CN1557318A - Continuous release medicine composition and its preparation method - Google Patents
Continuous release medicine composition and its preparation method Download PDFInfo
- Publication number
- CN1557318A CN1557318A CNA2004100017475A CN200410001747A CN1557318A CN 1557318 A CN1557318 A CN 1557318A CN A2004100017475 A CNA2004100017475 A CN A2004100017475A CN 200410001747 A CN200410001747 A CN 200410001747A CN 1557318 A CN1557318 A CN 1557318A
- Authority
- CN
- China
- Prior art keywords
- praziquantel
- medicine
- injection
- beta cyclodextrin
- cyclodextrin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Group | The rabbit number | Natural law and Dot-ELISA response strength before and after the medication | |||||||||||||||
????0 | ????6 | ????9 | ????12 | ????15 | ????19 | ????22 | ????30 | ????40 | ????50 | ????60 | ????70 | ????80 | ????90 | ????100 | ????110 | ||
Slow releasing agent | ????5 | ????- | ????# | ????# | ????# | ????# | ????# | ????# | ????+++ | ????+++ | ????+++ | ????+++ | ????++ | ????++ | ????++ | ????+ | ????- |
Water preparation | ????5 | ????- | ????# | ????# | ????+++ | ????++ | ????+ | ????+ | ????- | ????- | ????- | ????- | ????- | ????- | ????- | ????- | ????- |
Negative rabbit number | Positive rabbit number | Protective rate (%) | |||||||||||||
Attack time (moon) | ?1 | ??2 | ??3 | ??4 | ??5 | ??1 | ??2 | ??3 | ??4 | ??5 | ??1 | ??2 | ??3 | ??4 | ??5 |
The injection-type slow releasing agent | ?3/3 | ??3/3 | ??3/3 | ??1/3 | ??0/3 | ??0/3 | ??0/3 | ??0/3 | ??2/3 | ??3/3 | ?100 | ??100 | ??100 | ??33.3 | ??0 |
Praziquantel is oral | ?3/3 | ??0/3 | ??0/3 | ??0/3 | ??0/3 | ??0/3 | ??3/3 | ??3/3 | ??3/3 | ??3/3 | ?100 | ??0 | ??0 | ??0 | ??0 |
Domestic animal | Head (only) | Injection-type slow releasing agent negative conversion rate (%) | The oral negative conversion rate of praziquantel (%) | ||||||||||
Schistosomicide | Taeniasis | Schistosomicide | Taeniasis | ||||||||||
1 month | 2 months | 3 months | 1 month | 2 months | 3 months | 1 month | 2 months | 3 months | 1 month | 2 months | 3 months | ||
Cattle | ????500 | ???100 | ???100 | ???100 | ????/ | ????/ | ????/ | ???100 | ????0 | ????0 | ????/ | ????/ | ????/ |
Sheep | ????20 | ????/ | ????/ | ????/ | ???100 | ???100 | ???100 | ????/ | ????/ | ????/ | ???100 | ????0 | ????0 |
Pig | ????30 | ????/ | ????/ | ????/ | ???100 | ???100 | ???100 | ????/ | ????/ | ????/ | ???100 | ????0 | ????0 |
Canis familiaris L. | ????20 | ????/ | ????/ | ????/ | ???100 | ???100 | ???100 | ????/ | ????/ | ????/ | ???100 | ????0 | ????0 |
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200410001747 CN1269481C (en) | 2004-01-20 | 2004-01-20 | Continuous release medicine composition and its preparation method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200410001747 CN1269481C (en) | 2004-01-20 | 2004-01-20 | Continuous release medicine composition and its preparation method |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1557318A true CN1557318A (en) | 2004-12-29 |
CN1269481C CN1269481C (en) | 2006-08-16 |
Family
ID=34350638
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 200410001747 Expired - Fee Related CN1269481C (en) | 2004-01-20 | 2004-01-20 | Continuous release medicine composition and its preparation method |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN1269481C (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107961277A (en) * | 2016-10-20 | 2018-04-27 | 王腊俊 | A kind of compound medicine for treating swine taeniasis |
CN109432440A (en) * | 2018-11-30 | 2019-03-08 | 佛山科学技术学院 | A kind of praziquantel hydroxypropyl cyclodextrin inclusion and its preparation method and application |
-
2004
- 2004-01-20 CN CN 200410001747 patent/CN1269481C/en not_active Expired - Fee Related
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107961277A (en) * | 2016-10-20 | 2018-04-27 | 王腊俊 | A kind of compound medicine for treating swine taeniasis |
CN109432440A (en) * | 2018-11-30 | 2019-03-08 | 佛山科学技术学院 | A kind of praziquantel hydroxypropyl cyclodextrin inclusion and its preparation method and application |
CN109432440B (en) * | 2018-11-30 | 2022-04-26 | 佛山科学技术学院 | Praziquantel hydroxypropyl cyclodextrin inclusion compound and preparation method and application thereof |
Also Published As
Publication number | Publication date |
---|---|
CN1269481C (en) | 2006-08-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Zhejiang Rongyao Chemical Co., Ltd. Assignor: Zhejiang Academy of Agricultural Sciences Contract fulfillment period: 2007.8.16 to 2013.8.15 contract change Contract record no.: 2009330001788 Denomination of invention: Continuous release medicine composition and its preparation method Granted publication date: 20060816 License type: Exclusive license Record date: 2009.8.3 |
|
LIC | Patent licence contract for exploitation submitted for record |
Free format text: EXCLUSIVE LICENSE; TIME LIMIT OF IMPLEMENTING CONTACT: 2007.8.16 TO 2013.8.15; CHANGE OF CONTRACT Name of requester: ZHEJIANG RONGYAO CHEMICAL INDUSTRY CO., LTD. Effective date: 20090803 |
|
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20060816 Termination date: 20140120 |