CN1723937A

CN1723937A - Plaster contg. tuber of hyacinth bletilla for treating burns

Info

Publication number: CN1723937A
Application number: CNA2005100190539A
Authority: CN
Inventors: 孙传红
Original assignee: Individual
Current assignee: Individual
Priority date: 2005-07-06
Filing date: 2005-07-06
Publication date: 2006-01-25
Anticipated expiration: 2025-07-06
Also published as: CN1331517C

Abstract

A Chinese medicine in the form of plaster for treating burn, scald and skin infection ulcer is prepared from lidocaine, Vaseline, peanut oil and 8 Chinese-medicinal materials including bletilla tuber, sanguisorba root, rhubarb, borneol, etc through immersing, frying in oil, dissolving and filtering. Its advantage is high curative effect and no residual scar.

Description

Pseudobulbus Bletillae (Rhizoma Bletillae) burn pastes

Affiliated technical field:

The present invention relates to Chinese medicine unguentum external manufacture technology field, can be used for various water, fire, oil and chemical substance burn, burn, scald, also can be used for changing dressings of skin infection, ulcer and anorectal surgery postoperative.

Background technology:

At present, a lot of externally applied ointments just are used for market with the finished product plaster to burn, and the outer time spent is applied to wound surface with ointment earlier, cover with sterile gauze again, and complex operation, the medication inequality influences therapeutic effect; Perhaps wound surface directly is exposed in the air, surface skin does not have covering, patient's inconvenient activity, outside wound surface was exposed to for a long time, what moisturize lost, and caused the Water-Electrolyte disorder easily, the dust in air antibacterial is dropped on the wound surface easily simultaneously, has increased the probability that infects.

At present, though the method for treatment burn wound is numerous and complicated various, which kind of Therapeutic Method is ideal still can't evaluate.Seek based on the physiological regeneration reparation, the wound healing mode of no cicatrix has become the general trend and the leading trend of the present and the future's researching wound healing.

Summary of the invention:

The purpose of this invention is to provide a kind of Pseudobulbus Bletillae (Rhizoma Bletillae) burn subsides of novel therapeutic burn, replace traditional burn cream, after wound surface is sterilized, directly burn is sticked on wound surface, the no aqueous of utilizing burn to stick has ointment protection skin, and maintenance skin moistens and do not steep.Oil is and sticking, and subsides promptly do not wait characteristics bitterly, makes wound surface form layer protective layer, plays good putrefaction-removing granulation-promoting, anti-inflammatory analgetic, the effect of infection and accelerating wound healing.Technology contents of the present invention is achieved in that

Pseudobulbus Bletillae (Rhizoma Bletillae) burn pastes, and it is characterized in that: it is become to be grouped into by following materials of weight proportions: Chinese crude drug: Pseudobulbus Bletillae (Rhizoma Bletillae) 3.8-4.5%, Radix Sanguisorbae 3.8-4.5%, Cortex Phellodendri 2.5-3%, Radix Et Rhizoma Rhei 2.5-3%, Rhizoma Polygoni Cuspidati 2.5-3%, WUBEIZI 2.5-3%, Radix Arnebiae (Radix Lithospermi) 1.1-1.5%, Borneolum Syntheticum 2-2.5%; Substrate: Oleum Arachidis hypogaeae semen 65-70%, vaseline 8-9%; Western medicine material: lignocaine powder 0.06-0.07%.

The Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Sanguisorbae have tangible hemostasis, detumescence, granulation promoting, skin and bacteriostasis heal; Berberine in Cortex Phellodendri, Radix Et Rhizoma Rhei, the Rhizoma Polygoni Cuspidati, emodin, physcione etc. have good antibacterial action to gram positive bacteria, negative bacterium, fungus; WUBEIZI contains tannin, the histone at positions such as skin, mucosa, ulcer is solidified, and be astriction; In vitro tests all has significantly antibacterial and bactericidal action to staphylococcus aureus, streptococcus and bacillus pyocyaneus etc.; Radix Arnebiae (Radix Lithospermi) contains that acetylshikonin, Radix Arnebiae (Radix Lithospermi) are red, multiple how quinone derivative such as isobutyryl shikonin, has heat-clearing and toxic substances removing, promoting blood circulation and cooling blood and bacteriostasis.Other have refrigerant pain relieving, antipruritic, antiinflammation as Borneolum Syntheticum; Lignocaine has direct local anesthesia effect, and wound surface is changed dressings and can be made it painless, and this has played positive effect to the protection prevention and the control infection of wound surface undoubtedly; Substrate Oleum Arachidis hypogaeae semen, vaseline can provide a moistening relatively environment to burn wound, and this is extremely dark for the reparation of burn wound and the meaning of accelerating to heal.This prescription contains certain nutritional labeling and has the Chinese herbal medicine of blood circulation promoting and blood stasis dispelling, removing the necrotic tissue, promoting muscle growth functions, in accelerating wound, undue growth also capable of inhibiting cell, minimizing scar hyperplasia, and reach comparatively ideal wound healing effect, can shorten healing time significantly, reduce patient's misery, and have simple, convenient, be convenient to advantage such as nursing.

1, all Chinese medicine ingredients of product of the present invention and making flow process are secret prescription handed down in the family from generation to generation, through my clinical practice, its effective ingredient are more become rationally, and plaster is made patch, and be convenient and practical, safe and reliable.

2, all traditional Chinese medicinal materials assortments of product of the present invention do not relate to national Chinese medicine protection kind, and crude drug source is extensive, and price of medicinal material is cheap.

3, the burn cream of in the past making, oil, tincture are to cover with sterile gauze after medicine directly is applied to wound surface again.The present invention has selected for use the medicine of will burning directly to make burn and has pasted, and applies lid, in the sterilization wound surface, has reduced water evaporates and wound surface exposes in air, has reduced the probability that infects.

4, composition of the present invention has heat-clearing and toxic substances removing, putrefaction-removing granulation-promoting, and the dampness convergence,, the effect of anti-inflammatory analgetic has the healing time weak point, does not stay red trace after healing.

5, the present invention is no aqueous ointment, and color is a brown, is attached to can keep skin profit on the wound surface and do not steep, and oil and sticking pastes promptly not characteristics bitterly.

6, to have selected the patch intensive amount for use be 0.1% lignocaine local anesthetic in the present invention, wound surface there is direct anesthetic action, reduce patient's pain and can eliminate patient's feared state of mind, the energy expenditure that minimizing causes because of pain, the reparation of accelerated in wounds under non-pain state, less because of pasting intensive amount, the patient there is not obvious influence.

7, the present invention also can be used for various skin infections, changes dressings behind ulcer and the anorectal surgery, has putrefaction-removing granulation-promoting, the advantage of accelerating wound healing.

Adopt the present invention to answer points for attention:

1, to the careful usefulness of Oleum Arachidis hypogaeae semen allergy sufferers;

2, the general that is caused by burn wound being sent out the patient must use under burn doctor's guidance;

3, the careful usefulness of neonate and anemia of pregnant woman.

The specific embodiment:

Method for making 1 is: with the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Sanguisorbae, Cortex Phellodendri, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati, WUBEIZI, seven kinds of Chinese crude drugs such as Radix Arnebiae (Radix Lithospermi) are slightly pulverized by proportioning, with Oleum Arachidis hypogaeae semen with one week of herbal medicine immersion, oil and Chinese medicine are placed in the iron pan, after being heated to the oil boiling, when the fried Chinese medicine of continuation slow fire becomes yellow black (about 30 minutes of time), stop heating, when treating that oily temperature drop to 100 is spent, with Borneolum Syntheticum, vaseline adds in the pot, stirs fully dissolving, and carefully being filtered to does not have medicinal residues in the oil, be cooled to the lignocaine powder of 30 degree back addings 1%, stir into a paste, cooling back becomes Pseudobulbus Bletillae (Rhizoma Bletillae) burn cream, in 8 * 10cm gauze of will sterilize immersion burn cream promptly.

Method for making 2 is: the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Sanguisorbae, Cortex Phellodendri, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati, WUBEIZI, Radix Arnebiae (Radix Lithospermi) Chinese medicine primary crude drug directly are soaked in the Oleum Arachidis hypogaeae semen, and the time was two weeks, and is remaining with method for making 1.Be not suitable for using not Caledonia caine of lignocaine person.

Clinical data:

Burn is damage more common in daily life, productive labor and the war, the wherein clinical modal II degree burn that is.10 routine fire victims of this group outpatient service diagnosis and treatment are also in the majority with II degree burn.Employing the present invention treatment is carried out clinical observation to the patient.

10 examples are organized in treatment, wherein male 4 examples, and women 6 examples, 27 years old mean age, the I degree is scalded 1 example, area 5%, the II degree is scalded 7 examples, and the III degree is scalded 2 examples.Be not wait by 3 days in 20 minutes to treatment during scald.

Diagnostic criteria: with perusal and clinical symptoms is diagnostic criteria, is divided into three degree: the I degree: erythema appears in skin surface, and local red heat swells and ache.The II degree: bulla appears in skin surface, and the bleb skin breaks and forms rotten to the corn incrustation.III degree: the clinical manifestation of II degree is arranged, and form shallow at skin surface in ulcer.

The treatment standard: be divided into, better, differ from three kinds.Good: I degree burn was cured in 3 days, and the II burn was cured in 10 days, and III degree burn does not have cicatrix with healing in 20 days behind the wound healing.Better: I degree burn healing time is healing in 4 days, and II degree burn is with healing in 17 days, healing in the III degree burn 30 days, the III degree no cicatrix of burn or mild scar is arranged.Difference: the I degree burn wound healing time surpasses 5 days, and the II degree burn-healing time surpasses 20 days, and III degree burn wound's time surpassed more than 30 days, or wound surface has infection, ulcer is prolonged leaves spot after not healing, healing.

Therapeutic Method: wound surface is handled: burn wound is with the debridement of sterilizing of 0.1% bromo geramine.Administrated method: for extremity, trunk, the position that packs easily such as perineal position directly pastes with Pseudobulbus Bletillae (Rhizoma Bletillae) burn after the debridement and covers wound surface, the humidity that Pseudobulbus Bletillae (Rhizoma Bletillae) burn pastes is sticked oil dripping cream degree of being to drip, unsuitable too dry, burn welt edge is greater than wound surface 2-3cm, and the enclosing cover sterile gauze is wrapped up.For head and after having the hair position to cut off hair, the debridement wrapping.When particularly eye is burnt for facial burn, should check that eyes and an eye conjunctiva have or not burn, when burn is arranged, ask ophthalmic procedures; With behind the collyrium flushing eyes, do not apply erythromycin eye ointment in the eyes when having burn, hide eyes portion with sterile gauze, the debridement of then sterilizing again burn affected part covers burn and pastes, and keeps respiratory passage unblocked.Burn should be changed dressings once in early days in per 6 hours, changed dressings once in later per 12 hours-24 hours.Before changing dressings, wound surface left drug and liquefaction metabolite must be struck off gently at every turn, behind the routine disinfection, change Pseudobulbus Bletillae (Rhizoma Bletillae) burn again and paste.When wound surface has been formed a scab drying, reduce dressing change frequency gradually, prolong and to change dressings the time, heal fully to wound surface.Should not tear by force when the burn subsides have adhesion with wound surface, behind the application hydrogen peroxide dipping, take off gently, in case hemorrhage.

Therapeutic outcome:

Wound surface oozes out obvious minimizing after medication, I degree burn healed in 3 days, and II degree, III degree burn ooze out swelling and disappear in the time of 3-4 days.The equal I phase of all cases heals, and does not have 1 example and infects.Hospital stays is 5-16 days.10 examples were followed up a case by regular visits to 3 months---and 1 year, the result showed that shallow II degree, dark II degree wound surface all do not have the clear scar hypertrophy, and 1 routine facial area has pigmentation to disappear after 4 months.III degree 1 example of burning leaves pigmentation, disappears after treating, and all the other all feel satisfied.

Clinical case report (10 example)

1, Huang Wenguang, man, 3 years old.Scald right lower limb, area 4%, mix, went to a doctor in back 1 hour in scalding, paste through debridement covering Pseudobulbus Bletillae (Rhizoma Bletillae) burn with II degree, III degree because of boiled water, behind the enclosing cover sterile gauze, with bandaging, pain is promptly ended.The 1st day, changed dressings 1 time in 12 hours, change dressings every day thereafter 1 time, stop to oozing out, change dressings every day 1 time, anti symptom treatment was fully recovered in 12 days simultaneously.

2, Zhang Xiangyuan, woman, 48 years old.Facial area and cervical region boiled water are scalded, area 3%, the II degree is scalded, and goes to a doctor eyes eyelid height swelling during first visit in back 24 hours in burn, the vesicle that as seen facial area and cervical region differ in size, make a definite diagnosis after eyeball portion do not have scald, after debridement, cover Pseudobulbus Bletillae (Rhizoma Bletillae) burn and paste the eye anti symptom treatment, change dressings recovery from illness on the 4th every day 1 time.

3, Wang Dalan, woman, 62 years old.Hundred storages in the Xiaogan, two buttocks, thigh boiled water scald, II degree when having a bath, area 6%, go to a doctor in hindering back 36 hours, two buttocks, the swelling of thigh and calf height during first visit, the vesicle that as seen differs in size, visible low-grade infection, covering Pseudobulbus Bletillae (Rhizoma Bletillae) burn behind debridement, disinfection pastes, through anti symptom treatment such as anti-inflammations, change dressings recovery from illness in 8 days every day 1 time.

4, Zou Yi, woman, 4 years old.The right leg boiled water is scalded, area 2%, and II degree burn was gone to a doctor in scalding, is pasted through debridement covering Pseudobulbus Bletillae (Rhizoma Bletillae) burn in back 1 hour, and behind the enclosing cover sterile gauze, with bandaging, pain is promptly ended, and children's's sob stops.The 1st day, changed dressings 1 time in 12 hours, changed dressings 1 time in per thereafter two days, stop to oozing out, change dressings every day 1 time, anti symptom treatment was fully recovered in 7 days simultaneously.

5, Zhang Huiru, Luo Majie, woman, 33 years old.The I degree, 5% went to a doctor in burn in back 4 hours scalds right lower limb, covers Pseudobulbus Bletillae (Rhizoma Bletillae) burn through debridement and paste because of boiled water, and behind the enclosing cover sterile gauze, with bandaging, pain is promptly ended.The 1st day, changed dressings 1 time in 12 hours, change dressings recovery from illness in 3 days thereafter every day 1 time.

6, Song Qing, woman, 41 years old.II, the III degree, breast, abdomen, lap,, area 9%, went to a doctor breast during first visit in back 24 hours in burn.Abdomen.Vesicle that as seen lap differs in size and one's water breaks bleb skin, the surface forms shallow in ulcer, covers Pseudobulbus Bletillae (Rhizoma Bletillae) burn and paste after debridement, covers with sterile gauze, changes dressings recovery from illness in 19 days every day 1 time.

7, Liu Zhongzhi, man, 56 years old.Went to a doctor in back 24 hours in burn and to scald right lower limb, area 4%, II degree because of boiled water and scald, to go to a doctor in back 1 hour in scalding, to cover Pseudobulbus Bletillae (Rhizoma Bletillae) burn through debridement and paste, behind the enclosing cover sterile gauze, with bandaging, pain is promptly ended.The 1st day, changed dressings 1 time in 12 hours, change dressings every day thereafter 1 time, stop to oozing out, change dressings recovery from illness in 12 days thereafter every day 1 time.

8, Yang Yanxia, woman, 22 years old.Hubei Xiaogan, right thigh boiled water are scalded, area 2%, and the II degree is scalded, and scald right lower limb, paste through debridement covering Pseudobulbus Bletillae (Rhizoma Bletillae) burn, behind the enclosing cover sterile gauze, with bandaging because of boiled water in burn prescription on individual diagnosis in back 24 hours.The 1st day, changed dressings 1 time in 12 hours, stop to oozing out, change dressings every day 1 time, anti symptom treatment was fully recovered in 5 days simultaneously.

9, Liu Bing, man, 3., scald right lower limb, area 4%, II degree, went to a doctor in back 1 hour, cover Pseudobulbus Bletillae (Rhizoma Bletillae) burn through debridement and paste because of boiled water in scalding, behind the enclosing cover sterile gauze, with bandaging, pain is promptly ended, children's's sob stops.The 1st day, changed dressings 1 time in 12 hours, change dressings every day thereafter 1 time, stop to oozing out, every day, horse was changed dressings 1 time, and anti symptom treatment was fully recovered in 12 days simultaneously.

10, Chen Guodong, man, soldier, 24 years old.The facial area electric welding II degree of burning was gone to a doctor in burn in back 2 hours, eyes eyelid height swelling during first visit, and the vesicle that as seen facial area and cervical region differ in size covers Pseudobulbus Bletillae (Rhizoma Bletillae) burn and pastes after debridement, and the eye anti symptom treatment is changed dressings 1 every day, recovery from illness on the 4th.

Claims

Pseudobulbus Bletillae (Rhizoma Bletillae) burn pastes, and its characteristic is " it is made by the former medicine of following weight proportion, Pseudobulbus Bletillae (Rhizoma Bletillae) 3.8-4.5%; Radix Sanguisorbae 3.8-4.5%; Cortex Phellodendri 2.5-3%, Radix Et Rhizoma Rhei 2.5-3%, Rhizoma Polygoni Cuspidati 2.5-3%; WUBEIZI 2.5-3%; Radix Arnebiae (Radix Lithospermi) 1.1-1.5%, Borneolum Syntheticum 2-2.5%, (substrate) Oleum Arachidis hypogaeae semen 65-70%; vaseline 8-9%, lignocaine powder 0.06-0.07% ".