CN1739753A - Psoriasis treating Chinese medicine prepn and its pren process - Google Patents
Psoriasis treating Chinese medicine prepn and its pren process Download PDFInfo
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Abstract
The psoriasis treating Chinese medicine preparation is prepared through slicing and alcohol reflux extract red sage and peony bark to obtain medicine liquid, concentration, drying and crushing to obtain fine alcohol extracted powder; decocting gromwell, skullcap root, dittany bark and other eight kinds of Chinese medicinal materials together with the alcohol extracted dregs, concentration, sucking filtering after adding alcohol, concentration, drying, crushing to obtain decoction powder; mixing the fine alcohol extracted powder and the decoction powder and drying to obtain mixed medicine powder. The present invention is superior to similar medicines, and can cure psoriasis radically.
Description
Technical field
The present invention relates to psoriatic Chinese medicine preparation of a kind of treatment and preparation method thereof.
Background technology
At present, treat psoriatic method and mainly contain sleep therapy, therapy of blood-letting, injection treatment, Chinese medicine decoction, apply medicinal lotion or ointment water ointment etc. and hormone medicine for oral administration, immunosuppressant and anticancer class medicine etc. outward.Though each is effective in cure for existing these class methods or medicine, all has in various degree defective or deficiency.The class medicine for oral administration that has not only easily causes hypercorticalismus, easily brings out reinfection simultaneously and dyes, and certain toxic and side effects is arranged.The Chinese medicine preparation that has is only paid attention to the part, takes into account with the part and ignore integral body, selects the specific aim of medicine single, has the uneasy congruent factor of medication, and from selecting medicine all can not guarantee the active ingredient of former medicine to technology, so do not reach the purpose for the treatment of both the principal and secondary aspects of a disease.As: a pair of agate beautiful jade, reduce if take the improper human leukocytes that makes, hepatic and renal function is impaired, and causes leukemia.
Summary of the invention
The object of the present invention is to provide psoriatic Chinese medicine preparation of a kind of treatment and preparation method thereof, it has solved background technology and has selected the specific aim of medicine single, and the technical problem of toxicity, side effect is arranged.
Technical solution of the present invention is:
The psoriatic Chinese medicine preparation of a kind of treatment, its special character is: this Chinese medicine preparation is formed by the feedstock production that comprises following consumption proportion
Radix Arnebiae (Radix Lithospermi) 10～50%, Radix Scutellariae or Rhizoma Coptidis 3～30%, Cortex Moutan or Radix Paeoniae Rubra 6～30%,
Radix Salviae Miltiorrhizae or Rhizoma Chuanxiong or Olibanum 6～40%, Radix Scrophulariae or Radix Rehmanniae 6～30%, Cortex Dictamni 4～40%,
Rhizoma Smilacis Glabrae or Herba Andrographis 4～45%, the Fructus Kochiae 5～20%, Zaocys or Agkistrodon 3～40%,
Radix Clematidis 6～40%, Radix Glycyrrhizae 2～15%.
Above-mentioned Chinese medicine preparation also can add the raw material of following consumption proportion:
Semen Platycladi or Radix Polygalae or Poria cum Radix Pini 5～30%.
Above-mentioned Chinese medicine preparation also can add the raw material of following consumption proportion:
Radix Sophorae Flavescentis 2～40%.
Above-mentioned Chinese medicine preparation is suitable for by the feedstock production that comprises following consumption proportion and forms
Radix Arnebiae (Radix Lithospermi) 14～30%, Radix Scutellariae or Rhizoma Coptidis 4～18%, Cortex Moutan or Radix Paeoniae Rubra 8～18%,
Radix Salviae Miltiorrhizae or Rhizoma Chuanxiong or Olibanum 6～18%, Radix Scrophulariae or Radix Rehmanniae 6～18%, Cortex Dictamni 5～20%,
Rhizoma Smilacis Glabrae or Herba Andrographis 5～25%, the Fructus Kochiae 5～16%, Zaocys or Agkistrodon 3～25%,
Radix Clematidis 8～25%, Radix Glycyrrhizae 2～10%, Semen Platycladi or Radix Polygalae or Poria cum Radix Pini 5～20%,
Radix Sophorae Flavescentis 2～15%.
Above-mentioned Chinese medicine preparation is with preferable by the feedstock production that comprises following consumption proportion
Radix Arnebiae (Radix Lithospermi) 18%, Radix Scutellariae or Rhizoma Coptidis 8%, Cortex Moutan or Radix Paeoniae Rubra 10%,
Radix Salviae Miltiorrhizae or Rhizoma Chuanxiong or Olibanum 10%, Radix Scrophulariae or Radix Rehmanniae 10%, Cortex Dictamni 8%,
Rhizoma Smilacis Glabrae or Herba Andrographis 5%, the Fructus Kochiae 6%, Zaocys or Agkistrodon 3%,
Radix Clematidis 8%, Radix Glycyrrhizae 4%, Semen Platycladi or Radix Polygalae or Poria cum Radix Pini 6%,
Radix Sophorae Flavescentis 4%.
In the raw material of above-mentioned Chinese medicine preparation:
Radix Scutellariae or Rhizoma Coptidis are the best to get Radix Scutellariae, and Rhizoma Coptidis takes second place;
Cortex Moutan or Radix Paeoniae Rubra are the best to get Cortex Moutan, and Radix Paeoniae Rubra takes second place;
Radix Salviae Miltiorrhizae or Rhizoma Chuanxiong or Olibanum are the best to get Radix Salviae Miltiorrhizae, and Rhizoma Chuanxiong is preferable, and Olibanum takes second place;
Radix Scrophulariae or Radix Rehmanniae are the best to get Radix Scrophulariae, and Radix Rehmanniae takes second place;
Rhizoma Smilacis Glabrae or Herba Andrographis are the best with the Poria that fetches earth, and Herba Andrographis takes second place;
Zaocys or Agkistrodon are the best to get Zaocys, and Agkistrodon takes second place;
Semen Platycladi or Radix Polygalae or Poria cum Radix Pini are the best to get Semen Platycladi, and Radix Polygalae is preferable, and Poria cum Radix Pini takes second place.
A kind of preparation method for the treatment of the psoriasis Chinese medicine preparation as mentioned above, its special character is: the operation of this preparation method comprises
1) gets Radix Salviae Miltiorrhizae, Cortex Moutan, section; In the alcohol reflux jar, extract, extract at least three times with 60% alcohol heating reflux; Filtrate merges, and gets medicinal liquid; Alcohol extraction medicinal residues device are in addition collected standby;
2) ethanol in the medicinal liquid is reclaimed, be concentrated into thick paste;
3) with thick paste at hothouse in dry below 60 ℃, the medicine piece;
4) the medicine piece is ground into fine powder, gets the alcohol extraction fine powder;
5) get Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Cortex Dictamni, Radix Sophorae Flavescentis, Rhizoma Smilacis Glabrae, the Fructus Kochiae, Zaocys, Radix Clematidis, Radix Scrophulariae, Semen Platycladi, Radix Glycyrrhizae, merge with above-mentioned alcohol extraction medicinal residues filtrate;
6) add water, decocting and concentrating cools;
7) in the alcohol reflux jar, add ethanol cold preservation sucking filtration, reclaim ethanol and be concentrated into thick paste, get the decocting ointment;
8) with the decocting ointment in dry below 65 ℃, pulverize, decocting medicated powder;
9) alcohol extraction fine powder and decocting medicated powder is even, drying must be synthesized medicated powder.
Above-mentioned preparation section also can comprise
Medicated powder be will synthesize and capsule, electuary, tablet, pill or oral liquid directly made; Maybe will synthesize medicated powder water or ethanol, be best with ethanol, makes granule.
The present invention has the following advantages:
1. the present invention selects medicine according to the cause of disease, is based on integral body, payes attention in the part, and treating both the principal and secondary aspects of a disease, strengthening vital QI to eliminate pathogenic factors, warming YANG collateral dredging, blood enriching and dryness moistening, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, dispelling wind for relieving itching are taken into account in whole and part;
2. has the outgrowth effect of the psoriasis epidermis of inhibition;
3. anti-inflammatory.Psoriasis is the struvite dermatosis of a kind of easy recurrence, and antiinflammatory action of the present invention can be eliminated this disease;
4. can improve blood rheology parameter, improve immune function of human body;
5. can effectively contain and the state of an illness prevent disease relapse;
6. the present invention has fully guaranteed the active ingredient of former medicine from selecting medicine to technology, and preparation technology is reasonable, and product is evident in efficacy.Not only volumes of formulation is dwindled, and pure dissolubility and water solublity active ingredient also can be fully used in the medical material.
7. have no side effect drug safety substantially.
The specific embodiment
Psoriatic morbidity main diseases is because of being that the diseases caused by exogenous pathogenic factor ailment said due to cold or exposure is fought in skin, and strongly fragrant heat-transformation of a specified duration so that pathogenic heat are gone into blood, cause heat in blood; The pathogenic heat retardance, blood operation is not smooth; Because the pathogenic heat consumption is hindered, part patient deficiency of both the liver and kidney, taste imbalance in addition, the nutrient blood discord causes deficiency of YIN-blood.The present invention adopts strengthening vital QI to eliminate pathogenic factors, the warming YANG collateral dredging, and blood enriching and dryness moistening, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, dispelling wind for relieving itching is at the cause of disease.
Chinese medicine preparation of the present invention is formed by the feedstock production of following consumption proportion
Radix Arnebiae (Radix Lithospermi) 10～50%, Radix Scutellariae or Rhizoma Coptidis 3～30%, Cortex Moutan or Radix Paeoniae Rubra 6～30%,
Radix Salviae Miltiorrhizae or Rhizoma Chuanxiong or Olibanum 6～40%, Radix Scrophulariae or Radix Rehmanniae 6～30%, Cortex Dictamni 4～40%,
Rhizoma Smilacis Glabrae or Herba Andrographis 4～45%, the Fructus Kochiae 5～20%, Zaocys or Agkistrodon 3～40%,
Radix Clematidis 6～40%, Radix Glycyrrhizae 2～15%.
The raw material that can add following consumption proportion in the Chinese medicine preparation of the present invention:
Semen Platycladi or Radix Polygalae or Poria cum Radix Pini 0～30%.
The raw material that also can add following consumption proportion in the Chinese medicine preparation of the present invention:
Radix Sophorae Flavescentis 0～40%.
Prepare the embodiment 1～18 of Chinese medicine preparation raw material consumption proportion of the present invention, its proportioning unit is weight percentage:
| Material name | Example 1 | Example 2 | Example 3 | Example 4 | Example 5 | Example 6 | Example 7 | Example 8 | Example 9 | Example 10 | Example 11 | Example 12 | Example 13 | Example 14 | Example 15 | Example 16 | Example 17 | Example 18 |
| Radix Arnebiae (Radix Lithospermi) | 50 | ?10 | ?16 | ?25 | ?35 | ?42 | ?10 | ?10 | ?10 | ?10 | ?10 | ?10 | ?10 | ?10 | ?10 | ?10 | ?10 | ?10 |
| Radix Scutellariae or Rhizoma Coptidis | 3 | ?30 | ?24 | ?7 | ?18 | ?10 | ?3 | ?3 | ?3 | ?3 | ?3 | ?3 | ?3 | ?3 | ?3 | ?3 | ?3 | ?3 |
| Cortex Moutan or Radix Paeoniae Rubra | 6 | ?10 | ?20 | ?30 | ?6 | ?6 | ?6 | ?6 | ?6 | ?6 | ?6 | ?6 | ?6 | ?14 | ?6 | ?6 | ?6 | ?6 |
| Radix Salviae Miltiorrhizae or Rhizoma Chuanxiong or Olibanum | 6 | ?6 | ?10 | ?6 | ?6 | ?6 | ?40 | ?20 | ?30 | ?6 | ?6 | ?6 | ?6 | ?6 | ?6 | ?6 | ?6 | ?6 |
| Radix Scrophulariae or Radix Rehmanniae | 6 | ?10 | ?6 | ?6 | ?6 | ?6 | ?17 | ?30 | ?6 | ?6 | ?6 | ?6 | ?6 | ?6 | ?6 | ?6 | ?6 | ?6 |
| Cortex Dictamni | 4 | ?10 | ?4 | ?4 | ?4 | ?4 | ?4 | ?4 | ?4 | ?40 | ?4 | ?21 | ?4 | ?4 | ?4 | ?4 | ?4 | ?4 |
| Rhizoma Smilacis Glabrae or Herba Andrographis | 4 | ?4 | ?4 | ?4 | ?4 | ?4 | ?4 | ?4 | ?4 | ?13 | ?45 | ?4 | ?4 | ?4 | ?24 | ?32 | ?9 | ?4 |
| The Fructus Kochiae | 5 | ?5 | ?5 | ?5 | ?5 | ?5 | ?5 | ?5 | ?5 | ?5 | ?9 | ?20 | ?5 | ?5 | ?5 | ?5 | ?15 | ?5 |
| Zaocys or Agkistrodon | 3 | ?5 | ?3 | ?3 | ?3 | ?3 | ?3 | ?3 | ?3 | ?3 | ?3 | ?3 | ?14 | ?40 | ?28 | ?3 | ?3 | ?8 |
| Radix Clematidis | 6 | ?6 | ?6 | ?6 | ?6 | ?12 | ?6 | ?6 | ?6 | ?6 | ?6 | ?6 | ?40 | ?6 | ?6 | ?23 | ?6 | ?6 |
| Radix Glycyrrhizae | 2 | ?2 | ?2 | ?4 | ?2 | ?2 | ?2 | ?9 | ?2 | ?2 | ?2 | ?15 | ?2 | ?2 | ?2 | ?2 | ?2 | ?2 |
| Semen Platycladi or Radix Polygalae or Poria cum Radix Pini | 5 | ?0 | ?0 | ?0 | ?0 | ?0 | ?0 | ?0 | ?16 | ?0 | ?0 | ?0 | ?0 | ?0 | ?0 | ?0 | ?0 | ?40 |
| Radix Sophorae Flavescentis | 0 | ?2 | ?0 | ?0 | ?5 | ?0 | ?0 | ?0 | ?5 | ?0 | ?0 | ?0 | ?0 | ?0 | ?0 | ?0 | ?30 | ?0 |
Preparation technology's Main Ingredients and Appearance of the present invention adopts alcohol reflux, water decoction-alcohol sedimentation.
To prepare the concrete operation of Chinese medicine preparation as follows for the raw material consumption proportion according to the present invention:
1. get Radix Salviae Miltiorrhizae, Cortex Moutan, section; In the alcohol reflux jar, extract, extract at least three times with 60% alcohol heating reflux; Filtrate merges, and gets medicinal liquid; Alcohol extraction medicinal residues device are in addition collected standby;
2. the ethanol in the medicinal liquid is reclaimed, be concentrated into thick paste;
With thick paste at hothouse in dry below 60 ℃, the medicine piece;
4. the medicine piece is ground into fine powder, gets the alcohol extraction fine powder;
5. get Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Cortex Dictamni, Radix Sophorae Flavescentis, Rhizoma Smilacis Glabrae, the Fructus Kochiae, Zaocys, Radix Clematidis, Radix Scrophulariae, Semen Platycladi, Radix Glycyrrhizae, merge with above-mentioned alcohol extraction medicinal residues filtrate;
6. add water, decocting and concentrating cools;
7. in the alcohol reflux jar, add ethanol cold preservation sucking filtration, reclaim ethanol and be concentrated into thick paste, get the decocting ointment;
With the decocting ointment in dry below 65 ℃, pulverize, decocting medicated powder;
9. with alcohol extraction fine powder and decocting medicated powder mix homogeneously, drying must be synthesized medicated powder;
10. synthetic medicated powder can directly be made capsule, electuary, tablet, pill or oral liquid; Synthetic medicated powder water or ethanol are best with ethanol, can be made into granule.
The raw material consumption proportion prepares in the concrete operation of Chinese medicine preparation according to the present invention, and the preparation of Radix Paeoniae Rubra can be with reference to Cortex Moutan; The preparation of Rhizoma Coptidis can be with reference to Radix Scutellariae; The preparation of Rhizoma Chuanxiong or Olibanum can be with reference to Radix Salviae Miltiorrhizae; The preparation of Radix Rehmanniae can be with reference to Radix Scrophulariae; The preparation of Herba Andrographis can be with reference to Rhizoma Smilacis Glabrae; The preparation of Agkistrodon can be with reference to Zaocys; Radix Polygalae or Poria cum Radix Pini's preparation can be with reference to Semen Platycladi.
The principles of formulating prescriptions are analyzed:
Psoriasis is mainly due to feelings will internal injury, and taste are become estranged, and outer wind-engaging, cold, worm, the evil invasion and attack of poison such as wet form, thus treatment by oral administration of medicines mainly with liver-smoothing, qi-regulating, the spleen and stomach regulating, cleaning blood, the dispersing wind-cold heresy is malicious, separates the damp and hot poison of blood system, promoting blood circulation to remove obstruction in the collateral, the skin moistening that nourishes blood is controlled it.Radix Arnebiae (Radix Lithospermi), Radix Scutellariae are monarch drug, heat-clearing and toxic substances removing; Cortex Moutan, Radix Salviae Miltiorrhizae, Radix Scrophulariae are ministerial drug, blood circulation promoting and blood stasis dispelling; Monarch drug and ministerial drug have the effect of pathogenic fire purging YIN nourishing, cooling blood and dissolving purpura concurrently.Adjuvant drug Cortex Dictamni, Radix Sophorae Flavescentis, Rhizoma Smilacis Glabrae, the Fructus Kochiae, Zaocys, Radix Clematidis are adjuvant drug, all can dispelling wind and removing obstruction in the collateral, clear away the dampness and heat, and can separate skin, sharp joint, killing parasites for relieving itching; Messenger drug Semen Platycladi, Radix Glycyrrhizae are messenger drug, and tying-in is gone into network and middle emergency, lung moistening intestinal, strengthening the spleen and stomach, nourishing blood to tranquillize the mind.
The present invention is through treating psoriasis with the Pilulae Indigo Naturalis contrast, and clinical test results is as follows:
1. statistical method analysis: all statistical test all adopt two-sided test, and the P value is less than or equal to 0.05 difference that will be considered to be checked statistical significance.Quantitative target adopts the elementary statistics describing method of quantitative target to be described, and calculates arithmetic mean, standard deviation, median, minima, maximum.Qualitative index is calculated routine number and the percent under the corresponding classification.The measurement data data, relatively, the person that meets the normal distribution is with t check between group between group, homogeneity test of variance unexpectedly, variance neat mutually person check with t, and the heterogeneity of variance person is with proofreading and correct t check (t ' check).The person that do not meet the normal distribution is with non-ginseng analysis.Counting and ranked data The data frequency (constituent ratio) are carried out descriptive statistics, relatively adopt rank test between the ranked data group.Enumeration data adopts X
2Check, or the definite probabilistic method check of Fisher.List statistic and definite P value.
2. the selected performance that reaches: sum up the selected and performance in various centers respectively, and sum up its corresponding statistical analysis crowd's situation.List the inventory of the case that comes off.
3. demography ordinary circumstance and disease baseline case: to sex, age bracket, course of disease section, the classification of the primary symptom integration state of an illness, the classification of erythra distribution, primary symptom scoring distribute (erythema, squama degree, soak into plump, pruritus degree), inferior disease distributes (vexed, thirsty or xerostomia, constipation, yellow urine), picture of the tongue, pulse condition, adopts X
2Routine number, percentage ratio, X are listed in check
2Value, definite P value; To age, the course of disease, body weight, height, adopt the t check, list average, standard deviation, median, minima, maximum, t statistic of test, definite P value; As do not meet normal distribution, adopt the nonparametric analysis.
4. clinical curative effect analysis:
1) Comprehensive Treatment, traditional Chinese medical science disease curative effect: calculate the routine number and the percentage rate of all kinds of curative effects, and employing compares to two groups by the stratified CMH-in center * 2 checks.
2) primary symptom individual event symptom curative effect: calculate the routine number and the percentage rate of all kinds of curative effects, and adopt rank test that two groups are compared.
3) inferior disease individual event symptom curative effect: list the disappearance rate of time each individual event symptom of disease, and adopt X 2 test that two groups are compared.
4) primary symptom total mark, erythra area scoring always: calculate mean, standard deviation, median, minima, the maximum of score value first, that last is made a house call and test front and back changing value, and adopt the t check to compare.Consider the effect of baseline, center, grouping, 95% credibility interval of calculating two groups of differences.In addition, for investigating the concordance at center, also match is contained center and the interactive covariance model of grouping, and judge whether to exist reciprocal action in 0.10 level.
5) drug combination: with drug combination by having, do not have tabulation, listing routine number, percentage ratio.And press medicine and number Verbose Listing.
5. safety evaluatio: divide the life sign, a situation arises for adverse events, safety experiment chamber index is added up respectively, to clinical meaning situation of change before and after the safety indexes medication adopt the test example number, just/just, just/different, different/just, differently/different, preceding lack, items such as the back lacks, front and back lack, disappearance subtotal add up, and list every routine number.And list and test the unusual person's inventory of safety indexes when finishing.
6. main statistical analysis conclusion:
Go into group and performance: A and organize, finish 310 examples into group 327 examples; B organizes into group 108 examples, finishes 97 examples.Add up to go into group 435 examples, finish 407 examples.
Demography and baseline: aspects such as sex, age, the course of disease, body weight, height, the classification of the primary symptom integration state of an illness, the classification of erythra distribution, primary symptom scoring distribute (erythema, squama degree, soak into plump, pruritus degree), inferior disease distributes (vexed, thirsty or xerostomia, constipation, yellow urine), picture of the tongue, pulse condition relatively, not statistically significant has comparability.
Comprehensive therapeutic effect, traditional Chinese medical science disease curative effect compare, and the A group has statistical significance with B group difference, and the A group is better than B and organizes.ITT, PP crowd's conclusion unanimity.Traditional Chinese medical science individual event symptom curative effect compares, erythema, squama degree, plump, the pruritus degree of infiltration, and the A group is organized difference with B statistical significance, and A organizes and is better than the B group.ITT, PP crowd's conclusion unanimity.The disappearance rate of two groups diseases is (ITT) relatively, not statistically significant.The main symptom total mark changes (ITT), and two groups relatively, and difference has statistical significance before and after 8 weeks and the treatment, and A group decline degree is organized greater than B; The scoring of erythra area changes (ITT), and two groups relatively, and difference has statistical significance before and after 8 weeks and the treatment, and A group decline degree is organized greater than B; Covariance analysis does not have cross effect between center and the grouping.Treat back tongue arteries and veins relatively (PP), not statistically significant.
Drug combination situation (ITT): A group 1 (0.3%).No change before and after two groups of vital sign tests.The adverse events incidence rate compares, A group 11/324 (3.4%); B group 5/106 (4.7%), two groups relatively, not statistically significant.Adverse events classification situation: symptom of digestive tract A group 8/324 (2.5%); B group 5/106 (4.7%), other A groups 3/324 (0.9%).Wherein, judge through the doctor, the adverse events relevant with medicine, A group 10/324, B group 5/106: with the irrelevant adverse events of medicine, A group 1/324.
Claims (7)
1. treat psoriatic Chinese medicine preparation for one kind, it is characterized in that: this Chinese medicine preparation is formed by the feedstock production that comprises following consumption proportion
Radix Arnebiae (Radix Lithospermi) 10～50%, Radix Scutellariae or Rhizoma Coptidis 3～30%, Cortex Moutan or Radix Paeoniae Rubra 6～30%,
Radix Salviae Miltiorrhizae or Rhizoma Chuanxiong or Olibanum 6～40%, Radix Scrophulariae or Radix Rehmanniae 6～30%, Cortex Dictamni 4～40%,
Rhizoma Smilacis Glabrae or Herba Andrographis 4～45%, the Fructus Kochiae 5～20%, Zaocys or Agkistrodon 3～40%,
Radix Clematidis 6～40%, Radix Glycyrrhizae 2～15%.
2. the psoriatic Chinese medicine preparation of treatment according to claim 1, it is characterized in that: described Chinese medicine preparation also comprises the raw material of following consumption proportion
Semen Platycladi or Radix Polygalae or Poria cum Radix Pini 5～30%.
3. the psoriatic Chinese medicine preparation of treatment according to claim 1 and 2, it is characterized in that: described Chinese medicine preparation also comprises the raw material of following consumption proportion
Radix Sophorae Flavescentis 2～40%.
4. the psoriatic Chinese medicine preparation of treatment according to claim 3, it is characterized in that: described Chinese medicine preparation is formed by the feedstock production that comprises following consumption proportion
Radix Arnebiae (Radix Lithospermi) 14～30%, Radix Scutellariae or Rhizoma Coptidis 4～18%, Cortex Moutan or Radix Paeoniae Rubra 8～18%,
Radix Salviae Miltiorrhizae or Rhizoma Chuanxiong or Olibanum 6～18%, Radix Scrophulariae or Radix Rehmanniae 6～18%, Cortex Dictamni 5～20%,
Rhizoma Smilacis Glabrae or Herba Andrographis 5～25%, the Fructus Kochiae 5～16%, Zaocys or Agkistrodon 3～25%,
Radix Clematidis 8～25%, Radix Glycyrrhizae 2～10%, Semen Platycladi or Radix Polygalae or Poria cum Radix Pini 5～20%,
Radix Sophorae Flavescentis 2～15%.
5. the psoriatic Chinese medicine preparation of treatment according to claim 4, it is characterized in that: described Chinese medicine preparation is formed by the feedstock production that comprises following consumption proportion
Radix Arnebiae (Radix Lithospermi) 18%, Radix Scutellariae or Rhizoma Coptidis 8%, Cortex Moutan or Radix Paeoniae Rubra 10%,
Radix Salviae Miltiorrhizae or Rhizoma Chuanxiong or Olibanum 10%, Radix Scrophulariae or Radix Rehmanniae 10%, Cortex Dictamni 8%,
Rhizoma Smilacis Glabrae or Herba Andrographis 5%, the Fructus Kochiae 6%, Zaocys or Agkistrodon 3%,
Radix Clematidis 8%, Radix Glycyrrhizae 4%, Semen Platycladi or Radix Polygalae or Poria cum Radix Pini 6%,
Radix Sophorae Flavescentis 4%.
6. preparation method according to the described treatment psoriasis of claim 1 Chinese medicine preparation, it is characterized in that: the operation of this preparation method comprises
1) gets Radix Salviae Miltiorrhizae, Cortex Moutan, section; In the alcohol reflux jar, extract, extract at least three times with 60% alcohol heating reflux; Filtrate merges, and gets medicinal liquid; Alcohol extraction medicinal residues device are in addition collected standby;
2) ethanol in the medicinal liquid is reclaimed, be concentrated into thick paste;
3) with thick paste at hothouse in dry below 60 ℃, the medicine piece;
4) the medicine piece is ground into fine powder, gets the alcohol extraction fine powder;
5) get Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Cortex Dictamni, Radix Sophorae Flavescentis, Rhizoma Smilacis Glabrae, the Fructus Kochiae, Zaocys, Radix Clematidis, Radix Scrophulariae, Semen Platycladi, Radix Glycyrrhizae, merge with above-mentioned alcohol extraction medicinal residues filtrate;
6) add water, decocting and concentrating cools;
7) in the alcohol reflux jar, add ethanol cold preservation sucking filtration, reclaim ethanol and be concentrated into thick paste, get the decocting ointment;
8) with the decocting ointment in dry below 65 ℃, pulverize, decocting medicated powder;
9) with alcohol extraction fine powder and decocting medicated powder mix homogeneously, drying must be synthesized medicated powder.
7. according to the preparation method of the described treatment psoriasis of claim 6 Chinese medicine preparation, it is characterized in that: the operation of this preparation method comprises
Medicated powder be will synthesize and capsule, electuary, tablet, pill or oral liquid directly made; Maybe will synthesize medicated powder water or ethanol and make granule.
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102078435A (en) * | 2010-12-25 | 2011-06-01 | 马建国 | Medicinal oil for treating pityriasis rosea and preparation method thereof |
| CN102716391A (en) * | 2012-06-15 | 2012-10-10 | 漳州片仔癀药业股份有限公司 | Pharmaceutical composite for treating skin itch |
| CN103341099A (en) * | 2013-07-10 | 2013-10-09 | 吴中区胥口精益生物医药研究所 | Traditional Chinese medicine essence for preventing and treating psoriasis, and extraction method thereof |
| CN103920113A (en) * | 2014-04-02 | 2014-07-16 | 王欣英 | Traditional Chinese medicine for treating psoriasis |
| CN104027672A (en) * | 2014-07-06 | 2014-09-10 | 华菊 | Traditional Chinese medicine composition for treating psoriasis |
| CN104524366A (en) * | 2014-12-15 | 2015-04-22 | 刘杰 | Traditional Chinese medicine composition for treating psoriasis |
| CN107661463A (en) * | 2017-06-15 | 2018-02-06 | 王益元 | A kind of medicine and its application method for treating psoriasis |
| CN110833583A (en) * | 2019-12-12 | 2020-02-25 | 亢跃进 | Traditional Chinese medicine for treating psoriasis and preparation method thereof |
| CN111743981A (en) * | 2020-08-06 | 2020-10-09 | 辽宁宝一堂科技发展有限公司 | Preparation method of cleaning liquid medicine for treating psoriasis |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1108810C (en) * | 1999-02-26 | 2003-05-21 | 魏鹏 | Medicine for treating psoriasis and preparing process thereof |
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2004
- 2004-08-27 CN CNB2004100730405A patent/CN100353970C/en not_active Expired - Fee Related
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102078435A (en) * | 2010-12-25 | 2011-06-01 | 马建国 | Medicinal oil for treating pityriasis rosea and preparation method thereof |
| CN102078435B (en) * | 2010-12-25 | 2012-09-05 | 马建国 | Medicinal oil for treating pityriasis rosea and preparation method thereof |
| CN102716391A (en) * | 2012-06-15 | 2012-10-10 | 漳州片仔癀药业股份有限公司 | Pharmaceutical composite for treating skin itch |
| CN103341099A (en) * | 2013-07-10 | 2013-10-09 | 吴中区胥口精益生物医药研究所 | Traditional Chinese medicine essence for preventing and treating psoriasis, and extraction method thereof |
| CN103920113A (en) * | 2014-04-02 | 2014-07-16 | 王欣英 | Traditional Chinese medicine for treating psoriasis |
| CN104027672A (en) * | 2014-07-06 | 2014-09-10 | 华菊 | Traditional Chinese medicine composition for treating psoriasis |
| CN104524366A (en) * | 2014-12-15 | 2015-04-22 | 刘杰 | Traditional Chinese medicine composition for treating psoriasis |
| CN107661463A (en) * | 2017-06-15 | 2018-02-06 | 王益元 | A kind of medicine and its application method for treating psoriasis |
| CN110833583A (en) * | 2019-12-12 | 2020-02-25 | 亢跃进 | Traditional Chinese medicine for treating psoriasis and preparation method thereof |
| CN111743981A (en) * | 2020-08-06 | 2020-10-09 | 辽宁宝一堂科技发展有限公司 | Preparation method of cleaning liquid medicine for treating psoriasis |
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| CN100353970C (en) | 2007-12-12 |
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