CN1814094A - Fat-reducing health-care product - Google Patents
Fat-reducing health-care product Download PDFInfo
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- CN1814094A CN1814094A CN 200510032589 CN200510032589A CN1814094A CN 1814094 A CN1814094 A CN 1814094A CN 200510032589 CN200510032589 CN 200510032589 CN 200510032589 A CN200510032589 A CN 200510032589A CN 1814094 A CN1814094 A CN 1814094A
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Abstract
The invention discloses a weight-reducing health product, prepared mainly of the following raw materials in weight shares: 10-30 shares of European Hop Flower extract comprising Humulus scandens flavonoid glycosides in 50-70%, 30-50 shares of Dogbane Leaf extract conmprising Ruta graveolens isoflavones in 60-80% and 10-30 shares of Areca Seed extract comprising arecoline in 50-70%; and auxiliary materials are added to make it into oral solution, capsules, wine preparation or solid product. The invention extracts active components from natural plants and scientifically and reasonably combines them and prepares the mixture into weight-reducing, fatness-preventing health products in various forms, having advantages of remarkable effect and no side effect.
Description
Technical field
The present invention relates to a kind of slimming health product, particularly a kind of by the synthetic slimming health product of Flos lupuli (Flos Humuli Lupuli), Folium Apocyni Veneti and Semen Arecae extract.
Background technology
Obesity is not a kind of sign of health, modern medicine is thought, obesity can cause various diseases, as hyperlipidemia, hypertension, hyperglycemia, fatty liver, liver cirrhosis, move the slow-witted disease of chronic hepatitis, coronary heart disease, cardiovascular disease, gout, cholelithiasis, cholecystitis, diabetes, pancreatitis, cerebral arteriosclerosis, cerebral thrombosis, brain function imbalance, disturbance of cerebral circulation, apoplexy, hemiplegia, numb limbs and tense tendons, disease, insomnia, forgetful, osteoporosis diseases.
The crowd who suffers from obesity, from teenager, teenager, child, in having expanded to always, old age etc. all kinds of crowds, and annual all with 3～7% speed increase.Therefore, the fat important topic that has become medical science, pharmacy and threpsology of prevention and treatment.At present, existing various types of diet products on the market, from outside use for oral administrationly, be three to spend eight, of a great variety.But these diet products have bigger side effect mostly.
Summary of the invention
The objective of the invention is to use natural plants, extract the natural activity composition, according to pharmacology, drug effect, the toxicologic research of natural activity composition, scientific and reasonable to be combined into a kind of toxic and side effects little, and the obvious results slimming health product.
For realizing above-mentioned purpose, this slimming health product is mainly made by following bulk drugs: contain glycosides million 50～70% 10～30 parts of Flos lupuli (Flos Humuli Lupuli) extracts, contain glycosides million 60～80% 30～50 parts of dogbane leaf extractives, contain 10～30 parts of the Semen Arecae extracts of arecoline 50～70%.
The preparation process of described Flos lupuli (Flos Humuli Lupuli) extract is as follows: after getting the pulverizing of Flos lupuli (Flos Humuli Lupuli) herb dry product, with 80% ethanol heating and refluxing extraction thing, ethanol is merged recovery, collect alcoholic extract, handle with silica gel and methanol, get first wine made of broomcorn millet thing, reclaim under reduced pressure methanol obtains the Flos lupuli (Flos Humuli Lupuli) herb extract, with 0.1N hydrochloric acid heating 30 minutes, add ethyl acetate extraction three times, merge back evaporated under reduced pressure ethyl acetate, obtain extract powder, with Lu oxadiazon A is standard substance, survey its total flavone glucoside unit with the UV method, content is the Flos lupuli (Flos Humuli Lupuli) extract that the present invention uses 50～70%;
The preparation process of described dogbane leaf extractive is as follows: after getting Folium Apocyni Veneti (herb dry product) pulverizing, with 80% acetone heating and refluxing extraction three times, acetone extract is filtered, after the merging, extractum reuse D101 resin treatment after the recovery, collect the ethanol eluent, reclaim under reduced pressure ethanol obtains extractum, with globulariacitrin (rutin) is standard substance, survey the total content of its total flavone glucoside unit with the UV method,, be the dogbane leaf extractive that the present invention uses at 60～80% o'clock;
The preparation process of described Semen Arecae extract is as follows: after the Semen Arecae dry fruit is pulverized, with 70% ethanol heating and refluxing extraction three times, merge alcoholic extract, reclaim under reduced pressure ethanol, obtain Bin extractum, handle with polyamide, collect the sodium carbonate washing liquid, the evaporated under reduced pressure sodium carbonate, obtain the extractum arecae powder, with arecoline A is standard substance, surveys its total alkaloid content with titrimetry, is Semen Arecae extract of the present invention 50%～70%.
Above-mentioned slimming health product is mainly made by following bulk drugs: 15～25 parts of Flos lupuli (Flos Humuli Lupuli) extracts, 35～40 parts of dogbane leaf extractives, 15～25 parts of Semen Arecae extracts.
Above-mentioned slimming health product is mainly made by following bulk drugs: 20 parts of Flos lupuli (Flos Humuli Lupuli) extracts, 30 parts of dogbane leaf extractives, 15 parts of Semen Arecae extracts.
Medical research is thought among the obese patient, deleterious composition is a saturated fat, it is that a class is difficult for by the fat that transforms, drains, absorbs, it is accumulated in the human body, in blood vessel, precipitate, perhaps be accumulated to the liver position, thereby cause various diseases, therefore, remove the meaning that saturated fat is only fat-reducing from overweight people's body is internal energy.Employed Flos lupuli (Flos Humuli Lupuli) extract among the present invention contains the natural components of Herba humuli scandentis flavone glycoside metaclass.Pharmacodynamic study confirms that Herba humuli scandentis flavone glycoside unit can remove the fat on the blood vessel wall significantly, and the remarkable result of prevention fatty liver is arranged.The dogbane leaf extractive that uses among the present invention contains Folium Symplocoris Caudatae flavonoid glycoside, and Folium Symplocoris Caudatae flavonoid glycoside has the unsaturated fatty effect of significant degraded, and pharmacodynamic study confirms that obviously blood viscosity lowering can be removed the free radical in the blood.Semen Arecae extract among the present invention contains arecoline, and the fat-reducing effect of arecoline early has the basis of clinical research and social life practice, and Hunan custom of chewing Semen Arecae among the people has confirmed the effect that it has prevention of obesity.Arecoline not only can suppress the absorption of cell to fat, and it also have and Flos lupuli (Flos Humuli Lupuli) and Folium Apocyni Veneti in the Lu grass glycosides million and the Folium Symplocoris Caudatae flavonoid glycoside that extract produce coordination drug effect effect, strengthen Flos lupuli (Flos Humuli Lupuli) extract and dogbane leaf extractive and suppress fat effect, and also have row's fat, transform unsaturated fatty effect, thereby realize fat-reducing, suppress fat purpose to the obese patient.
The present invention extracts the natural activity composition of Flos lupuli (Flos Humuli Lupuli), Folium Apocyni Veneti and Semen Arecae, pharmacology, drug effect, toxicologic research according to the natural activity composition, the scientific and reasonable prescription for losing weight that is combined into, can effectively and fast remove the intravital saturated fat of people, also can suppress the accumulation of saturated fat simultaneously at human body, it is little to have toxic and side effects, the obvious results advantage.
The specific embodiment
1, get Flos lupuli (Flos Humuli Lupuli) herb dry product 1000 grams, after the pulverizing, alcohol-pickled with 5000ml80%, heating and refluxing extraction in water-bath then, the time is 2～3 hours, filters alcoholic extract then, triplicate like this, merge three times ethanol liquid, the 2.0Pa recovered alcohol that reduces pressure gets extract 100～150 grams, stir evenly with 500 gram silica gel, use dissolve with methanol 500ml, the 2.5Pa that reduces pressure reclaims methanol, and extractum is heated with 1000ml0.1N hydrochloric acid, add 300ml * 3 ethyl acetate extractions after 30 minutes again, combined ethyl acetate, the 3.0Pa that reduces pressure reclaims ethyl acetate, obtains extract powder.With Lu oxadiazon A is standard substance, surveys certain some glycosides million content under UV, reaches 50～70% and is the Flos lupuli (Flos Humuli Lupuli) extract that the present invention uses, and is called for short the A composition.
2, get Folium Apocyni Veneti herb dry product 1000 grams, after the pulverizing, in water-bath, add gesture with 6000ml acetone and reflux, time is 2～3 hours, extracts three times, filters acetone recovery acetone and gets extractum, handle with D101 resin 500 grams, collect the ethanol eluent, 2.5Pa recovered alcohol then reduces pressure, obtain extractum, with rutin is standard substance, surveys its total flavone glucoside content under UV, reaches 60～80%, be the Herba Apocyni veneti extract that the present invention uses, be called for short the B composition.
3, get Semen Arecae dry fruit 1000 grams, after the pulverizing, with 5000ml70% ethanol reflux in water-bath, extract each 2～3 hours three times, merge alcoholic extract, the 2.0Pa recovered alcohol that reduces pressure is handled extract reuse 1000 gram polyamides, collects 0.5% sodium carbonate eluent, the 1.5Pa that reduces pressure reclaims solvent, with extract evaporate to dryness, pulverizing.With arecoline A was standard substance, and titrimetry is surveyed its total alkaloid content, was Semen Arecae extract of the present invention at 50%～70% o'clock, was called for short the C composition.
Example one: with A composition 10 grams, B composition 50 grams, C composition 20 grams add adjuvant 275 grams (starch), stir, and are circulated into 1
#Capsule, every weight 400mg, sterilization treatment is pressed hygiology and capsule health-care product quality standard detection then, is capsule product of the present invention after qualified.
Example two: with A composition 20 grams, B composition 40 grams, C composition 30 grams add adjuvant (mannan) and stir, and are circulated into 0
#Capsule, every weight 500mg carries out sterilization treatment then, presses hygiology and the standard test of capsule health-care product quality, is capsule product of the present invention after qualified.
Example three: with A composition 10 grams, B composition 50 grams, C composition 20 grams, with the molten angle of 1000ml wine, filtration sterilization, pour into every bottle of 50ml (every bottle contains A+B+C composition 400mg) then, press hygiology and health product medicated wine then and detect, be fat-reducing medicated wine product of the present invention after qualified.
Example four: with A composition 30 grams, B composition 30 grams, C composition 10 grams, with 10000ml38 ° of soaking in Chinese liquor, after-filtration sterilization in 24 hours is circulated into 50ml bottle (every bottle contains A+B+C composition 350mg), press hygiology and health product medicated wine then and detect, be fat-reducing medicated wine product of the present invention after qualified.
Example five: with A composition 20 grams, B composition 40 grams, C composition 30 grams, use the 10000ml dissolved in distilled water, filter the back and add glucide 20 grams, sucrose 100 grams, sodium benzoate 50 grams, protein sugar 10 grams, essence is an amount of, and dissolving back sterilization treatment is pressed hygiology and oral liquid health product quality standard detection then, after qualified, by (every bottle contains A+B+C composition 90mg) in every filling bottle of 10ml.Using method: fat-reducing consumption: everyone/time one bottle, one day three times; Prevention of obesity, everyone/time one bottle, one day one bottle.This is an oral liquid product of the present invention.
Claims (5)
1, a kind of slimming health product is characterized in that it is mainly made by following bulk drugs: contain glycosides million 50～70% 10～30 parts of Flos lupuli (Flos Humuli Lupuli) extracts, contain glycosides million 60～80% 30～50 parts of dogbane leaf extractives, contain 10～30 parts of the Semen Arecae extracts of arecoline 50～70%;
The preparation process of described Flos lupuli (Flos Humuli Lupuli) extract is as follows: after getting the pulverizing of Flos lupuli (Flos Humuli Lupuli) herb dry product, with 80% ethanol heating and refluxing extraction thing, ethanol is merged recovery, collect alcoholic extract, handle with silica gel and methanol, get the methanol thing, reclaim under reduced pressure methanol obtains the Flos lupuli (Flos Humuli Lupuli) herb extract, with 0.1N hydrochloric acid heating 30 minutes, add ethyl acetate extraction three times, merge back evaporated under reduced pressure ethyl acetate, obtain extract powder, with .alpha.-bitter acid A is standard substance, survey its total flavone glucoside unit with the UV method, content is the Flos lupuli (Flos Humuli Lupuli) extract that the present invention uses 50～70%;
The preparation process of described dogbane leaf extractive is as follows: after getting the pulverizing of Folium Apocyni Veneti herb dry product, with 80% acetone heating and refluxing extraction three times, acetone extract is filtered, after the merging, extractum reuse D101 resin treatment after the recovery, collect the ethanol eluent, reclaim under reduced pressure ethanol obtains extractum, with globulariacitrin is standard substance, survey the total content of its total flavone glucoside unit with the UV method,, be the dogbane leaf extractive that the present invention uses at 60～80% o'clock;
The preparation process of described Semen Arecae extract is as follows: after the Semen Arecae dry fruit is pulverized, with 70% ethanol heating and refluxing extraction three times, merge alcoholic extract, reclaim under reduced pressure ethanol, obtain extractum arecae, handle with polyamide, collect the sodium carbonate washing liquid, the evaporated under reduced pressure sodium carbonate, obtain the extractum arecae powder, with arecoline A is standard substance, surveys its total alkaloid content with titrimetry, is Semen Arecae extract of the present invention 50%～70%.
2, according to right 1 described slimming health product, it is characterized in that: 15～25 parts of Flos lupuli (Flos Humuli Lupuli) extracts, 35～40 parts of dogbane leaf extractives, 15～25 parts of Semen Arecae extracts.
3, according to right 1 described slimming health product, it is characterized in that: 20 parts of Flos lupuli (Flos Humuli Lupuli) extracts, 30 parts of dogbane leaf extractives, 15 parts of Semen Arecae extracts.
4, according to right 1 or 2 or 3 described slimming health products, it is characterized in that: can add adjuvant and make agent shape or solid products such as oral liquid, capsule, medicated wine.
5, slimming health product according to claim 4 is characterized in that: described adjuvant is starch, mannan, wine or Chinese liquor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100325894A CN100394953C (en) | 2005-12-21 | 2005-12-21 | Fat-reducing health-care product |
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2005100325894A CN100394953C (en) | 2005-12-21 | 2005-12-21 | Fat-reducing health-care product |
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| Publication Number | Publication Date |
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| CN1814094A true CN1814094A (en) | 2006-08-09 |
| CN100394953C CN100394953C (en) | 2008-06-18 |
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| CNB2005100325894A Expired - Fee Related CN100394953C (en) | 2005-12-21 | 2005-12-21 | Fat-reducing health-care product |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101147612B (en) * | 2007-01-16 | 2011-06-01 | 李明 | Five health-care soft beverage |
| CN102861130A (en) * | 2012-10-25 | 2013-01-09 | 乌鲁木齐创新源生物科技有限公司 | Preparation method of hops total flavone with hops stem and leaf and imperfect flower as raw materials |
| CN103859389A (en) * | 2012-12-14 | 2014-06-18 | 梁三妹 | Weight-reducing health-care product and preparation method thereof |
| CN104320981A (en) * | 2012-03-07 | 2015-01-28 | 孙元禄 | Use of humulus japonicus extract for preventing or treating metabolic disorders or fatty liver |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1029742C (en) * | 1992-03-17 | 1995-09-13 | 西安汉斯啤酒饮料总厂 | Method for producing gynostemium pentaphylla beer |
| CN1157103A (en) * | 1996-02-16 | 1997-08-20 | 徐树根 | Tieguanyin weight-reducing tea |
-
2005
- 2005-12-21 CN CNB2005100325894A patent/CN100394953C/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101147612B (en) * | 2007-01-16 | 2011-06-01 | 李明 | Five health-care soft beverage |
| CN104320981A (en) * | 2012-03-07 | 2015-01-28 | 孙元禄 | Use of humulus japonicus extract for preventing or treating metabolic disorders or fatty liver |
| EP2823717B1 (en) * | 2012-03-07 | 2018-02-21 | Yuan Lu Sun | Humulus japonicus extract for preventing or treating obesity, hyperlipidemia or fatty liver |
| CN102861130A (en) * | 2012-10-25 | 2013-01-09 | 乌鲁木齐创新源生物科技有限公司 | Preparation method of hops total flavone with hops stem and leaf and imperfect flower as raw materials |
| CN103859389A (en) * | 2012-12-14 | 2014-06-18 | 梁三妹 | Weight-reducing health-care product and preparation method thereof |
| CN103859389B (en) * | 2012-12-14 | 2016-12-07 | 布伟年 | A kind of slimming health product and preparation method thereof |
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| CN100394953C (en) | 2008-06-18 |
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Granted publication date: 20080618 Termination date: 20101221 |