CN1562319A - Medication for curing skin disease - Google Patents

Abstract

A Chinese medicine for treating dermatopathy, such as acne, seborrheic dermatitis, eczema, foll iculitis, etc is prepared from 8 Chinese-medicinal materials including honeysuckle flower, forsythia fruit, forsythia fruit, chrysanthemum flower, scutellaria root, etc.

Description

The dermopathic medicine of a kind of treatment

One, technical field

The present invention relates to the dermopathic medicine of a kind of treatment, specifically is the Chinese patent medicine of feedstock production with the Chinese herbal medicine.

Two, background technology

Dermatosiss such as acne, seborrheic dermatitis, folliculitis, eczema, impetigo, furuncle carbuncle, erysipelas are dermatology common disease, frequently-occurring disease, treat rather thorny.The present medicine that uses mostly takes effect slowly, the course of treatment is long, can not remove old complaint, easily recurrence, and the part medicine also has certain toxic and side effects, and not retrieving in the prior art has good therapeutic effect to above-mentioned dermatosis, and the Chinese medicine that has no side effect.

Three, summary of the invention

The object of the present invention is to provide a kind of medicine that above-mentioned dermatosis is had good therapeutic effect and has no side effect.

For achieving the above object, it is that feedstock production becomes a kind of Chinese patent medicine that the present invention adopts multiple Chinese herbal medicine.It is made up of the component of following parts by weight:

Flos Lonicerae 700-800 Fructus Forsythiae 400-500 Flos Chrysanthemi 300-400

Radix Scutellariae 300-400 Cortex Phellodendri 400-550 Radix Et Rhizoma Rhei 200-300

It clothing powder 300-400 Radix Paeoniae Rubra 300-450.

The optimization formula of preparation medicine of the present invention is:

Flos Lonicerae 740-800 Fructus Forsythiae 400-460 Flos Chrysanthemi 350-400

Radix Scutellariae 300-350 Cortex Phellodendri 420-520 Radix Et Rhizoma Rhei 230-280

It clothing powder 320-380 Radix Paeoniae Rubra 350-450.

Chinese medicine preparation of the present invention can be said dosage form on any pharmaceutics, as: granule, tablet, capsule, oral liquid, pill, syrup agent, buccal tablet, effervescent tablet, dispersible tablet.

This prescription is the principle according to tcm treatment according to syndrome differentiation at first, adopting classical prescription in ancient times " wuwei xiaodu drink ", " Rhizoma Coptidis toxic materials clearing away decoction ", " Xian fang Huoming Yin " to change the sanction plus-minus forms, increase along with time and patient's case load, curative effect is affirmed, the each side reflection is good, progressively forms this side's blank, tries out in clinical, augment through repeatedly cutting out to delete, form prescription of today.It is to treating above-mentioned disease determined curative effect.It is in close relations with lung, kidney, the heart, spleen, large intestine channel that particularly acne, seborrheic dermatitis, (face) folliculitis, (face) eczema, theory of Chinese medical science are thought more, how by the lung meridian heat in blood, and the diseases caused by exogenous pathogenic factor ailment said due to cold or exposure, heart channel latent heat is loved and is not gone.Pathogenic heat are violated skin outward, and upward smoked women's head-ornaments and play rash, or surfeit delicious food savoury, taste are received dysfunction of the spleen in transportation and transformation, give birth in damp and hot, accumulate heat-transformation of a specified duration, and are strongly fragrant in blood system, overflow in skin.Or dysfunction of the spleen in transportation, retention of water-damp in the body, the strongly fragrant expectorant that stagnates into for a long time, inside and outside two heresies are rich mutually, fill in space between skin and muscles, send out and cause a disease in skin, so, meet above-mentioned disease clinically, according to the tcm treatment according to syndrome differentiation theory, meet wind heat attack skin, heat in blood lose support, excessive noxious heat, retention of damp-heat in the interior person all can use the present invention.

First-selected Flos Lonicerae is monarch in the side.

The Flos Lonicerae nature and flavor are sweet, go into lung, stomach, large intestine, heart channel, heat-clearing and toxic substances removing, and the hot fragrance of this product is dense, the heat of kind clearing heat in QI system branch, and the diffusing merit of a surname is arranged, among the heat clearing away again again because of its heat-clearing and toxic substances removing power is strong, for sore swollen toxin, the tool red and swollen heat pain belongs to YANG syndrome person, all can select for use, also is surgery medicine commonly used.

With Fructus Forsythiae, Flos Chrysanthemi is ministerial drug.

The bitter little suffering of Fructus Forsythiae nature and flavor, be slightly cold, go into the lung heart, gallbladder meridian, its light weight is floating, has the effect of heat-clearing and toxic substances removing, detumescence and apocenosis, eliminating carbuncle eliminating stagnation, can treat various sore swollen toxins.

The Flos Chrysanthemi nature and flavor are sweet, hot, bitter cool, go into lung, Liver Channel, dispelling wind, heat clearing away, suppressing the hyperactive liver and make eye bright, detoxify, can treat furuncle, toxic swelling, clinical many Herba Tagetis Patulae of use are because of this medicine " its bitter in the mouth of yellow person is heavy, and faint scent is diffusing, main lung heat clearing fire "---" medicine justice ".The power of its dispelling wind and heat pathogens, the detoxifcation of relieving inflammation or internal heat is higher, is used for the disease of wind-heat invading the lung more.

Fructus Forsythiae, Flos Chrysanthemi two medicines cooperate, and have the effect of dredging heat, detoxifcation, evacuation of pus, the heat of auxiliary monarch drug lung heat clearing, gastric qi branch.

Radix Scutellariae, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Trichosanthis, Radix Paeoniae Rubra five medicines are adjuvant drug altogether.

Radix Scutellariae nature and flavor hardship, cold is gone into the heart, lung, gallbladder, large intestine channel, heat clearing and damp drying, eliminating fire and detoxication.Ancient Chinese medicine doctor thinks that all the light property of this medicine ducted body is floating, goes into meridian of Hand-TAI YIN, and merit is partial to clear purte the white, and the heat of expelling pathogenic factors from muscles table is gone into meridian of Hand-TAI YANG, then rushes down the fire of the large intestine part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels.

Cortex Phellodendri nature and flavor hardship, cold is gone into kidney, bladder, large intestine channel, and pathogenic fire purging, dampness, detoxifcation are given birth to the time spent and fallen excess-fire, and the merit of heat clearing and damp drying is more outstanding, is usually used in treating because of the illness such as carbuncle skin infection due to the excessive noxious heat.

Radix Et Rhizoma Rhei nature and flavor hardship, cold is gone into stomach, large intestine, Liver Channel.The poison that purges heat swings stagnantly, and clots absorbing blood is controlled carbuncle skin ulcer furuncle, and Radix Et Rhizoma Rhei is given birth to usefulness, and the stasis removing gesture is violent, and eliminating fire and detoxication power is strong.

Sweet, the little hardship of Radix Trichosanthis nature and flavor, acid, be slightly cold, go into lung, stomach warp, clearing away heat and promoting production of body fluid, pathogenic fire reducing and moisturize evacuation of pus detumescence, but smelting carbuncle, acute mastitis.

Radix Paeoniae Rubra nature and flavor hardship, acid, be slightly cold, go into lung, spleen channel, clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain can be used for cards such as sore and toxic.

Five medicines close the assistant monarch drug, heat-clearing and toxic substances removing, the heat of leading the lung stomach off, Radix Scutellariae, Cortex Phellodendri, Radix Et Rhizoma Rhei swing the heat of three warmers, clots absorbing blood, swing stagnant, the Radix Trichosanthis clearing away heat and promoting production of body fluid, pathogenic fire reducing is moisturized, evacuation of pus detumescence, the purify the blood heat of branch of Radix Paeoniae Rubra, the tool removing heat from blood, invigorate blood circulation, the merit of blood stasis dispelling.

Chinese crude drug of the present invention is Chinese Pharmacopoeia and collects kind.

This preparation was once done clinical trial in early stage, during 2000-2002, collecting example surplus the clinic case 1300, comprise and be used for acne (476 example), seborrheic dermatitis (139 example), eczema (328 example), folliculitis (64 example), impetigo (38 example), furuncle carbuncle (125 example), erysipelas (20 example), total effective rate reaches 86.3%, does not see obvious adverse reaction or toxic reaction during the treatment.Wherein the male patient accounts for 54.2%, female patient accounts for 45.8%, age 12-67 year, the course of disease 5 days-12 years, its common symptoms is that pimple, erythema, pus point, pustule, redness, protuberance, incrustation, desquamation, tenderness, scratch, incrustation, color mostly are scarlet or kermesinus substantially, light red tongue or dark red, yellow and thin fur or few tongue, floating and rapid pulse or stringy and rapid pulse.

Curative effect determinate standard:

Cure: the clinical symptom disappearance more than 90%.

Produce effects: clinical symptoms is obviously improved or is alleviated.(＞60％)

Take a turn for the better: clinical symptoms, Signs make moderate progress or alleviate (＞30%)

Invalid: clinical symptoms, the basic no change of Signs (＜10%)

Recurrence: the treatment back occurred and original identical skin lesion at former position after March.

Effective percentage: for curing the summation that produce effects takes a turn for the better.

Medication is carried out efficacy evaluation after 2 weeks, and the case after the healing schedules to last following up a case by regular visits to of half a year, and the result is as follows:

Acne: the pimple decreased number, new dermexanthesis quantity is less than the rash quantity that disappears, and pustule disappears, tuberosity dwindles or disappear effective percentage 89.2%, relapse rate 13.2%.

Seborrheic dermatitis: the erythema color is changeed light, squama minimizing, and the skin lesion scope is dwindled, effective percentage 82.6%, relapse rate 10.7%.

Folliculitis: the inflammatory pimple disappears, tenderness transference cure or alleviate effective percentage 88.5%, relapse rate 5.2%.

Eczema: erythema pimple major part disappears, and it is light that color is changeed, and subjective symptoms alleviates or eliminates, effective percentage 74.8%, relapse rate 15.7%.

Impetigo: elimination is oozed out in erosion, and the skin lesion incrustation is dry, new dermexanthesis do not occur, effective percentage 83.3%, relapse rate 0%.

The furuncle carbuncle: red and swollen bump pad disappears or major part alleviates, and red, swollen, hot, pain phenomenon eliminates or part is eliminated effective percentage 72.7%, relapse rate 2.1%.

Erysipelas: skin lesion surface redness disappears, and pain is eliminated, and the regional glandular enlargement phenomenon disappears, effective percentage 94%, relapse rate 0%.

In sum, we think that the present invention fills a prescription to form certain reasonability is arranged, effectiveness, safety, and raw material is easy to get, and cost is relatively low, after carrying out industrialization and producing, will produce obvious social and economic benefit.

Four, the specific embodiment

Embodiment 1, take by weighing raw material by following prescription and be prepared (kilogram):

Flos Lonicerae 710 Fructus Forsythiaes 480 Flos Chrysanthemis 300

Radix Scutellariae 380 Cortex Phellodendris 550 Radix Et Rhizoma Rhei 270

They clothing powder 350 Radix Paeoniae Rubra 300.

Embodiment 2, take by weighing raw material by following prescription and be prepared (kilogram):

Flos Lonicerae 750 Fructus Forsythiaes 430 Flos Chrysanthemis 370

Radix Scutellariae 330 Cortex Phellodendris 470 Radix Et Rhizoma Rhei 260

They clothing powder 380 Radix Paeoniae Rubra 400.

Embodiment 3, take by weighing raw material by following prescription and be prepared (kilogram):

Flos Lonicerae 790 Fructus Forsythiaes 400 Flos Chrysanthemis 340

Radix Scutellariae 300 Cortex Phellodendris 410 Radix Et Rhizoma Rhei 210

They clothing powder 310 Radix Paeoniae Rubra 450.

In the above-mentioned three assembly sides the 8 flavor prepared slices of Chinese crude drugs such as Flos Lonicerae, Fructus Forsythiae, Flos Chrysanthemi are cleaned, combination in proportion, decoct with water 2 times, each 2 hours, merge 2 times decoction liquor, filter, and concentrate, make into fluid extract, adopt conventional preparation technology, Chinese medicine preparation of the present invention can be made into said dosage form on any pharmaceutics, as: granule, tablet, capsule, oral liquid, pill, syrup agent, buccal tablet, effervescent tablet, dispersible tablet.

Claims (3)

1, the dermopathic medicine of a kind of treatment is characterized in that it is made up of the component of following parts by weight:

Flos Lonicerae 700-800 Fructus Forsythiae 400-500 Flos Chrysanthemi 300-400

Radix Scutellariae 300-400 Cortex Phellodendri 400-550 Radix Et Rhizoma Rhei 200-300

It clothing powder 300-400 Radix Paeoniae Rubra 300-450.

2, the dermopathic medicine of treatment according to claim 1 is characterized in that it is made up of the component of following parts by weight:

Flos Lonicerae 740-800 Fructus Forsythiae 400-460 Flos Chrysanthemi 350-400

Radix Scutellariae 300-350 Cortex Phellodendri 420-520 Radix Et Rhizoma Rhei 230-280

It clothing powder 320-380 Radix Paeoniae Rubra 350-450.

3, the dermopathic medicine of treatment according to claim 1 and 2 is characterized in that: it can be said dosage form on any pharmaceutics.