CN1724004A - The health care medicine of prevention and treatment diabetic complication - Google Patents

The health care medicine of prevention and treatment diabetic complication Download PDF

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Publication number
CN1724004A
CN1724004A CN 200510012570 CN200510012570A CN1724004A CN 1724004 A CN1724004 A CN 1724004A CN 200510012570 CN200510012570 CN 200510012570 CN 200510012570 A CN200510012570 A CN 200510012570A CN 1724004 A CN1724004 A CN 1724004A
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radix
parts
folium
prevention
health care
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CN 200510012570
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CN1287818C (en
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成根杰
牛西午
吕慧卿
张克强
王兴华
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KAOLIANG INST SHANXI PROV ACADEMY OF AGRICULTURAL SCIENCES
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KAOLIANG INST SHANXI PROV ACADEMY OF AGRICULTURAL SCIENCES
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Abstract

The health care medicine of a kind of prevention and treatment diabetic complication relates to a kind of health care medicine.It is made up of Folium Mori, Folium Ginkgo, Fructus Mori, Radix Et Rhizoma Fagopyri Tatarici, Radix Notoginseng, Semen Cassiae.Solved the overwhelming majority that exists in the existing treatment diabetes method still with long term injections insulin or orally-taken blood sugar reducing medicine or the orally-taken blood sugar reducing medicine is kept the normal concentration of insulin in the blood and by the amount of control food and the problem of the harm that kind alleviates complication.The present invention can suppress the absorption of blood sugar increasing and cholesterol, reduces serum fat.Suppress thrombosis, the prevention of arterial sclerosis.Can promote the synthetic and excreting insulin of pancreatic, strengthen islet function.Promote sugar utilization, improve carbohydrate metabolism.Reach prevent diabetes generation, prevent and treat the purpose of complication.

Description

The health care medicine of prevention and treatment diabetic complication
Technical field
The present invention relates to a kind of health care medicine, specifically is the health care medicine of a kind of prevention and treatment diabetic complication.
Background technology
Diabetes be a kind of be the endocrine metabolism disease of feature with sugar, fat and protein metabolism disorder.The topmost pathological change of diabetes is: the distortion of pancreas beta Cell of islet, necrosis---the β cytoactive reduces, and quantity reduces---the corresponding minimizing of amount of insulin secretion---and occurs high sugar content in the blood.The factor of diabetes-induced has obesity, diet, age, physical exertion, emergent factor etc.Particularly bad dietary habit, as the food of the higher fatty acid high sugar of taking food is excessive.Especially for a long time be staple food with the smart powder of polished rice, cause the absorption of trace element and vitamin to lack.Because some trace element as: zinc, magnesium, chromium etc. play a part crucial in the synthetic and glucose metabolism of insulin.The overwhelming majority is still kept the normal concentration of insulin in the blood in the existing treatment diabetes method with long term injections insulin or orally-taken blood sugar reducing medicine or orally-taken blood sugar reducing medicine.But used of a specified duration and can produce antibody, caused biological activity to reduce, dosage increases generation and the development that the generation hyperinsulinemia can be impelled microangiopathies again.From the diet conservancy angle, mainly be at present amount and kind from control food, as anorexia high food of sugar content such as the smart face of polished rice etc., and high-fat food.The long-term control diet can cause malnutrition, the hypoglycemia phenomenon occurs, has more increased the weight of complication.
Summary of the invention
The present invention controls improper meeting and increases the weight of the problem of complication and a kind of novel prevention and the health care medicine of treatment diabetic complication are provided for the need that solve prior art and exist in prevent diabetes and the complication that caused by diabetes of treatment rely on insulin injection and diet for a long time.
The health care medicine of prevention of the present invention and treatment diabetic complication is made up of Folium Mori, Folium Ginkgo, Fructus Mori, Radix Et Rhizoma Fagopyri Tatarici, Radix Notoginseng, Semen Cassiae, and wherein the weight proportion of each component is:
50~80 parts on Folium Mori, 50~80 parts of Folium Ginkgos, 20~50 parts in Fructus Mori,
40~65 parts of Radix Et Rhizoma Fagopyri Tatarici, 25~50 parts of Radix Notoginseng, 40~60 parts of Semen Cassiaes.
The health care medicine of prevention of the present invention and treatment diabetic complication is made up of Folium Mori, Folium Ginkgo, Fructus Mori, Radix Et Rhizoma Fagopyri Tatarici, Radix Notoginseng, Semen Cassiae, and wherein the optimum weight proportioning of each component is:
55 parts on Folium Mori, 60 parts of Folium Ginkgos, 30 parts in Fructus Mori,
50 parts of Radix Et Rhizoma Fagopyri Tatarici, 25 parts of Radix Notoginseng, 50 parts of Semen Cassiaes.
Production method is as follows:
Earlier with exsiccant Folium Mori, Folium Ginkgo, Radix Et Rhizoma Fagopyri Tatarici pulverize separately to 120 order fine powder; Again Fructus Mori is cooked the airing post-treatment and be crushed to 120 order fineness; Pulverize separately was processed into 120 order fineness after other got Radix Notoginseng, Semen Cassiae drying, after above-mentioned whole powder are sieved by affiliated formula proportion mixing, made powder, or incapsulated.
Selected various medicines are based on motherland's medical science about diabetes and the pathogenetic understanding of complication thereof among the present invention, and according to Chinese medicine health preserving theory, in conjunction with pharmacological testing and zooperal result of study science are selected for use, prepared both at home and abroad.Each selected among the present invention component effect is as follows:
Folium Mori contain alkaloid 1-deoxynojirimycin (DNJ), Mulberry polyphenol, Folium Mori total polysaccharides (TMP), superoxide dismutase (SOD), reach multivitamin and trace element.The energy blood sugar control enters quantity and the speed in the blood, and blood sugar regulation improves anti-sugar amount, strengthens islet function, promotes islet cells to synthesize and excreting insulin.Improve carbohydrate metabolism, increase the utilization of cell, improve body immune function, alleviate or reduce the generation of complication sugar.Semen Ginkgo contains trace element such as compositions such as leaf flavone, bilobalide and tea polyphenols and selenium, zinc, copper, astringes the lung, and relievings asthma pain relieving.Through test arteries there is dilating effect, and can the hypercholesterolemia effect be arranged in addition the vasoconstriction effect due to the antiadrenergic drug.Clinical being used for: angina pectoris, myocardial infarction, arteriosclerotic peripheral vessels circulatory disturbance, cerebral embolism and cerebral vasospasm, hypertension etc.Improve blood flow, increase cerebral blood supply; Blood lipid regulation, to improve blood thick; The anti-cardiovascular disease defying age is eliminated human free radical; Blood pressure regulation.More than two kinds of components on the main curative effect of the health care medicine of realizing prevention of the present invention and treatment diabetic complication, particularly play a part in the treatment at complication crucial.
Fructus Mori contains compositions such as sugar, tannic acid, malic acid and vitamin B1, B2, C and carotene; The fatty acid of Fructus Mori oil mainly contains linoleic acid and a spot of stearic acid.Main function, tonifying liver, kidney tonifying, the treating the liver kidney yin is lost; Double treating constipation, order is dark, tinnitus, diseases such as articular instability.Radix Et Rhizoma Fagopyri Tatarici is rich in compositions such as globulariacitrin, cures mainly stomachache, dyspepsia, dysentery, impairment caused by overstrain, diseases such as lumbago and skelalgia.Semen Cassiae has liver heat removing and eyesight improving, and the function of diuretic relieving constipation cures mainly the wind heat acute conjunctivitis, nyctalopia, hypertension, hepatitis, liver cirrhosis, diseases such as habitual constipation.Radix Notoginseng has regulating action to blood circulation, can reduce the permeability of blood capillary, increases the resistance of blood capillary.These four kinds of components on the main curative effect of the health care medicine of realizing prevention of the present invention and treatment diabetic complication particularly the treatment at complication play auxiliary effect.
The health care medicine blood sugar regulation mechanism of prevention of the present invention and treatment diabetic complication mainly is by contained alkaloid 1-deoxynojirimycin (DNJ), Mulberry polyphenol (fagaomine) Folium Mori total polysaccharidess (TPM), superoxide dismutase (SOD), r-aminobutyric acid (GABA), flavone compound, plant sterol, mineral, and all multifunctional agentses such as dietary fiber, vitamin, trace element mutually combine, mutually promote, combined effect.Can suppress the absorption of blood sugar increasing and cholesterol.Suppress the cancerous protuberance development, protection biomembrane and hemoglobin exempt from damage.The formation, the reduction serum fat that suppress the body fat liver.Suppress thrombosis, the prevention of arterial sclerosis.Can promote the synthetic and excreting insulin of pancreatic, strengthen islet function.Promote sugar utilization, improve carbohydrate metabolism, reduce the absorption of sugar, strengthen the synthetic of hepatic glycogen.Enhance metabolism, the soft stool diuresis improves intestinal function, acceleration feces is discharged, remove harmful poisonous substance in the body, remove free radical, improve immunity, strengthen premunition, have the blood circulation of maintenance health, keep digestion, Excretory system health, improve health, improve life quality, reach prevent diabetes generation, prevent and treat complication.
Another characteristics of health medicine of the present invention are nutritious, can replenish the various nutrients that patient body lacked effectively, improve body immunity.Crude protein content is 19.65%, calcium 2%, magnesium 0.65%, phosphorus 0.27%, flavone compound 1.51%, fat 6.12%, crude fibre 56.26%, VE2.39mg/100g, ferrum 445.5mg/kg, zinc 30.63mg/kg.Amino acid content is 14.06%.Wherein: lysine 0.89%, arginase 12 .07%, leucine 1.18%, aspartic acid 1.16%, threonine 0.6%, serine 0.55%, glutamic acid 2.1%, proline 0.35%, glycine 0.77%, alanine 0.78%, cystine 0.11%, valine 0.92%, methionine 0.05%, isoleucine 0.68%, tyrosine 0.42%, phenylamino acid 0.76%, glycine 0.22%, histidine 0.27%.
By to 100 different medical histories, all ages and classes, observe (30 days course of treatment behind the diabetics oral test of the different state of an illness, every day 3 times, each 4-6 grain) display effect is remarkable as a result, particularly in control with alleviate good effect is arranged aspect the complication that causes by diabetes:
1,, keep blood glucose invariance degree effect obvious to blood sugar regulation.
2, to neuropathy, the blurred vision sx reaches 80%, insomnia 80%, and the skin pruritus symptom alleviates and reaches 70%, and the oral ulcer symptom reaches 85%.
3. to the intestinal pathological changes, the soft stool diuresis improves intestinal function, promotes enterokinesia, quickens feces and discharges, and removes the interior noxious substance effect of body and reaches 90%.
The accompanying drawing table:
Model case:
Zhao XX, the man, 65 years old, suffered from diabetes 20 years, by insulin injection treatment 18 years, the hypoglycemia phenomenon often took place in unsatisfactory curative effect, stupor occurred, shock.It is comparatively stable to take in the capsule that the present invention makes 100 days blood sugar level, simultaneously symptoms such as oral ulcer, skin pruritus, dry stool, constipation be improved significantly.
Guo XX, the man, 56 years old, suffer from diabetes for many years, and diseases such as blurred vision, numb hand and foot occur, long-term psychentonia, insomnia is being taken this health medicine after course of treatment, and symptom is obviously improved, and complication alleviates, and sleep quality improves, and spirit takes a turn for the better.
The specific embodiment
Embodiment 1: get Folium Mori 50 grams, Folium Ginkgo 50 grams, Fructus Mori 20 grams, Radix Et Rhizoma Fagopyri Tatarici 40 grams, Radix Notoginseng 25 grams, Semen Cassiae 40 grams respectively, earlier with exsiccant Folium Mori, Folium Ginkgo, Radix Et Rhizoma Fagopyri Tatarici pulverize separately to 120 order fine powder; Again Fructus Mori is cooked the airing post-treatment and be crushed to 120 order fineness; Pulverize separately was processed into 120 order fineness after other got Radix Notoginseng, Semen Cassiae drying, after above-mentioned whole powder are sieved by affiliated formula proportion mixing, made powder, or incapsulated.Every day 3 times, each 4-6 grain.
Embodiment 2: get Folium Mori 60 grams, Folium Ginkgo 55 grams, Fructus Mori 25 grams, Radix Et Rhizoma Fagopyri Tatarici 45 grams, Radix Notoginseng 30 grams, Semen Cassiae 45 grams respectively, earlier with exsiccant Folium Mori, Folium Ginkgo, Radix Et Rhizoma Fagopyri Tatarici pulverize separately to 120 order fine powder; Again Fructus Mori is cooked the airing post-treatment and be crushed to 120 order fineness; Pulverize separately was processed into 120 order fineness after other got Radix Notoginseng, Semen Cassiae drying, after above-mentioned whole powder are sieved by affiliated formula proportion mixing, made powder, or incapsulated.Every day 3 times, each 4-6 grain.
Embodiment 3: get Folium Mori 60 grams, Folium Ginkgo 55 grams, Fructus Mori 30 grams, Radix Et Rhizoma Fagopyri Tatarici 50 grams, Radix Notoginseng 30 grams, Semen Cassiae 40 grams respectively, earlier with exsiccant Folium Mori, Folium Ginkgo, Radix Et Rhizoma Fagopyri Tatarici pulverize separately to 120 order fine powder; Again Fructus Mori is cooked the airing post-treatment and be crushed to 120 order fineness; Pulverize separately was processed into 120 order fineness after other got Radix Notoginseng, Semen Cassiae drying, after above-mentioned whole powder are sieved by affiliated formula proportion mixing, made powder, or incapsulated.Every day 3 times, each 4-6 grain.
Embodiment 4: get Folium Mori 80 grams, Folium Ginkgo 80 grams, Fructus Mori 50 grams, Radix Et Rhizoma Fagopyri Tatarici 65 grams, Radix Notoginseng 50 grams, Semen Cassiae 60 grams respectively, earlier with exsiccant Folium Mori, Folium Ginkgo, Radix Et Rhizoma Fagopyri Tatarici pulverize separately to 120 order fine powder; Again Fructus Mori is cooked the airing post-treatment and be crushed to 120 order fineness; Pulverize separately was processed into 120 order fineness after other got Radix Notoginseng, Semen Cassiae drying, after above-mentioned whole powder are sieved by affiliated formula proportion mixing, made powder, or incapsulated.Every day 3 times, each 4-6 grain.

Claims (2)

1, the health care medicine of a kind of prevention and treatment diabetic complication is characterized in that it is made up of Folium Mori, Folium Ginkgo, Fructus Mori, Radix Et Rhizoma Fagopyri Tatarici, Radix Notoginseng, Semen Cassiae, and wherein the weight proportion of each component is:
50~80 parts on Folium Mori, 50~80 parts of Folium Ginkgos, 20~50 parts in Fructus Mori,
40~65 parts of Radix Et Rhizoma Fagopyri Tatarici, 25~50 parts of Radix Notoginseng, 40~60 parts of Semen Cassiaes.
2, the health care medicine of prevention according to claim 1 and treatment diabetic complication is characterized in that it is made up of Folium Mori, Folium Ginkgo, Fructus Mori, Radix Et Rhizoma Fagopyri Tatarici, Radix Notoginseng, Semen Cassiae, and wherein the weight proportion of each component is:
55 parts on Folium Mori, 60 parts of Folium Ginkgos, 30 parts in Fructus Mori,
50 parts of Radix Et Rhizoma Fagopyri Tatarici, 25 parts of Radix Notoginseng, 50 parts of Semen Cassiaes.
CN 200510012570 2005-06-04 2005-06-04 Health-care medicine for treating and preventing complication of diabetes mellitus Expired - Fee Related CN1287818C (en)

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Application Number Priority Date Filing Date Title
CN 200510012570 CN1287818C (en) 2005-06-04 2005-06-04 Health-care medicine for treating and preventing complication of diabetes mellitus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 200510012570 CN1287818C (en) 2005-06-04 2005-06-04 Health-care medicine for treating and preventing complication of diabetes mellitus

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CN1724004A true CN1724004A (en) 2006-01-25
CN1287818C CN1287818C (en) 2006-12-06

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102630790A (en) * 2012-05-08 2012-08-15 四川九通慧医药信息科技有限公司 Tartary buckwheat tea prepared by Ginkgo biloba leaf and preparation process thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102630790A (en) * 2012-05-08 2012-08-15 四川九通慧医药信息科技有限公司 Tartary buckwheat tea prepared by Ginkgo biloba leaf and preparation process thereof
CN102630790B (en) * 2012-05-08 2015-02-11 四川九通慧医药信息科技有限公司 Tartary buckwheat tea prepared by Ginkgo biloba leaf and preparation process thereof

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