CN1660203A - Medication of 'Jiulong' capsule for treating gastric disease and preparation method - Google Patents
Medication of 'Jiulong' capsule for treating gastric disease and preparation method Download PDFInfo
- Publication number
- CN1660203A CN1660203A CN 200410061360 CN200410061360A CN1660203A CN 1660203 A CN1660203 A CN 1660203A CN 200410061360 CN200410061360 CN 200410061360 CN 200410061360 A CN200410061360 A CN 200410061360A CN 1660203 A CN1660203 A CN 1660203A
- Authority
- CN
- China
- Prior art keywords
- radix
- kowloon
- capsule
- cream powder
- caulis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 title claims abstract description 27
- 239000002775 capsule Substances 0.000 title claims abstract description 16
- 208000012895 Gastric disease Diseases 0.000 title claims description 9
- 229940079593 drug Drugs 0.000 title claims description 5
- 238000002360 preparation method Methods 0.000 title description 8
- 238000002156 mixing Methods 0.000 claims abstract description 10
- 238000001035 drying Methods 0.000 claims abstract 2
- 210000002784 stomach Anatomy 0.000 claims description 15
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 12
- 239000000796 flavoring agent Substances 0.000 claims description 12
- 235000019634 flavors Nutrition 0.000 claims description 12
- 239000006071 cream Substances 0.000 claims description 11
- 239000000843 powder Substances 0.000 claims description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- 229920002472 Starch Polymers 0.000 claims description 8
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 8
- 238000012856 packing Methods 0.000 claims description 8
- 235000019698 starch Nutrition 0.000 claims description 8
- 239000008107 starch Substances 0.000 claims description 8
- 208000018556 stomach disease Diseases 0.000 claims description 8
- 239000008187 granular material Substances 0.000 claims description 7
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 7
- 239000000284 extract Substances 0.000 claims description 6
- 239000000706 filtrate Substances 0.000 claims description 6
- 239000000080 wetting agent Substances 0.000 claims description 6
- 239000000126 substance Substances 0.000 claims description 5
- 241000238370 Sepia Species 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- 238000005303 weighing Methods 0.000 claims description 4
- 238000001694 spray drying Methods 0.000 claims description 3
- 239000012567 medical material Substances 0.000 claims description 2
- 208000007882 Gastritis Diseases 0.000 abstract description 5
- 208000002193 Pain Diseases 0.000 abstract description 5
- 208000023652 chronic gastritis Diseases 0.000 abstract description 5
- 208000000718 duodenal ulcer Diseases 0.000 abstract description 4
- 239000000463 material Substances 0.000 abstract description 2
- QBQNMIPDPJEZHR-UHFFFAOYSA-N 4-[(4-hydroxyphenyl)methoxymethyl]-2-[(4-hydroxyphenyl)methyl]phenol Chemical compound C1=CC(O)=CC=C1COCC1=CC=C(O)C(CC=2C=CC(O)=CC=2)=C1 QBQNMIPDPJEZHR-UHFFFAOYSA-N 0.000 abstract 2
- 244000236658 Paeonia lactiflora Species 0.000 abstract 1
- 235000008598 Paeonia lactiflora Nutrition 0.000 abstract 1
- 208000007107 Stomach Ulcer Diseases 0.000 abstract 1
- 241000330755 Tylosema fassoglense Species 0.000 abstract 1
- 235000018907 Tylosema fassoglense Nutrition 0.000 abstract 1
- 201000005917 gastric ulcer Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 6
- 206010000269 abscess Diseases 0.000 description 4
- 230000002496 gastric effect Effects 0.000 description 4
- 241000411851 herbal medicine Species 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 239000002994 raw material Substances 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 235000003143 Panax notoginseng Nutrition 0.000 description 1
- 241000180649 Panax notoginseng Species 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
A Chinese medicine 'Jiulong capsule' for treating gastrol cavity pain, chronic gastritis, gastric ulcer, duodenal ulcer, etc is prepared from 5 Chinese-medicinal materials including champion bauhinia stem, jasminerage leaf and twig, white peony root, etc through extracting, proportionally mixing, drying and loading in capsules.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of gastropathy, particularly nine flavor Chinese herbal medicine such as Caulis Bauhihiae Championii are made into capsule and are used for the treatment of medicine of gastropathy and preparation method thereof.
Back of the body border technology
Treating at present gastropathy Chinese patent medicine commonly used clinically has a lot, treatment cold-evil visitor stomach card gastric abscess, chronic gastritis WENWEISHU granule commonly used, Radix Notoginseng capsule for treating stomachache etc.; Said medicine differs from one another, and goodish effect is all arranged, but effect is often too single.
The present invention is the raw material pharmaceutical preparation made from nine flavor Chinese herbal medicine such as Caulis Bauhihiae Championii all has definite curative effect to the treatment of above-mentioned gastropathy, and especially to gastric abscess, chronic gastritis due to the cold-evil visitor stomach, the pain of stomach, duodenal ulcer has unique effect.The present invention is to be the medicament of the treatment gastropathy made of raw material with nine flavor Chinese herbal medicine such as Caulis Bauhihiae Championii, and drug quality is more easy to control, also is easy to carry out the developmental research of the modernization of Chinese medicine.Compare with other dosage form: the capsule outward appearance is bright and clean, attractive in appearance, can cover the bitterness of Chinese patent medicine discomfort, is convenient to take; And the bioavailability of medicament height, supplementary product consumption is few, is difficult for the moisture absorption, good stability.
Summary of the invention
Make a kind of capsule after the objective of the invention is to nine flavor medicinal material extract such as Caulis Bauhihiae Championii are gone out effective ingredient, this preparation can be filled up the deficiency that existing product exists, to cold-evil visitor stomach card gastric abscess, chronic gastritis, the pain of stomach, duodenal ulcer have unique curative effect.
The present invention constitutes like this:
Kowloon stomach medicament capsule agent, crude drug prescription and parts by weight are: Caulis Bauhihiae Championii 800g, Folium Et Cacumen Murrayae 330g, Radix Zanthoxyli 300g, Herba Sarcandrae 750g, Pericarpium Citri Reticulatae 250g, Radix Aucklandiae 200g, Radix Paeoniae Alba 300g, Radix et Caulis Opuntiae Dillenii 150g, Radix Glycyrrhizae 250g.
Manufacture method is: calculate with composition by weight: the dried cream powder, Pulvis Talci, soluble starch of getting Caulis Bauhihiae Championii, Folium Et Cacumen Murrayae, Radix Zanthoxyli, Herba Sarcandrae, Pericarpium Citri Reticulatae, the Radix Aucklandiae, the Radix Paeoniae Alba, Radix et Caulis Opuntiae Dillenii, Radix Glycyrrhizae nine flavor medicinal substances extracts is in 94: 1～10: 0.2～2 ratio mixing, make sepia to auburn granule, dry, encapsulated, be up to the standards, packing, promptly.
Calculate with composition by weight: the dried cream powder, Pulvis Talci, soluble starch of getting Caulis Bauhihiae Championii, Folium Et Cacumen Murrayae, Radix Zanthoxyli, Herba Sarcandrae, Pericarpium Citri Reticulatae, the Radix Aucklandiae, the Radix Paeoniae Alba, Radix et Caulis Opuntiae Dillenii, Radix Glycyrrhizae nine flavor medicinal substances extracts is in 94: 1～10: 0.2～2 ratio mixing, be that 70%～95% ethanol is made sepia to auburn granule as wetting agent with concentration, dry, encapsulated, be up to the standards, packing, promptly.
Specifically: get nine flavor medical materials such as Caulis Bauhihiae Championii, decoct with water secondary, adding for the first time 10 times of water gagings decocted 2 hours, adding for the second time 8 times of water gagings decocted 2 hours, merging filtrate filters, and filtrate is concentrated into the clear paste that relative density is 1.05～1.12 (80 ℃), spray drying (about 120 ℃ of hothouse temperature), make dried cream powder, calculate with composition by weight: get dried cream powder, Pulvis Talci, soluble starch is in 94: 1～10: 0.2～2 ratio mixings, is that 70%～95% ethanol is made wet granular as wetting agent with concentration, dry (60 ℃～70 ℃), make dried granule, encapsulated, be up to the standards, packing, promptly.
Kowloon of the present invention stomach medicament capsule is to be the medicine that raw material is made by advanced person's preparation method with nine flavor Chinese herbal medicine such as Caulis Bauhihiae Championii, compare with other technology: the formation of medicine of the present invention is simple, clear and definite, and quality is convenient to control, and the capsule of making is the Sugarless type preparation, can increase the crowd of being suitable for, capsule is the advanced preparation of improved Chinese medicine, and is with high content of technology, patient's taking convenience, mouthfeel is good, the drug bioavailability height is difficult for the moisture absorption, good stability; It is few that this product and other dosage form have been compared dose, and curative effect has the characteristics of equivalence with it, and the volume of this preparation is little, need not boiled water to take after mixing it with water, and takes, carries more convenient.
Embodiment 1:
Take by weighing Caulis Bauhihiae Championii 800g, Folium Et Cacumen Murrayae 330g, Radix Zanthoxyli 300g, Herba Sarcandrae 750g, Pericarpium Citri Reticulatae 250g, Radix Aucklandiae 200g, Radix Paeoniae Alba 300g, Radix et Caulis Opuntiae Dillenii 150g, Radix Glycyrrhizae 250g respectively.Decoct with water secondary, add 10 times of water gagings for the first time and decocted 2 hours, add 8 times of water gagings for the second time and decocted 2 hours, merging filtrate filters, and filtrate is concentrated into the clear paste that relative density is 1.05～1.12 (80 ℃), spray drying, about 120 ℃ of hothouse temperature are made dried cream powder.Calculate with composition by weight: taking by weighing dried cream powder 5000g, Pulvis Talci 53.2g, soluble starch 10.6g mixing in 94: 1: 0.2 ratios, is that 95% 50ml ethanol is made wet granular as wetting agent with concentration, dry (60 ℃～70 ℃), make 12500, be up to the standards, packing, promptly.
Embodiment 2:
Calculate with composition by weight: dried cream powder 5000g, the Pulvis Talci 266g, the soluble starch 53.2g mixing that take by weighing nine flavor medicinal substances extracts such as Caulis Bauhihiae Championii in 94: 5: 1 ratios, with concentration is that 70% ethanol 80ml makes wet granular as wetting agent, dry (60 ℃～70 ℃), make 13200, be up to the standards, packing, promptly.
The function of this product cures mainly: warming stomach for dispelling cold, regulating QI to relieve pain.Be used for cold-evil visitor stomach card gastric abscess; Chronic gastritis, the pain of stomach, duodenal ulcer.
Claims (4)
1, a kind of medicine Kowloon stomach medicament capsule for the treatment of gastropathy is characterized in that:
Crude drug prescription and parts by weight are: Caulis Bauhihiae Championii 800g, Folium Et Cacumen Murrayae 330g, Radix Zanthoxyli 300g, Herba Sarcandrae 750g, Pericarpium Citri Reticulatae 250g, Radix Aucklandiae 200g, Radix Paeoniae Alba 300g, Radix et Caulis Opuntiae Dillenii 150g, Radix Glycyrrhizae 250g.
2, a kind of manufacture method for the treatment of the medicine Kowloon stomach medicament capsule of gastropathy is characterized in that:
Calculate with composition by weight: the dried cream powder, Pulvis Talci, soluble starch of getting Caulis Bauhihiae Championii, Folium Et Cacumen Murrayae, Radix Zanthoxyli, Herba Sarcandrae, Pericarpium Citri Reticulatae, the Radix Aucklandiae, the Radix Paeoniae Alba, Radix et Caulis Opuntiae Dillenii, Radix Glycyrrhizae nine flavor medicinal substances extracts is in 94: 1～10: 0.2～2 ratio mixing, make sepia to auburn granule, dry, encapsulated, be up to the standards, packing, promptly.
3, the manufacture method of Kowloon according to claim 2 stomach medicament capsule is characterized in that:
Calculate with composition by weight: the dried cream powder, Pulvis Talci, soluble starch of getting Caulis Bauhihiae Championii, Folium Et Cacumen Murrayae, Radix Zanthoxyli, Herba Sarcandrae, Pericarpium Citri Reticulatae, the Radix Aucklandiae, the Radix Paeoniae Alba, Radix et Caulis Opuntiae Dillenii, Radix Glycyrrhizae nine flavor medicinal substances extracts is in 94: 1～10: 0.2～2 ratio mixing, be that 70%～95% ethanol is made sepia to auburn granule as wetting agent with concentration, dry, encapsulated, be up to the standards, packing, promptly.
4, manufacture method according to claim 2 or 3 described Kowloon stomach medicament capsule, it is characterized in that: above nine flavor medical materials, decoct with water secondary, add for the first time 10 times of water gagings and decocted 2 hours, add 8 times of water gagings for the second time and decocted merging filtrate 2 hours, filter, it is 1.05～1.12 clear paste that filtrate is concentrated into relative density, and spray drying is made dried cream powder, calculate with composition by weight: take by weighing dried cream powder in 94: 1～10: 0.2～2 ratios, Pulvis Talci, the soluble starch mixing, with concentration is that 70%～95% ethanol is made wet granular as wetting agent, and drying is made dried granule, encapsulated, be up to the standards, packing, promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100613609A CN100339110C (en) | 2004-12-13 | 2004-12-13 | Medication of 'Jiulong' capsule for treating gastric disease and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100613609A CN100339110C (en) | 2004-12-13 | 2004-12-13 | Medication of 'Jiulong' capsule for treating gastric disease and preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1660203A true CN1660203A (en) | 2005-08-31 |
| CN100339110C CN100339110C (en) | 2007-09-26 |
Family
ID=35009941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100613609A Active CN100339110C (en) | 2004-12-13 | 2004-12-13 | Medication of 'Jiulong' capsule for treating gastric disease and preparation method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100339110C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101926952B (en) * | 2009-06-26 | 2012-07-04 | 邹声达 | Traditional Chinese medicine for treating gastropathy |
| CN107898907A (en) * | 2017-12-29 | 2018-04-13 | 广西万德药业有限公司 | Treat capsule of acute or chronic gastritis and preparation method thereof |
| CN107998256A (en) * | 2017-12-29 | 2018-05-08 | 广西万德药业有限公司 | Treat sustained release tablets of gastritis and preparation method thereof |
| CN108096430A (en) * | 2017-12-29 | 2018-06-01 | 广西万德药业有限公司 | Chinese medicine composition containing Tupistra and preparation method thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1235636C (en) * | 2003-10-07 | 2006-01-11 | 李伟 | Kangning Stomach invigorating capsule |
-
2004
- 2004-12-13 CN CNB2004100613609A patent/CN100339110C/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101926952B (en) * | 2009-06-26 | 2012-07-04 | 邹声达 | Traditional Chinese medicine for treating gastropathy |
| CN107898907A (en) * | 2017-12-29 | 2018-04-13 | 广西万德药业有限公司 | Treat capsule of acute or chronic gastritis and preparation method thereof |
| CN107998256A (en) * | 2017-12-29 | 2018-05-08 | 广西万德药业有限公司 | Treat sustained release tablets of gastritis and preparation method thereof |
| CN108096430A (en) * | 2017-12-29 | 2018-06-01 | 广西万德药业有限公司 | Chinese medicine composition containing Tupistra and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100339110C (en) | 2007-09-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100353983C (en) | Chinese medicine preparation for reducing sugar | |
| CN101411497B (en) | Lipid-lowering pressure-reducing hypoglycemic health tea | |
| CN103041118B (en) | Composition with effects of reducing blood sugar and reducing blood lipid | |
| CN101485825A (en) | Chinese medicine capsule for treating diabetes | |
| CN106237078A (en) | A kind of nurse one's health insufficiency of the spleen Chinese medicine composition | |
| CN108713746A (en) | A kind of integration of drinking and medicinal herbs composition and its preparation method and application | |
| CN104474472B (en) | Buccal lozenge of lectuce tea and its production method with three high drop effect | |
| CN100339110C (en) | Medication of 'Jiulong' capsule for treating gastric disease and preparation method | |
| RU2442598C1 (en) | Diuretic agent | |
| CN101317983A (en) | Method for preparing capsule for nourishing Yin and suppressing Yang, discharging fire and pacifying the mind | |
| CN101317929A (en) | Method for preparing capsule for warming yang, tonifying qi, and promoting defecation | |
| CN101518630A (en) | Anti-gout traditional Chinese medical composition and preparation method thereof | |
| CN103948738A (en) | Sore throat relieving anti-inflammatory bird's nest composition and preparation method and application thereof | |
| CN103550333A (en) | Composition for appetizing and reducing blood pressure | |
| CN1054057C (en) | Tea for throat care and its preparation | |
| CN1267143C (en) | Method for preparing compound medicinal capsule and powder for nourishing yin | |
| CN107519261A (en) | A kind of Chinese medicine composition for treating leukaemia and preparation method thereof | |
| CN101317950A (en) | Method for preparing capsule for benefitting qi, nourishing blood, nourishing heart and pacifying the mind | |
| CN1247214C (en) | Hard capsule agent for treating gynaopathy and its preparing method | |
| CN102058849B (en) | Application of Tibetan medicine composite to preparing alcohol withdrawal medicines | |
| CN105267929A (en) | Micro-powder capsule for treating peptic ulcer | |
| CN100356934C (en) | Health-care food with spot-removing function | |
| CN106109839A (en) | A kind of nurse one's health insufficiency of the spleen Chinese medicine composition | |
| CN101020041A (en) | Antilipemic health product | |
| KR20090074475A (en) | Articulation therapeutic agent for chinese medicine and manufacture method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: LIU NIANDONG Free format text: FORMER OWNER: OU CHUNMIN Effective date: 20090717 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20090717 Address after: The Guangxi Zhuang Autonomous Region high tech Zone in Nanning Kede Road No. 4 Patentee after: Liu Niandong Address before: Nanning City, the Guangxi Zhuang Autonomous Region Xing Hu Lu Nan Yi Li Yi Xiang No. 8 Xinghu apartment No. 3-2-4-1 Patentee before: Ou Chunmin |
|
| DD01 | Delivery of document by public notice |
Addressee: Liu Niandong Document name: Notification to Pay the Fees |
|
| DD01 | Delivery of document by public notice | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20190703 Address after: 535008 No. 68 Anshan Road, Babu District, Hezhou City, Guangxi Zhuang Autonomous Region Patentee after: Jinji Pharmaceutical Co., Ltd. Address before: 530003 No. 4 Kede Road, Nanning High-tech Zone, Guangxi Zhuang Autonomous Region Patentee before: Liu Niandong |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20200323 Address after: 535416, Lingshan Qinzhou land Industrial Park, the Guangxi Zhuang Autonomous Region Patentee after: GUANGXI GEHONGTANG PHARMACEUTICAL Co.,Ltd. Address before: 535008 No. 68 Anshan Road, Babu District, Hezhou City, Guangxi Zhuang Autonomous Region Patentee before: Jinji Pharmaceutical Co., Ltd. |
|
| TR01 | Transfer of patent right |