CN1666099A - 分子探测器装置 - Google Patents

分子探测器装置 Download PDF

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Publication number
CN1666099A
CN1666099A CN03816280.6A CN03816280A CN1666099A CN 1666099 A CN1666099 A CN 1666099A CN 03816280 A CN03816280 A CN 03816280A CN 1666099 A CN1666099 A CN 1666099A
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CN
China
Prior art keywords
conductive surface
analyte
radiation
detector assembly
carrier
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Pending
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CN03816280.6A
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English (en)
Chinese (zh)
Inventor
理查德·吉尔伯特
周晓峰
布赖恩·P·艾伦
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e2v Biosensors Ltd
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e2v Technologies UK Ltd
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Publication date
Priority claimed from GBGB0215876.4A external-priority patent/GB0215876D0/en
Application filed by e2v Technologies UK Ltd filed Critical e2v Technologies UK Ltd
Publication of CN1666099A publication Critical patent/CN1666099A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • G01N21/554—Attenuated total reflection and using surface plasmons detecting the surface plasmon resonance of nanostructured metals, e.g. localised surface plasmon resonance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/651—Cuvettes therefore

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN03816280.6A 2002-07-10 2003-07-09 分子探测器装置 Pending CN1666099A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0215876.4 2002-07-10
GBGB0215876.4A GB0215876D0 (en) 2002-07-10 2002-07-10 Spectroscopy methods and devices
GB0309492.7 2003-04-25
GB0309492A GB2403796B (en) 2002-07-10 2003-04-25 Molecular detector arrangement

Publications (1)

Publication Number Publication Date
CN1666099A true CN1666099A (zh) 2005-09-07

Family

ID=30117106

Family Applications (1)

Application Number Title Priority Date Filing Date
CN03816280.6A Pending CN1666099A (zh) 2002-07-10 2003-07-09 分子探测器装置

Country Status (6)

Country Link
US (1) US20070030481A1 (https=)
EP (1) EP1552282A1 (https=)
JP (1) JP2005532563A (https=)
CN (1) CN1666099A (https=)
AU (1) AU2003260677C1 (https=)
WO (1) WO2004008120A1 (https=)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102095719A (zh) * 2010-12-30 2011-06-15 浙江工业大学 基于表面等离子共振和受激拉曼散射的光纤型传感系统
CN102680452A (zh) * 2012-05-14 2012-09-19 中央民族大学 一种集成微流控光学的双探测生化传感检测仪
CN102706835A (zh) * 2012-05-14 2012-10-03 中央民族大学 一种双探测生化传感检测仪的传感芯片及其制备方法
CN106896095A (zh) * 2017-01-11 2017-06-27 四川大学 复合表面等离子体共振及表面增强拉曼的显微成像技术
CN108037107A (zh) * 2017-12-04 2018-05-15 中国科学院长春光学精密机械与物理研究所 一种同步检测装置
CN108152275A (zh) * 2017-12-27 2018-06-12 福州大学 一种基于电化学发光体系的透明质酸酶检测方法
CN109031658A (zh) * 2017-06-12 2018-12-18 中国科学院大连化学物理研究所 一种薄型激光透射探测窗口

Families Citing this family (16)

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US7151598B2 (en) * 2003-04-04 2006-12-19 Vladimir Poponin Method and apparatus for enhanced nano-spectroscopic scanning
US7102747B2 (en) * 2004-10-13 2006-09-05 Hewlett-Packard Development Company, L.P. In situ excitation for Surface Enhanced Raman Spectroscopy
CA2586197C (en) 2004-11-04 2012-08-14 Mesophotonics Limited Metal nano-void photonic crystal for enhanced raman spectroscopy
GB0424458D0 (en) * 2004-11-04 2004-12-08 Mesophotonics Ltd Metal nano-void photonic crystal for enhanced raman spectroscopy
GB2431233A (en) * 2005-10-14 2007-04-18 E2V Tech Molecular detector arrangement
JP2007171003A (ja) 2005-12-22 2007-07-05 Fujifilm Corp 質量分析用基板並びに分析方法および装置
GB0606088D0 (en) * 2006-03-27 2006-05-03 E2V Biosensors Ltd Improved serrs substrate
US8017408B2 (en) 2007-04-27 2011-09-13 The Regents Of The University Of California Device and methods of detection of airborne agents
US20090233810A1 (en) * 2008-03-12 2009-09-17 The Mitre Corporation Multi-Modal surface plasmon polariton-raman scattering based bio-detection
KR101333482B1 (ko) * 2012-03-08 2013-11-26 단국대학교 산학협력단 표면 플라즈몬 산란 및 공명 검출에 기반한 생체 물질 측정 시스템
EP2834619A1 (en) * 2012-04-05 2015-02-11 Renishaw Diagnostics Limited A method for calibrating spectroscopy apparatus and equipment for use in the method
WO2016118812A1 (en) 2015-01-23 2016-07-28 Vanderbilt University A robust interferometer and methods of using same
US10627396B2 (en) 2016-01-29 2020-04-21 Vanderbilt University Free-solution response function interferometry
CN109313137A (zh) 2016-07-22 2019-02-05 惠普发展公司，有限责任合伙企业 衬底支撑的表面增强发光台和壳体
EP4133253A4 (en) 2020-04-07 2023-08-16 James I. Scholtz DEVICE AND METHOD FOR THE SELECTIVE DETECTION OF PATHOGENS AND/OR CHEMICALS
CN115561224B (zh) * 2022-09-27 2024-11-26 青岛科技大学 可循环利用的sers分子检测装置及其使用方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
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EP0305428A1 (en) * 1987-02-25 1989-03-08 Scientific Generics Ltd In vivo blood testing
US5266498A (en) * 1989-10-27 1993-11-30 Abbott Laboratories Ligand binding assay for an analyte using surface-enhanced scattering (SERS) signal
DE4004088A1 (de) * 1990-02-10 1991-08-14 Basf Ag Verfahren zur untersuchung physikalischer eigenschaften duenner schichten
SE9100392D0 (sv) * 1991-02-08 1991-02-08 Pharmacia Biosensor Ab A method of producing a sealing means in a microfluidic structure and a microfluidic structure comprising such sealing means
FI96800C (fi) * 1994-02-16 1996-08-26 Valtion Teknillinen Laite analyysin suorittamiseksi
US6025202A (en) * 1995-02-09 2000-02-15 The Penn State Research Foundation Self-assembled metal colloid monolayers and detection methods therewith
US6197503B1 (en) * 1997-11-26 2001-03-06 Ut-Battelle, Llc Integrated circuit biochip microsystem containing lens
US20010053521A1 (en) * 1999-09-27 2001-12-20 Kreimer David I. Amplification of analyte detection by substrates having particle structures with receptors
EP1236034A4 (en) * 1999-11-12 2006-05-03 Surromed Inc PLASMON RESONANCE SURFACE BIODETECTION
WO2001063256A1 (de) * 2000-02-22 2001-08-30 Graffinity Pharmaceutical Design Gmbh Spr-sensorsystem
US20030073139A1 (en) * 2001-09-21 2003-04-17 Kreimer David I. Devices and methods for verifying measurement of analytes by raman spectroscopy and surface plasmon resonance
US6970239B2 (en) * 2002-06-12 2005-11-29 Intel Corporation Metal coated nanocrystalline silicon as an active surface enhanced Raman spectroscopy (SERS) substrate
GB2404739B (en) * 2003-08-05 2006-04-12 E2V Tech Uk Ltd Sensor
GB2431233A (en) * 2005-10-14 2007-04-18 E2V Tech Molecular detector arrangement

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102095719A (zh) * 2010-12-30 2011-06-15 浙江工业大学 基于表面等离子共振和受激拉曼散射的光纤型传感系统
CN102680452A (zh) * 2012-05-14 2012-09-19 中央民族大学 一种集成微流控光学的双探测生化传感检测仪
CN102706835A (zh) * 2012-05-14 2012-10-03 中央民族大学 一种双探测生化传感检测仪的传感芯片及其制备方法
CN106896095A (zh) * 2017-01-11 2017-06-27 四川大学 复合表面等离子体共振及表面增强拉曼的显微成像技术
CN106896095B (zh) * 2017-01-11 2019-08-06 四川大学 复合表面等离子体共振及表面增强拉曼的显微成像技术
CN109031658A (zh) * 2017-06-12 2018-12-18 中国科学院大连化学物理研究所 一种薄型激光透射探测窗口
CN109031658B (zh) * 2017-06-12 2020-10-02 中国科学院大连化学物理研究所 一种薄型激光透射探测窗口
CN108037107A (zh) * 2017-12-04 2018-05-15 中国科学院长春光学精密机械与物理研究所 一种同步检测装置
CN108152275A (zh) * 2017-12-27 2018-06-12 福州大学 一种基于电化学发光体系的透明质酸酶检测方法

Also Published As

Publication number Publication date
WO2004008120A1 (en) 2004-01-22
AU2003260677C1 (en) 2009-03-26
AU2003260677B2 (en) 2008-11-06
AU2003260677A1 (en) 2004-02-02
EP1552282A1 (en) 2005-07-13
US20070030481A1 (en) 2007-02-08
JP2005532563A (ja) 2005-10-27

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