CN1571767A - 托特罗定的制备方法 - Google Patents

托特罗定的制备方法 Download PDF

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Publication number
CN1571767A
CN1571767A CNA028171594A CN02817159A CN1571767A CN 1571767 A CN1571767 A CN 1571767A CN A028171594 A CNA028171594 A CN A028171594A CN 02817159 A CN02817159 A CN 02817159A CN 1571767 A CN1571767 A CN 1571767A
Authority
CN
China
Prior art keywords
general formula
methylphenyl
acid
methoxy
chloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA028171594A
Other languages
English (en)
Chinese (zh)
Inventor
Y·库马
M·普拉萨德
P·K·尼拉
S·密斯拉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Publication of CN1571767A publication Critical patent/CN1571767A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
CNA028171594A 2001-08-03 2002-08-02 托特罗定的制备方法 Pending CN1571767A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN829DE2001 IN191835B (enExample) 2001-08-03 2001-08-03
IN829/DEL/2001 2001-08-03

Publications (1)

Publication Number Publication Date
CN1571767A true CN1571767A (zh) 2005-01-26

Family

ID=11097097

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA028171594A Pending CN1571767A (zh) 2001-08-03 2002-08-02 托特罗定的制备方法

Country Status (10)

Country Link
US (1) US6822119B1 (enExample)
EP (1) EP1419135A4 (enExample)
CN (1) CN1571767A (enExample)
BR (1) BR0211691A (enExample)
CA (1) CA2456293A1 (enExample)
IN (1) IN191835B (enExample)
NO (1) NO20040482L (enExample)
PL (1) PL368600A1 (enExample)
WO (1) WO2003014060A1 (enExample)
ZA (1) ZA200400999B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104628552A (zh) * 2015-02-09 2015-05-20 许昌豪丰化学科技有限公司 一种新淬灭体系及其应用
CN114213265A (zh) * 2021-12-22 2022-03-22 南京美瑞制药有限公司 一种制备托特罗定氧化杂质的方法

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2517824A1 (en) * 2003-03-06 2004-09-16 Neela Praveen Kumar 3,3-diarylpropylamine derivatives and processes for isolation thereof
ES2235648B1 (es) * 2003-12-22 2006-11-01 Ragactives, S.L. Procedimiento para la obtencion de tolterodina.
EP1629834A1 (en) 2004-08-27 2006-03-01 KRKA, D.D., Novo Mesto Sustained release pharmaceutical composition of tolterodine
ITMI20041920A1 (it) * 2004-10-11 2005-01-11 Chemi Spa Processo per la preparazione di n, n-diisopropil-3-2-idrossi-5-metilfenil-3-fenil-propabammina
US7355077B2 (en) * 2004-10-28 2008-04-08 Dr. Reddy's Laboratories Limited Process for preparing tolterodine
JP4513535B2 (ja) * 2004-12-03 2010-07-28 住友化学株式会社 トルテロジンの製造方法
JP2007527923A (ja) * 2005-01-10 2007-10-04 テバ ファーマシューティカル インダストリーズ リミティド トルテロジンタルトレートの調製方法
ES2268987B1 (es) 2005-08-05 2008-02-01 Ragactives, S.L. Procedimiento para la obtencion de 3,3-difenilpropilaminas.
KR100647068B1 (ko) 2005-09-15 2006-11-23 하나제약 주식회사 라세믹ｎ,ｎ-디이소프로필-3-(2-히드록시-5-메틸페닐)-3-페닐프로판아민의 제조방법
KR100686351B1 (ko) * 2006-01-12 2007-02-22 주식회사 카이로제닉스 톨테로딘 라세미체의 제조방법
US7268257B1 (en) 2006-05-31 2007-09-11 Sumitomo Chemical Company, Limited Process for producing tolterodine
MXPA06007686A (es) * 2006-07-04 2008-01-07 Uquifa Mexico S A De C V Proceso para la obtencion del tartrato de tolterodina.
EP2175843B1 (en) 2007-08-08 2014-10-08 Inventia Healthcare Private Limited Extended release compositions comprising tolterodine
WO2010092500A2 (en) * 2009-02-12 2010-08-19 Alembic Limited A process for the preparation of tolterodine tartrate
US20120041235A1 (en) * 2009-02-17 2012-02-16 Pharmathen S.A. Process for the preparation of (r)-2-(3-diisopropylamino)-1-phenylpropyl)-4methylphenol and salts thereof
WO2012098044A1 (en) 2011-01-17 2012-07-26 Cambrex Profarmaco Milano S.R.L. Process for the preparation of n,n-diisopropyl-3-(2-hydroxy-5-methylphenyl)- 3-phenyl propylamine and its salts starting from a novel intermediate
EP2476665A1 (en) 2011-01-17 2012-07-18 Cambrex Profarmaco Milano S.r.l. Process for the preparation of N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)- 3-phenyl propylamine and its salts starting from a novel intermediate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5382600A (en) * 1988-01-22 1995-01-17 Pharmacia Aktiebolag 3,3-diphenylpropylamines and pharmaceutical compositions thereof
KR20000057548A (ko) * 1996-12-13 2000-09-25 알프레드 엘. 미첼슨 광학적 전송물질 및 결합재

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104628552A (zh) * 2015-02-09 2015-05-20 许昌豪丰化学科技有限公司 一种新淬灭体系及其应用
CN114213265A (zh) * 2021-12-22 2022-03-22 南京美瑞制药有限公司 一种制备托特罗定氧化杂质的方法

Also Published As

Publication number Publication date
EP1419135A1 (en) 2004-05-19
ZA200400999B (en) 2004-05-20
US20040249211A1 (en) 2004-12-09
WO2003014060A1 (en) 2003-02-20
IN191835B (enExample) 2004-01-10
BR0211691A (pt) 2004-11-09
CA2456293A1 (en) 2003-02-20
EP1419135A4 (en) 2006-01-11
US6822119B1 (en) 2004-11-23
PL368600A1 (en) 2005-04-04
NO20040482L (no) 2004-03-29

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication