CN1682828A - Yinhuang lung clearing capsule and its preparing method - Google Patents

Yinhuang lung clearing capsule and its preparing method Download PDF

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CN1682828A
CN1682828A CN 200510008795 CN200510008795A CN1682828A CN 1682828 A CN1682828 A CN 1682828A CN 200510008795 CN200510008795 CN 200510008795 CN 200510008795 A CN200510008795 A CN 200510008795A CN 1682828 A CN1682828 A CN 1682828A
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parts
capsule
lung clearing
lepidii
semen
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CN100588415C (en
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高尚
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Hunan Anbang Pharmaceutical Co ltd
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佘定国
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Abstract

The present invention discloses a kind of lung clearing Yinhuang capsule prepared with gingko leaf, roasted ephedra, northern pepperweed seed, almond, thunberg fritillary bulb and other nine kinds of Chinese medicinal materials. The lung clearing Yinhuang capsule is used in the treatment of retention of phlegm-heat in the lung caused acute attack of chronic bronchitis, and has the advantages of taking convenience and high treating effect.

Description

Yinhuang lung clearing capsule and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine preparation with and preparation method thereof, be a kind of capsule specifically with removing heat from the lung and dissipating phlegm, function of relieving cough and calming asthma, be used for the treatment of chronic bronchitis.
Background technology
Bronchitis is a kind of commonly encountered diseases, can be caused by influenza, belongs to traditional Chinese medical science cough scope, its easily repeatedly and the course of disease long, fall ill the cold season of being everlasting.As obstinate, can constantly make progress and understand concurrent emphysema, pulmonary heart disease, respiratory failure, even threat to life.The phlegm-heat obstructing in the lung of acute episode of chronic bronchitis belongs to bronchitic a kind of Clinical types, and its symptom is for cough is coughed up phlegm, expectorant yellow glue, asthma uncomfortable in chest, thirsty, the dry stool yellowish urine of generating heat, red tongue with yellowish and greasy fur etc.Bring very big misery to the patient during outbreak.At present, treat this sick Chinese medicine preparation and mostly be syrup, oral liquid, all will use the sweeting agent flavoring, few as the correctives consumption, the difficult usefulness of bitter in the mouth then, how correctives can reduce drug effect again.
Summary of the invention
The object of the present invention is to provide a kind of Yinhuang lung clearing capsule of syndrome of phlegm-heat obstructing lung treatment usefulness of acute episode of chronic bronchitis, this capsule has taking convenience, eutherapeutic characteristics.
A kind of Yinhuang lung clearing capsule is the capsule of being made by the raw material of following parts by weight:
55~65 parts of lepidii,semens, 35~40 parts in Herba Ephedrae (processing), 40~50 parts of Semen Armeniacae Amarums, 40~50 parts of Bulbus Fritillariae Thunbergiis, 40~50 parts of Folium Eriobotryaes, 27~32 parts of Folium Isatidiss, 40~50 parts of Rhizoma Acori Graminei, 40~50 parts of Rhizoma Dioscoreae Nipponicae, 27~32 parts of Herba Achilleaes, 40~50 parts of Folium Ginkgos, 12~18 parts of Fructus Schisandrae Chinensis, 12~18 parts of Fructus Aurantii Immaturuss, 55~65 parts of Gypsum Fibrosum, 12~18 parts in Radix Glycyrrhizae.
Preferred prescription is the capsule of being made by the raw material of following parts by weight:
60 parts of lepidii,semens, 37.5 parts in Herba Ephedrae (processing), 45 parts of Semen Armeniacae Amarums, 45 parts of Bulbus Fritillariae Thunbergiis, 45 parts of Folium Eriobotryaes, 30 parts of Folium Isatidiss, 45 parts of Rhizoma Acori Graminei, 45 parts of Rhizoma Dioscoreae Nipponicae, 30 parts of Herba Achilleaes, 45 parts of Folium Ginkgos, 15 parts of Fructus Schisandrae Chinensis, 15 parts of Fructus Aurantii Immaturuss, 60 parts of Gypsum Fibrosum, 15 parts in Radix Glycyrrhizae.
The present invention also provides the preparation method of above-mentioned Yinhuang lung clearing capsule, and its process is:
(1) takes by weighing the Chinese medicine of respectively distinguishing the flavor of by prescription;
(2) Herba Ephedrae is ground into fine powder, standby;
(3) lepidii,semen, Semen Armeniacae Amarum, Bulbus Fritillariae Thunbergii, Fructus Aurantii Immaturus, Fructus Schisandrae Chinensis are extracted at the room temperature dipping with ethanol, reclaim ethanol in the extracting solution, be condensed into extractum;
(4) medicinal residues after the alcohol leaching in the step (3) are decocted with remaining eight flavor medicine water, the medicinal liquid that decocts is condensed into extractum;
(5) extract dry that makes in above-mentioned steps (3) and the step (4) is become dry extract, be ground into fine powder then;
(6) it is an amount of the Herba Ephedrae fine powder that makes in the step (2) and fine powder in the step (5) to be mixed and add starch, granulates, and incapsulates.
In the preparation method of above-mentioned Yinhuang lung clearing capsule, lepidii,semen, Semen Armeniacae Amarum, Bulbus Fritillariae Thunbergii, Fructus Aurantii Immaturus, Fructus Schisandrae Chinensis extract with alcohol dipping in the step (3), can adopt following method so that the extraction of raw material medicinal component is more abundant: lepidii,semen, Semen Armeniacae Amarum, Bulbus Fritillariae Thunbergii, Fructus Aurantii Immaturus, Fructus Schisandrae Chinensis are added the quintuple alcohol dipping, flood altogether three times, each 24 hours, filter the extracting solution that the back merges three dippings.
Described ethanol is that 70% ethanol is ideal with concentration.
Decocting methods of above-mentioned steps (4) Chinese medicine slag and remaining eight flavor medicines are: the medicinal residues after the alcohol dipping and remaining eight flavor medicine one are reinstated 10 times of water gagings decoction secondaries, and each 1 hour, collecting decoction then.
Every powder charge 0.15g of Yinhuang lung clearing capsule, each oral 3, three times on the one, seven days is a course of treatment.Be not taken by pregnant women.Contain ephedrine in this product composition, tachycardia, the careful usefulness of hyperpietic.Note careful and heart tonifying glycoside drug combination.
Yinhuang lung clearing capsule of the present invention, be capsule, characteristics with taking convenience, and except that medicinal component, have only a spot of starch as excipient, make medicinal component content height, good effect, can be used for the treatment of the syndrome of phlegm-heat obstructing lung of acute episode of chronic bronchitis, have the effect of removing heat from the lung and dissipating phlegm, relieving cough and asthma.In the side: Bulbus Fritillariae Thunbergii, Folium Eriobotryae, the Rhizoma Acori Graminei relieving cough and resolving phlegm, the Herba Ephedrae depressed lung-energy dispersing, the Gypsum Fibrosum eliminating heat from the lung, the Folium Isatidis heat-clearing and toxic substances removing, lepidii,semen, Fructus Aurantii Immaturus, Semen Armeniacae Amarum promoting the circulation of QI sending down the abnormal ascending QI, Rhizoma Dioscoreae Nipponicae relieving cough and asthma, Folium Ginkgo are astringed the lung and are relievingd asthma, the Herba Achilleae eliminating inflammation and expelling toxin, the Fructus Schisandrae Chinensis QI invigorating, promote the production of body fluid, quench one's thirst Radix Glycyrrhizae QI invigorating tonifying the lung void, promoting the production of body fluid to quench thirst is also separated Herba Achilleae toxicity, with all medicines, the above-mentioned medicine of respectively distinguishing the flavor of share, a surname falls and is harmonious, clear respectful collaborative, its benefit is clear, to reach removing heat from the lung and dissipating phlegm, the combined therapy effect of relieving cough and asthma, clinical trial shows, Yinhuang lung clearing capsule of the present invention is executed to the ill and is controlled, and combined therapy effect is remarkable.
The specific embodiment
Below in conjunction with specific embodiment Yinhuang lung clearing capsule of the present invention is described further.
Embodiment 1
Yinhuang lung clearing capsule adopts the raw material of Chinese medicine of following weight to make, and its prescription is: lepidii,semen 60g, Herba Ephedrae (processing) 37.5g, Semen Armeniacae Amarum 45g, Bulbus Fritillariae Thunbergii 45g, Folium Eriobotryae 45g, Folium Isatidis 30g, Rhizoma Acori Graminei 45g, Rhizoma Dioscoreae Nipponicae 45g, Herba Achilleae 30g, Folium Ginkgo 45g, Fructus Schisandrae Chinensis 15g, Fructus Aurantii Immaturus 15g, Gypsum Fibrosum 60g, Radix Glycyrrhizae 15g.
Above-mentioned 14 flavor Chinese medicines are weighed by prescription, Herba Ephedrae is ground into fine powder, standby.Lepidii,semen, Semen Armeniacae Amarum, Bulbus Fritillariae Thunbergii, Fructus Aurantii Immaturus, Fructus Schisandrae Chinensis are added quintuple 70% ethanol flood three times in room temperature, each 24 hours, filter, merge three times extracting solution, reclaim ethanol in the extracting solution, it is the extractum of 1.05 (50 ℃) that concentrating under reduced pressure becomes relative density.The decocting that eight flavor medicines such as the medicinal residues after the alcohol leaching and remaining Folium Eriobotryae add 10 times of amounts boils secondary, and each 1 hour, collecting decoction was evaporated to the extractum that relative density is about 1.1 (50 ℃).Above two kinds of extractum are merged, and reconcentration to relative density is about the extractum of 1.2 (50 ℃), and vacuum drying becomes dry extract again, and is ground into fine powder, adds above-mentioned Herba Ephedrae fine powder then, and it is an amount of to add starch, granulates, and dresses up 1000 of capsules, and every contains 0.15g, promptly.
Embodiment 2
Yinhuang lung clearing capsule is for to be made by lepidii,semen 65g, Herba Ephedrae (processing) 35g, Semen Armeniacae Amarum 48g, Bulbus Fritillariae Thunbergii 40g, Folium Eriobotryae 50g, Folium Isatidis 27g, Rhizoma Acori Graminei 50g, Rhizoma Dioscoreae Nipponicae 40g, Herba Achilleae 32g, Folium Ginkgo 40g, Fructus Schisandrae Chinensis 18g, Fructus Aurantii Immaturus 12g, Gypsum Fibrosum 65g, Radix Glycyrrhizae 18g in the present embodiment.
Above-mentioned 14 flavor Chinese medicines are weighed by prescription, Herba Ephedrae is ground into fine powder, standby.Lepidii,semen, Semen Armeniacae Amarum, Bulbus Fritillariae Thunbergii, Fructus Aurantii Immaturus, Fructus Schisandrae Chinensis are added octuple amount 75% ethanol flood secondary in room temperature, each 26 hours, filter, merge secondary raffinate, reclaim ethanol in the extracting solution, it is the extractum of 1.05 (50 ℃) that concentrating under reduced pressure becomes relative density.The decocting that eight flavor medicines such as the medicinal residues after the alcohol leaching and remaining Folium Eriobotryae add 10 times of amounts boils secondary, and each 1 hour, collecting decoction was evaporated to the extractum that relative density is about 1.1 (50 ℃).Above two kinds of extractum are merged, and reconcentration to relative density is about the extractum of 1.2 (50 ℃), and vacuum drying becomes dry extract again, is ground into fine powder, adds above-mentioned Herba Ephedrae fine powder, and it is an amount of to add starch, granulates, and dresses up 1000 of capsules, and every contains 0.15g, promptly.
Embodiment 3
Yinhuang lung clearing capsule is for to be made by lepidii,semen 55g, Herba Ephedrae (processing) 40g, Semen Armeniacae Amarum 41g, Bulbus Fritillariae Thunbergii 50g, Folium Eriobotryae 40g, Folium Isatidis 32g, Rhizoma Acori Graminei 40g, Rhizoma Dioscoreae Nipponicae 50g, Herba Achilleae 27g, Folium Ginkgo 50g, Fructus Schisandrae Chinensis 12g, Fructus Aurantii Immaturus 18g, Gypsum Fibrosum 55g, Radix Glycyrrhizae 12g in the present embodiment.
Above-mentioned 14 flavor Chinese medicines are weighed by prescription, Herba Ephedrae is ground into fine powder, standby.Lepidii,semen, Semen Armeniacae Amarum, Bulbus Fritillariae Thunbergii, Fructus Aurantii Immaturus, Fructus Schisandrae Chinensis are added six times of amount 75% ethanol flood three times in room temperature, each 24 hours, filter, merge three times extracting solution, reclaim ethanol in the extracting solution, it is the extractum of 1.05 (50 ℃) that concentrating under reduced pressure becomes relative density.The decocting that eight flavor medicines such as the medicinal residues after the alcohol leaching and remaining Folium Eriobotryae add seven times of amounts boils three times, and each 1.2 hours, collecting decoction was evaporated to the extractum that relative density is about 1.1 (50 ℃).Above two kinds of extractum are merged, and reconcentration to relative density is about the extractum of 1.2 (50 ℃), and vacuum drying becomes dry extract again, is ground into fine powder, adds above-mentioned Herba Ephedrae fine powder, and it is an amount of to add starch, granulates, and dresses up 1000 of capsules, and every contains 0.15g, promptly.

Claims (6)

1, a kind of Yinhuang lung clearing capsule is characterized in that, is the capsule of being made by the raw material of following parts by weight:
55~65 parts of lepidii,semens, 35~40 parts in Herba Ephedrae (processing), 40~50 parts of Semen Armeniacae Amarums,
40~50 parts of Bulbus Fritillariae Thunbergiis, 40~50 parts of Folium Eriobotryaes, 27~32 parts of Folium Isatidiss,
40~50 parts of Rhizoma Acori Graminei, 40~50 parts of Rhizoma Dioscoreae Nipponicae, 27~32 parts of Herba Achilleaes,
40~50 parts of Folium Ginkgos, 12~18 parts of Fructus Schisandrae Chinensis, 12~18 parts of Fructus Aurantii Immaturuss,
55~65 parts of Gypsum Fibrosum, 12~18 parts in Radix Glycyrrhizae.
2, Yinhuang lung clearing capsule as claimed in claim 1 is characterized in that, is the capsule of being made by the raw material of following parts by weight:
60 parts of lepidii,semens, 37.5 parts in Herba Ephedrae (processing), 45 parts of Semen Armeniacae Amarums,
45 parts of Bulbus Fritillariae Thunbergiis, 45 parts of Folium Eriobotryaes, 30 parts of Folium Isatidiss,
45 parts of Rhizoma Acori Graminei, 45 parts of Rhizoma Dioscoreae Nipponicae, 30 parts of Herba Achilleaes,
45 parts of Folium Ginkgos, 15 parts of Fructus Schisandrae Chinensis, 15 parts of Fructus Aurantii Immaturuss,
60 parts of Gypsum Fibrosum, 15 parts in Radix Glycyrrhizae.
3, the preparation method of the described Yinhuang lung clearing capsule of a kind of claim 1 is characterized in that this method is:
(1) takes by weighing the Chinese medicine of respectively distinguishing the flavor of by prescription;
(2) Herba Ephedrae is ground into fine powder, standby;
(3) lepidii,semen, Semen Armeniacae Amarum, Bulbus Fritillariae Thunbergii, Fructus Aurantii Immaturus, Fructus Schisandrae Chinensis are extracted at the room temperature dipping with ethanol, reclaim ethanol in the extracting solution, be condensed into extractum;
(4) medicinal residues after the alcohol leaching in the step (3) are decocted with remaining eight flavor medicine water, the medicinal liquid that decocts is condensed into extractum;
(5) extract dry that makes in above-mentioned steps (3) and the step (4) is become dry extract, be ground into fine powder then;
(6) it is an amount of the Herba Ephedrae fine powder that makes in the step (2) and fine powder in the step (5) to be mixed and add starch, granulates, and incapsulates.
4, the preparation method of Yinhuang lung clearing capsule as claimed in claim 3, it is characterized in that, the method that lepidii,semen, Semen Armeniacae Amarum, Bulbus Fritillariae Thunbergii, Fructus Aurantii Immaturus, Fructus Schisandrae Chinensis extract with alcohol dipping in the above-mentioned steps (3) is: lepidii,semen, Semen Armeniacae Amarum, Bulbus Fritillariae Thunbergii, Fructus Aurantii Immaturus, Fructus Schisandrae Chinensis are added the quintuple alcohol dipping, flood altogether three times, each 24 hours, filter the extracting solution that the back merges three dippings.
5, as the preparation method of claim 3 or 4 described Yinhuang lung clearing capsules, it is characterized in that: described concentration of ethanol is 70%.
6, as the preparation method of claim 3 or 4 described Yinhuang lung clearing capsules, it is characterized in that, decocting methods of above-mentioned steps (4) Chinese medicine slag and remaining eight flavor medicines are: the medicinal residues after the alcohol dipping and remaining eight decocting that medicines one reinstate 10 times of amounts of distinguishing the flavor of are boiled secondary, each 1 hour, collecting decoction then.
CN200510008795A 2005-03-01 2005-03-01 Capsule for treating chronic bronchitis and its preparing method Active CN100588415C (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102727733A (en) * 2012-07-05 2012-10-17 许瑞琴 Traditional Chinese medicine used for treating chronic bronchitis
CN103272114A (en) * 2013-06-13 2013-09-04 湖南安邦制药有限公司 Yinhuang medicine for clearing away lung-heat and preparation method thereof
CN103272113A (en) * 2013-06-13 2013-09-04 湖南安邦制药有限公司 Yinhuang granule for clearing away the lung-heat and preparation method thereof
CN103285225A (en) * 2013-06-13 2013-09-11 湖南安邦制药有限公司 Yinhuang lung-heat-clearing troche and preparation method thereof
CN104792889A (en) * 2015-02-13 2015-07-22 湖南安邦制药有限公司 Flos lonicerae and radix scutellariae lung-clearing preparation fingerprint spectrum establishment method and standard fingerprint spectrum and application thereof
CN107884508A (en) * 2017-04-16 2018-04-06 湖南安邦制药有限公司 The quality determining method of Yinhuang lung clearing capsule
CN114099610A (en) * 2021-12-22 2022-03-01 湖南安邦制药股份有限公司 Application of traditional Chinese medicine composition in preparation of medicine and/or non-therapeutic reagent for preventing and treating rhinovirus diseases

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102727733B (en) * 2012-07-05 2013-10-16 许瑞琴 Traditional Chinese medicine used for treating chronic bronchitis
CN102727733A (en) * 2012-07-05 2012-10-17 许瑞琴 Traditional Chinese medicine used for treating chronic bronchitis
CN103285225B (en) * 2013-06-13 2015-07-15 湖南安邦制药有限公司 Yinhuang lung-heat-clearing troche and preparation method thereof
CN103285225A (en) * 2013-06-13 2013-09-11 湖南安邦制药有限公司 Yinhuang lung-heat-clearing troche and preparation method thereof
CN103272113A (en) * 2013-06-13 2013-09-04 湖南安邦制药有限公司 Yinhuang granule for clearing away the lung-heat and preparation method thereof
CN103272114B (en) * 2013-06-13 2015-07-15 湖南安邦制药有限公司 Yinhuang medicine for clearing away lung-heat and preparation method thereof
CN103272114A (en) * 2013-06-13 2013-09-04 湖南安邦制药有限公司 Yinhuang medicine for clearing away lung-heat and preparation method thereof
CN103272113B (en) * 2013-06-13 2015-07-15 湖南安邦制药有限公司 Yinhuang granule for clearing away the lung-heat and preparation method thereof
CN104792889A (en) * 2015-02-13 2015-07-22 湖南安邦制药有限公司 Flos lonicerae and radix scutellariae lung-clearing preparation fingerprint spectrum establishment method and standard fingerprint spectrum and application thereof
CN104792889B (en) * 2015-02-13 2016-08-17 湖南安邦制药有限公司 The fingerprint of a kind of Yinhuang lung clearing preparation and standard finger-print thereof and application
CN107884508A (en) * 2017-04-16 2018-04-06 湖南安邦制药有限公司 The quality determining method of Yinhuang lung clearing capsule
CN107884508B (en) * 2017-04-16 2021-01-12 湖南安邦制药有限公司 Quality detection method of Yinhuang lung-clearing capsule
CN114099610A (en) * 2021-12-22 2022-03-01 湖南安邦制药股份有限公司 Application of traditional Chinese medicine composition in preparation of medicine and/or non-therapeutic reagent for preventing and treating rhinovirus diseases

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