CN1792217A - Additives of fodder for improving intestines function of piglings - Google Patents
Additives of fodder for improving intestines function of piglings Download PDFInfo
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- CN1792217A CN1792217A CNA2005100970475A CN200510097047A CN1792217A CN 1792217 A CN1792217 A CN 1792217A CN A2005100970475 A CNA2005100970475 A CN A2005100970475A CN 200510097047 A CN200510097047 A CN 200510097047A CN 1792217 A CN1792217 A CN 1792217A
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- glutamine
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- vitamin
- glucose
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- 210000000936 intestine Anatomy 0.000 title claims description 71
- 239000000654 additive Substances 0.000 title abstract description 4
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims abstract description 56
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 54
- 239000008103 glucose Substances 0.000 claims abstract description 54
- MFBOGIVSZKQAPD-UHFFFAOYSA-M sodium butyrate Chemical compound [Na+].CCCC([O-])=O MFBOGIVSZKQAPD-UHFFFAOYSA-M 0.000 claims abstract description 52
- PNMUAGGSDZXTHX-BYPYZUCNSA-N Gly-Gln Chemical compound NCC(=O)N[C@H](C(O)=O)CCC(N)=O PNMUAGGSDZXTHX-BYPYZUCNSA-N 0.000 claims abstract description 39
- 108010010147 glycylglutamine Proteins 0.000 claims abstract description 38
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 claims abstract description 27
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 102
- 230000001737 promoting effect Effects 0.000 claims description 57
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 51
- 229930003268 Vitamin C Natural products 0.000 claims description 51
- 239000000463 material Substances 0.000 claims description 51
- 235000019154 vitamin C Nutrition 0.000 claims description 51
- 239000011718 vitamin C Substances 0.000 claims description 51
- 206010012735 Diarrhoea Diseases 0.000 abstract description 10
- 230000000996 additive effect Effects 0.000 abstract description 3
- 239000000843 powder Substances 0.000 abstract description 3
- 238000006243 chemical reaction Methods 0.000 abstract description 2
- 102000007562 Serum Albumin Human genes 0.000 abstract 1
- 108010071390 Serum Albumin Proteins 0.000 abstract 1
- 230000003871 intestinal function Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 description 43
- 241000282898 Sus scrofa Species 0.000 description 22
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 10
- 238000004519 manufacturing process Methods 0.000 description 6
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 5
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 5
- 230000000968 intestinal effect Effects 0.000 description 5
- 210000002966 serum Anatomy 0.000 description 5
- 241000282887 Suidae Species 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 210000004347 intestinal mucosa Anatomy 0.000 description 4
- 208000011580 syndromic disease Diseases 0.000 description 4
- 150000001413 amino acids Chemical class 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 230000003750 conditioning effect Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- BXMVKQIIJSXIBU-UHFFFAOYSA-N (2,5-dioxopyrrolidin-1-yl) diphenyl phosphate Chemical compound O=C1CCC(=O)N1OP(=O)(OC=1C=CC=CC=1)OC1=CC=CC=C1 BXMVKQIIJSXIBU-UHFFFAOYSA-N 0.000 description 2
- KDCGOANMDULRCW-UHFFFAOYSA-N 7H-purine Chemical compound N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 description 2
- 108010016626 Dipeptides Proteins 0.000 description 2
- 108060003951 Immunoglobulin Proteins 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 230000029087 digestion Effects 0.000 description 2
- 230000006862 enzymatic digestion Effects 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 102000018358 immunoglobulin Human genes 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 210000002381 plasma Anatomy 0.000 description 2
- 210000000813 small intestine Anatomy 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 241000321096 Adenoides Species 0.000 description 1
- 239000004382 Amylase Substances 0.000 description 1
- 102000013142 Amylases Human genes 0.000 description 1
- 108010065511 Amylases Proteins 0.000 description 1
- 239000000592 Artificial Cell Substances 0.000 description 1
- 206010003694 Atrophy Diseases 0.000 description 1
- FERIUCNNQQJTOY-UHFFFAOYSA-M Butyrate Chemical compound CCCC([O-])=O FERIUCNNQQJTOY-UHFFFAOYSA-M 0.000 description 1
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Natural products CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 description 1
- 102000004860 Dipeptidases Human genes 0.000 description 1
- 108090001081 Dipeptidases Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 210000002534 adenoid Anatomy 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 210000001198 duodenum Anatomy 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000000446 fuel Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 235000020256 human milk Nutrition 0.000 description 1
- 210000004251 human milk Anatomy 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000007365 immunoregulation Effects 0.000 description 1
- 230000008944 intestinal immunity Effects 0.000 description 1
- 210000002011 intestinal secretion Anatomy 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000019629 palatability Nutrition 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 235000015277 pork Nutrition 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000002213 purine nucleotide Substances 0.000 description 1
- 239000002719 pyrimidine nucleotide Substances 0.000 description 1
- 150000003230 pyrimidines Chemical class 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 210000004885 white matter Anatomy 0.000 description 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
An additive of feed for improving the intestinal function of piglet is prepared from three or more of glutamine, glycyl-L-glutamine, sodium butyrate, VC and glucose. It can be used to replace the plasma albumin powder to prevent diarrhea and increase the conversion rate of feed and the growth speed of piglet.
Description
Technical field
The present invention relates to a kind of feed addictive of promoting intestines function of piglings.
Background technology
In the Swine Production, the key link is weanling pig production, early weaning piglet is the advanced technology of common concern during domestic and international intensive pig production is produced, early weaning can improve the breeding potential of sow, can increase the year litter size of sow, minimizing is by the transmission of parent to piglet, and can improve production performance and the carcass quality of growth pig, and usage ratio of equipment such as delivery room is improved.The country of pig industry prosperity has at present begun to apply 14 age in days ultra-early weaning technology.But the major issue that early weaning brings is how to improve the growth performance of weanling pig, because the growth performance of weanling pig not only is related to the level of production and the economic benefit in piglet stage, and be related to the production performance and the economic benefit in the whole growth stage of pig, the raising of piglet early growth performance can make the growth of later stage performance be greatly improved, and the marketing time of shortening pork pig, bring bigger economic benefit thereby give to raise pigs to produce.But the raising of the growth performance of weanling pig also is the most scabrous ring in the whole link of raising pigs.Because during the piglet birth, its alimentary canal fails fully to adapt to the digestion and the utilization (Rhoads of breast milk, 1990), great change has taken place in the character of daily ration behind the weaned piglet, and piglet alimentary canal zoon not as yet, the digestive enzyme activity deficiency, immunologic function is undeveloped mature (Aumaitre andCorring still also, 1978), and wean not only is related to physiological variation, psychology, variation has also taken place in environment and nutrition condition, thereby it is poor often to show as appetite, the disorders of digestion, diarrhoea, growthing lag, efficiency of feed utilization is low etc. so-called " early weaning piglet syndrome ".
The research that solves " early weaning piglet syndrome " is scientific worker's the research focus of raising pigs at present, for example, utilize the pig blood resource of large-scale slaughterhouse health, adopt advanced separation, modified, spray-drying blood plasma (ball) albumen powder that drying process with atomizing is produced, because of it has good palatability, the protein content height, amino acid balance and kept characteristics such as immune globulin activity in the blood plasma and be used as the technical measures of solution " early weaning piglet syndrome ".But owing to the use that is under an embargo of bio-safety problem.
Studies show that in a large number glutamine (GLN) is the fuel of intestinal cell, it is the precursor that synthetic cell breaks up necessary purine and pyrimidine nucleotide, be mesenterium lymph and last theliolymphocyte and significant energy substrate, be to keep the adenoid essential composition relevant with enteron aisle, it also is the essential material of synthetic intestinal secretion immune globulin white matter, keeping the enteron aisle normal function and improving play an important role aspect the intestine immunity power (James, 1998).And GLN is the rich in amino acid of pig Ruzhong content, and it is the underlying cause (Alverdy, 1990) that the early weaning piglet syndrome produces that wean back GLN supply reduces.GLN, glucose, butyrate, propionate and acetate all are energy sources of intestinal mucosa cell, and wherein GLN is the energy source of most important intestinal mucosa cell, and glucose takes second place.GLN dipeptides (as Gly-L-Gln) main form with dipeptides in small intestine absorbs, the absorptivity height, being decomposed into the amino acid of its composition after absorbing by the dipeptidase in the histoorgans such as small intestine, can overcoming the thermal instability and the low solubility of GLN monomer, also is effective addition manner of a kind of GLN.
Summary of the invention
The invention provides a kind of feed addictive of promoting intestines function of piglings.
The feed addictive of promoting intestines function of piglings is formulated in proportion by the material more than three kinds or three kinds in glutamine, glycyl-L-glutamine, sodium butyrate, vitamin C and five kinds of materials of glucose.
Various material proportionings are as follows in the feed addictive of enhancement intestines function of piglings:
1) glutamine: sodium butyrate: the vitamin C ratio is 1: 0.05~10: 0.1~10.
2) glutamine: sodium butyrate: the glucose ratio is 1: 0.05~10: 1~100.
3) glutamine: vitamin C: the glucose ratio is 1: 0.1~10: 1~100.
4) glutamine: sodium butyrate: vitamin C: the glucose ratio is 1: 0.05~10: 0.1~10: 1~100.
5) glycyl-L-glutamine: sodium butyrate: the vitamin C ratio is 1: 0.1~10: 0.1~10.
6) glycyl-L-glutamine: sodium butyrate: the glucose ratio is 1: 0.1~10: 1~100.
7) glycyl-L-glutamine: vitamin C: the glucose ratio is 1: 0.1~10: 1~100.
8) glycyl-L-glutamine: sodium butyrate: vitamin C: the glucose ratio is 1: 0.1~10: 0.1~10: 1~100.
9) glutamine: glycyl-L-glutamine: sodium butyrate: vitamin C: the glucose ratio is 1: 0.1~10: 0.1~10: 0.1~10: 1~100.
Above-mentioned compound is mixed, promoted the feed addictive of intestines function of piglings accordingly.
The present invention starts with from the digestive physiology development characteristics of piglet, applied nutrition and immunoregulation means, multiple active material with raising function of intestinal canal, enhancing digestive enzyme activity and raising immunity is carried out the reasonable compatibility combination, successfully developed a kind of feed addictive of promoting intestines function of piglings.Use the feed addictive of enhancement intestines function of piglings of the present invention, can prevent the intensification of the excessive atrophy of intestinal mucosa fine hair in 1~7 day and crypts behind the weaned piglet, can significantly improve 8~14 days intestinal mucosa height of naps in wean back, weanling pig duodenum content total protease activity can be significantly improved, the amylase activity of back 14 days weanling pigs of wean can be significantly improved.Use the feed addictive of enhancement intestines function of piglings of the present invention, can significantly improve the average daily gain of weanling pig, reduce the post-weaning diarrhea in piglet rate, shorten the diarrhoea cycle.Promote the complete replacement blood slurry protein powder of feed addictive energy of intestines function of piglings, have remarkable economic efficiency and social benefit, market prospects are wide.
The feed addictive that adds 0.05~2% enhancement intestines function of piglings of the present invention on the basis of mixed feed is fed, and can obviously reduce the diarrhea rate of piglet, improves daily gain, improves food conversion ratio.The alternative SDPP of the feed addictive of enhancement intestines function of piglings of the present invention is avoided in response to the bio-safety problem that causes with SDPP.Detect through Multitest and laboratory, the not only efficient and safety non-toxic of this additive, the animal product of being fed meets the food hygiene requirement.
The specific embodiment
The feed addictive of promoting intestines function of piglings is Powdered, be that compound with this powdery adds in mixed feed, concentrated feed, premix or the additive during application, and evenly mix, its addition is amounted in the mixed feed content and is counted 0.05~2%.
Embodiment 1
Glutamine, sodium butyrate and three kinds of materials of vitamin C are made up with 1: 0.05: 10 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 2
Glutamine, sodium butyrate and three kinds of materials of vitamin C are made up with 1: 10: 0.1 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 3
Glutamine, sodium butyrate and three kinds of materials of vitamin C are made up with 1: 5: 5.05 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 4
Glutamine, sodium butyrate and three kinds of materials of glucose are made up with 1: 0.05: 100 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 5
Glutamine, sodium butyrate and three kinds of materials of glucose are made up with 1: 10: 1 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 6
Glutamine, sodium butyrate and three kinds of materials of glucose are made up with 1: 5.03: 50.5 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 7
Glutamine, vitamin C and three kinds of materials of glucose are made up with 1: 0.1: 100 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 8
Glutamine, vitamin C and three kinds of materials of glucose are made up with 1: 10: 1 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 9
Glutamine, vitamin C and three kinds of materials of glucose are made up with 1: 5.05: 50.5 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 10
With glutamine, sodium butyrate, vitamin C and four kinds of materials of glucose with 1: 0.05: 10: 100 ratios combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 11
With glutamine, sodium butyrate, vitamin C and four kinds of materials of glucose with 1: 10: 0.1: 1 ratio combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 12
With glutamine, sodium butyrate, vitamin C and four kinds of materials of glucose with 1: 5.03: 5.05: 50.5 ratios combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 13
With glutamine, sodium butyrate, vitamin C and four kinds of materials of glucose with 1: 10: 0.1: 100 ratios combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 14
With glutamine, sodium butyrate, vitamin C and four kinds of materials of glucose with 1: 0.05: 10: 1 ratio combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 15
With glutamine, sodium butyrate, vitamin C and four kinds of materials of glucose with 1: 10: 10: 1 ratio combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 16
With glutamine, sodium butyrate, vitamin C and four kinds of materials of glucose with 1: 0.05: 0.1: 100 ratios combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 17
Glycyl-L-glutamine, sodium butyrate and three kinds of materials of vitamin C are made up with 1: 0.1: 10 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 18
Glycyl-L-glutamine, sodium butyrate and three kinds of materials of vitamin C are made up with 1: 10: 0.1 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 19
Glycyl-L-glutamine, sodium butyrate and three kinds of materials of vitamin C are made up with 1: 5.05: 5.05 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 20
Glycyl-L-glutamine, sodium butyrate and three kinds of materials of glucose are made up with 1: 0.1: 100 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 21
Glycyl-L-glutamine, sodium butyrate and three kinds of materials of glucose are made up with 1: 10: 1 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 22
Glycyl-L-glutamine, sodium butyrate and three kinds of materials of glucose are made up with 1: 5.05: 50.5 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 23
Glycyl-L-glutamine, vitamin C and three kinds of materials of glucose are made up with 1: 0.1: 100 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 24
Glycyl-L-glutamine, vitamin C and three kinds of materials of glucose are made up with 1: 10: 1 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 25
Glycyl-L-glutamine, vitamin C and three kinds of materials of glucose are made up with 1: 5.05: 50.5 ratio, and above-mentioned compound is mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Embodiment 26
With glycyl-L-glutamine, sodium butyrate, vitamin C and four kinds of materials of glucose with 1: 0.1: 10: 100 ratios combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 27
With glycyl-L-glutamine, sodium butyrate, vitamin C and four kinds of materials of glucose with 1: 10: 0.1: 1 ratio combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 28
With glycyl-L-glutamine, sodium butyrate, vitamin C and four kinds of materials of glucose with 1: 10: 0.1: 100 ratios combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 29
With glycyl-L-glutamine, sodium butyrate, vitamin C and four kinds of materials of glucose with 1: 0.1: 10: 1 ratio combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 30
With glycyl-L-glutamine, sodium butyrate, vitamin C and four kinds of materials of glucose with 1: 10: 10: 1 ratio combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 31
With glycyl-L-glutamine, sodium butyrate, vitamin C and four kinds of materials of glucose with 1: 0.1: 0.1: 100 ratios combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 32
With glycyl-L-glutamine, sodium butyrate, vitamin C and four kinds of materials of glucose with 1: 5.05: 5.05: 50.5 ratios combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 33
With GLN, glycyl-L-glutamine, sodium butyrate, vitamin C and five kinds of materials of glucose with 1: 0.1: 10: 10: 100 ratios combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 34
With glutamine, glycyl-L-glutamine, sodium butyrate, vitamin C and five kinds of materials of glucose with 1: 10: 0.1: 0.1: 1 ratio combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 35
With glutamine, glycyl-L-glutamine, sodium butyrate, vitamin C and five kinds of materials of glucose with 1: 10: 0.1: 10: 100 ratios combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 36
With glutamine, glycyl-L-glutamine, sodium butyrate, vitamin C and five kinds of materials of glucose with 1: 0.1: 10: 0.1: 1 ratio combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 37
With glutamine, glycyl-L-glutamine, sodium butyrate, vitamin C and five kinds of materials of glucose with 1: 10: 10: 0.1: 100 ratio combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 38
With glutamine, glycyl-L-glutamine, sodium butyrate, vitamin C and five kinds of materials of glucose with 1: 0.1: 0.1: 10: 1 ratios combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 39
With glutamine, glycyl-L-glutamine, sodium butyrate, vitamin C and five kinds of materials of glucose with 1: 10: 10: 10: 1 ratios combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 40
With glutamine, glycyl-L-glutamine, sodium butyrate, vitamin C and five kinds of materials of glucose with 1: 0.1: 0.1: 0.1: 100 ratio combination, and above-mentioned compound mixed obtains a kind of feed addictive of promoting intestines function of piglings.
Embodiment 41
With glutamine, glycyl-L-glutamine, sodium butyrate, vitamin C and five kinds of materials of glucose with 1: 5.05: 5.05: 5.0.5: 50.5 ratios combinations, and above-mentioned compound mixed, obtain a kind of feed addictive of promoting intestines function of piglings.
Application Example 1
In 28 age in days weanling pig daily rations, add the feed addictive of 0.5% enhancement intestines function of piglings of the present invention, the influence of diarrhea of weaned piglets rate is seen Table-1.
Table-1 function of intestinal canal conditioning agent is to the influence of diarrhea rate
The piglet age in days | Control group | Test group |
28~35d 35~42d 42~49d | 24.60±3.64 A 27.73±4.96 A 6.34±1.37 A | 7.14±2.38 B 7.14±2.38 B 0.79±1.37 B |
Add the feed addictive of 0.5% enhancement intestines function of piglings of the present invention in the daily ration, 28~35 age in days stage of piglet diarrhea rate is than control group low by 70.98% (P<0.01); 35~42 age in days stage of piglet diarrhea rate is than control group low by 73.28% (P<0.01); 42~49 age in days stage of piglet diarrhea rate is than control group low by 87.54% (P<0.01).
Application Example 2
Add the feed addictive of 0.75% enhancement intestines function of piglings of the present invention in 28 age in days weanling pig daily rations, the influence of 28~42 age in days stages to weanling pig daily gain, material anharmonic ratio sees Table-2.
Table-2 function of intestinal canal conditioning agents are to the influence of weanling pig daily gain, material anharmonic ratio
Project | Control group | Test group |
Heavy (Kg) average daily gains of starting weight (Kg) 42 ages in days (g) material anharmonic ratio | 7.99±0.84 11.45±1.42a 246.7±10.1A 1.58±0.11a | 7.88±0.81 12.31±1.29b 316.4±8.1B 1.38±0.07b |
Add the feed addictive of 0.75% enhancement intestines function of piglings of the present invention in 28 age in days weanling pig daily rations, 28~42 age in days stages were improved 28.25% (P<0.01) to the weanling pig daily gain, material anharmonic ratio 12.66% (P<0.05).
Application Example 3
The feed addictive of interpolation 1% enhancement intestines function of piglings of the present invention sees Table-3 to the influence of the back serum xylose concentration that weans in 21 age in days weanling pig daily rations.
Table-3 function of intestinal canal conditioning agents are to the influence (mmol/L) of serum xylose concentration
Date 0d 7d 14d 21d | Control group 0.826 ± 0.043 0.153 ± 0.013A, 0.288 ± 0.033A, 0.447 ± 0.018A | Test II 0.826 ± 0.043 0.345 ± 0.019B, 0.583 ± 0.018B, 0.930 ± 0.044B |
In 21 age in days weanling pig daily rations, add the feed addictive of 1% enhancement intestines function of piglings of the present invention, wean back 1 all serum xylose concentrations are than control group high by 125.49% (P<0.01), wean back 2 all serum xylose concentrations are than control group high by 102.43% (P<0.01), and wean back 3 all serum xylose concentrations are than control group high by 108.05% (P<0.01).
Claims (10)
1. a feed addictive of promoting intestines function of piglings is characterized in that by the material more than three kinds or three kinds in glutamine, glycyl-L-glutamine, sodium butyrate, vitamin C and five kinds of materials of glucose formulated in proportion.
2. a kind of feed addictive of promoting intestines function of piglings according to claim 1 is characterized in that described glutamine: sodium butyrate: the vitamin C ratio is 1: 0.05~10: 0.1~10.
3. a kind of feed addictive of promoting intestines function of piglings according to claim 1 is characterized in that described glutamine: sodium butyrate: the glucose ratio is 1: 0.05~10: 1~100.
4. a kind of feed addictive of promoting intestines function of piglings according to claim 1 is characterized in that described glutamine: vitamin C: the glucose ratio is 1: 0.1~10: 1~100.
5. a kind of feed addictive of promoting intestines function of piglings according to claim 1 is characterized in that described glutamine: sodium butyrate: vitamin C: the glucose ratio is 1: 0.05~10: 0.1~10: 1~100.
6. a kind of feed addictive of promoting intestines function of piglings according to claim 1 is characterized in that described glycyl-L-glutamine: sodium butyrate: the vitamin C ratio is 1: 0.1~10: 0.1~10.
7. a kind of feed addictive of promoting intestines function of piglings according to claim 1 is characterized in that described glycyl-L-glutamine: sodium butyrate: the glucose ratio is 1: 0.1~10: 1~100.
8. a kind of feed addictive of promoting intestines function of piglings according to claim 1 is characterized in that described glycyl-L-glutamine: vitamin C: the glucose ratio is 1: 0.1~10: 1~100.
9. a kind of feed addictive of promoting intestines function of piglings according to claim 1 is characterized in that described glycyl-L-glutamine: sodium butyrate: vitamin C: the glucose ratio is 1: 0.1~10: 0.1~10: 1~100.
10. a kind of feed addictive of promoting intestines function of piglings according to claim 1 is characterized in that described glutamine: glycyl-L-glutamine: sodium butyrate: vitamin C: the glucose ratio is 1: 0.1~10: 0.1~10: 0.1~10: 1~100.
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