CN1656230B - 丙二醇烷基或芳基醚及醚乙酸酯的酶催化拆分 - Google Patents

丙二醇烷基或芳基醚及醚乙酸酯的酶催化拆分 Download PDF

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Publication number
CN1656230B
CN1656230B CN038067668A CN03806766A CN1656230B CN 1656230 B CN1656230 B CN 1656230B CN 038067668 A CN038067668 A CN 038067668A CN 03806766 A CN03806766 A CN 03806766A CN 1656230 B CN1656230 B CN 1656230B
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reaction
matrix
enzyme
propylene glycol
ester
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Chinese (zh)
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CN1656230A (zh
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S·M·雷斯尼克
F·A·多纳特
T·C·弗兰克
T·C·塞因
P·福利
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Dr Reddys Laboratories EU Ltd
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Dr Reddys Laboratories Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
CN038067668A 2002-03-22 2003-03-21 丙二醇烷基或芳基醚及醚乙酸酯的酶催化拆分 Expired - Fee Related CN1656230B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36676702P 2002-03-22 2002-03-22
US60/366,767 2002-03-22
PCT/US2003/008941 WO2003083126A2 (en) 2002-03-22 2003-03-21 Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates

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Publication Number Publication Date
CN1656230A CN1656230A (zh) 2005-08-17
CN1656230B true CN1656230B (zh) 2010-06-23

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CN038067668A Expired - Fee Related CN1656230B (zh) 2002-03-22 2003-03-21 丙二醇烷基或芳基醚及醚乙酸酯的酶催化拆分

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US (1) US7264960B2 (enExample)
EP (1) EP1490501B1 (enExample)
JP (1) JP2005520570A (enExample)
KR (1) KR20040099348A (enExample)
CN (1) CN1656230B (enExample)
AT (1) ATE469237T1 (enExample)
AU (1) AU2003222053A1 (enExample)
DE (1) DE60332714D1 (enExample)
WO (1) WO2003083126A2 (enExample)

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Publication number Priority date Publication date Assignee Title
WO2005095629A1 (en) * 2004-03-29 2005-10-13 Dsm Ip Assets B.V. Process for the preparation of enantiomerically enriched esters and alcohols by means of azeotropically dried enzyme compositions
US7570651B2 (en) * 2004-06-16 2009-08-04 Siamack Haghighi High-performance reconfigurable interconnect for concurrent operation of multiple systems
KR100650798B1 (ko) * 2004-07-19 2006-11-27 (주)제이코통상 광학활성 카복실산의 제조방법
KR100650797B1 (ko) * 2005-12-12 2006-11-27 (주)케미코월드 광학활성 사이클로프로판 카복사미드의 제조방법
CN100427608C (zh) * 2006-11-08 2008-10-22 浙江大学 酶法拆分制备光学活性烯丙基呋喃甲醇的方法
EP2655646A4 (en) * 2010-12-20 2014-05-21 Du Pont TARGETED PERHYDROLASES
DE102011107959A1 (de) * 2011-07-20 2013-01-24 Thyssenkrupp Uhde Gmbh Herstellung von optisch reinem Propan-1,2-diol
CN114058655B (zh) * 2021-11-30 2023-08-29 青岛科技大学 一种酶-化学一锅法合成(r)-乙酰胺基苯丙醇的方法
WO2024021261A1 (zh) * 2022-07-29 2024-02-01 上海皓元医药股份有限公司 一种艾日布林中间体的制备方法

Family Cites Families (3)

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Publication number Priority date Publication date Assignee Title
US5541080A (en) 1991-11-01 1996-07-30 Wisconsin Alumni Research Fdn. Method for preparing L-alpha-amino acids
JP3874035B2 (ja) * 1996-06-26 2007-01-31 三菱瓦斯化学株式会社 光学活性２級アルコールの製造法
JP2000063312A (ja) * 1998-08-17 2000-02-29 Mitsubishi Gas Chem Co Inc 光学活性２級アルコール及びその製造法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Baumann M et al.Rapid screening of hydrolases for the enantioselectiveconversion of difficult-to-resolve substrates.Tetrahedron: Asymmetry11 (23).2000,11((23)),4781-4790.
Baumann M et al.Rapid screening of hydrolases for the enantioselectiveconversion of difficult-to-resolve substrates.Tetrahedron: Asymmetry11 (23).2000,11((23)),4781-4790. *

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Publication number Publication date
KR20040099348A (ko) 2004-11-26
EP1490501A2 (en) 2004-12-29
US20050026260A1 (en) 2005-02-03
WO2003083126A3 (en) 2004-01-22
US7264960B2 (en) 2007-09-04
ATE469237T1 (de) 2010-06-15
CN1656230A (zh) 2005-08-17
EP1490501B1 (en) 2010-05-26
WO2003083126A8 (en) 2005-03-17
WO2003083126A2 (en) 2003-10-09
AU2003222053A1 (en) 2003-10-13
DE60332714D1 (de) 2010-07-08
JP2005520570A (ja) 2005-07-14

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