CN1709266A - Ointment for treating skin disease and its production method - Google Patents
Ointment for treating skin disease and its production method Download PDFInfo
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- CN1709266A CN1709266A CN 200510012613 CN200510012613A CN1709266A CN 1709266 A CN1709266 A CN 1709266A CN 200510012613 CN200510012613 CN 200510012613 CN 200510012613 A CN200510012613 A CN 200510012613A CN 1709266 A CN1709266 A CN 1709266A
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- ointment
- acetate
- bactrim
- chlorphenamine
- triamcinolone acetonide
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Abstract
The present invention relates to an ointment for external application for curing dermatosises of psoriasis, neurodermatitis, allergic dermatitis, cutaneous pruritus, beriberi, mosquito bite and infantile eczema, etc. with obvious therapeutic effect. Said ointment is made up by using (by wt%) 30-60% of tramcinolone acetonide acetate urea cream, 15-30% of compound sulfamethoxazole, 10-20% of prednisone acetate and 10-20% of chlorpheniramine maleate. Besides, said invention also provides its production method and concrete steps.
Description
Technical field
The present invention relates to a kind of ointment, dermopathic ointment of specifically a kind of treatment and production method.
Background technology
The dermopathic medicament categories of treatment is a lot of at present, commonly used has: PIKANGWANG, tinea must be only, daktarin etc., these medicines can be alleviated the dermatosis misery, and can stop onset area temporarily, but because dermatosis is the disease of a kind of stubbornness, easy recurrence, these medicines can only play mitigation, can not thoroughly cure.And not remarkable for pertinacious disease effects such as treatment infant eczema, psoriasiss, cure rate is lower.
Summary of the invention
The technical problem to be solved in the present invention one provides a kind ofly to be combined four kinds of medicines in proportion, relieving itching and eliminating swelling, and penetrance is good, has no side effect the dermopathic ointment of the treatment that cure rate is high.Two provide a kind of with four kinds of drug regimens together, be made into the production method of ointment.Overcome many deficiencies of background technology.
Solve the problems of the technologies described above and adopt following technical scheme: the dermopathic ointment of a kind of treatment, constitute by triamcinolone acetonide acetate urea cream, bactrim, prednisone acetate, chlorphenamine, the weight percent content of each medicine is: triamcinolone acetonide acetate urea cream 30～60, bactrim 15～30, prednisone acetate 10～20, chlorphenamine 10～20.
A kind of production method for the treatment of dermopathic ointment earlier with bactrim, prednisone acetate, chlorphenamine pulverize, mixes powder and triamcinolone acetonide acetate urea cream then, stirs, and makes ointment.
The pharmacological action of four kinds of medicines among the present invention:
The triamcinolone acetonide acetate urea cream: be Aeroseb-Dex, external has anti-inflammatory, antiallergic and itching-relieving action.Carbamide solubilized keratoprotein increases proteinic hydration, has concurrently antipruriticly, antibioticly waits effect, and can increase the endermic penetrance of medicine.
Bactrim: this product is a disulfonamide, is the compound preparation of sulphur peace oxazole, trimethoprim, when external to trachoma substance at night, star-shaped nocardia, protozoon, toxoplasma etc. has the effect of good antimicrobial acivity.
Prednisone acetate: have antiinflammatory, antiallergic, rheumatism immunosuppressive action, this product can alleviate and prevent to organize reaction to inflammation, thereby the performance that reduces inflammation, the inflammation-inhibiting cell prevents or suppresses cell-mediated immunoreation and reduce the binding ability of immunity to globulin and cell surface receptor.
Chlorphenamine: this product has good inhibition effect to the telangiectasis due to the anaphylaxis, the permeability that reduces blood capillary.
Owing to adopted technique scheme, the present invention is applicable to diseases such as treatment psoriasis, neurodermatitis, allergic dermatitis, skin pruritus, brothers' crowfoot cracks, beriberi, mosquito bite, infantile eczema with four kinds of drug regimens together.Anti-inflammation detumescence is effective, the cure rate height, and relapse rate is low.This product is a medicine for external use, facts have proved through the treatment of 300 examples, without any toxic and side effects.
The specific embodiment
The present invention is a raw material with triamcinolone acetonide acetate urea cream, bactrim, prednisone acetate, the chlorphenamine of selling on the market, makes ointment.The weight percent content of each medicine is: triamcinolone acetonide acetate urea cream 30～60, bactrim 15～30, prednisone acetate 10～20, chlorphenamine 10～20.
The degree specific embodiment of four kinds of medicines is as follows:
Embodiment 1: triamcinolone acetonide acetate urea cream 30, bactrim 30, prednisone acetate 20, chlorphenamine 20.
Embodiment 2: triamcinolone acetonide acetate urea cream 45, bactrim 25, prednisone acetate 15, chlorphenamine 15.
Embodiment 3: triamcinolone acetonide acetate urea cream 55, bactrim 15, prednisone acetate 20, chlorphenamine 10.
Embodiment 4: triamcinolone acetonide acetate urea cream 60, bactrim 15, prednisone acetate 10, chlorphenamine 15.
Embodiment 5: triamcinolone acetonide acetate urea cream 44, bactrim 26, prednisone acetate 16, chlorphenamine 14.
Production method embodiment of the present invention:
Earlier with bactrim, prednisone acetate, chlorpheniramine maleate tablets grinds to form smalls, takes by weighing three kinds of medicine smalls respectively according to the ratio among the embodiment, three kinds of medicamental pulverata is mixed put into the triamcinolone acetonide acetate urea cream, stir, make white ointment and be the present invention.
Operation embodiment
1, weigh bactrim 26 gram, prednisone acetate 16 grams, chlorphenamine 14 grams, respectively with lapping apparatus with they pulverizations, three kinds of smalls are mixed put into 44 gram triamcinolone acetonide acetate urea creams and stir, make white ointment.
2, weigh bactrim 15 gram, prednisone acetate 10 grams, chlorphenamine 15 grams, respectively with lapping apparatus with they pulverizations, three kinds of smalls are mixed put into 60 gram triamcinolone acetonide acetate urea creams and stir, make white ointment.
3, weigh bactrim 15 gram, prednisone acetate 20 grams, chlorphenamine 10 grams, respectively with lapping apparatus with they pulverizations, three kinds of smalls are mixed put into 55 gram triamcinolone acetonide acetate urea creams and stir, make white ointment.
4, weigh bactrim 25 gram, prednisone acetate 15 grams, chlorphenamine 15 grams, respectively with lapping apparatus with they pulverizations, three kinds of smalls are mixed put into 45 gram triamcinolone acetonide acetate urea creams and stir, make white ointment.
5, weigh bactrim 30 gram, prednisone acetate 20 grams, chlorphenamine 20 grams, respectively with lapping apparatus with they pulverizations, three kinds of smalls are mixed put into 30 gram triamcinolone acetonide acetate urea creams and stir, make white ointment.Production method of the present invention is carried out in aseptic environments.Finished product is preserved at low temperature black out place.
Using method embodiment of the present invention:
External, 2 times on the one, before the medication, clean the affected part, to dip in ointment with cotton swab and smear the affected part, the application area of ointment is greater than the affected part, and soft affected part 5 minutes.
Model case:
Jiang, the man, 4 years old, suffered from facial circle tinea in 1986, in a tame hospitalize several months of Tangshan, this product is used in the commentaries on classics of not getting better instead, and three days take effect, and cure in 15 days, so far not recurrence.
Zheng, the woman, 17 years old, nineteen ninety-five was suffered from eczema, suffered from during several families hospital treatment fashion in Tangshan, began to smear this medicine 98 year autumn, and three days take effect, recovery from illness recurrence so far about month.
The Wang, 20 years old, the tinea manuum, coating is about 1 month, and recovery from illness is not recurred so far.
Zhu, the woman suffers from psoriasis, smears the present invention 1 month, recovery from illness, not recurrence so far.
Dong, 8 years old, the man, eczema around the lip is smeared about two weeks and is fully recovered.
Poplar, 6 months, the facial eczema of children's in several families hospitalize commentariess on classics of not getting better, was used the present invention instead and was taken effect in three days, fully recovers about 15 days.
Since 1986, treat 300 routine patients with the present invention, 270 people recovery from illness, cure rate is 90% (wherein the cure rate of eczema is 100%), and relapse rate is zero, and effective percentage is 98%.
Claims (2)
1, the dermopathic ointment of a kind of treatment, constitute by triamcinolone acetonide acetate urea cream, bactrim, prednisone acetate, chlorphenamine, the weight percent content that it is characterized in that each medicine is: triamcinolone acetonide acetate urea cream 30～60, bactrim 15～30, prednisone acetate 10～20, chlorphenamine 10～20.
2, a kind of according to claim 1 the described rule of virtue treat the production method of dermopathic ointment, it is characterized in that,, then powder and triamcinolone acetonide acetate urea cream are mixed earlier with bactrim, prednisone acetate, chlorphenamine pulverize, stir, make ointment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510012613 CN1709266A (en) | 2005-06-17 | 2005-06-17 | Ointment for treating skin disease and its production method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510012613 CN1709266A (en) | 2005-06-17 | 2005-06-17 | Ointment for treating skin disease and its production method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1709266A true CN1709266A (en) | 2005-12-21 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200510012613 Pending CN1709266A (en) | 2005-06-17 | 2005-06-17 | Ointment for treating skin disease and its production method |
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| CN (1) | CN1709266A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101190228B (en) * | 2006-11-22 | 2011-05-11 | 上海新亚药业闵行有限公司 | Compound triamcinolone acetonide acetate solution production technology |
| CN106492198A (en) * | 2016-11-15 | 2017-03-15 | 冯炳养 | One kind is used for effecting a radical cure psoriasic ointment |
| CN110327319A (en) * | 2019-07-10 | 2019-10-15 | 李建 | A kind of drug and preparation method thereof for treating neurodermatitis |
-
2005
- 2005-06-17 CN CN 200510012613 patent/CN1709266A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101190228B (en) * | 2006-11-22 | 2011-05-11 | 上海新亚药业闵行有限公司 | Compound triamcinolone acetonide acetate solution production technology |
| CN106492198A (en) * | 2016-11-15 | 2017-03-15 | 冯炳养 | One kind is used for effecting a radical cure psoriasic ointment |
| CN110327319A (en) * | 2019-07-10 | 2019-10-15 | 李建 | A kind of drug and preparation method thereof for treating neurodermatitis |
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