CN1546132A - Prescription of Shiliu stomach-strengthening capsule and its preparing process and formulation - Google Patents
Prescription of Shiliu stomach-strengthening capsule and its preparing process and formulation Download PDFInfo
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- CN1546132A CN1546132A CNA2003101171362A CN200310117136A CN1546132A CN 1546132 A CN1546132 A CN 1546132A CN A2003101171362 A CNA2003101171362 A CN A2003101171362A CN 200310117136 A CN200310117136 A CN 200310117136A CN 1546132 A CN1546132 A CN 1546132A
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Abstract
The invention discloses a Granada capsule fro treating gastritis, gastric ulcer, dyspepsia and anorexia, which is prepared from pomegranate seed, Cinnamomum cassia, cardamorn, long pepper and safflower.
Description
The present invention produces a kind of function that the stomach warming benefit is fiery, change stagnates dehumidifying, temperature is promoted blood circulation that has, and is used for the treatment of prescription and the preparation technology and the dosage form thereof of disease medicines such as gastritis, gastric ulcer, dyspepsia, inappetence, cold diarrhoea.
The Cortex Cinnamomi in the selected Yunnan of the present invention, Fujian, Guangdong, Guangxi; The Fructus Piperis Longi in Yunnan, Guangdong; Fructus Amomi Rotundus that introduce a fine variety in Yunnan, Guangdong or amomum compactum Soland ex Maton; With the Flos Carthami of ground productions such as Tibet, Qinghai, Gansu, Sichuan, Henan, and the famous and precious raw materials such as pomegranate of Punicaceae plant.
These medical material physicochemical properties are respectively: Semen Granati, warm in nature, can promote the stomach temperature, cure mainly Baconic's sympotoms caused by cold factors, all gastropathy of cold syndrome of the stomach disease; Cortex Cinnamomi: extremely hot in nature, the energy dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow cures mainly insufficiency of vital energy and blood, sexual impotence, cold womb, chills and pain of the waist and kness, dizziness due to yang deficiency, conjunctival congestion pharyngalgia etc.; Flos Carthami: warm in nature, energy promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing cures mainly dysmenorrhea due to blood stasis, traumatic injury, arthralgia, arthritis etc.; Fructus Piperis Longi: hot in nature, can warming spleen and stomach for dispelling cold, therapeutic method to keep the adverse QI flowing downwards pain relieving cures mainly coldness and pain in the epigastrium, vomits, has loose bowels, migraine, toothache etc.; Fructus Amomi Rotundus: warm in nature, can removing dampness disappear painful abdominal mass, circulation of qi promoting warming middle-JIAO, appetite-stimulating indigestion-relieving, cure mainly turbid damp obstructing in middle-JIAO, anorexia, hygropyrexia from the beginning of, chest and abdomen swelling and pain, gastritis, gastric ulcer, food stagnation do not disappear etc.
Show according to clinical experimental study report: test group 600 examples, inpatient 430 examples, outpatient service 170 examples with pomegranate stomachic capsule for treating gastritis, gastric ulcer; Age, in 18-65 year, the mean age was 32.9 years old respectively, gastritis 300 examples wherein, and 1-5 was 87 examples to the course of disease with interior 150 examples in 1 year, was 63 examples more than 5 years.Gastric ulcer patient 300 examples, 1-5 139 examples were 38 examples more than 5 years to the course of disease with interior 123 examples in 1 year, and five weeks were a course of treatment, and total effects rate gastritis sufferer total effective rate is 87.67%, and is higher by 1.67% than matched group.Gastric ulcer patient total effective rate is 81%, and is higher by 6% than matched group.
The present invention has done great change except that having done the reasonable adjustment on preparation technology and dosage form on prescription.Traditional pomegranate stomachic looses, and is to produce in workshop-based mode, and dosage form is the type dosage form of loosing, and extremely inconvenient patient takes, and storage life is also short, small scale, of poor quality.According to the problem that exists, the present invention in conjunction with the requirement of modern drug development, has developed new preparation technology and dosage form on the basis of these tradition Tibetan medicine characteristics of reservation.
Pomegranate stomachic capsule of the present invention technological process is: selected → roguing → crushing fine powder → as to sieve → mixing → filled capsules → the capsule press mold → aluminum-plastic packaged → quality inspection → finished product packing → stock.
After the improvement of the present invention through preparation technology and dosage form, this product has not only kept the curative effect of traditional Tibetan medicine.Help mechanization production again, reduce cost.Outstanding capsule preparations had both made things convenient for the patient to obey to be had, has prolonged the holding time again, stablized product quality.
Nine times the pomegranate stomachic capsule stability examined through three batches by " new drug approval method ".Last 18 months and obtain up to a hundred data, its character, discriminating, the equal conformance with standard regulation of inspection, stability is very strong.
Claims (5)
1, forms by rare medicinal herbs compatibilities such as Semen Granati, Cortex Cinnamomi, Fructus Amomi Rotundus, Fructus Piperis Longi, Flos Carthamis, through selected roguing, pulverize, sieve, mixing, incapsulate, promptly get and be capsule formulation.
2, according to claim 1, prescription is characterised in that: Semen Granati 90-160g, Cortex Cinnamomi 20-70g, Fructus Amomi Rotundus 30-80g, Fructus Piperis Longi 10-40g, Flos Carthami 30-80g.
3, according to claim 1, with plant equipment processing, carry out mechanization production.
4, according to claim 1,3 described, preparation technology is characterised in that: picking of raw material → roguing is clean → and crushing fine powder → sieve → mixing → filled capsules → capsule pressing mold → aluminum-plastic packaged → quality inspection → finished product packing → stock.
5, according to claim 1,2,3 described, its dosage form is characterised in that: I capsule formulation, II pill, III electuary, IV oral liquid, V granule dosage form.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2003101171362A CN1546132A (en) | 2003-12-04 | 2003-12-04 | Prescription of Shiliu stomach-strengthening capsule and its preparing process and formulation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CNA2003101171362A CN1546132A (en) | 2003-12-04 | 2003-12-04 | Prescription of Shiliu stomach-strengthening capsule and its preparing process and formulation |
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| Publication Number | Publication Date |
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| CN1546132A true CN1546132A (en) | 2004-11-17 |
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| CNA2003101171362A Pending CN1546132A (en) | 2003-12-04 | 2003-12-04 | Prescription of Shiliu stomach-strengthening capsule and its preparing process and formulation |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101708200B (en) * | 2009-12-04 | 2011-06-22 | 张书勤 | External antidiarrheal for infants |
| CN103653129A (en) * | 2013-12-02 | 2014-03-26 | 南通双和食品有限公司 | Digestion improving beverage and preparation method thereof |
| CN104043081A (en) * | 2014-06-13 | 2014-09-17 | 薛枫 | Traditional Chinese composition for treating dyspepsia |
| CN104587355A (en) * | 2013-10-30 | 2015-05-06 | 刘道林 | Health-care product added with pomegranate |
| CN104740570A (en) * | 2015-03-31 | 2015-07-01 | 拉萨市林周县人民医院 | Medicament with effects of dispelling wind, eliminating dampness and relieving swelling and pain as well as preparation method and application thereof |
| CN108245651A (en) * | 2016-12-28 | 2018-07-06 | 兰州奇正生态健康品有限公司 | A kind of pharmaceutical composition with gastrointestinal tract health-care effect and preparation method thereof and purposes |
| CN111109455A (en) * | 2019-12-30 | 2020-05-08 | 夏河县羚羊生态有机燃料有限公司 | Plateau Tibetan region sheep breeding feed capable of improving cold resistance and disease resistance |
| CN112294934A (en) * | 2020-11-12 | 2021-02-02 | 成都武侯甘露海藏医院有限公司 | Tibetan medicine hexagonal pomegranate powder composition and preparation method and application thereof |
-
2003
- 2003-12-04 CN CNA2003101171362A patent/CN1546132A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101708200B (en) * | 2009-12-04 | 2011-06-22 | 张书勤 | External antidiarrheal for infants |
| CN104587355A (en) * | 2013-10-30 | 2015-05-06 | 刘道林 | Health-care product added with pomegranate |
| CN103653129A (en) * | 2013-12-02 | 2014-03-26 | 南通双和食品有限公司 | Digestion improving beverage and preparation method thereof |
| CN103653129B (en) * | 2013-12-02 | 2015-09-16 | 宁波市镇海昱达网络科技有限公司 | A kind of stomach strengthening and digestion promoting beverage and preparation method thereof |
| CN104043081A (en) * | 2014-06-13 | 2014-09-17 | 薛枫 | Traditional Chinese composition for treating dyspepsia |
| CN104740570A (en) * | 2015-03-31 | 2015-07-01 | 拉萨市林周县人民医院 | Medicament with effects of dispelling wind, eliminating dampness and relieving swelling and pain as well as preparation method and application thereof |
| CN104740570B (en) * | 2015-03-31 | 2018-04-06 | 拉萨市林周县人民医院 | Medicine acted on dispelling wind and eliminating dampness and swelling and pain relieving and its production and use |
| CN108245651A (en) * | 2016-12-28 | 2018-07-06 | 兰州奇正生态健康品有限公司 | A kind of pharmaceutical composition with gastrointestinal tract health-care effect and preparation method thereof and purposes |
| CN111109455A (en) * | 2019-12-30 | 2020-05-08 | 夏河县羚羊生态有机燃料有限公司 | Plateau Tibetan region sheep breeding feed capable of improving cold resistance and disease resistance |
| CN112294934A (en) * | 2020-11-12 | 2021-02-02 | 成都武侯甘露海藏医院有限公司 | Tibetan medicine hexagonal pomegranate powder composition and preparation method and application thereof |
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Addressee: Zhang Ling Document name: Deemed as a notice of withdrawal (Trial) |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |