CN1565570A - Formulation for treating fetal leakage and fetal irritability and its preparing process - Google Patents

Formulation for treating fetal leakage and fetal irritability and its preparing process Download PDF

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CN1565570A
CN1565570A CN 03135363 CN03135363A CN1565570A CN 1565570 A CN1565570 A CN 1565570A CN 03135363 CN03135363 CN 03135363 CN 03135363 A CN03135363 A CN 03135363A CN 1565570 A CN1565570 A CN 1565570A
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radix
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root
fine powder
blood
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CN100350961C (en
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姚克敏
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Abstract

The invention relates to a formulation for treating fetal leakage and fetal irritability and its preparing process, wherein the formulation is prepared from Chinese medicinal herbs including prepared rhizome of rehmannia, Chinese angelica root, Ligusticum wallichii, radix paeoniae rubrathe, pilose asiabell root, astragalus root, poria cocos wolf, white atractylodes rhizome, dodder seed, eucommia bark, dipsacus root, herb of Chinese fevervine, donkey-hide gelatin, Chinese mugwort leafmulberry leaf, cuttle-bone, lotus seeds, baikal skullcap root, Bupleurum root, amomum fruit, licorice root, and jujube.

Description

Treatment vaginal bleeding during pregnancy, frequent fetal movement preparation and preparation method thereof
Technical field
The present invention relates to a kind of compound Chinese medicinal preparation that is used for the treatment of vaginal bleeding during pregnancy, frequent fetal movement, habitual abortion, diapause, and the preparation method of said preparation.
Background technology
Show that according to existing data the sickness rate of diseases such as " vaginal bleeding during pregnancy ", " frequent fetal movement ", " habitual abortion ", " diapause " is higher in recent years, reports such as Zhengzhou City's Jinshui District Han Xi of maternity and child care center phoenix, pregnant early stage hemorrhage rate accounts for 10.2%.Though China perinatal stage mother and baby mortality rate is than reducing year by year the pre-peaceful liberation period, but compare with advanced country in the world and to still have certain distance, how to improve the perinatal care level, multiply outstanding offspring, improve the health of the people, be still one of major issue that will solve in China's field of medicaments.To this, pools of traditional Chinese medicine has accumulated rich experience.In recent years, the clinical report of correlational study is also many, but mostly is the general clinical practice of Chinese medicine decoction, does not see system's report of aspects such as relevant Chinese medicine preparation and preparation technology.
Summary of the invention
The purpose of this invention is to provide the preparation that a kind of women of being used for gestation deficient qi and blood, sagging distention in the smaller abdomen, fatigue in both spirit and physical strength, soreness of waist lumbago, vaginal bleeding during pregnancy hematochezia, frequent fetal movement, diapause have good result.
Preparation of the present invention is the medicine pill of sending the proved recipe in seven generations handed down from one's ancestors to be made according to the white traditional Chinese medical science of Yao Zhen.Year surplus Yao Shi doctor family already cures 200 in Yunnan, passed on a skill of craft to others for seven generations, of long standing and well established, enjoy higher reputation socially, Yao Shi cures tame medical skill exquisiteness, is good at gynecological especially, the treatment vaginal bleeding during pregnancy that its accumulation sums up, frequent fetal movement proved recipe.
Preparation of the present invention is under traditional Chinese medicine theory instructs, the Chinese medicine preparation that forms on the proved recipe basis of summing up out in conjunction with the long-term clinical practice of Yao Shi doctor family, and its prescription is as follows:
Radix Rehmanniae Preparata 3~8 Radix Angelicae Sinensis 3~8 Rhizoma Chuanxiongs 1~4 Radix Paeoniae Alba 2~6 Radix Codonopsis 3~8
The Radix Astragali 3~8 Poria 2~6 Rhizoma Atractylodis Macrocephalaes 2~6 Semen Cuscutae 3~8 Cortexs Eucommiae 3~8
Radix Dipsaci 3~8 Caulis Polygoni Multiflori 2~6 Colla Corii Asini beads 3~8 Folium Artemisiae Argyis 2~6
Os Sepiae 2~6 Stamen Nelumbiniss 2~6 Radix Scutellariae (parched) 2~6 Radix Bupleuri 2~6 Folium Perillae 2~6
Fructus Amomi 2~6 Radix Glycyrrhizaes 1~3 fruit Qi 2~4 Fructus Jujubaes 2~4
Preparation technology: in 23 flavor medical materials of prescription, part is ground into the medical material fine powder; Part prepares extractum by the decocting method of Chinese medicine, and both admix evenly, and drying is ground into fine powder, is that bonding agent is made small honey pill or big honeyed pills with the refined honey, or is that binding agent is made water-honeyed pill with Mel and water.Be specially: clean 23 flavor medical materials of institute's compatibility by prescription, get Colla Corii Asini bead, the Fructus Amomi pulverize separately becomes fine powder, 21 flavors such as remaining Radix Rehmanniae Preparata, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Alba, decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, collecting decoction filters, and the filtrate heating is concentrated into extractum, with above-mentioned fine powder mixing, drying is ground into fine powder, sieve, add refined honey and make binding agent, make small honey pill or big honeyed pills or Mel water pill, promptly.
The theory of Chinese medical science basis and the characteristic of preparation of the present invention:
1, preparation of the present invention is to carry out prescription according to traditional Chinese medical theory and long-term clinical practice experience, and its prescription is rigorous.
Yao Shi doctor family is thought, the phase of gestation, QI and blood, liver spleen, most important towards appointing.Trimester of pregnancy, tire occupied female abdomen, and bad mother's gas carries the blood fetus nourishing, and gas is feotus vitality, and blood gathers fetus nourishing, and QI and blood is enriched can fetus nourishing carry tire; Spleen is a source of generating QI and blood, blood stored in the liver, and the strong fortune blood biochemistry of temper is active, and QI and blood is vigorous; Blood stored in the liver, the defeated cloth of the blood periphery of storage moistens the fetus nourishing youngster; CHONG meridian being the blood pool, REN meridian connecting with the uterus and pregnancy towards Ren Tongsheng, can make under the essence and blood among the defeated born of the same parents to educate tire, goes up flourish stomach through with flourish breast.So the cloudy essence of QI and blood is the material base that moistens the fetus nourishing youngster.If trimester of pregnancy is its female physical weakness, insufficiency of vital energy and blood, or work as overstrain, eating and drinking without temperance is worried depressed or because of the malignant histocytosis vomiting and nausea, injure taste, change source scarcity, menoxenia due to insufficiency of CHONG meridian, pregnant foster dereliction of duty is the carrying taking the photograph to carry and protect of flatus in the feotus vitality then, the irrigation of losing blood is moistened foster, then sends out to be cards such as vaginal bleeding during pregnancy, frequent fetal movement, diapause.
The big rule of prescription ancestor treatment should focus on the principal cause of a disease of the present invention is a monarch drug with eight delicacies with motherwort soup, the Radix Rehmanniae Preparata tonifying deficiency, promoting blood circulation, regulating menstruation are antiabortive, the pure sun of Radix Astragali nature, void that can tonifying five ZANG-organs, strongly invigorating primordial QI to be taking the photograph tire, for qi-invigorating herb; Radix Angelicae Sinensis, Rhizoma Chuanxiong benefiting blood and regulating blood circulation are controlled the blood vessels discord, and cloudy branch is not enough, and peaceful tire weighs down stillborn fetus, and the Rhizoma Atractylodis Macrocephalae is warm in nature not dry, kind strengthening the spleen and stomach, and specially the spleen reinforcing sun helps temper, and QI invigorating is carried tire, and the disease that the power of taking the photograph is controlled chong channel is received in enhancing, is the key medicine of back natural gift life; The Radix Codonopsis replenishing QI to invigorate the spleen helps the source of vital function to carry tire.The cooperation of all flavor medical materials can be played full, the healthy and vigorous effect of QI and blood of QI and blood.Blood is poly-can fetus nourishing, and gas fills to carry takes the photograph that to carry the power of protecting strong, then can be antiabortive, prevent miscarriage, control blood oozing from the body openings or subcuta neous tissue.With the effect of Semen Cuscutae, the Cortex Eucommiae, Radix Dipsaci, Caulis Polygoni Multiflori nourishing kidney the kidney invigorating, the kidney invigorating essence, Gu Chong appoints, and helps essence and blood, makes to dash to appoint astringency inducing, and the sea of blood is filled can consolidate tire, helps embryo, classifies ministerial drug as; Colla Corii Asini bead, Os Sepiae, Stamen Nelumbinis help solid feotus vitality by nourishing YIN and benefiting blood, hemostatic effect, so be listed as ministerial drug.After women's gestation, blood gathers fetus nourishing, the liver-fire movability, or have hot and suffocating or experience exterior-heat so be equipped with golden deficient Radix Scutellariae Tonga Radix Bupleuri, Radix Scutellariae is an adjuvant drug; Medical material in the prescription is transferred to dash and is appointed filling blood, and the gas medicine that reinforces the kidney is many, and after the gestation, the qi of chong channel ascending adversely superinverse, so should be equipped with Fructus Amomi, Folium Perillae with regulating stomach-QI, this two flavors medicine also has antiabortive effect to help its event of preventing miscarriage also to be listed as adjuvant drug simultaneously; Fructus Jujubae, the fruit Qi can blood-supplementing blood-nourishing, again can priming in the spleen kidney, blood system, so and Radix Glycyrrhizae be messenger drug altogether.
In sum, all medicine compatibilities gather benefiting QI and nourishing blood altogether, Gu towards antiabortive effect, be used for women's gestation deficient qi and blood, sagging distention in the smaller abdomen, fatigue in both spirit and physical strength, soreness of waist pain, vaginal bleeding during pregnancy hematochezia, frequent fetal movement, the diapause is as good effect.
2, safety and clinical efficacy statistics
(1) through the clinical practice of many cases, do not find toxic and side effects.
(2) acute toxicity test in mice
The result shows that preparation toxicity of the present invention is minimum, can not survey LD 50, maximum tolerance determination is 504g crude drug/kg, quite 680 times of the human clinical dosage.
(3) clinical efficacy statistics
Through and Western medicine group paired observation statistics, honeyed pill group 36 examples, total effective rate 97.9%, Western medicine group 36 examples (progesterone injection 20m, intramuscular injection every day once, continuous 7 days; Salbutamol sheet 2.4mg, every day is oral twice, vitamin E capsule 100mg obeys 1 time every day, continuous 7 days) total effective rate 78.5%.
Clinical observation result is as follows:
One, diagnostic criteria: " traditional Chinese medical science disease diagnosis criterion of therapeutical effect " according to institution of higher learning's teaching material middle threatened abortion of version " obstetrics and gynecology ", habitual abortion diagnostic criteria and nineteen ninety-five State Administration of Traditional Chinese Medicine's issue in 1998 formulated.
Two, clinical symptoms: vaginal bleeding during pregnancy, before pregnant 28 weeks, vagina is hemorrhage on a small quantity, the person of ending in the time of at present; Frequent fetal movement, before pregnant 28 weeks, the soreness of waist, abdominal part expands to weigh down and has a pain, or with a small amount of bleeder.
The diapause: gestation has vaginal bleeding during pregnancy, frequent fetal movement or does not have obvious clinical symptoms, but fetal development is slow, less than the pregnant time person.
Three, lab testing: the clear human chorionic gonadotropin of hematuria, (positive of β-HCG), ultrasound diagnosis be pregnant capsule or plumule or fetal rhythm person.
Four, include case in: all vaginal bleeding during pregnancys that meets, frequent fetal movement diagnostic criteria person, and can take by doctor's advice and be subjected to reagent person, include the selection case in, carry out the clinical observation curative effect contrast test.
Five, MAIN OUTCOME MEASURES:
Clinical symptoms: menolipsis time, bleeding time, waist and belly situation.
Lab testing: hematochrome, progesterone, urine HCG
Ultrasound diagnosis: pregnant capsule, plumule, fetal rhythm, pregnant week.
Six, observational technique
Single at random blind method is tested preparation group 36 examples of the present invention, Western medicine group 36 examples.
Seven, method of administration: preparation group of the present invention: 9g of small honey pill.One time 1 ball of big honeyed pills, 3 times on the one, 10 days is a course of treatment.
Western medicine group: by drafting the clinical treatment administration, 7 days courses of treatment.
Eight, observed result: (seeing the following form)
Table two group administration curative effect contrast observing statistics
Total routine number The example number Cure Take a turn for the better Invalid Total effective rate (%)
Preparation of the present invention ????36 Vaginal bleeding during pregnancy 23 frequent fetal movement 13 ????19 ????12 ????3 ????1 ????1 ????0 ????95.7 ????100
Western medicine group ????36 Vaginal bleeding during pregnancy 25 blastokinesis uneasinesses 11 ????16 ????7 ????3 ????2 ????6 ????2 ????76 ????81.8
Preparation total effective rate of the present invention and Western medicine group be P<0.05 relatively
The result shows, preparation for treating vaginal bleeding during pregnancy of the present invention, and the curative effect of frequent fetal movement obviously is better than the Western medicine group.
Above first phase clinical case observed result organizes expert testimony to pass through through the Kunming State Scientific and Technological Commission, and obtains 2002 annual Kunming scientific and technological progress third prizes.
The specific embodiment:
Embodiment 1:
Selected following medical material (kilogram):
Radix Rehmanniae Preparata 3 Radix Angelicae Sinensis 3 Rhizoma Chuanxiongs 1 Radix Paeoniae Alba 2 Radix Codonopsis 3 Radixs Astragali 3 Poria 2 Rhizoma Atractylodis Macrocephalaes 2
Semen Cuscutae 3 Cortexs Eucommiae 3 Radix Dipsacis 3 Caulis Polygoni Multiflori 2 Colla Corii Asini beads 3 Folium Artemisiae Argyis 2 Os Sepiae 2
Stamen Nelumbinis 2 Radix Scutellariae (parched) 2 Radix Bupleuri 2 Folium Perillae 2 Fructus Amomis 2 Radix Glycyrrhizaes 1 fruit Qi 2 Fructus Jujubaes 2
To prepare by the following method after the clean processing of above-mentioned medical material:
(1) preparation of Colla Corii Asini bead: earlier Pulvis concha Mactrae is put a pot internal heating, put into the dice shape fritter Colla Corii Asini that cuts to easily the time, fry to heaving into the garden pearl, be yellow-white, take out immediately, sieve removes Pulvis concha Mactrae, cools, is ground into fine powder, crosses 100 mesh sieves, and is standby; The powder recovery rate is about 98%.
(2) amomum powder is broken into fine powder and crosses 100 mesh sieves, standby fine powder recovery rate is about 95%.
(3) the residue medical material adds 10 times of water gagings and decocts, and 2 hours for the first time, 1.5 hours for the second time, twice decoction liquor merged, and filters, and it is 1.3 (80 ℃) clear paste (recovery rate is 25%-30%) that heating is condensed into relative density.
(4) with stirring in (1), (2), two kinds of fine powders adding clear paste, place drip pan carrying out drying below 80 ℃, be ground into fine powder and cross 80 mesh sieves, standby.
(5), with (4) gained fine powder, add that refined honey 50-70g makes small honey pill or big honeyed pills or with the Mel water pill, promptly by 100g.
Embodiment 2:
Selected following medical material (kilogram):
Radix Rehmanniae Preparata 5 Radix Angelicae Sinensis 5 Rhizoma Chuanxiongs 2 Radix Paeoniae Alba 4 Radix Codonopsis 5 Radixs Astragali 5 Poria 4 Rhizoma Atractylodis Macrocephalaes 4
Semen Cuscutae 5 Cortexs Eucommiae 5 Radix Dipsacis 5 Caulis Polygoni Multiflori 4 Colla Corii Asini beads 5 Folium Artemisiae Argyis 4 Os Sepiae 4
Stamen Nelumbinis 4 Radix Scutellariae (parched) 4 Radix Bupleuri 4 Folium Perillae 4 Fructus Amomis 4 Radix Glycyrrhizaes 2 fruit Qis 4 Fructus Jujubaes 4
To prepare by the following method after the clean processing of above-mentioned medical material:
Get Colla Corii Asini bead, the Fructus Amomi pulverize separately becomes fine powder to cross 100 mesh sieves, and is standby; 21 flavor medical materials such as remaining Radix Rehmanniae Preparata, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Alba are used with embodiment 1 same procedure and are obtained decoction liquor, merge filtrate twice, filter, heating is concentrated into the extractum of 12 Bo Meidu, enters spray dryer, carries out spray drying, the fine powder that obtains is crossed 100 mesh sieves, merge two kinds of fine powders, cross 80 mesh sieve mixings, every 100g powder adds refined honey 50-70g and makes small honey pill, big honeyed pills promptly.
Embodiment 3:
Selected following medical material (kilogram):
Radix Rehmanniae Preparata 8 Radix Angelicae Sinensis 8 Rhizoma Chuanxiongs 4 Radix Paeoniae Alba 6 Radix Codonopsis 6 Radixs Astragali 8 Poria 6 Rhizoma Atractylodis Macrocephalaes 6
Semen Cuscutae 6 Cortexs Eucommiae 8 Radix Dipsacis 8 Caulis Polygoni Multiflori 6 Colla Corii Asini beads 8 Folium Artemisiae Argyis 6 Os Sepiae 6
Stamen Nelumbinis 6 Radix Scutellariae (parched) 6 Radix Bupleuri 6 Folium Perillae 6 Fructus Amomis 6 Radix Glycyrrhizaes 3 fruit Qis 6 Fructus Jujubaes 6
The clean method of pressing embodiment 1 or embodiment 2 in the back of handling of above-mentioned medical material is prepared.
The gained finished product is tested by the quality standard requirement of this preparation, and product quality inspection is qualified, can be used for clinical.

Claims (5)

1, a kind of preparation for the treatment of vaginal bleeding during pregnancy, frequent fetal movement is characterized in that it being the preparation of being made by the medicine material of following weight proportion:
Radix Rehmanniae Preparata 3~8 Radix Angelicae Sinensis 3~8 Rhizoma Chuanxiongs 1~4 Radix Paeoniae Alba 2~6 Radix Codonopsis 3~8
The Radix Astragali 3~8 Poria 2~6 Rhizoma Atractylodis Macrocephalaes 2~6 Semen Cuscutae 2~6 Cortexs Eucommiae 3~8
Radix Dipsaci 3~8 Caulis Polygoni Multiflori 2~6 Colla Corii Asini beads 3~8 Folium Artemisiae Argyis 2~6
Os Sepiae 2~6 Stamen Nelumbiniss 2~6 Radix Scutellariae (parched) 2~6 Radix Bupleuri 2~6 Folium Perillae 2~6
Fructus Amomi 2~6 Radix Glycyrrhizaes 1~3 fruit Qi 2~4 Fructus Jujubaes 2~4
2, according to the preparation of the described treatment vaginal bleeding during pregnancy of claim 1, frequent fetal movement, wherein the weight proportion of each medicine material is:
Radix Rehmanniae Preparata 5 Radix Angelicae Sinensis 5 Rhizoma Chuanxiongs 2 Radix Paeoniae Alba 4 Radix Codonopsis 5 Radixs Astragali 5 Poria 4 Rhizoma Atractylodis Macrocephalaes 4
Semen Cuscutae 4 Cortexs Eucommiae 5 Radix Dipsacis 5 Caulis Polygoni Multiflori 4 Colla Corii Asini beads 5 Folium Artemisiae Argyis 4 Os Sepiae 4
Stamen Nelumbinis 4 Radix Scutellariae (parched) 4 Radix Bupleuri 4 Folium Perillae 4 Fructus Amomis 4 Radix Glycyrrhizaes 2 fruit Qis 4 Fructus Jujubaes 4
3,, it is characterized in that described preparation is the above a dosage form of any pharmaceutics according to the preparation of claim 1,2 described treatment vaginal bleeding during pregnancys, frequent fetal movement.
4,, it is characterized in that described preparation is small honey pill or big honeyed pills or Mel water pill according to the preparation of the described treatment vaginal bleeding during pregnancy of claim 3, frequent fetal movement.
5,, it is characterized in that carrying out according to the following steps according to the preparation method of the described preparation of claim 1:
(1) preparation of Colla Corii Asini bead: earlier Pulvis concha Mactrae is put a pot internal heating, put into the dice shape fritter Colla Corii Asini that cuts to easily the time, fry to heaving into the garden pearl, be yellow-white, take out immediately, sieve removes Pulvis concha Mactrae, cools, is ground into fine powder, crosses 100 mesh sieves, and is standby;
(2) amomum powder is broken into fine powder and crosses 100 mesh sieves, standby;
(3) the residue medical material adds 10 times of water gagings and decocts, and 2 hours for the first time, 1~2 hour for the second time, twice decoction liquor merged, and filters, and it is 1.3 (80 ℃) extractum that heating is condensed into relative density;
(4) with stirring in (1), (2), two kinds of fine powders adding extractum, place drip pan carrying out drying below 80 ℃, be ground into fine powder and cross 80 mesh sieves, standby;
(5), add refined honey 50-70g by 100g and make small honey pill or big honeyed pills or Mel water pill, promptly with (4) gained fine powder.
CNB031353630A 2003-07-05 2003-07-05 Formulation for treating fetal leakage and fetal irritability and its preparing process Expired - Fee Related CN100350961C (en)

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CN102600388A (en) * 2012-03-29 2012-07-25 常熟市海虞茶叶有限公司 Traditional Chinese herbal medicine for treating threatened abortion of livestock
CN102641467A (en) * 2012-03-30 2012-08-22 王伟 Abortion-prevention traditional Chinese medicine composition
CN102652767A (en) * 2011-03-02 2012-09-05 华中科技大学 Drug for promoting embryo implantation and preparation method thereof
CN102805854A (en) * 2012-08-20 2012-12-05 冯晓华 Traditional Chinese medicine composition for treating pregnancy reaction
CN103751747A (en) * 2014-01-16 2014-04-30 曲洪翠 Traditional Chinese medicine for treating vaginal bleeding after medical abortion
CN104043064A (en) * 2013-03-12 2014-09-17 范德润 Traditional Chinese medicine preparation for treating uterine functional bleeding
CN104189642A (en) * 2014-09-05 2014-12-10 扬中牧乐药业有限公司 Traditional Chinese medicine preparation for preventing abortion of sow
CN104367652A (en) * 2014-10-13 2015-02-25 深圳市前海安测信息技术有限公司 Traditional Chinese medicine composition for treating sub-health and preparation method thereof
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CN105748997A (en) * 2016-03-31 2016-07-13 邱发龙 Pharmaceutical composition for treating early threatened abortion with subchorionic hematoma
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CN106620044A (en) * 2016-12-07 2017-05-10 吉林省畜牧兽医科学研究院 Traditional Chinese medicine composition for preventing miscarriage of pregnant sows and preparation method thereof
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CN102652767A (en) * 2011-03-02 2012-09-05 华中科技大学 Drug for promoting embryo implantation and preparation method thereof
CN102600388A (en) * 2012-03-29 2012-07-25 常熟市海虞茶叶有限公司 Traditional Chinese herbal medicine for treating threatened abortion of livestock
CN102600388B (en) * 2012-03-29 2013-12-04 太仓市临江农场专业合作社 Traditional Chinese herbal medicine for treating threatened abortion of livestock
CN102641467A (en) * 2012-03-30 2012-08-22 王伟 Abortion-prevention traditional Chinese medicine composition
CN102805854A (en) * 2012-08-20 2012-12-05 冯晓华 Traditional Chinese medicine composition for treating pregnancy reaction
CN104043064A (en) * 2013-03-12 2014-09-17 范德润 Traditional Chinese medicine preparation for treating uterine functional bleeding
CN103751747A (en) * 2014-01-16 2014-04-30 曲洪翠 Traditional Chinese medicine for treating vaginal bleeding after medical abortion
CN104189642A (en) * 2014-09-05 2014-12-10 扬中牧乐药业有限公司 Traditional Chinese medicine preparation for preventing abortion of sow
CN104367652A (en) * 2014-10-13 2015-02-25 深圳市前海安测信息技术有限公司 Traditional Chinese medicine composition for treating sub-health and preparation method thereof
CN105412799A (en) * 2015-12-27 2016-03-23 鹿哲维 Traditional Chinese medicine composition for treating blood-heat type atrophied fetus
CN105748997A (en) * 2016-03-31 2016-07-13 邱发龙 Pharmaceutical composition for treating early threatened abortion with subchorionic hematoma
CN106421234A (en) * 2016-10-14 2017-02-22 单县领翔金银花种植合作社 Traditional Chinese medicine for treating spleen and kidney deficiency type threatened abortion
CN106620044A (en) * 2016-12-07 2017-05-10 吉林省畜牧兽医科学研究院 Traditional Chinese medicine composition for preventing miscarriage of pregnant sows and preparation method thereof
CN106620044B (en) * 2016-12-07 2020-01-07 吉林省畜牧兽医科学研究院 Traditional Chinese medicine composition for preventing miscarriage of pregnant sows and preparation method thereof
CN106692858A (en) * 2016-12-29 2017-05-24 王勤 Medicine for treating threatened abortion and preparation method of medicine

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