CN1554295A - Use of notoginseng extract as free radical cleaning agent of tobacco product and relative tobacco product - Google Patents
Use of notoginseng extract as free radical cleaning agent of tobacco product and relative tobacco product Download PDFInfo
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- CN1554295A CN1554295A CNA2003101041655A CN200310104165A CN1554295A CN 1554295 A CN1554295 A CN 1554295A CN A2003101041655 A CNA2003101041655 A CN A2003101041655A CN 200310104165 A CN200310104165 A CN 200310104165A CN 1554295 A CN1554295 A CN 1554295A
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- free radical
- tobacco product
- tobacco
- pipe tobacco
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- 239000000284 extract Substances 0.000 title claims abstract description 56
- 235000019505 tobacco product Nutrition 0.000 title claims abstract description 24
- 150000003254 radicals Chemical class 0.000 title abstract description 25
- 241000180649 Panax notoginseng Species 0.000 title abstract description 10
- 235000003143 Panax notoginseng Nutrition 0.000 title abstract description 9
- 239000012459 cleaning agent Substances 0.000 title 1
- 241000208125 Nicotiana Species 0.000 claims abstract description 24
- 235000002637 Nicotiana tabacum Nutrition 0.000 claims abstract description 24
- 235000019504 cigarettes Nutrition 0.000 claims abstract description 19
- 244000131316 Panax pseudoginseng Species 0.000 claims description 14
- 235000003181 Panax pseudoginseng Nutrition 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 11
- 229940123457 Free radical scavenger Drugs 0.000 claims description 7
- 239000002516 radical scavenger Substances 0.000 claims description 7
- 239000002904 solvent Substances 0.000 claims description 7
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 239000002798 polar solvent Substances 0.000 claims description 3
- 239000009759 San-Chi Substances 0.000 claims description 2
- 235000019506 cigar Nutrition 0.000 abstract description 2
- 231100000053 low toxicity Toxicity 0.000 abstract description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 17
- 239000012071 phase Substances 0.000 description 17
- 239000007789 gas Substances 0.000 description 9
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 description 8
- 239000003546 flue gas Substances 0.000 description 8
- 238000012360 testing method Methods 0.000 description 7
- 238000004435 EPR spectroscopy Methods 0.000 description 5
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 4
- 230000005298 paramagnetic effect Effects 0.000 description 4
- 239000003963 antioxidant agent Substances 0.000 description 3
- 230000003078 antioxidant effect Effects 0.000 description 3
- 235000006708 antioxidants Nutrition 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 239000007792 gaseous phase Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 229930182490 saponin Natural products 0.000 description 3
- 150000007949 saponins Chemical class 0.000 description 3
- 235000017709 saponins Nutrition 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 101710112752 Cytotoxin Proteins 0.000 description 2
- UFNDONGOJKNAES-UHFFFAOYSA-N Ginsenoside Rb1 Natural products CC(=CCCC(C)(OC1OC(COC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O)C3CCC4(C)C3C(O)CC5C6(C)CCC(OC7OC(CO)C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O)C(C)(C)C6CC(O)C45C)C UFNDONGOJKNAES-UHFFFAOYSA-N 0.000 description 2
- 229910002092 carbon dioxide Inorganic materials 0.000 description 2
- 239000001569 carbon dioxide Substances 0.000 description 2
- 231100000433 cytotoxic Toxicity 0.000 description 2
- 231100000599 cytotoxic agent Toxicity 0.000 description 2
- 230000001472 cytotoxic effect Effects 0.000 description 2
- 239000002619 cytotoxin Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- GZYPWOGIYAIIPV-JBDTYSNRSA-N ginsenoside Rb1 Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O)O[C@@](C)(CCC=C(C)C)[C@@H]1[C@@H]2[C@@]([C@@]3(CC[C@H]4C(C)(C)[C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O5)O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O5)O)CC[C@]4(C)[C@H]3C[C@H]2O)C)(C)CC1)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O GZYPWOGIYAIIPV-JBDTYSNRSA-N 0.000 description 2
- YURJSTAIMNSZAE-HHNZYBFYSA-N ginsenoside Rg1 Chemical compound O([C@@](C)(CCC=C(C)C)[C@@H]1[C@@H]2[C@@]([C@@]3(C[C@@H]([C@H]4C(C)(C)[C@@H](O)CC[C@]4(C)[C@H]3C[C@H]2O)O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)C)(C)CC1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O YURJSTAIMNSZAE-HHNZYBFYSA-N 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 239000003595 mist Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 239000000779 smoke Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- VCUVETGKTILCLC-UHFFFAOYSA-N 5,5-dimethyl-1-pyrroline N-oxide Chemical compound CC1(C)CCC=[N+]1[O-] VCUVETGKTILCLC-UHFFFAOYSA-N 0.000 description 1
- 241000219226 Acer truncatum Species 0.000 description 1
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 240000005373 Panax quinquefolius Species 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 206010046788 Uterine haemorrhage Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 150000001335 aliphatic alkanes Chemical group 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- -1 arasaponin R1 Chemical class 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N benzene Substances C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 229960002246 beta-d-glucopyranose Drugs 0.000 description 1
- 208000034158 bleeding Diseases 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 239000000039 congener Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- OORMXZNMRWBSTK-LGFJJATJSA-N dammarane Chemical compound C1CCC(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@H]([C@H](C)CCCC(C)C)[C@H]4CC[C@@H]3[C@]21C OORMXZNMRWBSTK-LGFJJATJSA-N 0.000 description 1
- 238000005238 degreasing Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000003480 eluent Substances 0.000 description 1
- 238000010828 elution Methods 0.000 description 1
- 239000000469 ethanolic extract Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000012458 free base Substances 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 201000005202 lung cancer Diseases 0.000 description 1
- 208000020816 lung neoplasm Diseases 0.000 description 1
- 230000005291 magnetic effect Effects 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- SHCBCKBYTHZQGZ-CJPZEJHVSA-N protopanaxatriol Chemical group C1C[C@H](O)C(C)(C)[C@@H]2[C@@H](O)C[C@@]3(C)[C@]4(C)CC[C@H]([C@@](C)(O)CCC=C(C)C)[C@H]4[C@H](O)C[C@@H]3[C@]21C SHCBCKBYTHZQGZ-CJPZEJHVSA-N 0.000 description 1
- BBEUDPAEKGPXDG-UHFFFAOYSA-N protopanaxatriol Natural products CC(CCC=C(C)C)C1CCC2(C)C1C(O)CC3C4(C)CCC(O)C(C)(C)C4C(O)CC23C BBEUDPAEKGPXDG-UHFFFAOYSA-N 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 150000008130 triterpenoid saponins Chemical class 0.000 description 1
- 208000019553 vascular disease Diseases 0.000 description 1
Landscapes
- Manufacture Of Tobacco Products (AREA)
Abstract
The present invention relates to the application of notoginseng extract as the free radical eliminating agent for tobacco products. The notoginseng extract may be notoginseng root and stem extract and/or notoginseng leaf extract; and the tobacco products include cigarette, cigar and tobacco shred. For cigarette, the notoginseng extract may be added into its shred, with the added amount being 0.02-0.06% of shred, or its filter tip. The present invention also relates to the tobacco products with the notoginseng extract added. The notoginseng extract has excellent application foreground in developing low-toxicity and low-free radical safe tobacco products.
Description
Affiliated technical field
The invention belongs to the natural plant extract in the tobacco product Application in Manufacturing Industry.
Background technology
People aspirate the flue gas that the tobacco product burning is produced, but have the free radical of cytotoxic molecule in the flue gas.These cytotoxic molecules bring out cancer in smoker's body, particularly lung cancer.The safety-type tobacco product of Development and Production low free radical is the important R﹠D direction of tobacco product industry in recent years.
Araliaceae ginseng plant pseudo-ginseng Panax notoginseng (Burk.) F.H.Chen, at the applicating history in existing more than 600 year of China, its main active is the total soap formula of pseudo-ginseng (Panaxnotoginsenoside, PNS), contain sanchinoside E1, Rb2, Rc, Rd, Rf, Rg1, Rg2, Rh1, with more than 20 kind of saponins such as arasaponin R1, R2, R3, R4, R6, all belong to the dammarane type four-ring triterpenoid saponin, wherein the content with sanchinoside E1, Rg1 and arasaponin R1 is the highest.Arasaponin R1 is the characteristic chemical constituent that pseudo-ginseng is different from congener genseng, American Ginseng, and its structure is 20 (S) Protopanaxatriol 6-[O-β-D xylopyranosyl (I → 2) β-D-glucopyranose]-20-O-β-D-glucopyanoside.Research data shows: the content of arasaponin R1 in notoginseng total saponin is being 6.00-11.5%.Pseudo-ginseng has medical value, the stasis of blood of loosing hemostasis, and detumescence ding-tong is used for clinically spit blood, spits blood, has blood in stool, uterine bleeding, the shouting pain of chest abdomen hemostasis, and tumbling and swelling, traumatism and bleeding and carbuncle swell.Also be used for coronary heart disease, angina pectoris and cranial vascular disease etc.But Notogineng Extract as the free radical scavenger in the tobacco product suction, be there is no bibliographical information so far in the world wide.
Summary of the invention
The object of the present invention is to provide the new purposes of pseudo-ginseng and by product that this purposes obtained, purposes and the corresponding tobacco product of Notogineng Extract as the tobacco product free radical scavenger promptly is provided, with the regional advantages of performance natural plant resource, satisfy pressing for of cigarette industry exploitation low free radical safety type cigarette.
The technical scheme of purposes invention is among the present invention: the extract of pseudo-ginseng is used as free radical scavenger in the tobacco product suction.Said tobacco product can be a cigarette, also can be cigar or tobacco pipe pipe tobacco.If cigarette, then the extract of pseudo-ginseng can add in the pipe tobacco of cigarette, also can add in the filter tip of cigarette.The extract of said pseudo-ginseng can be the extract of pseudo-ginseng rhizome, also can be the extract of sanchi leaf.
The Notogineng Extract that is added can be the extract under the multiple composition admixture, also can be the mixture of isolated a kind of extract or more than one extracts the extract under multiple composition admixture.
The approach that obtains Notogineng Extract has multiple, for example can obtain by polar solvent such as alcohol or aqueous alcohols solvent extraction.The alcohol that is used as solvent especially can be ethanol.This extract also can obtain by supercritical carbon dioxide extracting.Certainly also can carry out supercritical carbon dioxide extracting more earlier after polar solvent extracts obtains.
The method of the one-tenth branch of extraction and separation Notogineng Extract is a prior art, visible " pseudo-ginseng---modern scientific research and application " book chapter 1 of its report (Yunnan science and technology publishing house in December, 1996 front page, Wei Junxian, Du Yuanchong write).
If Notogineng Extract is added in the pipe tobacco of cigarette, can roll in the process at the pipe tobacco of production of cigarettes and implement.Be added into the Notogineng Extract in the pipe tobacco, can account for 0.02%～0.06% of pipe tobacco weight, be preferably and account for 0.03%～0.05% of pipe tobacco weight.Notogineng Extract can be dissolved in the solvent, the solvent that is dissolved with Notogineng Extract is sprayed on the pipe tobacco, evaporate said solvent subsequently.
Product of the present invention, the tobacco product that is obtained by above-mentioned Notogineng Extract purposes invention exactly.
The anti-oxidant behavior of antioxidant has certain selectivity.The main component of the free radical in the smoking gas phase is alkanes and alcoxyl type free base.Will effectively remove the free radical in the flue gas, selected antioxidant should have versatility, promptly has the ability of removing multiple free radical.Patent applicant's series of experimental research result shows that the Notogineng Extract of adding can be removed the free radical in the flue gas effectively when tobacco product aspirates, and promptly Notogineng Extract meets the requirement of removing free radical in the tobacco.Add the tobacco product of Notogineng Extract and comparing of not adding, no matter the molecule of cytotoxin free radical in the former flue gas is a gas phase or a phase, can both significantly be reduced.
The invention has the beneficial effects as follows,, opened up a new application for pseudo-ginseng has excavated new health purpose.Notogineng Extract is as the tobacco product free radical scavenger, and effect is obvious, and exploitation low toxicity safety-type tobacco product harmful, low free radical is had good application prospects.
Description of drawings
Fig. 1 is the paramagnetic resonance signal recording curve of certain blank test.
Fig. 2 is the paramagnetic resonance signal recording curve of certain clearance test.
The present invention is described further by embodiment below, but scope of invention is not subjected to the limitation of illustrated embodiment.
The specific embodiment
See following embodiment.
(1) preparation of Notogineng Extract
Adopt solvent-resin method preparation, see: Tang's light, " Chinese patent drug ", 1990,12 (8): P5.Process: pseudo-ginseng rhizome powder → Me
2The CO degreasing, alcohol extract → ethanol extract → recovery EtOH, the pretreated D-101 type macroporous absorbent resin → water elution that is dissolved in water → crosses is use up non-saponin polar components such as free sugar, EtOH wash-out → EtOH eluent → activated carbon decolorizing, and filtration → filtrate → drying → must extract.
(2) in the pipe tobacco of cigarette or filter tip, add the extract that is obtained
Extract rolled in the pipe tobacco of production of cigarettes add pipe tobacco in the process.Be added into the Notogineng Extract in the pipe tobacco, account for 0.04% of pipe tobacco weight.Concrete grammar is that the said extracted thing of first pseudo-ginseng is dissolved in the ethanol, is sprayed at the ethanol that is dissolved with the acer truncatum extract on the pipe tobacco or in the filter tip, ethanol is evaporated subsequently.
(3) the removing effect of free radical in the cigarette smoke
The detection of free radical has multiple known method to adopt, electron spin resonance (ESR) for example, chromatography, chemoluminescence method, XRF, AAS etc.One of the device people such as visible Pryor that are used for holding back cigarette smoke gas phase and grain phase free radical publication " Environmengtal Health Perspectives " (1976, vol.16, report pp161-175).
The main electron paramagnetic resonance method that adopts is tested in the process of the present invention, also uses additive method, particularly AAS simultaneously, test result has been done contrast reflected card, and the result conforms to.Used EPR spectrometer is the BKER-EMX6/1 of German BRUKER company.
1, blank test
Is the concentration adjustment of the gaseous phase free radical trapping agent DMPO in the organic solvent-benzene 20 mMs, and use 5 cigarette that are not added with Notogineng Extract (brand is " cloud and mist ") to carry out in its flue gas gas phase and catching of free radical mutually, carrying out free radical with ESR then measures, with the index of ESR signal strength signal intensity as the free radical amount, 5 times mean value is calculated in parallel determination 5 times.
2, clearance test
Use 5 cigarette that are added with Notogineng Extract (brand is " cloud and mist ") to carry out in its flue gas gas phase and grain catching of free radical mutually, repetition aforesaid operations.
The double integrator quantitative result shows, adds the cigarette of Notogineng Extract and comparing of not adding, the quantity of the molecule of cytotoxin free radical in the former flue gas, and gaseous phase free radical reduces by 31～38%, and grain phase free radical reduces by 30～35%.
Fig. 1 is the paramagnetic resonance signal recording curve of certain blank test, and wherein label is 107 to be the primary signal curve of gas phase, and label is 109 to be the double integrator curve of gas phase.Label is
*110 is the primary signal curve of grain phase, and label is the 112 double integrator curves for the grain phase.The biproduct score value of 109 curves is that the biproduct score value of 83822.140625,112 curves is 59108.027344.
Fig. 2 is the paramagnetic resonance signal recording curve of certain clearance test, and wherein label is 026 to be the primary signal curve of gas phase, and label is 028 to be the double integrator curve of gas phase.Label is
*029 is the primary signal curve of grain phase, and label is the 031 double integrator curves for the grain phase.The biproduct score value of 028 curve is that the biproduct score value of 57807.281250,031 curves is 38468.960398.
The experimental condition that obtains Fig. 1 and 2 is: sweep the collection collection of illustrative plates slowly, central magnetic field=3385.0GS sweeps wide=200.0GS, microwave frequency=9.4800GHz.
With regard to Fig. 1 and 2, the ≈ 35% of grain phase free radical reduced rate=(59108.027344-38468.960398)/59108.027344; The ≈ 31% of gaseous phase free radical reduced rate=(83822.140625-57807.281250)/83822.140625;
Claims (8)
1, Notogineng Extract is as the purposes of tobacco product free radical scavenger.
2, purposes as claimed in claim 1, wherein the extract of said pseudo-ginseng is the extract of pseudo-ginseng rhizome.
3, purposes as claimed in claim 1, wherein the extract of said pseudo-ginseng is the extract of sanchi leaf.
4, as each purposes of claim 1 to 3, wherein said Notogineng Extract obtains for extracting by polar solvent.
5, as each purposes of claim 1 to 4, Notogineng Extract is added in the pipe tobacco of cigarette, and roll in the process at the pipe tobacco of production of cigarettes and to implement, the Notogineng Extract that is added in the pipe tobacco accounts for 0.02%～0.06% of pipe tobacco weight.
6, purposes as claimed in claim 5, the Notogineng Extract that is added in the pipe tobacco accounts for 0.03%～0.05% of pipe tobacco weight.
7, purposes as claimed in claim 6 is dissolved in Notogineng Extract in the solvent, and the solvent that is dissolved with Notogineng Extract is sprayed on the pipe tobacco, evaporates said solvent subsequently.
8, be added with the tobacco product of Notogineng Extract as free radical scavenger.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200310104165 CN1253111C (en) | 2003-12-23 | 2003-12-23 | Use of notoginseng extract as free radical cleaning agent of tobacco product and relative tobacco product |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200310104165 CN1253111C (en) | 2003-12-23 | 2003-12-23 | Use of notoginseng extract as free radical cleaning agent of tobacco product and relative tobacco product |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1554295A true CN1554295A (en) | 2004-12-15 |
| CN1253111C CN1253111C (en) | 2006-04-26 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200310104165 Expired - Lifetime CN1253111C (en) | 2003-12-23 | 2003-12-23 | Use of notoginseng extract as free radical cleaning agent of tobacco product and relative tobacco product |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101390658B (en) * | 2008-11-07 | 2011-12-28 | 云南烟草科学研究院 | Cigarette composite tip containing plant saponin extract |
| CN106617268A (en) * | 2017-01-26 | 2017-05-10 | 白山市禄程农林科技有限公司 | Panax notoginseng leaf non-tobacco cigarette and preparation method thereof |
| CN106617269A (en) * | 2017-01-26 | 2017-05-10 | 白山市禄程农林科技有限公司 | Panax notoginseng leaf/panax quinquefolius leaf non-tobacco cigarette and preparation method thereof |
| CN106617270A (en) * | 2017-01-26 | 2017-05-10 | 白山市禄程农林科技有限公司 | Radix acanthopanacis senticosi/sanchi leaves non-tobacco cigarette and preparing method thereof |
| CN107981400A (en) * | 2017-12-08 | 2018-05-04 | 江西中烟工业有限责任公司 | A kind of production method of Chinese medicine cigarette and its Chinese medicine additive |
-
2003
- 2003-12-23 CN CN 200310104165 patent/CN1253111C/en not_active Expired - Lifetime
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101390658B (en) * | 2008-11-07 | 2011-12-28 | 云南烟草科学研究院 | Cigarette composite tip containing plant saponin extract |
| CN106617268A (en) * | 2017-01-26 | 2017-05-10 | 白山市禄程农林科技有限公司 | Panax notoginseng leaf non-tobacco cigarette and preparation method thereof |
| CN106617269A (en) * | 2017-01-26 | 2017-05-10 | 白山市禄程农林科技有限公司 | Panax notoginseng leaf/panax quinquefolius leaf non-tobacco cigarette and preparation method thereof |
| CN106617270A (en) * | 2017-01-26 | 2017-05-10 | 白山市禄程农林科技有限公司 | Radix acanthopanacis senticosi/sanchi leaves non-tobacco cigarette and preparing method thereof |
| CN107981400A (en) * | 2017-12-08 | 2018-05-04 | 江西中烟工业有限责任公司 | A kind of production method of Chinese medicine cigarette and its Chinese medicine additive |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1253111C (en) | 2006-04-26 |
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