CN1623598A - Volatile extraction for promoting falling asleep and improving sleep quality and its product for external use - Google Patents

Volatile extraction for promoting falling asleep and improving sleep quality and its product for external use Download PDF

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CN1623598A
CN1623598A CN 200410026278 CN200410026278A CN1623598A CN 1623598 A CN1623598 A CN 1623598A CN 200410026278 CN200410026278 CN 200410026278 CN 200410026278 A CN200410026278 A CN 200410026278A CN 1623598 A CN1623598 A CN 1623598A
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sleep quality
rhizoma
promotes
fall asleep
volatile
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CN1268388C (en
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陈瑞真
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Abstract

A volatile refined oil for hypnotizing and improving sleep quality is prepared from grass-leaved sweetflag rhizome (60-90 wt.%) and ginger (10-40 wt.%). Its advantages are high effect, and no poison and irritation.

Description

A kind of volatile spirits and externally applied product thereof that promotes to fall asleep, improve sleep quality
Affiliated technical field:
The present invention relates to the external use health product technical field, be specifically related to a kind of volatile spirits and externally applied product thereof that promotes to fall asleep, improve sleep quality.
Background technology:
The 21 century enemy of human health maximum is " insomnia ", modern society's work rhythm anxiety, and people's pressure is big, and the sleep disorder problem is more and more outstanding, and insomnia is a kind of commonly encountered diseases, frequently-occurring disease, and the whole world has people's existence sleep disorder in various degree of 27% approximately.For this reason, UNESCO is decided to be March 21 in every year " international sleep day ", this shows that sleep is how important to the whole mankind's health.At present Cure for insomnia, what improve sleep quality generally is the oral medicine and the injection drug thereof of calming soporific class, this class medicine produces at last and accumulates addiction if prolonged application can produce habituation, dependency, has than significant side effects.
Summary of the invention:
The present invention will overcome the shortcoming that there is apparent side effect in prior art.
For overcoming the shortcoming that prior art exists, technical scheme of the present invention is: a kind of volatile spirits that promotes to fall asleep, improve sleep quality, form Rhizoma Acori Graminei 60~90% by the quintessence oil of following raw material by weight percentage; Rhizoma Zingiberis Recens 10~40%.
The preferable range of such scheme is: Rhizoma Acori Graminei 80~90%; Rhizoma Zingiberis Recens 10~20%.
Such scheme also comprises the quintessence oil of Rhizoma et radix valerianae, and the Rhizoma et radix valerianae consumption is 6~15% of described Rhizoma Acori Graminei and a Rhizoma Zingiberis Recens raw material gross weight.
The Rhizoma et radix valerianae consumption is 10~15% of described Rhizoma Acori Graminei and a Rhizoma Zingiberis Recens raw material gross weight in the such scheme.
Such scheme also comprises Semen Ziziphi Spinosae, Semen Platycladi, the Radix Aucklandiae, Cacumen Platycladi, five kinds of raw materials of Folium Perillae, and the consumption of these five kinds of raw materials is respectively 3~8% of described Rhizoma Acori Graminei and Rhizoma Zingiberis Recens raw material gross weight.
The consumption of five kinds of raw materials is respectively 6~8% of described Rhizoma Acori Graminei and Rhizoma Zingiberis Recens raw material gross weight in the such scheme.
Adding excipient in the above-mentioned volatile spirits can be prepared into cream, frost, liniment, spray, perfume, floral water, air freshener, bath agent, bathe with externally applied products such as shampoo, foot-bath agent (oil), toothpaste, chewing gum.
Above-mentioned excipient is one or more in any common excipient such as stearic acid, stearyl alcohol, monoglyceride, liquid paraffin, dehydrated alcohol, 95% ethanol, lanoline, vaseline, triethanolamine, propylene glycol, glycerol, sodium lauryl sulfate, cellulose gum, superfine Pelvetia siliquosa Tseng et C. F. Chang, lauryl alcohol sulphuric acid tri ethanol ammonium salt (40% aqueous solution), polyoxyethylene (3) sodium lauryl ether sulphates (30 aqueous solution), lauroyl diethanol ammonium, glycerol monopalmitate, tween 80.
Side of the present invention separates: Rhizoma Acori Graminei and Rhizoma Zingiberis Recens are altogether for monarch drug: Rhizoma et radix valerianae can strengthen the merit of principal agent, can make widely known the gesture of principal agent, and cooperates monarch drug, realizes promoting sleeping, tranquillizing and allaying excitement and improves the effect of sleep quality, is ministerial drug; And Semen Ziziphi Spinosae, Semen Platycladi, the Radix Aucklandiae, Cacumen Platycladi, Folium Perillae etc. make the health care of product more perfect, make for assistant altogether.
Compared with prior art, advantage of the present invention is:
1, easy to use: this product is the mixture of volatile essential oil, uses very convenient at present as volatilizable quintessence oil.Various externally applied products with this volatile spirits preparation use also very convenient simultaneously, unguentum wherein in use can be in conjunction with the traditional massage sleeping method of the traditional Chinese medical science, by referring to that the cave massage combines microcirculation improvement with drug osmotic, regulate cerebral cortex function and vegetative nerve function system, thereby reach tranquillizing and allaying excitement, improve the health care of sleeping, it is extremely convenient to use.
2, safe and reliable, good health care effect: the present invention carries out prescription according to the Chinese medicine nature,taste and action, and nontoxic, nonirritant, no sensitization are compared with the oral medicine and the injection drug thereof of calming soporific class, and no addiction overcomes the feared state of mind of user to endo-medicine; Promote sleeping, tranquillizing and allaying excitement and improve sleep quality, prolong sleep time, reduce the number of times of awakening every night, increase a day sleep total amount, improve insomnia; To the poor sleep person, also has functions of prevention and health care.
3, production technology is simple, easy to prepare: extracts essential oil itself is a known technology, inventive point of the present invention is the mixture of quintessence oil, therefore it is easy to prepare, also is to continue to use traditional manufacturing process with quintessence oil as the various externally applied products that base stock prepares simultaneously.
The specific embodiment:
Preparation technology of the present invention adopts plants essential oil extraction process commonly used: Chinese crude drug is pulverized with Chinese medicine grinder, added then that water distills or steam distillation, its distillate is carried out oil-water separation or extraction and obtain volatile essential oil.
The invention will be further described below in conjunction with specific embodiment.
Embodiment 1: a kind of volatile spirits that promotes to fall asleep, improve sleep quality, form Rhizoma Acori Graminei 60% by the quintessence oil of following raw material by weight percentage; Rhizoma Zingiberis Recens 40%.
During preparation, the Rhizoma Zingiberis Recens raw material one of the Rhizoma Acori Graminei of the 6Kg that takes by weighing by weight and 4Kg is reinstated Chinese medicine grinder pulverize, add water then and distill, distillate is carried out ethyl acetate extraction and obtains volatile essential oil.
Embodiment 2: a kind of volatile spirits that promotes to fall asleep, improve sleep quality, form Rhizoma Acori Graminei 80% by the quintessence oil of following raw material by weight percentage; Rhizoma Zingiberis Recens 20%.
During preparation, the Rhizoma Acori Graminei of the 8Kg that takes by weighing by weight and the Rhizoma Zingiberis Recens raw material of 2Kg are pulverized with Chinese medicine grinder respectively, carried out steam distillation after the mixing, the distillate condensation obtains volatile essential oil after oil water separator separates.
Embodiment 3: a kind of volatile spirits that promotes to fall asleep, improve sleep quality, its quintessence oil by following raw material is by weight percentage formed, Rhizoma Acori Graminei 80%, Rhizoma Zingiberis Recens 20%, also comprise Rhizoma et radix valerianae, the Rhizoma et radix valerianae consumption is 8% of described Rhizoma Acori Graminei and a Rhizoma Zingiberis Recens raw material gross weight.
During preparation, the Rhizoma Acori Graminei of the 8Kg that takes by weighing by weight, the Rhizoma Zingiberis Recens of 2Kg and the Rhizoma et radix valerianae raw material of 0.8Kg are pulverized with Chinese medicine grinder respectively, added water after the mixing and distill, distillate is extracted and obtains volatile essential oil.
Embodiment 4: a kind of volatile spirits that promotes to fall asleep, improve sleep quality, quintessence oil by following raw material is by weight percentage formed, Rhizoma Acori Graminei 90%, Rhizoma Zingiberis Recens 10%, also comprise Rhizoma et radix valerianae, the Rhizoma et radix valerianae consumption is 12% of described Rhizoma Acori Graminei and a Rhizoma Zingiberis Recens raw material gross weight.
During preparation, the Rhizoma Acori Graminei of the 8Kg that takes by weighing by weight, the Rhizoma Zingiberis Recens of 2Kg and the Rhizoma et radix valerianae raw material of 1.2Kg are pulverized with Chinese medicine grinder respectively, added water then respectively and distill, distillate is extracted and obtains volatile essential oil.
Embodiment 5: a kind of volatile spirits that promotes to fall asleep, improve sleep quality, quintessence oil by following raw material is by weight percentage formed, Rhizoma Acori Graminei 80%, Rhizoma Zingiberis Recens 20%, also comprise Rhizoma et radix valerianae, Semen Ziziphi Spinosae, Semen Platycladi, the Radix Aucklandiae, Cacumen Platycladi and Folium Perillae, the Rhizoma et radix valerianae consumption is 10% of described Rhizoma Acori Graminei and a Rhizoma Zingiberis Recens raw material gross weight, the consumption of Semen Ziziphi Spinosae, the Radix Aucklandiae is respectively 3% of Rhizoma Acori Graminei and Rhizoma Zingiberis Recens raw material gross weight, and the consumption of Semen Platycladi, Cacumen Platycladi and Folium Perillae is respectively 4% of Rhizoma Acori Graminei and Rhizoma Zingiberis Recens raw material gross weight.
During preparation, the Rhizoma Acori Graminei of the 8Kg that takes by weighing by weight, the Rhizoma Zingiberis Recens of 2Kg, Rhizoma et radix valerianae, 0.3Kg Semen Ziziphi Spinosae, the 0.3Kg Radix Aucklandiae, 0.4Kg Semen Platycladi, 0.4Kg Cacumen Platycladi and the 0.4Kg Folium Perillae raw material of 1Kg are pulverized with Chinese medicine grinder respectively, add water after the mixing and distill, the distillate condensation obtains volatile essential oil after oil water separator separates.
Embodiment 6: a kind of volatile spirits that promotes to fall asleep, improve sleep quality, quintessence oil by following raw material is by weight percentage formed, Rhizoma Acori Graminei 86%, Rhizoma Zingiberis Recens 14%, also comprise Rhizoma et radix valerianae, Semen Ziziphi Spinosae, Semen Platycladi, the Radix Aucklandiae, Cacumen Platycladi and Folium Perillae, the Rhizoma et radix valerianae consumption is 14% of described Rhizoma Acori Graminei and a Rhizoma Zingiberis Recens raw material gross weight, the consumption of Semen Ziziphi Spinosae, the Radix Aucklandiae is respectively 7% of Rhizoma Acori Graminei and Rhizoma Zingiberis Recens raw material gross weight, and the consumption of Semen Platycladi, Cacumen Platycladi and Folium Perillae is respectively 7.5% of Rhizoma Acori Graminei and Rhizoma Zingiberis Recens raw material gross weight.
During preparation, the Rhizoma Acori Graminei of the 8.6Kg that takes by weighing by weight, the Rhizoma Zingiberis Recens of 1.4Kg, Rhizoma et radix valerianae, 0.7Kg Semen Ziziphi Spinosae, the 0.7Kg Radix Aucklandiae, 0.75Kg Semen Platycladi, 0.75Kg Cacumen Platycladi and the 0.75Kg Folium Perillae raw material of 1.4Kg are pulverized with Chinese medicine grinder respectively, add water after the mixing and distill, distillate is extracted and obtain volatile essential oil.
Volatile spirits among the embodiment 1~6 distributes in air by quintessence oil Perfume burner commonly used, can play the effect that promotes to fall asleep, improve sleep quality after entering human body through respiratory tract; Perhaps it is directly put on the acupuncture point, enter onset behind the human body by skin absorbs and respiratory tract.Wherein, the scheme with embodiment 6 is good.
Be that the externally applied product that main material prepares is described to above-mentioned volatile spirits below, further specify the health-care effect that volatile spirits possesses.
Embodiment 1: the external-applied ointment that promotes to fall asleep, improve sleep quality
Prescription 1:(by weight percentage)
Liquid paraffin 15% dehydrated alcohol 15% lanoline 55%
Volatile spirits 10% Percutaneous absorption enhancer, antiseptic are an amount of
Prescription 2:(by weight percentage)
Liquid paraffin 20% dehydrated alcohol 10% lanoline 60%
Volatile spirits 8% Percutaneous absorption enhancer, antiseptic are an amount of
The production method of prescription 1 and prescription 2 is: earlier liquid paraffin, lanoline are heated to 65~80 ℃ of fusings in water-bath during production, wait cold slightly back to add dehydrated alcohol, volatile spirits, stir, place cooling, can pack after waiting to solidify.
Prescription 3:A component (by weight percentage)
Stearic acid 20% lanoline 8% white vaseline 8%
Volatile spirits 10%
B component (by weight percentage)
Glycerol 10% tween 80 2% deionized water 40%
Percutaneous absorption enhancer, antiseptic 2%
Production method: earlier A, B two components are heated 70~85 ℃ of fusings respectively in water-bath, then the B component is poured in the A component under high-speed stirred, stir, get final product packaging product after cooling.
Product in the prescription 3 is entrusted the processing of Xuzhou Xi'an branch company of bright De Chun Bioceuticals Inc., and send the disease prevention and control center, Shaanxi Province to detect.Product is faint yellow unguentum, contain volatile spirits 10g in the 100g ointment, the detection conclusion shows: 1, product belongs to " actual nontoxic level ", acute skin irritation belongs to nonirritant, no sensitization, 2, on its effect, show, be subjected to examination group mice autonomic activities number of times and the apparent in view minimizing of negative control group, and difference has highly significant (P<0.01), and product has tangible sedation; All obviously increased than the blank group by the fine motion of examination group, vein bore, and difference has highly significant (P<0.01), product has the effect of tangible microcirculation improvement.Concrete experimentation and result are as follows.
The test of mice autonomic activities is as follows:
1, material and method:
1.1 tried thing: be faint yellow unguentum
1.2 animal: provide 20 of Kunming mouses by The Fourth Military Medical University's Experimental Animal Center, body weight 18~22g, male, secondary animal (the moving card of doctor word 08-013 number), feedstuff, bedding and padding derive from Xi'an Communications University's Experimental Animal Center.
1.3 animal housing's environment: the Animal House quality certification number is moving word 08-32 number of doctor, temperature 22 ℃~24 ' C, humidity 45~55%.
1.4 instrument: mice autonomic activities calculating instrument.
1.5 method: 20 mices are divided into 2 groups at random, negative control group and organized by examination, 10 every group.
Tried thing 0.5g to be coated with by every mouse web portion of examination group and Yongquan acupoint every day before the test, the negative control group mice is coated with distilled water, directly put into mice autonomic activities calculating instrument after the negative control group mice being coated with distilled water 15min in the 7th day, adapt to after 5 minutes, survey mice autonomic activities number of times in 10 minutes.After be coated with by examination group mice to be tried thing 15min, test in the same way.Relatively be subjected to examination group and negative control group difference.Experimental data is handled in the t check.
2, result:
The group number of animals Mice autonomic activities number of times in 10 minutes
(only) X ± S P value
Negative control group 10 288.0 ± 41.1
Be subjected to examination to organize 10 152.1 ± 39.6<0.01
3, conclusion
Be subjected to examination group mice autonomic activities number of times and the apparent in view minimizing of negative control group, and difference there is highly significant (p<0.01), can thinks that product has sedation.
The test of mice microcirculation is as follows:
1, material and method
1.1 tried thing: be faint yellow unguentum
1.2 laboratory animal: provide 30 of Kunming kind white mice by Xi-an No.4 Military Medical Univ.'s Experimental Animal Center, female,
Body weight 18~22g, secondary animal (the moving card of doctor word 08-013 number).Feedstuff, bedding and padding are by Xi'an Communications University
The medical college Experimental Animal Center provides.
1.3 animal housing's environment: temperature: 24-26 ℃, relative humidity: 50%-55%, the Animal House quality certification number: moving word 08-32 number of doctor.
1.4 reagent: pentobarbital sodium, last sea-run know that the chemical plant produces, and it is standby to be made into 1% concentration; Epinephrine, it is standby to be made into 0.1% concentration; QIZHENG XIAOTONG TIE, Tibet Linzhi's Qizheng Tibetan Medicine factory provides.
1.5 only tried agent amount: 0.5g/.
1.6 method: 30 mices, be divided into 3 groups at random, 10 every group, the blank group is not done special handling; The every Mus auris dextra of positive controls is given QIZHENG XIAOTONG TIE cream; Be subjected to examination to organize every Mus auris dextra to being tried thing.Pneumoretroperitoneum was injected 1% pentobarbital sodium 0.1ml/10g.bw anesthetized animal in 15 minutes, and tail vein injection 0.1% epinephrine 0.1ml/log.bw subsequently observes mouse right ear fine motion vein bore (μ m) and diameter and be the capillary vessel number in the 0.2mm scope immediately.Experimental data is handled in the t check.
2, result:
Group dosage number of animals Arteriole bore (μ m) venule bore (μ m) capillary vessel number (individual)
(g/ only) (only) X ± S P value X ± S P value X ± S P value
Blank group 10 12.4 ± 3.9 74.8 ± 9.7 1.4 ± 0.7
Be subjected to examination to organize 0.5 10 20.8 ± 5.0<0.01 108.4 ± 9.8<0.01 1.9 ± 0.7>0.05
Positive controls 0.5 10 39.8 ± 5.5<0.01 133.0 ± 17.7<0.01 3.3 ± 1.0<0.01
3, conclusion:
All obviously increased than the blank group by the fine motion of examination group, vein bore, and difference has highly significant (P<0.01), illustrate that this product has the effect of microcirculation improvement.
This product human body suggestion use amount is 0.5~1.5g.
Volatile spirits in this product is to finish with the scheme preparation of embodiment 6, find out that from compatibility having only volatile spirits in the product is Main Ingredients and Appearance, other composition is conventional excipients, therefore it is crucial to illustrate that volatile spirits plays a part, and it is the basis of product generation effect.
Embodiment 2: the externally-applied liniment that promotes to fall asleep, improve sleep quality
Prescription: (by weight percentage)
Liquid paraffin 75% glycerol 8% dehydrated alcohol 10%
Volatile spirits 5% Percutaneous absorption enhancer is an amount of
Production method: after above-mentioned former, adjuvant mixed, in water-bath suitably heating so that mix homogeneously can pack after the cooling.
Embodiment 3: the externally applied spray that promotes to fall asleep, improve sleep quality
Prescription: (by weight percentage)
Dehydrated alcohol 80% glycerol 5% liquid paraffin 8%
Volatile spirits 6% Percutaneous absorption enhancer is an amount of
Production method: after above-mentioned former, adjuvant mixed, in water-bath suitably heating so that mix homogeneously can pack after the cooling.
Using method: with said external cream, liniment, spray among the embodiment 1~3 spread upon the sun, sleep peacefully, on the acupuncture point such as wind pond, Shenmen, Shenque, spring, massaged 15~30 minutes with finger, each consumption is about 0.5~1.5g, impel medicinal volatile spirits composition Transdermal absorption and allow it volatilize naturally by massage, reach promotion by the respiratory system absorption and fall asleep, improve the sleep quality effect in indoor.
Embodiment 4: the external perfume, the floral water that promote to fall asleep, improve sleep quality
Prescription: (by weight percentage)
95% ethanol, 75% volatile spirits, 5% essence 3%
Antiseptic, pigment appropriate amount of deionized water add to 100
Production method: add medicinal volatile spirits in ethanol, essence, antiseptic etc. makes it dissolving, adds the deionized water dilution again, and a few days after-filtration is placed in sealing in the cool, adds pure dissolubility pigment as required and gets final product.
Using method: after perfume, floral water be sprinkled upon ear, wrist, oxter, the head of a quilt to be to build the abnormal smells from the patient of the suitable sleep of fragrance, the composition that makes these volatile spiritss is by the Respiratory Regulation nervus centralis, impel the insomniac sleeping, reach the effect that promotes to fall asleep, improve sleep quality with this.
Embodiment 5: the air freshener (aerosol-type) that promotes to fall asleep, improve sleep quality
Prescription: (by weight percentage)
95% ethanol, 60% volatile spirits, 8% essence 2%
Propellant (F11/F12,50: 50) 30%
Production method: after above-mentioned former, adjuvant fully mixed, load in pressurized tank and get final product.
Embodiment 6: promote to fall asleep, improve sleep quality air freshener (solid gel type)
Prescription: (by weight percentage)
Deionized water 85% propylene glycol 0.5% cellulose gum 0.5%
Superfine Pelvetia siliquosa Tseng et C. F. Chang 2% potassium chloride 1% volatile spirits 5%
Emulsifying agent 2% essence 3% colorant, antiseptic are an amount of
Production method: earlier cellulose gum, superfine Pelvetia siliquosa Tseng et C. F. Chang, potassium chloride are added the dissolving of water heated and stirred, add propylene glycol, emulsifying agent, colorant successively and treat uniform mixing, cold slightly back adds volatile spirits, essence fully stirs, cools off the formation gel, packs finished product.
Using method: air freshener sprayed or be placed on the volatile spirits composition is volatilized naturally in indoor, to build the abnormal smells from the patient of the suitable sleep of fragrance, smell the abnormal smells from the patient of these medicinal volatile spiritss, the insomniac just is easy to fall asleep, and reaches the effect that promotes to fall asleep, improve sleep quality with this.
Embodiment 7: promote to fall asleep, improve the sleep quality external-use bathing lotion, bathe and use shampoo
Prescription: (by weight percentage)
Lauryl alcohol sulphuric acid tri ethanol ammonium salt (40% aqueous solution) 40%
Polyoxyethylene (3) sodium lauryl ether sulphates (30 aqueous solution) 20%
Lauroyl diethanol ammonium 3% glycerol monopalmitate 1% lanoline 2%
Volatile spirits 10% propylene glycol 5% deionized water 17%
Essence, dyestuff, antiseptic, chelating agen surplus
Production method: above-mentioned former, adjuvant is prepared back heat fused in water-bath, stir, mix homogeneously, the back packing gets final product.
Using method: will bathe agent, bathe to join and bath in the bathtub about 30 minutes with shampoo, water temperature is 40~55 ℃, promote Transdermal absorption and Repiration by hot water and steam, so that the volatile spirits composition enter reach in the body regulate nervus centralis, loosen in meditation, unfold body and mind, thereby play the effect that promotes to fall asleep, improve sleep quality.
Embodiment 8: the foot-bath agent (oil) that promotes to fall asleep, improve sleep quality
Prescription: (by weight percentage)
Sodium lauryl sulfate 5% 95% ethanol 18% volatile spiritss 10%
Tween 80 2% deionized water 50%
Percutaneous absorption enhancer, antiseptic, dyestuff surplus
Production method: with the heated and stirred dissolving in water-bath of sodium lauryl sulfate, 95% ethanol, tween 80, Percutaneous absorption enhancer, antiseptic, dyestuff, deionized water, add volatile spirits after cooling again, stirring gets final product packaging product.
Using method: foot-bath agent (oil) is joined in the hot water, use its foot bath, because countless nerve endings closely link to each other with brain on the sole, the hot water foot bath promotes to absorb, can produce suppress cerebral cortex, make the people feel that brain is comfortable and loosen, can not only promote to fall asleep, and sleep is deepened, improve sleep quality.
Embodiment 9: promote to fall asleep, improve the production of sleep quality toothpaste
Prescription: (by weight percentage)
Glycerol 15% carboxymethyl cellulose 0.5% hydroxyethyl-cellulose 0.5%
Natural whiting 50% sodium lauryl sulfate 2% medicinal volatile spirits 5%
Essence 1% deionized water surplus
Production method: after earlier carboxymethyl cellulose, hydroxyethyl-cellulose being added the water heating for dissolving, add sodium lauryl sulfate, glycerol, natural whiting, essence successively and stir, treat that mastic evenly after, add volatile spirits again, stir, can pack after the cooling.
Embodiment 10: the chewing gum that promotes to fall asleep, improve sleep quality
Prescription: (by weight percentage)
Vinyl acetate 30% esterase 8% polyisobutylene 25%
Saccharum Sinensis Roxb. 18% acetyl group methyl ricinoleate 1%
Volatile spirits 5% calcium carbonate 12% Herba Menthae 1%
Production method: vinyl acetate, esterase, polyisobutylene, Saccharum Sinensis Roxb. are mixed; fully add hot milling; add acetyl group methyl ricinoleate, calcium carbonate then; again through mixing; in the mixture that obtains, add Herba Menthae and volatile spirits; again after fully mixing, send and roll that to prolong machine further mixing, the thickness section gets product in accordance with regulations then.
Toothpaste among using method: embodiment 9 and the embodiment 10, chewing gum is by brushing teeth or mastication, to stimulate the oral mucosa absorption pattern, directly permeate microcirculation, snap action in the cerebral nerve maincenter to play the effect that promotes to fall asleep, improve sleep quality.
Above said externally applied product all when maybe needing rest just before going to bed, use.

Claims (8)

1, a kind of volatile spirits that promotes to fall asleep, improve sleep quality is characterized in that: its quintessence oil by following raw material is by weight percentage formed Rhizoma Acori Graminei 60~90%; Rhizoma Zingiberis Recens 10~40%.
2, a kind of volatile spirits that promotes to fall asleep, improve sleep quality as claimed in claim 1, it is characterized in that: described Rhizoma Acori Graminei is 80~90%; Rhizoma Zingiberis Recens is 10~20%.
3, a kind of volatile spirits that promotes to fall asleep, improve sleep quality as claimed in claim 1 or 2 is characterized in that: also comprise the quintessence oil of Rhizoma et radix valerianae, the Rhizoma et radix valerianae consumption is 6~15% of described Rhizoma Acori Graminei and a Rhizoma Zingiberis Recens raw material gross weight.
4, a kind of volatile spirits that promotes to fall asleep, improve sleep quality as claimed in claim 3 is characterized in that: described Rhizoma et radix valerianae consumption is 10~15% of described Rhizoma Acori Graminei and a Rhizoma Zingiberis Recens raw material gross weight.
5, a kind of volatile spirits that promotes to fall asleep, improve sleep quality as claimed in claim 4, it is characterized in that: also comprise Semen Ziziphi Spinosae, Semen Platycladi, the Radix Aucklandiae, Cacumen Platycladi, five kinds of raw materials of Folium Perillae, the consumption of these five kinds of raw materials is respectively 3~8% of described Rhizoma Acori Graminei and Rhizoma Zingiberis Recens raw material gross weight.
6, a kind of volatile spirits that promotes to fall asleep, improve sleep quality as claimed in claim 5 is characterized in that: the consumption of described Semen Ziziphi Spinosae, Semen Platycladi, the Radix Aucklandiae, Cacumen Platycladi, five kinds of raw materials of Folium Perillae is respectively 6~8% of described Rhizoma Acori Graminei and Rhizoma Zingiberis Recens raw material gross weight.
7, a kind of externally applied product that promotes to fall asleep, improve the volatile spirits preparation of sleep quality as claimed in claim 1 is characterized in that: add excipient in the described volatile spirits and can be prepared into cream, frost, liniment, spray, perfume, floral water, air freshener, bath agent, bathe with shampoo, foot-bath agent (oil), toothpaste, chewing gum externally applied product.
8, a kind of promotion as claimed in claim 7 is sleeping, improve the externally applied product of the volatile spirits preparation of sleep quality, it is characterized in that: described excipient is a stearic acid, stearyl alcohol, monoglyceride, liquid paraffin, dehydrated alcohol, 95% ethanol, lanoline, vaseline, triethanolamine, propylene glycol, glycerol, sodium lauryl sulfate, cellulose gum, superfine Pelvetia siliquosa Tseng et C. F. Chang, lauryl alcohol sulphuric acid tri ethanol ammonium salt (40% aqueous solution), polyoxyethylene (3) sodium lauryl ether sulphates (30 aqueous solution), lauroyl diethanol ammonium, the glycerol monopalmitate, any or multiple in the tween 80.
CN 200410026278 2004-06-29 2004-06-29 Volatile extraction for promoting falling asleep and improving sleep quality and its product for external use Expired - Fee Related CN1268388C (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101152295B (en) * 2007-09-07 2011-05-11 上海南天体育休闲用品有限公司 Aromatic essential oil capable of exciting vitality and enjoying oneself, and uses of the same
CN101229247B (en) * 2007-12-28 2011-06-01 重庆理工大学 Medicine preparation for treating insomnia and preparing method thereof
CN101152296B (en) * 2007-09-07 2011-11-30 上海南天体育休闲用品有限公司 Aromatic essential oil capable of calming oneself and accelerating sleep, and uses of the same
CN103271854A (en) * 2013-05-23 2013-09-04 苏州谷力生物科技有限公司 Essential oil massage agent for promoting sleep and preparation method thereof
CN104117031A (en) * 2014-06-26 2014-10-29 张少维 Sleeping promoting essential oil
CN106974760A (en) * 2017-03-23 2017-07-25 周振坤 A kind of spontaneous heat pad blanket
CN107569665A (en) * 2017-09-13 2018-01-12 高康日化集团有限公司 A kind of shampoo for preventing and treating alopecia
CN116139070A (en) * 2022-12-23 2023-05-23 杭州健崃生物科技有限公司 Sleep-aiding cold compress gel and preparation method thereof

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101152295B (en) * 2007-09-07 2011-05-11 上海南天体育休闲用品有限公司 Aromatic essential oil capable of exciting vitality and enjoying oneself, and uses of the same
CN101152296B (en) * 2007-09-07 2011-11-30 上海南天体育休闲用品有限公司 Aromatic essential oil capable of calming oneself and accelerating sleep, and uses of the same
CN101229247B (en) * 2007-12-28 2011-06-01 重庆理工大学 Medicine preparation for treating insomnia and preparing method thereof
CN103271854A (en) * 2013-05-23 2013-09-04 苏州谷力生物科技有限公司 Essential oil massage agent for promoting sleep and preparation method thereof
CN103271854B (en) * 2013-05-23 2015-04-22 苏州谷力生物科技有限公司 Essential oil massage agent for promoting sleep and preparation method thereof
CN104117031A (en) * 2014-06-26 2014-10-29 张少维 Sleeping promoting essential oil
CN106974760A (en) * 2017-03-23 2017-07-25 周振坤 A kind of spontaneous heat pad blanket
CN107569665A (en) * 2017-09-13 2018-01-12 高康日化集团有限公司 A kind of shampoo for preventing and treating alopecia
CN107569665B (en) * 2017-09-13 2020-12-22 高康日化集团有限公司 Shampoo for preventing and treating alopecia
CN116139070A (en) * 2022-12-23 2023-05-23 杭州健崃生物科技有限公司 Sleep-aiding cold compress gel and preparation method thereof

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