CN1569216A - Nanometer natural biological protein bee product and its preparation - Google Patents
Nanometer natural biological protein bee product and its preparation Download PDFInfo
- Publication number
- CN1569216A CN1569216A CN 200410026072 CN200410026072A CN1569216A CN 1569216 A CN1569216 A CN 1569216A CN 200410026072 CN200410026072 CN 200410026072 CN 200410026072 A CN200410026072 A CN 200410026072A CN 1569216 A CN1569216 A CN 1569216A
- Authority
- CN
- China
- Prior art keywords
- natural biological
- type natural
- nano type
- bee
- honeybee
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention relates to a nanometer type natural biological protein bee products and manufacturing method thereof. It adopts the nanometer biological technology structure process, extracts and utilizes the pharmacody properties of the drug in the largest extent and optimize combines the supercritical extracted and purified biological active effective constituent. It has micro molecule effects for control releasing and targeting, and has duplex functions of healthy care and diet therapy for inhibiting the brain atrophy, high blood fat and diabetes. It provides a novel protection and treatment measures for lowering the blood sugar and blood fat, reversing the canceration. The invention comprises following constituents: propolis 5-50b, royal jelly 10-45b, bee pollen 15-40b, ganoderma lucidum 8-25b, gingko leaf 10-20b, aloe 8-25b, nervonic acid 4-15b, chitosan 4-10b, maple leaf 4-10b, honey suckle 10-15b, licorice 8-15b, hawthorn fruit 8-15b.(b is a weight unit)
Description
One, technical field:
The present invention relates to a kind of medicines and health protection, medicative diet for food therapy goods of forming with " integration of edible and medicinal herbs " bee product and animal and plant source elite, especially relate to a kind of Nano type natural biological albumen honeybee product and preparation method thereof.
Two, background technology:
In the civilization of the scientific and technological economic integration in the whole world, along with science and technology development with rapid changepl. never-ending changes and improvements, bee product is used among the difficult miscellaneous diseases such as diabetes, cardiovascular and cerebrovascular vessel, cancer more widely, be acknowledged as the medicament that has no side effect fully, but existing bee product is the bee glue product of more single composition, exist in various degree that the metal separation technology is relatively poor, content of beary metal is higher, be easy to generate allergy, biological activity protein is lower, product function can't satisfy the shortcoming of people's multiple demand.
Three, summary of the invention:
The present invention is in order to solve the weak point in the above-mentioned background technology, a kind of Nano type natural biological albumen honeybee product and preparation method thereof is provided, it adopts the nanometer biotechnology structural manufacturing process, extraction and application medicine pharmacological properties to greatest extent, optimize the biological activity active ingredient of compatibility " supercritical " purification by liquid extraction, micromolecule effect with controlled-release target, for suppressing brain atrophy, hyperlipidemia, diabetes, health care, medicative diet for food therapy dual-use function are arranged, provide new prophylactico-therapeutic measures for reducing sugar and fat, reverse canceration.
For achieving the above object, the technical solution used in the present invention is:
A kind of Nano type natural biological albumen honeybee product, its special character is to comprise following component: propolis 5-50b, Lac regis apis 10-45b, bee pollen 15-40b, Ganoderma 8-25b, Folium Ginkgo 10-20b, Aloe 8-25b, nervonic acid 4-15b, chitosan 4-10b, Folium Alangii 4-10b, Flos Lonicerae 10-15b, Radix Glycyrrhizae 8-15b, Fructus Crataegi 8-15b (wherein b is a unit of weight).
A kind of Nano type natural biological albumen honeybee product, its special character is to comprise following component: water-soluble bee glue 20-50b, purification Lac regis apis 20-45b, selected bee pollen 15-40b, nervonic acid 4-15b, Folium Alangii 4-10b, Flos Lonicerae 8-15b, Radix Glycyrrhizae 8-15b, Fructus Crataegi 8-15b, Flos Sophorae 5-15b (wherein b is a unit of weight).
A kind of Nano type natural biological albumen honeybee product, its special character is to comprise following component: Ganoderma 10-20b, the Aloe 10-15b of water-soluble bee glue 20-45b, purification Lac regis apis lyophilized powder 25-40b, selected bee pollen 30-40b, technology hydrolysis, chitosan 10-15b, Flos Sophorae 10-15b (wherein b is a unit of weight).
A kind of Nano type natural biological albumen honeybee product, its special character is to comprise following component: bee glue purifying 30-45b, Lac regis apis lyophilized powder 25-40b, bee pollen 20-35b, Folium Ginkgo 10-15b, chitosan 6-9b, Folium Alangii 5-8b, Flos Sophorae 10-25b (wherein b is a unit of weight).
Above-mentioned propolis is a water solublity, the royal jelly lyophilized powder of Lac regis apis for purifying, bee pollen is the elaboration that fresh water (FW) is removed the heavy metal foreign material, Ganoderma is the Ganoderma extract of wild natural drying, Aloe is the bright oven dry goods that extract, nervonic acid is an extract in the Acer Truncatum Buge kernel, and chitosan is meant marine organisms extraction active ingredient, and Folium Alangii is the young leaves of plucking early July in environment purification.
Also comprise ant unit, HY lecithin, cephalin, VE and synthetic protein thereof in the above-mentioned prescription.
A kind of manufacture method of Nano type natural biological albumen honeybee product, its special character is to comprise following operating procedure: with described each component respectively with-4 ℃ of-60 ℃ of fresh water (FW)s, cleaning and dipping, dissolving, purification, 180 minutes water treatment when with 50 ℃-90 ℃ of temperature fire being respectively again, the acid of assembly special process, pure hydrolysis separate invalid element, receive ethanol to doing, handle each component with biomembrane, eliminate antagonism, separate oxious component.
Above-mentioned steps comprises: each component is treated to refining raw material earlier, selected, dehydration, freezing, dry, grind, handle with the nanotechnology ultra micro, the change in polarity movement velocity is designed to 18-32 hundred million times/second, 4 ℃-65 ℃ of control temperature, time 150-3000 minute, capable again concentrating under reduced pressure high-speed jet atomization drying.
Above-mentioned end product is the slow controlled-release target capsule preparations of Nano type, pill, suppository, tablet, granule, medicated wine, sugared preparation, health promoting beverage preparation, medicative diet for food therapy goods.
Compared with prior art, the advantage and the effect that have of the present invention is as follows:
1, honeybee product and the synthetic protein of medicine for adopting nanotechnology ultrastructure technology, supercritical to purify in the main prescription of the present invention, monarch, minister, assistant in the prescription make medicine clear and definite, and dosage is accurate;
2, the present invention carries out traditional Chinese medical science pharmacology compatibility conditioning successively, removes the harmful Fructus Citri tangerinae resistance of medicine, utilizes counteract each other principle and special procure flavour of a drug 5 and use prescription of plant pharmacology, dialectical execute control, principle-method-recipe-medicines.Pay attention to biological activity and efficiently utilize, and the specific part of optimized choice plant is in the hope of optimum medicine efficacy, outstanding principal agent characteristic, rationally qualitative, quantitative.
3, the present invention is according to China's traditional Chinese medical science pharmacology innovative design novel composing prescription, aspect pharmacological effect, take into account science, novelty, feasibility and benefit, adopt modern nano biological new technique, new technology, new thing source, new device group to become brand-new modern high technology product.There are emergency, disease to have the exterior and the interior, people that old children's situation is arranged according to disease, different dosage, the property of medicine, drug effect have been designed, adopt unique slow controlled release nanometer filmogen on the technology of the package, thereby it is required to adapt to various patients, preparation had both kept the advantage of Chinese medicine soup clothes agent, had adopted the biological nano technology again, and volumes of formulation is dwindled, consumption reduces, drug effect improves, the patient is convenient, really belongs to the technological revolution of a Chinese medicine preparation.
4, the present invention plays immunization therapy and auxiliary treatment effect with reference to Chinese Pharmacopoeia treating both the principal and secondary aspects of a disease, scientific composition to brain atrophy, cardiovascular and cerebrovascular disease, malignant neoplastic disease, diabetes, endocrine disturbance, neurasthenia etc., is of value to slow down aging, nourishing the brain and improving intelligence.Provide a new treatment technology again to diabetes, cardiovascular and cerebrovascular disease, malignant neoplastic disease, hypertension, hepatitis etc.
Four, the specific embodiment:
Prescription of the present invention is:
Embodiment 1:
Get propolis 23 grams, Lac regis apis 20 grams, bee pollen 16 grams, Ganoderma 8 grams, Folium Ginkgo 6 grams, Aloe 5 grams, nervonic acid 3 grams, chitosan 2 grams, Folium Alangii 3 grams, Radix Glycyrrhizae 3 grams, Flos Lonicerae 7 grams, Fructus Crataegi 4 grams.
Embodiment 2:
Water intaking soluble bee glue 28 grams, purification Lac regis apis 22 grams, selected bee pollen 18 grams, Flos Lonicerae 17 grams, nervonic acid 3 grams, Folium Alangii 6 grams, Radix Glycyrrhizae 6 grams.
Embodiment 3:
Ganoderma 15 grams of water intaking soluble bee glue 26 grams, purification Lac regis apis lyophilized powder 23 grams, selected bee pollen 20 grams, technology hydrolysis, Aloe 10 grams, Flos Sophorae 6 grams.
Embodiment 4:
Get bee glue purifying 25 grams, Lac regis apis lyophilized powder 23 grams, bee pollen 15 grams, Flos Sophorae 13 grams, Folium Ginkgo 13 grams, chitosan 4 grams, Folium Alangii 7 grams.
Wherein propolis is a water solublity, the royal jelly lyophilized powder of Lac regis apis for purifying, bee pollen is the elaboration that fresh water (FW) is removed the heavy metal foreign material, Ganoderma is the Ganoderma extract of wild natural drying, Aloe is the bright oven dry goods that extract, nervonic acid is an extract in the Acer Truncatum Buge kernel, and chitosan is meant marine organisms extraction active ingredient, and Folium Alangii is the young leaves of plucking early July in environment purification.Also comprise ant unit, HY lecithin, cephalin, VE and synthetic protein thereof in the prescription.
Processing step comprises:
With above-mentioned each component respectively with-4 ℃ of-60 ℃ of fresh water (FW)s, cleaning and dipping, dissolving, purification, 180 minutes water treatment when with 50 ℃-90 ℃ of temperature fire being respectively again, the acid of assembly special process, pure hydrolysis, separate invalid element, receive ethanol, handle each component with biomembrane to doing, eliminate antagonism, separate oxious component.
Each component is treated to refining raw material as stated above, and its feature also comprises following 3 kinds of modes: 1. selected, dehydration, freezing, dry, grind.Handle with the nanotechnology ultra micro, the change in polarity movement velocity is designed to 18-32 hundred million times/second, 4 ℃-65 ℃ of control temperature, time 150-3000 minute, capable again concentrating under reduced pressure high-speed jet atomization drying.2. it is 30 minutes with the first cold water soak respectively of raw material of Chinese medicine, temperature rise control is 80 minutes for 20 ℃-35 ℃, 35 ℃-50 ℃ is the 180-300 branch, oxious component in the separation and Extraction medicine, oven dry is pulverized or freezing and pulverizing, place reaction to extract still Chinese medicine preparation and add process solvent, import microwave extracting, the change in polarity movement velocity is designed to 18-32 hundred million times/second, 26 ℃-65 ℃ of control temperature, 60 minutes-720 minutes time, utilize the micromolecule effect of nanostructured, impel that medical material active ingredient generation biological activity is outstanding to be changed.3. part medical material granule is worked into the ultra micro powdery of 80nm, carries out the herbal pharmacology extraction, carry out ultra micro emulsifying separation and Extraction for the medicine that contains kernel.Carry out concentrating under reduced pressure, ultrahigh speed jet spray drying again, 35 ℃-55 ℃ of temperature controls, 150 minutes-3600 minutes time.
The present invention includes the slow controlled-release target capsule preparations of Nano type, pill, suppository, tablet, granule, medicated wine, sugared preparation, health promoting beverage, medicative diet for food therapy goods.
The present invention finds that in research, experiment, analysis, prescription propolis is a kind of very precious rare natural resources, have the title of " purple gold ".Prove that through modern chemical analysis the elite of propolis massive planting thing has complexity and the unique chemical composition.Include 20 big classes kind of nutrition surplus in the of totally three hundred, wherein certified have more than 70 a kind of flavone compound, and it can regulate vascular function, bring high blood pressure down, improve blood circulation state, get final product building body, the treatment disease that can get rid of illness again is ideal health care, the treatment treasure of treatment modern social disease.
Lac regis apis is a kind of biological activity height and the strong natural tonic of pharmacological action, has the two-way function of health care pharmacology, and propolis and Lac regis apis compatibility have function stack potentiation.
Bee pollen is the pollen load that is processed into through Apis by the pollen that Apis is gathered from plant flowers, is described as " spissated natural Drug Storage ", " all-round nutrition library ".Pollen contains and impels the human organism to keep normal function and essential protein, aminoacid, vitamin, the enzyme of additional body, and contained abundant nucleic acid is the key component that participates in the life medium with albumen.
Ganoderan energy human body immunity improving power, hypoxia-bearing capability are eliminated the anti-radiation detoxifcation of free radical, and raising liver, bone marrow, blood flow DNA, rna protein ability have effects such as life-saving, antitumor.
Nervonic acid is a kind of long-chain monounsaturated fatty acid, has mainly existed in the human brain with glycosyl sphingolipid, sphingomyelins form, plays an important role in the biosynthesis of myelin.Nervonic acid is the important component part of neuron membrane, and neurotransmitter and health are played regulating action, by the adjusting of nervonic acid to the brain cell membrane function, can improve brain information and between brain cell, connect transmission, improve the calcium ion effect, stablize nervous system, improve the brain information system.
Claims (9)
1, a kind of Nano type natural biological albumen honeybee product is characterized in that comprising following component: propolis 5-50b, Lac regis apis 10-45b, bee pollen 15-40b, Ganoderma 8-25b, Folium Ginkgo 10-20b, Aloe 8-25b, nervonic acid 4-15b, chitosan 4-10b, Folium Alangii 4-10b, Flos Lonicerae 10-15b, Radix Glycyrrhizae 8-15b, Fructus Crataegi 8-15b (wherein b is a unit of weight).
2, a kind of Nano type natural biological albumen honeybee product is characterized in that comprising following component: water-soluble bee glue 20-50b, purification Lac regis apis 20-45b, selected bee pollen 15-40b, nervonic acid 4-15b, Folium Alangii 4-10b, Flos Lonicerae 8-15b, Radix Glycyrrhizae 8-15b, Fructus Crataegi 8-15b, Flos Sophorae 5-15b (wherein b is a unit of weight).
3, a kind of Nano type natural biological albumen honeybee product is characterized in that comprising following component: Ganoderma 10-20b, the Aloe 10-15b of water-soluble bee glue 20-45b, purification Lac regis apis lyophilized powder 25-40b, selected bee pollen 30-40b, technology hydrolysis, chitosan 10-15b, Flos Sophorae 10-15b (wherein b is a unit of weight).
4, a kind of Nano type natural biological albumen honeybee product is characterized in that comprising following component: bee glue purifying 30-45b, Lac regis apis lyophilized powder 25-40b, bee pollen 20-35b, Folium Ginkgo 10-15b, chitosan 6-9b, Folium Alangii 5-8b, Flos Sophorae 10-25b (wherein b is a unit of weight).
5, according to claim 1,2,3,4 described a kind of Nano type natural biological albumen honeybee products, it is characterized in that: propolis is a water solublity, the royal jelly lyophilized powder of Lac regis apis for purifying, bee pollen is the elaboration that fresh water (FW) is removed the heavy metal foreign material, Ganoderma is the Ganoderma extract of wild natural drying, and Aloe is the bright oven dry goods that extract, and nervonic acid is an extract in the Acer Truncatum Buge kernel, chitosan is meant marine organisms extraction active ingredient, and Folium Alangii is the young leaves of plucking early July in environment purification.
6, a kind of Nano type natural biological albumen honeybee product according to claim 5 is characterized in that: also comprise ant unit, HY lecithin, cephalin, VE and synthetic protein thereof in the prescription.
7, a kind of manufacture method of Nano type natural biological albumen honeybee product, it is characterized in that: with described each component respectively with-4 ℃ of-60 ℃ of fresh water (FW)s, cleaning and dipping, dissolving, purification, 180 minutes water treatment when with 50 ℃-90 ℃ of temperature fire being respectively again, the acid of assembly special process, pure hydrolysis separate invalid element, receive ethanol to doing, handle each component with biomembrane, eliminate antagonism, separate oxious component.
8, the manufacture method of a kind of Nano type natural biological albumen honeybee product according to claim 8, it is characterized in that comprising following operating procedure: each component is treated to refining raw material by above-mentioned steps, selected, dehydration, freezing, dry, grind, handle with the nanotechnology ultra micro, the change in polarity movement velocity is designed to 18-32 hundred million times/second, 4 ℃-65 ℃ of control temperature time 150-3000 minute, concentrate the high-speed jet atomization drying again.
9, the manufacture method of a kind of Nano type natural biological albumen honeybee product according to claim 8 is characterized in that: described end product is the slow controlled-release target capsule preparations of Nano type, pill, suppository, tablet, granule, medicated wine, sugared preparation, health promoting beverage preparation, medicative diet for food therapy goods.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410026072 CN1569216A (en) | 2004-04-27 | 2004-04-27 | Nanometer natural biological protein bee product and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410026072 CN1569216A (en) | 2004-04-27 | 2004-04-27 | Nanometer natural biological protein bee product and its preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1569216A true CN1569216A (en) | 2005-01-26 |
Family
ID=34480570
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410026072 Pending CN1569216A (en) | 2004-04-27 | 2004-04-27 | Nanometer natural biological protein bee product and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1569216A (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100381131C (en) * | 2006-06-07 | 2008-04-16 | 中国农业科学院蜜蜂研究所 | Bee pollen soft capsule and preparation method thereof |
| CN100381130C (en) * | 2006-06-07 | 2008-04-16 | 中国农业科学院蜜蜂研究所 | Bee pollen nutrition oral liquid and preparation method thereof |
| CN101564511B (en) * | 2009-05-05 | 2012-05-09 | 武兴战 | Natural protein product for treating diabetes and manufacture method |
| CN102613574A (en) * | 2012-03-29 | 2012-08-01 | 苏州圣隆营养食品有限公司 | Female nourishing health-care product |
| CN101445777B (en) * | 2008-12-29 | 2013-04-10 | 杭州蜂之语蜂业股份有限公司 | Production method of royal jelly protein wine |
| CN105851999A (en) * | 2016-06-24 | 2016-08-17 | 安徽省丰康农业科技有限公司 | Royal jelly oral preparation capable of improving internal secretion |
| CN108991453A (en) * | 2018-08-06 | 2018-12-14 | 重庆市畜牧科学院 | A kind of preparation method and products thereof of compound nano-propolis |
| CN109198543A (en) * | 2018-10-18 | 2019-01-15 | 湖北新阳蜂业有限公司 | A kind of queen bee paste composition |
-
2004
- 2004-04-27 CN CN 200410026072 patent/CN1569216A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100381131C (en) * | 2006-06-07 | 2008-04-16 | 中国农业科学院蜜蜂研究所 | Bee pollen soft capsule and preparation method thereof |
| CN100381130C (en) * | 2006-06-07 | 2008-04-16 | 中国农业科学院蜜蜂研究所 | Bee pollen nutrition oral liquid and preparation method thereof |
| CN101445777B (en) * | 2008-12-29 | 2013-04-10 | 杭州蜂之语蜂业股份有限公司 | Production method of royal jelly protein wine |
| CN101564511B (en) * | 2009-05-05 | 2012-05-09 | 武兴战 | Natural protein product for treating diabetes and manufacture method |
| CN102613574A (en) * | 2012-03-29 | 2012-08-01 | 苏州圣隆营养食品有限公司 | Female nourishing health-care product |
| CN105851999A (en) * | 2016-06-24 | 2016-08-17 | 安徽省丰康农业科技有限公司 | Royal jelly oral preparation capable of improving internal secretion |
| CN108991453A (en) * | 2018-08-06 | 2018-12-14 | 重庆市畜牧科学院 | A kind of preparation method and products thereof of compound nano-propolis |
| CN109198543A (en) * | 2018-10-18 | 2019-01-15 | 湖北新阳蜂业有限公司 | A kind of queen bee paste composition |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101292742B (en) | Health food for reinforcing immune function of human body and preparation technique thereof | |
| CN106668657A (en) | Beverage capable of lowering uric acid and lipid and preparation method of beverage | |
| Algethami et al. | Bee pollen: Clinical trials and patent applications | |
| CN107568736A (en) | Dealcoholic sobering-up medical science formula food | |
| Mindell | Dr. Earl Mindell's Herb Bible: Fight Depression and Anxiety, Improve Your Sex Life, Prevent Illness, and Heal Faster—the All-Natural Way | |
| CN101856384B (en) | Liver-protecting combination | |
| CN106214847A (en) | A kind of can the oral liquid and preparation method thereof of enhancing immunity | |
| CN101884783B (en) | Wheat bran polypeptide-containing anti-fatigue traditional Chinese medicine and preparation method thereof | |
| CN1569216A (en) | Nanometer natural biological protein bee product and its preparation | |
| CN104673614B (en) | Pearl wine and preparation method thereof | |
| CN102327541A (en) | Intensified snake-honeybee nano-selenium and germanium element capsule | |
| CN104522572A (en) | Radix puerariae powder capable of supplementing qi and benefit spleen | |
| CN101810337A (en) | Health food containing pseudo-ginseng and ganoderma lucidum and radix astragali | |
| CN101703533A (en) | Ginkgo ganoderma lucidum spore capsule and preparation method thereof | |
| CN102430110B (en) | CAlprostadil composite medicament of compound fermented cordyceps sinensis powder and alprostadil composite drug | |
| CN105994867A (en) | Chocolate with effect of improving immunity and preparation method thereof | |
| CN100379427C (en) | Tablet auxiliary product for increase of body immunological competence | |
| CN101088518A (en) | Medicine prepn for reducing blood sugar and regulating blood pressure | |
| CN104435072B (en) | A kind of extract and preparation method thereof with auxiliary hyperglycemic, reducing blood lipid | |
| CN106038743A (en) | Blood pressure reducing electuary, and preparation method and application thereof | |
| CN1294960C (en) | Anti-senescence bee medicine health care preparation | |
| CN106173128A (en) | A kind of chocolate with anti-fatigue effect and preparation method thereof | |
| CN102357151A (en) | Chinese medicinal composition for delaying senility and preparation process thereof | |
| CN101669995A (en) | Composite for treatment and health care of heart cerebrovascular diseases and preparation method thereof | |
| CN107467654B (en) | Kelp and sea cucumber compound extract and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Open date: 20050126 |