CN1555828A - Bone strengthening marrow fortifing pill for treating osteoporosis comprehensive syndrome and its preparation method - Google Patents

Bone strengthening marrow fortifing pill for treating osteoporosis comprehensive syndrome and its preparation method Download PDF

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Publication number
CN1555828A
CN1555828A CNA2003101146619A CN200310114661A CN1555828A CN 1555828 A CN1555828 A CN 1555828A CN A2003101146619 A CNA2003101146619 A CN A2003101146619A CN 200310114661 A CN200310114661 A CN 200310114661A CN 1555828 A CN1555828 A CN 1555828A
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pill
fine powders
mixing fine
fortifing
fructus schisandrae
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CNA2003101146619A
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Chinese (zh)
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孙坤元
孙健刚
孙健锋
李兴芝
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Abstract

A Chinese medicine in the form of pills for treating osteoporosis syndrome is prepared from 4 Chinese-medicinal materials including musk, schisandra fruit, epimedium, etc through honeying, pulverizing and pilling.

Description

A kind of bone strengthening marrow fortifing pill and preparation method for the treatment of osteoporosis syndrome
Technical field
The present invention relates to a kind of medicine for the treatment of osteoporosis syndrome and preparation method thereof, particularly a kind of bone strengthening marrow fortifing pill and preparation method for the treatment of osteoporosis syndrome.
Background technology
Osteoporosis syndrome is the commonly encountered diseases of world's middle-aged and elderly people, and special in the area and menopausal women of aged tendency of population, sickness rate is higher, and obviously rises with the increase incidence probability at age.According to statistics, the old people of the present over-65s of China accounts for 1.2 hundred million, and the patient who suffers from osteoporosis syndrome accounts for 90%, therefore, prevents and treats osteoporosis and be defying age, life lengthening, the warrantor very important and urgent research topic of quality of life.The pathological changes essence of osteoporosis syndrome is that the differentiation function of bone marrow goes down, expenditure reduces and the decline of bone-forming effect to cause calcareous getting, and bone-loss, bone destruction, the reduction of sclerotin intensity etc., modal symptom is to cause osteoporotic fracture, seriously influence human longevity and health, this is not only the human major reason of decline early, and brings great misery and financial burden for family and society.Cellular metabolism by life sciences is learned reckoning, the cell of human body goes down to posterity 60 times in life, and each cycle is 2.4 years, and the least life of old friend's class is 144 years, and the mankind fail to reach this basic life-span, and its main cause just is the decline in advance of bone marrow differentiation function.Think with regard to motherland's Chinese medicine, " the kidney being the origin of congenital constitution, kidney governing bones, bone is given birth to marrow, marrow hemopoietic ", all kinds of tangible cells of human body particularly immunocyte all derive from bone marrow, and therefore, the control osteoporosis syndrome stresses again to start with from strong kidney.At present the medicine of treatment osteoporosis syndrome is a lot, and as calcium preparation, estrogen and vitamin D etc., though these medicines have certain curative effect, because of itself side effect is big, uncertain therapeutic efficacy is cut, and is difficult to promote in clinical practice.
Summary of the invention
The objective of the invention is to inquire into and a kind ofly start with, make the human body kidney qi fill Sheng, delay naturally-aged, a kind of bone strengthening marrow fortifing pill for the treatment of osteoporosis syndrome of control pathology decline from the temperature compensation kidney qi.
Another object of the present invention is to prepare the method for this bone strengthening marrow fortifing pill.
For reaching above purpose, the technical solution adopted in the present invention is: the bone strengthening marrow fortifing pill of this treatment osteoporosis syndrome, it is characterized in that it comprises Moschus, Fructus Schisandrae Chinensis, Herba Epimedii, Rhizoma Drynariae, Radix Rehmanniae Preparata composition, the proportioning between the each component is: 1 part in Moschus, Fructus Schisandrae Chinensis 10-20 part, Herba Epimedii 10-15 part, Rhizoma Drynariae 10-20 part, Radix Rehmanniae Preparata 10-20 part.
Its preparation process is: after above-mentioned each component is taken by weighing, produce into pill through following steps:
(1), refined honey: select milky white, yellowish, distinguish the flavor of sweet, no foreign odor, free from admixture, thick Mel as lipoid, dissolve with straight fire heating, remove dead honeybee, impurity, put pot internal heating again to boiling, at any time drag for floating foam and impurity, boil off moisture gradually, general refining is not advisable to having tangible steam, centre to churn red foam, puts cooling at last.
(2), pulverize: the Impurity removal in the each component, earlier Fructus Schisandrae Chinensis, Herba Epimedii, Rhizoma Drynariae mixed powder are broken into mixing fine powders, again Radix Rehmanniae Preparata is mixed with Fructus Schisandrae Chinensis, Herba Epimedii, Rhizoma Drynariae mixing fine powders and roll in flakes, put under the sunlight and dry, be ground into mixing fine powders once more after doing, the mixing fine powders that will be ground into is once more put in the container and (is not used ironware) again, pour Moschus powder rapidly into, be stirred into total mixing fine powders, in total mixing fine powders and cooling honey is that 1: 1 ratio adds Mel and fully mixes, the patent medicine that stirs sticks together, and messenger drug sticks together inside and outside moist, the color and luster unanimity.(refined honey is advisable with cold to tepor in order to avoid overheated, in order to avoid drug volatilization lost efficacy).
(3), pill: earlier dip in pill oil (be one jin in Oleum Sesami, be heated to and boil, add clean Cera Flava and dissolve for three liang, treat its cooling) with two palms, the medicine of getting 9 grammes per square metres sticks together and puts in the palm, with the little finger of toe side firmly before and after stranding, round, honeyed pill, every heavy 9 restrains.
Prescription pharmacology of the present invention is:
Radix Rehmanniae Preparata: enriching yin and nourishing kidney, fill out bone marrow, promoting generation of vital essence and blood.
Rhizoma Drynariae: the kidney invigorating, strengthening bone and muscle, promoting blood circulation and stopping pain.
Herba Epimedii: bone and muscle strengthening, the benefit gate of vitality.
Fructus Schisandrae Chinensis: nourishing kidney, astringe the lung, arresting seminal emission, antidiarrheal.
Moschus: the collateral dredging of having one's ideas straightened out, promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain.
All medicines are collaborative, form the effect of enriching yin and nourishing kidney, the strong marrow of bone strengthening, make that human body Yuanyang is firm, bone marrow enriches, healthy and strong, the middle gas foot of skeleton, defend in gas-solid, exopathogen can not pass.
Instructions of taking: eliminating cold for resuscitation mouth of a river clothes, every day secondary, sooner or later each once, each 1.
Through clinical practice, treat 25 examples altogether, total effective 23 examples, effective percentage is 92%; In effective case, effect shows author's 18 examples, and obvious effective rate is 72%; Invalid 2 examples, inefficiency are 8%.
Beneficial effect of the present invention is that expense is low, produces easily, and the osteoporosis syndrome of middle-aged and elderly people is had the obvious treatment effect.
Embodiment 1:
Take by weighing 1 part in Moschus, 19 parts of Fructus Schisandrae Chinensis, 10 parts of Herba Epimedii, 18 parts of Rhizoma Drynariae, 12 parts of Radix Rehmanniae Preparata.Its making step is same as above, mainly comprises: 1, refined honey; 2, pulverize; 3, pill.
Classic case Zhang Cuizhen takes, and effect is remarkable.
Zhang Cuizhen, woman, 68 years old, Yang Li town, Laicheng district Sun Wangshi people from village, the pain that has a pain in the leg in JIUYUE, 97 left side, postemphasis, lose viability, can not leave the bed, pressing down commune hospital's physical therapy in October, 98, DeGrain, when going to a doctor to the People's Hospital, Laicheng district, X-ray sheet report shows: a large amount of hyperosteogenys of waist 3,4 vertebral body edge, with bony spur, form waist 4-5 narrowing of intervertebral space, impression: lumbar degenerative pathological changes.In October, 2000 is oral with " bone strengthening is good for vertebra marrow ball ", pain relief after two courses of treatment (two months), transference cure after three courses of treatment (three months), the X-ray sheet shows after six months, hyperosteogeny, bony spur all disappear, strengthen a course of treatment (one month), recover viability fully, and can do farm work in power down.
Similar case also has 7 examples.Wherein 4 examples have remarkable result; 2 examples are effective, but do not cure; 1 example is invalid, and symptom does not have significant change.
Embodiment 2
Take by weighing 1 part in Moschus, 11 parts of Fructus Schisandrae Chinensis, 14 parts of Herba Epimedii, 12 parts of Rhizoma Drynariae, 19 parts of Radix Rehmanniae Preparata.Its making step is with above-mentioned.
Classic case Song makes sweet smell take, and effect is remarkable.
Song Lingfen, woman, 54 years old, Yang Li town, Laicheng district Sun Wangshi people from village, in March, 2000 right side have a pain in the leg, increase the weight of when working, after cause difficulty in walking, when going to a doctor in the People's Hospital, Laicheng district, the X-ray sheet shows, lumbar vertebra hyperosteogeny, the 2-3 joint is attached most importance to, and June calendar year 2001 is oral with " bone strengthening marrow fortifing pill ", pain relief after two courses of treatment (two months), three courses of treatment (three months), the back transference cure was strengthened a course of treatment (one month), the X-ray check, the hyperosteogeny phenomenon disappears, and does housework, does farm work all as ordinary person.
Similar case also has 8 examples.Wherein 5 examples have remarkable result; 1 example is effective, but not good entirely; 1 example is invalid, and symptom does not have significant change.
Embodiment 3
Take by weighing 1 part in Moschus, 15 parts of Fructus Schisandrae Chinensis, 12 parts of Herba Epimedii, 15 parts of Rhizoma Drynariae, 15 parts of Radix Rehmanniae Preparata.Its making step is same as above.
Classic case king likes that English takes, and effect is remarkable.
Wang Aiying, the woman, 41 years old, sloping people from village of Zhai Li town waterlogging, the patient began neck 97 year autumn and aches, rotate difficulty, 99 years both shoulders arthralgias, the X-ray sheet shows hyperosteogeny of cervical vertebra in 5,6,7, in August, 2002 is oral with " bone strengthening marrow fortifing pill ", 4 courses of treatment, (four months) symptom all disappeared, and took care of oneself productive labor such as ordinary person.
Similar case also has 7 examples.Wherein 6 examples have remarkable result; 1 example is effective, but not good entirely.

Claims (2)

1, a kind of bone strengthening marrow fortifing pill for the treatment of osteoporosis syndrome, it is characterized in that it comprises Moschus, Fructus Schisandrae Chinensis, Herba Epimedii, Rhizoma Drynariae, Radix Rehmanniae Preparata composition, the proportioning between the each component is: 1 part in Moschus, Fructus Schisandrae Chinensis 10-20 part, Herba Epimedii 10-15 part, Rhizoma Drynariae 10-20 part, Radix Rehmanniae Preparata 10-20 part.
2, a kind of preparation method for the treatment of the bone strengthening marrow fortifing pill of osteoporosis syndrome is characterized in that it may further comprise the steps:
(1), refined honey: select milky white, yellowish, distinguish the flavor of sweet, no foreign odor, free from admixture, thick Mel as lipoid, dissolve with straight fire heating, remove dead honeybee, impurity, put pot internal heating again to boiling, at any time drag for floating foam and impurity, boil off moisture gradually, general refining is not advisable to having tangible steam, centre to churn red foam, puts cooling at last.
(2), pulverize: the Impurity removal in the each component, earlier Fructus Schisandrae Chinensis, Herba Epimedii, Rhizoma Drynariae mixed powder are broken into mixing fine powders, again Radix Rehmanniae Preparata is mixed with Fructus Schisandrae Chinensis, Herba Epimedii, Rhizoma Drynariae mixing fine powders and roll in flakes, put under the sunlight and dry, be ground into mixing fine powders once more after doing, the mixing fine powders that will be ground into is once more put in the container again, pour Moschus powder rapidly into, be stirred into total mixing fine powders, in total mixing fine powders and cooling honey is that 1: 1 ratio adds Mel and fully mixes, the patent medicine that stirs sticks together, and messenger drug sticks together inside and outside moist, the color and luster unanimity.
(3), pill: earlier dip in pill oil with two palms, the medicine of getting 9 grammes per square metres sticks together and puts in the palm, with the little finger of toe side firmly before and after stranding, round, honeyed pill, every heavy 9 restrain.
CNA2003101146619A 2003-12-30 2003-12-30 Bone strengthening marrow fortifing pill for treating osteoporosis comprehensive syndrome and its preparation method Pending CN1555828A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101537170B (en) * 2008-03-17 2012-05-30 哈药集团制药六厂 Compound for preventing osteoporosis and osteoarthrosis
CN108014122A (en) * 2018-02-06 2018-05-11 中国中医科学院中医基础理论研究所 Fructus Schisandrae Polysaccharide is preparing the purposes in being used to treat the medicine of osteoporosis

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101537170B (en) * 2008-03-17 2012-05-30 哈药集团制药六厂 Compound for preventing osteoporosis and osteoarthrosis
CN108014122A (en) * 2018-02-06 2018-05-11 中国中医科学院中医基础理论研究所 Fructus Schisandrae Polysaccharide is preparing the purposes in being used to treat the medicine of osteoporosis

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