CN1732872A - Bidirectional digital modulating multi-channel artificial cochlea system - Google Patents

Bidirectional digital modulating multi-channel artificial cochlea system Download PDF

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CN1732872A
CN1732872A CN 200510012003 CN200510012003A CN1732872A CN 1732872 A CN1732872 A CN 1732872A CN 200510012003 CN200510012003 CN 200510012003 CN 200510012003 A CN200510012003 A CN 200510012003A CN 1732872 A CN1732872 A CN 1732872A
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CN100394903C (en
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张春
王志华
麦宋平
李冬梅
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Tsinghua University
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Tsinghua University
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Abstract

The invention relates to a bidirectional digital modulation multi-channel manual cochlear system, pertaining to the arts of electronic information technology and medical appliance. The system comprises external and internal circuits and electrodes. The external circuit is for collecting sound signal and sending to the internal circuit after enlarging, digitalizing and modulating in wireless way, at the same time, providing interface for programming and measuring the internal circuit. The internal circuit demodulates the received signal, and deals the demodulated data by the built-in digital signal-processing unit, to control the outlet of electrode assemblies, program on line or provide reversal results. The system integrates the low-power consumption digital signal-processing unit to the internal circuit, so the external circuit only sends narrow range sound signal, to cancel the width limitation of wireless transmission band, and improve the accuracy of dealing. Moreover, the system provides with remote updating.

Description

Bidirectional digital modulating multi-channel artificial cochlea system
Technical field
The present invention relates to a kind of bidirectional digital modulating multi-channel artificial cochlea system, belong to electronic information technology and medical instruments field.
Background technology
Medically be referred to as the threshold of audibility complete deafness the patient more than 90 decibels.The complete deafness reason of most of patient is the damage rather than the acous deterioration of hair cell.The artificial cochlea is a kind of medical electronics that is used for the treatment of the sensitivities deafness, its function is exactly to replace the hair cell of pathological changes to finish the conversion of sound-electricity, with the remaining acoustic nerve of the stimulating electrical signal that has acoustic information, make the patient produce real auditory perception, thereby reach the purpose of recovering patient's audition.The speech processor of current artificial cochlea system generally adopts the frequency decomposition algorithm, relies on extracorporeal circuit to finish the digitized of the sound signal of telecommunication, decompose and pass to the body internal circuit with wireless mode again after filtering is also encoded.Because electrode number is big, the stimulus frequency height, institute's data quantity transmitted is often very big, need take massive band width (usually in hundred KHz even MHz magnitude), under the limited situation of carrier frequency, must cause data precision deficiency and energy transmission efficiency low, and then influence the performance of system.
Summary of the invention
The present invention is directed to existing deficiency in the above-mentioned background technology, propose a kind of bidirectional digital modulating multi-channel artificial cochlea system of the integrated digital of circuit in vivo signal processor, to reach the purpose that improves system accuracy and reduce power consumption.Under current technical conditions, the digital signal processor of integrated small size, extremely low power dissipation has become possibility in the circuit in vivo.The integrated digital signal processor can move to the decomposition filtering of voice signal and other relevant treatment tasks in the body and finishes in the circuit in vivo, make extracorporeal circuit only need to very narrow (several KHz~tens KHz of body internal circuit transmission bandwidth, the contrast aforementioned system hundreds of KHz even a few MHz) the compressed digital voice signal, at first eliminate the limited problem of transmission bandwidth, improved data processing precision in the body; Next has improved energy transmission efficiency, has reduced system power dissipation.
The bidirectional digital modulating multi-channel artificial cochlea system that the present invention proposes comprises extracorporeal circuit, the body internal circuit of mutual wireless coupling and the electrode group that links to each other with the body internal circuit:
(1) described extracorporeal circuit comprises sound collection unit, automatic gain control unit, digital to analog converter, Operations Analysis, computer interface unit, manipulator, comparator and external antenna, wherein,
Sound collection unit is made up of two mikes, and this sound collection unit is used to gather two-way voice or one road voice and one tunnel noise signal;
Automatic gain control unit is made up of two automatic gain control circuits, and its input links to each other with the outfan of above-mentioned two mikes respectively, and this automatic gain control unit is used to adjust the dynamic range of tut collecting unit output signal;
Analog-digital converter, form by an A/D changer, its two-way input end of analog signal links to each other with the outfan of above-mentioned two automatic gain control circuits respectively, and this A/D changer is used for the analog signal conversion of above-mentioned two automatic gain control circuits output is become digital signal;
Operations Analysis is made of gate circuit, and its input links to each other with the digital signal output end of above-mentioned A/D changer, and this arithmetic control circuit is used for the digital audio signal of above-mentioned A/D changer output is carried out compressed encoding and extracorporeal circuit is implemented control;
Computer interface unit is used for being connected of described system and computer;
Manipulator, constitute by transistor and Resistor-Capacitor Unit, an input of this manipulator links to each other with an outfan of above-mentioned Operations Analysis, another input links to each other with the outfan of aforementioned calculation machine interface unit, on the CF signal that described manipulator is used for the digital audio signal behind the coding or computer instruction are modulated to setting and carry out power amplification;
Comparator, its input links to each other with the voltage signal output end of said modulator, its outfan links to each other with the input of computer interface unit, and this comparator is used for when reverse the measurement manipulator voltage signal of exporting and the magnitude of voltage that presets being compared and comparative result being fed back to computer;
External antenna, its input links to each other with the modulation signal outfan of said modulator, and this external antenna is used for sending modulated signal to the body internal circuit;
(2) described body internal circuit comprises internal antenna, rectification filtering unit, demodulator, digital signal processor, reverse data output unit, digital to analog converter, voltage-controlled current source group and switch matrix, this body internal circuit is that above-mentioned each circuit unit is integrated in characteristic size is that the area that customizes under the technology of 0.18um is on the special chip of 3.5mm * 3.5mm, wherein
Internal antenna is coupled with above-mentioned external antenna, is used to receive the modulation signal that extracorporeal circuit sends over;
Rectification filtering unit, its input links to each other with the outfan of above-mentioned internal antenna, and this rectification filtering unit is used for the modulation signal that receives is carried out extracting the supply voltage of crest voltage as other circuit units in the body behind the rectifying and wave-filtering;
Demodulator, its modulation signal input links to each other with the outfan of above-mentioned internal antenna, and its voltage input end links to each other with the outfan of above-mentioned rectification filtering unit, and this demodulator is used for the modulation signal that receives is carried out extracting clock and data signal after the demodulation;
Digital signal processor, its clock links to each other with the outfan of above-mentioned demodulator with the data signal input, its voltage input end links to each other with the outfan of above-mentioned rectification filtering unit, this digital signal processor is used for the voice data or the computer instruction of above-mentioned demodulator output are handled: for acoustical signal, this digital signal processor carries out data decode to it, signal filtering, resonance point extract and frequency decomposition after according to the output of result control electrode, for programming instruction, this digital signal processor then enters programming state automatically and the routine data that receives is deposited in inner command memory, for measuring instruction, this digital signal processor is then realized the reverse data measuring operation;
The reverse data output unit, its data input pin links to each other with the outfan of above-mentioned digital signal processor, its voltage input end links to each other with the outfan of above-mentioned rectification filtering unit, its outfan links to each other with above-mentioned antenna, this reverse data output unit is used for the pulse that the size of the reverse measurement data that provides according to above-mentioned digital signal processor is exported respective width, and change antenna load as switch with pulse, to the reverse measurement data of extracorporeal circuit transmission;
Digital to analog converter is made of a D/A changer, and its input links to each other with the outfan of above-mentioned digital signal processor, and this D/A changer is used for converting the digital signal of digital signal processor output to analog voltage amount;
The voltage-controlled current source group, its input links to each other with the outfan of above-mentioned digital to analog converter, and this voltage-controlled current source group is used for the voltage of above-mentioned digital to analog converter output is changed into the current value of corresponding size;
Switch matrix, its input links to each other with the outfan of above-mentioned voltage-controlled current source group, its control end links to each other with the outfan of above-mentioned digital signal processor, and described switch matrix is used for the electrode channel that gating will be implemented to stimulate under the control of above-mentioned digital signal processor and exports stimulating current on respective channel;
(3) described electrode group, constitute by one group of silicone rubber electrode that applies with the polytetrafluoroethylene insulating coating, its input links to each other with the switch matrix of above-mentioned body internal circuit, its outfan directly links to each other with acoustic nerve, and this electrode group is used for the output current on the above-mentioned switch matrix respective channel is connected to stimulates acoustic nerve on the acoustic nerve.
The bidirectional digital modulating multi-channel artificial cochlea system that the present invention proposes, the digital signal processor by integrated small volume low watt consumption on the circuit in vivo makes system have data-handling capacity in the powerful body.Extracorporeal circuit only needs to transmit undressed pure narrow-band digital voice signal to the body internal circuit thus, has both improved the precision of system, has reduced the energy loss in the wireless transmission process again.This system voice signals sampling rate is more than 8K * 12bit/s, the total SR of the pulse of electrode is more than 1MHz, total power consumption is at (body internal circuit power consumption is below 8mW) below the 18mW, the extracorporeal circuit cumulative volume is at 48mm * 32mm * below the 10mm, shortage in weight 200g, chip area is below 3.5mm * 3.5mm in the body, whole system have the precision height, low in energy consumption, volume is little and advantage such as in light weight.In addition, intravital digital signal processor can also load multiple speech processing algorithm, and can add new speech processing algorithm at any time by the remote online programming.
Description of drawings
Fig. 1 is that system architecture diagram of the present invention: a is the extracorporeal circuit structured flowchart; B is a body interior circuit construction block diagram.
The specific embodiment
The bidirectional digital modulating multi-channel artificial cochlea system that the present invention proposes, its structured flowchart are respectively as depicted in figs. 1 and 2.Its extracorporeal circuit comprises: sound collection unit, automatic gain control unit, digital to analog converter, Operations Analysis, computer interface unit, manipulator, comparator and external antenna; The body internal circuit comprises: internal antenna, rectification filtering unit, demodulator, digital signal processor, reverse data output unit, digital to analog converter, voltage-controlled current source group and switch matrix; The body internal circuit links to each other with acoustic nerve by the electrode group.
The operation principle of system is as described below.Under the normal operating conditions, the sound collection unit of extracorporeal circuit at first converts tones into analog electrical signal, automatic gain control unit amplifies it, carry out suitable compression and coding through after the digital to analog conversion digitized acoustical signal being sent into operation processing unit, the digital audio signal of handling well is exported to antenna by modulators modulate again; Under programming or the measurement state, what manipulator was imported then is the instruction data, is provided by computer interface unit by computer, and comparator then detects the output voltage of manipulator to obtain reverse measurement data.The signal that internal antenna is received is at first delivered to rectification filtering unit and is extracted the required supply voltage of body internal circuit work, meanwhile modulation signal is carried out clock and data signal that demodulation obtains and all give digital signal processor, digital signal processor is handled accordingly to data of different types: for voice data, need finish data decode, signal filtering, computings such as resonance point extraction and frequency decomposition, result is sent to and converts aanalogvoltage on the digital to analog converter to, convert electric current to by the voltage-controlled current source group then, switch matrix is received electric current under the control of digital signal processor stimulates acoustic nerve on the corresponding electrode; For programming instruction, digital signal processor then enters programming state automatically, and the routine data that receives is deposited in the inner program storage; For measuring instruction, then measurement result is delivered to the reverse data output unit, change antenna load by this unit measurement data is passed to extracorporeal circuit.
Among the embodiment of this scheme, the model of mike is EM-100B in the sound collection unit, the model of automatic gain control unit is MAX4252, the model of analog-digital converter is MAX1287, the model of comparator is MAX987, Operations Analysis is made of simple gate circuit, manipulator then is made of transistor and Resistor-Capacitor Unit, computer interface adopts RS-232 interface, antenna is made of a pair of inductance coil, it is that the area that customizes under the 0.18um technology is on the special chip of 3.5mm * 3.5mm that the body internal circuit all is integrated in characteristic size, and the electrode group is made of 17 silicone rubber electrodes that apply with the polytetrafluoroethylene insulating coating.Whole system adopts complete 3.6 volts of power supplys design, with one 3.6 volts lithium rechargeable batteries or three joint Ni-MH battery power supplies, uses low pressure difference linear voltage regulator output 3.3V and 1.8V running voltage.Body internal circuit and electrode group are implanted patient's cochlea, and external antenna places the patient to be coupled with internal antenna in one's ear, and extracorporeal circuit (except that antenna) then is encapsulated in size in the box of 48mm * 32mm * 10mm, and link to each other with external antenna by lead.The patient can carry box-packed extracorporeal circuit, and can place any position of health.

Claims (1)

1, a kind of bidirectional digital modulating multi-channel artificial cochlea system is characterized in that this system comprises extracorporeal circuit, the body internal circuit of mutual wireless coupling and the electrode group that links to each other with the body internal circuit:
(1) described extracorporeal circuit comprises sound collection unit, automatic gain control unit, digital to analog converter, Operations Analysis, computer interface unit, manipulator, comparator and external antenna, wherein,
Sound collection unit is made up of two mikes, and this sound collection unit is used to gather two-way voice or one road voice and one tunnel noise signal;
Automatic gain control unit is made up of two automatic gain control circuits, and its input links to each other with the outfan of above-mentioned two mikes respectively, and this automatic gain control unit is used to adjust the dynamic range of tut collecting unit output signal;
Analog-digital converter, form by an A/D changer, its two-way input end of analog signal links to each other with the outfan of above-mentioned two automatic gain control circuits respectively, and this A/D changer is used for the analog signal conversion of above-mentioned two automatic gain control circuits output is become digital signal;
Operations Analysis is made of gate circuit, and its input links to each other with the digital signal output end of above-mentioned A/D changer, and this arithmetic control circuit is used for the digital audio signal of above-mentioned A/D changer output is carried out compressed encoding and extracorporeal circuit is implemented control;
Computer interface unit is used for being connected of described system and computer;
Manipulator, constitute by transistor and Resistor-Capacitor Unit, an input of this manipulator links to each other with an outfan of above-mentioned Operations Analysis, another input links to each other with the outfan of aforementioned calculation machine interface unit, on the CF signal that described manipulator is used for the digital audio signal behind the coding or computer instruction are modulated to setting and carry out power amplification;
Comparator, its input links to each other with the voltage signal output end of said modulator, its outfan links to each other with the input of computer interface unit, and this comparator is used for when reverse the measurement manipulator voltage signal of exporting and the magnitude of voltage that presets being compared and comparative result being fed back to computer;
External antenna, its input links to each other with the modulation signal outfan of said modulator, and this external antenna is used for sending modulated signal to the body internal circuit;
(2) described body internal circuit comprises internal antenna, rectification filtering unit, demodulator, digital signal processor, reverse data output unit, digital to analog converter, voltage-controlled current source group and switch matrix, this body internal circuit is that above-mentioned each circuit unit is integrated in characteristic size is that the area that customizes under the technology of 0.18um is on the special chip of 3.5mm * 3.5mm, wherein
Internal antenna is coupled with above-mentioned external antenna, is used to receive the modulation signal that extracorporeal circuit sends over;
Rectification filtering unit, its input links to each other with the outfan of above-mentioned internal antenna, and this rectification filtering unit is used for the modulation signal that receives is carried out extracting the supply voltage of crest voltage as other circuit units in the body behind the rectifying and wave-filtering;
Demodulator, its modulation signal input links to each other with the outfan of above-mentioned internal antenna, and its voltage input end links to each other with the outfan of above-mentioned rectification filtering unit, and this demodulator is used for the modulation signal that receives is carried out extracting clock and data signal after the demodulation;
Digital signal processor, its clock links to each other with the outfan of above-mentioned demodulator with the data signal input, its voltage input end links to each other with the outfan of above-mentioned rectification filtering unit, this digital signal processor is used for the voice data or the computer instruction of above-mentioned demodulator output are handled: for acoustical signal, this digital signal processor carries out data decode to it, signal filtering, resonance point extract and frequency decomposition after according to the output of result control electrode, for programming instruction, this digital signal processor then enters programming state automatically and the routine data that receives is deposited in inner command memory, for measuring instruction, this digital signal processor is then realized the reverse data measuring operation;
The reverse data output unit, its data input pin links to each other with the outfan of above-mentioned digital signal processor, its voltage input end links to each other with the outfan of above-mentioned rectification filtering unit, its outfan links to each other with above-mentioned antenna, this reverse data output unit is used for the pulse that the size of the reverse measurement data that provides according to above-mentioned digital signal processor is exported respective width, and change antenna load as switch with pulse, to the reverse measurement data of extracorporeal circuit transmission;
Digital to analog converter is made of a D/A changer, and its input links to each other with the outfan of above-mentioned digital signal processor, and this D/A changer is used for converting the digital signal of digital signal processor output to analog voltage amount;
The voltage-controlled current source group, its input links to each other with the outfan of above-mentioned digital to analog converter, and this voltage-controlled current source group is used for the voltage of above-mentioned digital to analog converter output is changed into the current value of corresponding size;
Switch matrix, its input links to each other with the outfan of above-mentioned voltage-controlled current source group, its control end links to each other with the outfan of above-mentioned digital signal processor, and described switch matrix is used for the electrode channel that gating will be implemented to stimulate under the control of above-mentioned digital signal processor and exports stimulating current on respective channel;
(3) described electrode group, constitute by one group of silicone rubber electrode that applies with the polytetrafluoroethylene insulating coating, its input links to each other with the switch matrix of above-mentioned body internal circuit, its outfan directly links to each other with acoustic nerve, and this electrode group is used for the output current on the above-mentioned switch matrix respective channel is connected to stimulates acoustic nerve on the acoustic nerve.
CNB2005100120038A 2005-06-24 2005-06-24 Bidirectional digital modulating multi-channel artificial cochlea system Expired - Fee Related CN100394903C (en)

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CN101926693A (en) * 2010-08-31 2010-12-29 重庆大学 Multi-channel light stimulation-based cochlear implant device
CN101347367B (en) * 2007-07-17 2011-02-16 美国诺尔康神经电子科技有限公司 Electronic cochlea utilizing multiple-resolution current sources and flexible data encoding plans
CN101653386B (en) * 2008-12-23 2011-05-11 深圳先进技术研究院 Electronic cochlea for realizing various physiological information detection functions
CN102133144A (en) * 2011-04-21 2011-07-27 清华大学深圳研究生院 Artificial cochlea system
CN103340704A (en) * 2013-07-26 2013-10-09 清华大学 In-vivo system of electrical cochlea debugging platform
CN103705229A (en) * 2012-09-29 2014-04-09 中国科学院声学研究所 Method and system for testing ECAP (equal-channel angular pressing) signals in cochlea
WO2014101156A1 (en) * 2012-12-31 2014-07-03 Spreadtrum Communications (Shanghai) Co., Ltd. Adaptive audio capturing
CN110850773A (en) * 2019-11-14 2020-02-28 北京和利时系统工程有限公司 Signal acquisition method and device, computer storage medium and electronic equipment

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CN101862228B (en) * 2010-06-13 2013-04-24 杭州诺尔康神经电子科技有限公司 Artificial cochlea
CN101862229B (en) * 2010-06-13 2013-06-12 杭州诺尔康神经电子科技有限公司 Artificial cochlea

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DE10018334C1 (en) * 2000-04-13 2002-02-28 Implex Hear Tech Ag At least partially implantable system for the rehabilitation of a hearing impairment
CN2522053Y (en) * 2001-07-19 2002-11-27 王晶 External-duct type micro artificial electronic cochlea
CN100486360C (en) * 2004-03-12 2009-05-06 梁华伟 Digital multi-channel voice processor for artificial cochlea
CN1600285A (en) * 2004-10-15 2005-03-30 清华大学 Dedicated IC chip for digital type electronic artificial ear

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101347367B (en) * 2007-07-17 2011-02-16 美国诺尔康神经电子科技有限公司 Electronic cochlea utilizing multiple-resolution current sources and flexible data encoding plans
CN101653386B (en) * 2008-12-23 2011-05-11 深圳先进技术研究院 Electronic cochlea for realizing various physiological information detection functions
CN101926693A (en) * 2010-08-31 2010-12-29 重庆大学 Multi-channel light stimulation-based cochlear implant device
CN102133144A (en) * 2011-04-21 2011-07-27 清华大学深圳研究生院 Artificial cochlea system
CN102133144B (en) * 2011-04-21 2013-03-13 清华大学深圳研究生院 Artificial cochlea system
CN103705229A (en) * 2012-09-29 2014-04-09 中国科学院声学研究所 Method and system for testing ECAP (equal-channel angular pressing) signals in cochlea
WO2014101156A1 (en) * 2012-12-31 2014-07-03 Spreadtrum Communications (Shanghai) Co., Ltd. Adaptive audio capturing
US9692379B2 (en) 2012-12-31 2017-06-27 Spreadtrum Communications (Shanghai) Co., Ltd. Adaptive audio capturing
CN103340704A (en) * 2013-07-26 2013-10-09 清华大学 In-vivo system of electrical cochlea debugging platform
CN103340704B (en) * 2013-07-26 2015-04-22 清华大学 In-vivo system of electrical cochlea debugging platform
CN110850773A (en) * 2019-11-14 2020-02-28 北京和利时系统工程有限公司 Signal acquisition method and device, computer storage medium and electronic equipment

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