
In the embodiment, the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
In the embodiment, the traditional Chinese medicine composition is powder.
In the embodiment, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: drying radix Angelicae Dahuricae 150g, flos Magnoliae 150g, fructus Xanthii 150g, herba Schizonepetae 270g, radix Saposhnikoviae 270g, rhizoma Zingiberis recens 30g, herba Menthae 270g, flos Chrysanthemi 270g, and Bulbus Allii Fistulosi 30g in the sun respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Example 4
The invention provides a technical scheme, and a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
In the embodiment, the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
In the embodiment, the traditional Chinese medicine composition is powder.
In the embodiment, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: drying radix Angelicae Dahuricae 150g, flos Magnoliae 150g, fructus Xanthii 150g, herba Schizonepetae 270g, radix Saposhnikoviae 270g, rhizoma Zingiberis recens 90g, herba Menthae 270g, flos Chrysanthemi 270g, and Bulbus Allii Fistulosi 90g in the sun respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Example 5
The invention provides a technical scheme, and a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
In the embodiment, the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
In the embodiment, the traditional Chinese medicine composition is powder.
In the embodiment, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: drying radix Angelicae Dahuricae 450g, flos Magnoliae 450g, fructus Xanthii 450g, herba Schizonepetae 90g, radix Saposhnikoviae 90g, rhizoma Zingiberis recens 30g, herba Menthae 90g, flos Chrysanthemi 90g, and Bulbus Allii Fistulosi 30g in the sun respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Example 6
The invention provides a technical scheme, and a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
In the embodiment, the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
In the embodiment, the traditional Chinese medicine composition is powder.
In the embodiment, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: drying radix Angelicae Dahuricae 450g, flos Magnoliae 450g, fructus Xanthii 450g, herba Schizonepetae 90g, radix Saposhnikoviae 90g, rhizoma Zingiberis recens 90g, herba Menthae 90g, flos Chrysanthemi 90g, and Bulbus Allii Fistulosi 90g in the sun respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Example 7
The invention provides a technical scheme, and a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
In the embodiment, the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
In the embodiment, the traditional Chinese medicine composition is powder.
In the embodiment, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: drying radix Angelicae Dahuricae 450g, flos Magnoliae 450g, fructus Xanthii 450g, herba Schizonepetae 270g, radix Saposhnikoviae 270g, rhizoma Zingiberis recens 30g, herba Menthae 270g, flos Chrysanthemi 270g, and Bulbus Allii Fistulosi 30g in the sun respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Example 8
The invention provides a technical scheme, and a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
In the embodiment, the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
In the embodiment, the traditional Chinese medicine composition is powder.
In the embodiment, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: drying radix Angelicae Dahuricae 450g, flos Magnoliae 450g, fructus Xanthii 450g, herba Schizonepetae 270g, radix Saposhnikoviae 270g, rhizoma Zingiberis recens 90g, herba Menthae 270g, flos Chrysanthemi 270g, and Bulbus Allii Fistulosi 90g in the sun respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Examples of the experiments
The drugs prepared in the above examples 1 to 8 were tested with the cocklebur fruit drop pills for treating rhinitis (manufactured by Sichuan Herun pharmaceutical Co., Ltd.) in an efficient manner, and the results are shown in Table 1. In order to show the treatment effect of the medicine on chronic rhinitis, 100 chronic rhinitis patients are selected in total and observed in clinical treatment effect, and the age is 21-67 years old. The groups were randomly divided into 9 groups. Of these, 8 groups were the example group, and one group was the control group. The medicine is applied to the embodiment group, 1-3g of proper amount of powder is taken each time, the powder is blended into a soft paste by boiling water, the soft paste is filled on the umbilical region of a patient, moxibustion is carried out by a moxa column, 1 time is taken every day, the time is 60min-120min each time, and the medicine is fixed on the umbilical region for 6-8 hours by an adhesive tape after the moxibustion is finished; fructus Xanthii dripping pill (produced by Sichuan Herun pharmaceutical Co., Ltd.) for treating rhinitis in control group has 28 pills each time, and 3 times a day. Each group took 2 weeks as a course of treatment.
The clinical curative effect standard of the chronic rhinitis is as follows:
the effect is shown: the main symptoms of nasal obstruction, rhinorrhea, dyspnea and sneeze are slightly better, the symptoms recover more than 30% before treatment, and headache and dizziness are obviously changed;
the method has the following advantages: the main symptoms of nasal obstruction, rhinorrhea, dyspnea, sneeze and the like recover more than 60 percent than before treatment, and the headache disappears;
improvement: nasal obstruction, rhinorrhea, dyspnea, sneeze, headache and dizziness disappear;
and (4) invalidation: the patient had no significant reduction or worsening of the underlying symptoms.
The total effective rate is (significant effect + effective + improvement)/the total number of people is multiplied by 100%.
TABLE 1 comparison of clinical treatment effects of examples 1-8 and fructus Xanthii dripping pill for treating rhinitis
Figure BDA0002326874650000091
The total efficiency of the invention is: (285+131+351)/800 × 100 ═ 95.875%.
The angelica dahurica in the medicine has pungent and slightly bitter taste, warm nature and fragrant smell, governs hand-foot yangming, ascends the head and face, and has the effects of relieving exterior syndrome and dispelling cold, dispelling wind and relieving pain, dredging nasal orifices, eliminating dampness and stopping leukorrhagia, reducing swelling and expelling pus, and dispelling wind and relieving itching. Flos Magnoliae is pungent in flavor and warm in nature, and has the functions of expelling wind and cold, dredging the orifice, warming and dredging the channels, ascending clear and improving eyesight, and dispelling wind and heat, and can help clear yang and ascend the head and brain. The cocklebur fruit is pungent and bitter in taste and warm in nature, has the effects of dispelling wind-cold, freeing nasal orifices, eliminating dampness and relieving pain, and has the effects of freeing the brain top and externally reaching the skin, and the three medicines are monarch medicines together and have the effects of dispelling wind and cold, freeing lung and freeing orifices and relieving pain. Schizonepeta, herba Schizonepetae is pungent, slightly bitter, slightly warm in nature, and has the effects of dispelling pathogenic wind and relieving exterior syndrome; promoting eruption; the action of stopping bleeding. Fang Feng is pungent and sweet in flavor and warm in nature. Has effects in relieving exterior syndrome, inducing perspiration, dispelling pathogenic wind, and removing dampness. The ginger is pungent in flavor and slightly warm in nature, has the functions of sweating and relieving exterior syndrome, warming middle energizer and arresting vomiting, warming lung and relieving cough, and relieving fish and crab toxicity and drug toxicity, and is used as a ministerial drug for enhancing the functions of expelling wind and removing cold, ventilating lung and relieving exterior syndrome and easing nasal obstruction. The mint is cool in nature and pungent in taste, has the functions of clearing lung and soothing liver, and clearing heat and promoting eyesight, and the chrysanthemum is sweet and bitter in taste and slightly cold in nature, and has the effects of dispelling wind and heat, calming liver yang, clearing liver and improving eyesight, and clearing heat and removing toxicity. The two herbs are used together as adjuvant drugs to clear bitter and cold and descend to harmonize the actions of the drugs and inhibit the dryness of the drugs. The scallion stalk is pungent in flavor and warm in nature, has the functions of invigorating yang and promoting qi circulation, and is used as a guiding drug for ascending and descending the clear and turbid, dispersing wind-cold and relieving lung orifice pain with brain fluid self-consolidating .
Modern pharmacological research shows that the angelica has the effects of relieving fever, easing pain, resisting inflammation and exciting the center, and the angelica toxin can excite the brain-extending respiratory center, the blood vessel movement center, the vagal center and the spinal cord in a small amount to excite the respiration: 15g (crude drug)/kg of angelica dahurica decoction is used for intragastric administration, the heat clearing effect is obvious on the rabbits with fever caused by subcutaneous injection of peptone on the back, the effect is superior to 0.1g/kg of aspirin, the inhibition rates of the acetic acid writhing reaction of mice are 69.6%, 52.86% and 40.53% respectively when the angelica dahurica decoction, the ether extract and the water extract are used for intragastric administration, and the inhibition rates of the acetic acid writhing reaction of the mice are respectively 69.6%; the compound preparation has an obvious inhibiting effect on ear inflammation of mice with xylene, can improve the in-vivo hypersensitive state of allergic disease patients, improves microcirculation by enhancing the immunity of organisms, and has the effects of relieving fever, easing pain and resisting inflammation; flos Magnoliae has inhibitory effect on various pathogenic fungi, and 15-30% flos Magnoliae decoction or infusion has local anesthetic effect on animals (infiltration anesthesia on guinea pig and interdiction anesthesia on frog). The Japanese magnolia flower M.kobus has obvious antiviral effect on the gonococcal choriomeningitis virus in vitro and in vivo (the mice are injected with the decoction subcutaneously). Fructus Xanthii has antiinflammatory effect, and diterpene hydroxy acid atractyloside contained in the product has antiinflammatory effect as shown by rat carrageenin edema test. The LD50 for intraperitoneal injection, subcutaneous injection and oral administration is 2.9, 5.3 and 350mg/kg respectively. The cocklebur fruit decoction has certain bacteriostasis to staphylococcus aureus in vitro, and the acetone or ethanol extract thereof also has bacteriostasis to trichophyton rubrum in vitro. Fructus Xanthii 100% decoction 0.3 ml/mouse has effect of relieving cough; 15ml/kg has no phlegm eliminating effect on rabbit, and the tincture has breath exciting effect on frog. The schizonepeta has the effects of relieving fever and easing pain: the typhoid mixed vaccine is used for heating the rabbits, and schizonepeta decoction or ethanol infusion is administered at 2g/kg for intragastric administration, so that the febrifuge mixed vaccine only has weak antipyretic effect. The herba Schizonepetae decoction has antipyretic and analgesic effects. D-menthone in the schizonepeta is a main analgesic component, and 3-methylcyclohexanone also has an analgesic effect. The divaricate saposhnikovia root has a bidirectional regulation effect, can sweat and stop sweating, can stop diarrhea, relax bowels, stop bleeding and dredge channels, so the application in clinic is relatively wide; the herba Menthae contains menthol, and the substance has effects of refreshing breath, relieving abdominal pain and cholecystspasm, resisting corrosion, killing bacteria, promoting urination, eliminating phlegm, invigorating stomach, promoting digestion, etc., and can be used for treating headache and myalgia. The ginger alcohol extract has an exciting effect on the blood vessel movement center and the respiratory center of the anesthetized cat. The chrysanthemum extract is injected into abdominal cavity of mouse, so that the diffusion of local trypan blue injected into intradermal tissue amine is small, the capillary resistance can be enhanced, and the chrysanthemum extract can inhibit the permeability of capillary and has anti-inflammatory effect. The Bulbus Allii Fistulosi has effect in inhibiting Shigella shigella in vitro, and the water infusion is diluted with test tube at a ratio of 1:10 to inhibit Trichophyton schoenleinii and Microsporum ozoloides, and has antibacterial and antifungal effects.
The navel-applying therapy with traditional Chinese medicine refers to an external treatment method for preventing and treating diseases by applying traditional Chinese medicine on the navel (Shenque acupoint) and combining moxibustion or hot ironing under the guidance of holistic concept and treatment principle of syndrome differentiation, so that the medicine stimulates qi of meridians and collaterals, dredges qi and blood, and regulates viscera by virtue of the force of moxibustion and the nature of moxibustion. Modern researches find that drug molecules and all physical molecules easily penetrate through the horny layer of the umbilical skin, enter intercellular substance and rapidly diffuse into blood to reach the whole body; meanwhile, the medicine can quickly form physical vapor pressure under body temperature or other heat sources, so that action potentials of tissue cells can be converted into nerve impulses, and the self-regulation function of the organism is mobilized through the reflection of the internal organs of the body, thereby achieving the purposes of regulating the functions of the internal organs, balancing yin and yang, strengthening the body resistance and eliminating evil.
The invention adopts angelica dahurica, biond magnolia flower, siberian cocklour fruit, fineleaf schizonepeta herb, divaricate saposhnikovia root, ginger, mint, fistular onion stalk and chrysanthemum to form the traditional Chinese medicine navel therapy prescription, and the angelica dahurica has the effects of dispelling cold and relieving exterior syndrome: dispelling pathogenic wind and relieving pain, and dredging nasal orifice, and can be used for treating common cold and wind cold, headache, nasal obstruction, migraine, supra-orbital bone pain, nasal discharge, and smellless odor, and is often combined with rhizoma Ligustici Chuanxiong, flos Magnoliae, fructus Xanthii, and radix Saposhnikoviae, and is described in compendium of materia Medica: for nasosinusitis, epistaxis, toothache and supra-orbital pain, the magnolia flower has the functions of dispelling wind-cold and relieving stuffy nose, and is used for wind-cold headache, nasal obstruction, nasosinusitis and thick nasal discharge, and it enters lung meridian and passes through nose to dispel wind-cold for treating thick nasal discharge, smelling neither smell nor odor, nasosinusitis and other symptoms in Chinese pharmacopoeia, and is often combined with dahurian angelica root, asarum herb, ledebouriella root, cocklebur fruit and the like. Xanthium sibiricum (materia Medica Mongolian fish pot): "Zhi headache and Shu Tong Tomen, Zhu Feng Du ren in marrow", has the actions of dispersing wind and alleviating pain, dispelling dampness and killing parasites. It is good at treating headache due to wind-cold, nasosinusitis and toothache. The three ingredients are used as monarch drugs to enhance the functions of relieving exterior syndrome, dispelling cold, ventilating lung, dredging orifices, dispelling wind and relieving pain. The clinical test results show that: the traditional Chinese medicine for treating chronic rhinitis by using the navel therapy has good curative effect, statistical difference (P is less than 0.05) exists between two groups, and the traditional Chinese medicine is simple, convenient and easy to implement, has no toxic or side effect, and is easy to accept by patients.
The traditional Chinese medicine raw materials with the mixture ratio integrate the drug effects of the traditional Chinese medicines, and are reasonably matched to enable the drug effects to be more thoroughly exerted, and meanwhile, the situation of drug effect offset among the traditional Chinese medicines is avoided. The medicine of the invention is researched by combining modern pharmacological action and modern pharmacodynamics, so that the medicines of the invention have the functions of enhancing immunologic function, resisting inflammation and inhibiting bacteria after being reasonably matched. And the selected raw materials of various Chinese patent medicines have low cost, are suitable for large-scale production and are convenient for more patients to use clinically.
The specific use method of the medicine comprises the following steps: the application method comprises mixing 1-3g of the powder with boiling water, making into soft paste, applying to umbilical region of patient, performing warm moxibustion with moxa stick or moxa wool, and fixing the medicine on umbilical region with adhesive plaster for 6-8 hr.
In conclusion, the medicament and the preparation method thereof provided by the invention fully exert the medicinal effects of various components, and the medicament finally prepared into the navel can be used for direct administration on the navel, is more favorable for remarkable absorption effect, has quick response time, is convenient for clinical application, is convenient to carry, has low cost, has the effects of dispersing lung qi, relieving exterior syndrome, dispelling wind and cold, relieving stuffy nose, strengthening body resistance and eliminating evil, can effectively improve the clinical symptoms of nasal obstruction, dyspnea, sneeze, watery nasal discharge, headache, dizziness and the like of patients with chronic rhinitis, has remarkable clinical treatment effect and lasting curative effect, and has the total effective rate of over 90 percent through comparison and observation of clinical effects.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein, and any reference thereto is therefore intended to be embraced therein.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims (4)

1. A traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy is characterized by comprising the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
2. The traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy according to claim 1, which is characterized in that: the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
3. The traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy according to claim 1, which is characterized in that: the traditional Chinese medicine composition is powder.
4. The traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy according to claim 1, which is characterized in that: the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: sun drying radix Angelicae Dahuricae, flos Magnoliae, fructus Xanthii, herba Schizonepetae, radix Saposhnikoviae, rhizoma Zingiberis recens, herba Menthae, flos Chrysanthemi and Bulbus Allii Fistulosi respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
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CN114191533A (en) * 2021-12-29 2022-03-18 潍坊医学院附属医院 Navel treatment traditional Chinese medicine preparation for treating allergic rhinitis and preparation method thereof

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CN114191533A (en) * 2021-12-29 2022-03-18 潍坊医学院附属医院 Navel treatment traditional Chinese medicine preparation for treating allergic rhinitis and preparation method thereof
CN114191533B (en) * 2021-12-29 2022-09-16 潍坊医学院附属医院 Navel-therapy traditional Chinese medicine preparation for treating allergic rhinitis and preparation method thereof

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