CN1750826A - R－10－羟基－10,11－二氢－卡马西平在神经病性疼痛中的应用 - Google Patents

R－10－羟基－10,11－二氢－卡马西平在神经病性疼痛中的应用 Download PDF

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Publication number
CN1750826A
CN1750826A CNA2004800044023A CN200480004402A CN1750826A CN 1750826 A CN1750826 A CN 1750826A CN A2004800044023 A CNA2004800044023 A CN A2004800044023A CN 200480004402 A CN200480004402 A CN 200480004402A CN 1750826 A CN1750826 A CN 1750826A
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CN
China
Prior art keywords
enantiomer
mixture
neuropathic pain
formula
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2004800044023A
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English (en)
Chinese (zh)
Inventor
A·福克斯
S·贝文
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of CN1750826A publication Critical patent/CN1750826A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
CNA2004800044023A 2003-02-17 2004-02-16 R－10－羟基－10,11－二氢－卡马西平在神经病性疼痛中的应用 Pending CN1750826A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0303615.9A GB0303615D0 (en) 2003-02-17 2003-02-17 Use of organic compounds
GB0303615.9 2003-02-17

Publications (1)

Publication Number Publication Date
CN1750826A true CN1750826A (zh) 2006-03-22

Family

ID=9953162

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2004800044023A Pending CN1750826A (zh) 2003-02-17 2004-02-16 R－10－羟基－10,11－二氢－卡马西平在神经病性疼痛中的应用

Country Status (11)

Country Link
US (3) US20060166967A1 (https=)
EP (1) EP1596865A1 (https=)
JP (1) JP2006517940A (https=)
CN (1) CN1750826A (https=)
AU (1) AU2004212327A1 (https=)
BR (1) BRPI0407529A (https=)
CA (1) CA2516265A1 (https=)
GB (1) GB0303615D0 (https=)
MX (1) MXPA05008711A (https=)
PL (1) PL376755A1 (https=)
WO (1) WO2004071513A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1879590A1 (en) * 2005-05-06 2008-01-23 Portela & Ca., S.A. Eslicarbazepine acetate and methods of use
US20060252745A1 (en) 2005-05-06 2006-11-09 Almeida Jose L D Methods of preparing pharmaceutical compositions comprising eslicarbazepine acetate and methods of use
GB0517740D0 (en) * 2005-08-31 2005-10-12 Novartis Ag Organic compounds
GB0603008D0 (en) * 2006-02-14 2006-03-29 Portela & Ca Sa Method
GB0700773D0 (en) 2007-01-15 2007-02-21 Portela & Ca Sa Drug therapies
WO2011017319A1 (en) * 2009-08-03 2011-02-10 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods of treating disorders associated with protein polymerization
US8809617B2 (en) 2009-11-05 2014-08-19 The University of Pittsburgh—Of the Commonwealth System of Higher Education Automated high-content live animal drug screening using C. elegans
US9072772B2 (en) 2009-11-05 2015-07-07 University of Pittsburgh—of the Commonwealth System of Higher Education Methods of treating disorders associated with protein aggregation
CN116063231A (zh) * 2021-10-29 2023-05-05 上药康丽（常州）药业有限公司 一种s-利卡西平的回收方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH505101A (de) * 1969-03-31 1971-03-31 Ciba Geigy Ag Verfahren zur Herstellung von neuen Azepinderivaten
EP0435826A1 (de) * 1989-12-27 1991-07-03 Ciba-Geigy Ag Intravenöse Lösungen für Status Epilepticus
US5534495A (en) * 1993-05-25 1996-07-09 Advanced Peptides And Biotechnology Sciences Treatment of non-HIV neuropathic pain syndromes
US5688830A (en) * 1996-01-25 1997-11-18 Syntex (U.S.A.) Inc. Treatment of neuropathic pain
GB0112812D0 (en) * 2001-05-25 2001-07-18 Portela & Ca Sa Mthd for preparation of 10, 11-dihydro-10-hydroxy-5H-dibenz/B,F/azepine-5-c arboxamide and 10,11-dihydro-10-oxo-5H-dibenz/B,F/azepine-5-carb oxamide therefrom
KR20050044396A (ko) * 2001-11-12 2005-05-12 노파르티스 아게 정동 및 주의력 장애 및 신경병성 통증 치료용 의약제조에 사용하기 위한 모노히드록시카르바마제핀
WO2004014391A1 (en) * 2002-08-06 2004-02-19 Novartis Ag Use of carboxamides for the treatment of tinnitus
GB0223224D0 (en) * 2002-10-07 2002-11-13 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
MXPA05008711A (es) 2005-10-05
EP1596865A1 (en) 2005-11-23
US20090054404A1 (en) 2009-02-26
WO2004071513A1 (en) 2004-08-26
PL376755A1 (pl) 2006-01-09
GB0303615D0 (en) 2003-03-19
US20060166967A1 (en) 2006-07-27
BRPI0407529A (pt) 2006-02-14
JP2006517940A (ja) 2006-08-03
AU2004212327A1 (en) 2004-08-26
CA2516265A1 (en) 2004-08-26
US20100120746A1 (en) 2010-05-13

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