CN1633877A - Coating type granula enzyme production process - Google Patents
Coating type granula enzyme production process Download PDFInfo
- Publication number
- CN1633877A CN1633877A CNA2004100612875A CN200410061287A CN1633877A CN 1633877 A CN1633877 A CN 1633877A CN A2004100612875 A CNA2004100612875 A CN A2004100612875A CN 200410061287 A CN200410061287 A CN 200410061287A CN 1633877 A CN1633877 A CN 1633877A
- Authority
- CN
- China
- Prior art keywords
- starch
- enzyme
- flour
- granzyme
- edible
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000004190 Enzymes Human genes 0.000 title claims abstract description 29
- 108090000790 Enzymes Proteins 0.000 title claims abstract description 29
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 10
- 239000011248 coating agent Substances 0.000 title abstract 3
- 238000000576 coating method Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 claims abstract description 32
- 229920002472 Starch Polymers 0.000 claims abstract description 18
- 239000008107 starch Substances 0.000 claims abstract description 18
- 235000019698 starch Nutrition 0.000 claims abstract description 18
- 238000001035 drying Methods 0.000 claims abstract description 14
- 235000013312 flour Nutrition 0.000 claims abstract description 11
- 239000000853 adhesive Substances 0.000 claims abstract description 10
- 230000001070 adhesive effect Effects 0.000 claims abstract description 10
- 238000002156 mixing Methods 0.000 claims abstract description 7
- 238000001125 extrusion Methods 0.000 claims abstract description 6
- 102000001398 Granzyme Human genes 0.000 claims description 17
- 108060005986 Granzyme Proteins 0.000 claims description 17
- 239000007921 spray Substances 0.000 claims description 9
- 239000008187 granular material Substances 0.000 claims description 6
- 239000002002 slurry Substances 0.000 claims description 6
- 239000001856 Ethyl cellulose Substances 0.000 claims description 2
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims description 2
- 229920001249 ethyl cellulose Polymers 0.000 claims description 2
- 235000019325 ethyl cellulose Nutrition 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 238000005507 spraying Methods 0.000 abstract 2
- 238000009835 boiling Methods 0.000 abstract 1
- 238000007873 sieving Methods 0.000 abstract 1
- 229940088598 enzyme Drugs 0.000 description 22
- 230000000694 effects Effects 0.000 description 7
- 239000000654 additive Substances 0.000 description 4
- 102000035101 Aspartic proteases Human genes 0.000 description 3
- 108091005502 Aspartic proteases Proteins 0.000 description 3
- 239000004382 Amylase Substances 0.000 description 2
- 108010065511 Amylases Proteins 0.000 description 2
- 102000013142 Amylases Human genes 0.000 description 2
- 108010001682 Dextranase Proteins 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 235000019418 amylase Nutrition 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 108010011619 6-Phytase Proteins 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 108010059820 Polygalacturonase Proteins 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000003674 animal food additive Substances 0.000 description 1
- 238000005842 biochemical reaction Methods 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 230000009193 crawling Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 239000003640 drug residue Substances 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 238000012407 engineering method Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 108010026195 glycanase Proteins 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 229940085127 phytase Drugs 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Landscapes
- Fodder In General (AREA)
Abstract
Disclosed is a coating type granula enzyme production process which comprises mixing planned fodder enzymes, starch and flour as carrier, edible adhesive for increasing adhesion, charging starch plasm of predetermined concentration (5-15%), granulating through wet process (or extrusion method), boiling for drying, starting spraying system at the later stage of drying, coating with spraying method, sieving to obtain 40-120 mesh circular coated granulated enzymes.
Description
Technical field
The present invention relates to a kind of production technique of fodder additives, a kind of specifically granzyme production technique.
Technical background
Enzyme is a kind of active substance that organism produces, and is the catalyzer of various biochemical reactions in the body, and the digestion of various nutritive substances, absorption and utilization all must rely on the effect of enzyme.Enzyme has characteristics such as specificity, high efficiency and specificity.The enzyme class of having found at present has several thousand kinds, and that can manually produce has kind more than 300, an existing kind more than 20 of widespread use in fodder industry.Have active enzyme product by the biological engineering method generation, be called zymin.Zymin as fodder additives mainly contains function enzyme and nutrition enzyme, zymin is a kind of environmental protection and green feed additive owing to can effectively improve detrimentally affects such as efficiency of feed utilization, saving feed resource, the drug residue that has no side effect, do not exist medicated premix and generation resistance.Scientific knowledge zymin and rational Application zymin class fodder additives have very big effect to action effect and the raising quality of the fodder level that improves zymin.Weighing the quality level of zymin and the foundation of action effect, mainly is the kind and the content of enzyme, the activity of enzyme and stable.In recent years, zymin was used widely at feedstuff industry.But normally used zymin is a powdery on the market, and is mobile, dispersed, temperature tolerance is all undesirable, therefore in the interpolation process, easily produce dust, consumption is big, and is difficult for being mixed evenly, causes the activity and the stability of enzyme in the feed that adds zymin all undesirable.This is that enzyme is a protein because the main component of zymin is an organized enzyme, and is responsive to heat, light, acid etc., and feed in process of production, because the influence of pulverizing, premix, granulation and other additives all may make the active impaired even sex change of enzyme.
Summary of the invention
The technical problem to be solved in the present invention is to provide the production technique of a kind of flowability, dispersiveness, coated granzyme that temperature tolerance is good.
The technical scheme that the present invention solves the problems of the technologies described above is: a kind of coated granzyme production technique, the fodder enzyme that various plans are added (comprises pure enzyme or prozyme, as zytase, the glycanase of crawling, α-Dian Fenmei, aspartic protease, phytase, the single pure enzyme of polygalacturonase or wherein two kinds and multiple prozyme) and as the starch and the flour of carrier, and the edible adhesive thorough mixing that increases degree of adhesion, the starch slurry that adds normality (5-15%), granulate by wet method (or extruding), fluidized drying, start fog system at the later stage of drying, wrap quilt with spray method, obtain circular coated granzyme of 40-120 day through sub-sieve.
Above-mentioned consumption weight part edible or feeding enzyme, starch, flour and edible adhesive is: edible or feeding enzyme 35-45, starch 35-62, flour 0-25, edible adhesive 0.5-1.5;
Above-mentioned spray method be exactly the existing conventional bag by spray method, promptly soak the capsulating material ethyl cellulose and carboxymethyl cellulose is sprayed with edible ethanol.
The inventive method production technique is simple, and stability is high, and its productive rate height reaches 90～95%, and the flowability of its coated granzyme, dispersiveness, temperature tolerance are good.The inventive method is suitable for the bag quilt of all feeding enzymes.Grain number of the present invention reaches 6500-9000 grain/g, can guarantee in the interpolation journey of feed granulating, and every feed can contain 5-6 granzyme.Can reduce and control enzyme preparation amount effectively, the activity stable and enzyme of enzyme content is without prejudice in the feeds product of assurance interpolation zymin.
Embodiment
Embodiment 1:(aquatic product feed adds granzyme) zytase 35kg, starch 35kg, flour 17kg and edible adhesive (Tsing-Hua University's sunlight) 0.5kg thorough mixing is even, add concentration then and be 15% starch slurry, by wet method or extrusion process granulate, fluidized drying, with spray method bag quilt, sub-sieve, make 80-120 order coated granzyme at the later stage of drying.
Embodiment 2:(bird feed adds granzyme) zytase 25kg, dextranase 10kg, amylase 5kg, aspartic protease 5kg, starch 30kg, flour 25kg thorough mixing be even, add concentration then and be 5% starch slurry, by wet method or extrusion process granulate, fluidized drying, in drying process,, make 40-120 order coated granzyme with spray method bag quilt, sub-sieve.
Embodiment 3:(pig's feed adds granzyme) zytase 40kg, starch 37.5kg, flour 20kg and edible adhesive 1.5kg thorough mixing is even, add concentration then and be 20% starch slurry, by wet method or extrusion process granulate, fluidized drying, in drying process,, make 40-120 order coated granzyme with spray method bag quilt, sub-sieve.
Embodiment 4:(ruminates the type animal-feed and adds granzyme) zytase 20kg, dextranase 5kg, aspartic protease 10kg, amylase 5kg, starch 35kg, flour 25kg and edible adhesive 0.5kg thorough mixing is even, add concentration then and be 15% starch slurry, by wet method or extrusion process granulate, fluidized drying, in drying process,, make 40-120 order coated granzyme with spray method bag quilt, sub-sieve.
Claims (1)
1, a kind of production technique of granzyme, it is characterized in that eating or feeding enzyme, starch, flour and edible adhesive thorough mixing even, add the starch slurry that concentration is 5-15% then, by wet method or extrusion process granulate, fluidized drying, with spray method bag quilt, sub-sieve, make 40-120 order coated granzyme at the later stage of drying;
Above-mentioned consumption weight part edible or feeding enzyme, starch, flour and edible adhesive is: edible or feeding enzyme 35-45, starch 35-62, flour 0-25, edible adhesive 0.5-1.5;
Used capsulating material is an ethyl cellulose in the above-mentioned spray method.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100612875A CN100542415C (en) | 2004-12-07 | 2004-12-07 | The coated granzyme production technology |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100612875A CN100542415C (en) | 2004-12-07 | 2004-12-07 | The coated granzyme production technology |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1633877A true CN1633877A (en) | 2005-07-06 |
| CN100542415C CN100542415C (en) | 2009-09-23 |
Family
ID=34846314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100612875A Active CN100542415C (en) | 2004-12-07 | 2004-12-07 | The coated granzyme production technology |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100542415C (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102362696A (en) * | 2011-08-23 | 2012-02-29 | 上海欧耐施生物技术有限公司 | Envelope production process for granzyme for temperature-resistant feed |
| CN107080053A (en) * | 2017-03-21 | 2017-08-22 | 四川新华扬山野生物有限公司 | A kind of heat-resistance type coating bioactive substance and preparation method thereof |
-
2004
- 2004-12-07 CN CNB2004100612875A patent/CN100542415C/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102362696A (en) * | 2011-08-23 | 2012-02-29 | 上海欧耐施生物技术有限公司 | Envelope production process for granzyme for temperature-resistant feed |
| CN102362696B (en) * | 2011-08-23 | 2013-10-16 | 上海欧耐施生物技术有限公司 | Envelope production process for granzyme for temperature-resistant feed |
| CN107080053A (en) * | 2017-03-21 | 2017-08-22 | 四川新华扬山野生物有限公司 | A kind of heat-resistance type coating bioactive substance and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100542415C (en) | 2009-09-23 |
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Owner name: HU'NAN QIU ZEYOU PATENT STRATEGIC PLANNING CO., LT Free format text: FORMER OWNER: QIU ZEYOU Effective date: 20101028 |
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Free format text: CORRECT: ADDRESS; FROM: 410011 28/F, SHUNTIANCHENG, NO.59, SECTION 2 OF FURONG MIDDLE ROAD, CHANGSHA CITY, HU'NAN PROVINCE TO: 410205 JUXING INDUSTRY BASE, NO.8, LUJING ROAD, CHANGSHA HIGH-TECH. DEVELOPMENT ZONE, YUELU DISTRICT, CHANGSHA CITY, HU'NAN PROVINCE |
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Effective date of registration: 20101104 Address after: 430074 Hubei city of Wuhan province Kuanshan East Lake development zone two Road No. 1 International Business Center Patentee after: Wuhan Sunhy Biology Co., Ltd. Address before: 430074 Hubei city of Wuhan province Kuanshan East Lake development zone two Road No. 1 International Business Center Patentee before: Xinhuayang Biological Co., Ltd., Wuhan |
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Address after: 430074 Hubei city of Wuhan province East Lake New Technology Development Zone, Ling Shan Road No. 5 Patentee after: Wuhan Sunhy Biology Co., Ltd. Address before: 430074 Hubei city of Wuhan province Kuanshan East Lake development zone two Road No. 1 International Business Center Patentee before: Wuhan Sunhy Biology Co., Ltd. |
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Address after: No.98, guangguba Road, Donghu New Technology Development Zone, Wuhan City, Hubei Province Patentee after: Wuhan Sunhy Biology Co., Ltd. Address before: 430074, No. 5, Ling Nan Road, East Lake New Technology Development Zone, Wuhan, Hubei, China Patentee before: Wuhan Sunhy Biology Co., Ltd. |
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