CN1537580A - Honghua Qili tablet contg. safflower carthamus, and its prepn. method - Google Patents
Honghua Qili tablet contg. safflower carthamus, and its prepn. method Download PDFInfo
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- CN1537580A CN1537580A CNA031182860A CN03118286A CN1537580A CN 1537580 A CN1537580 A CN 1537580A CN A031182860 A CNA031182860 A CN A031182860A CN 03118286 A CN03118286 A CN 03118286A CN 1537580 A CN1537580 A CN 1537580A
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- notoginseng
- flos carthami
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- containing tablet
- fine powder
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Abstract
An improved Chinese medicine 'Honghua Qili tablets' for treating traumatic injury, ecchymoma and traumatic hemorrhage is prepared through superfine pulverizing of cinnabar, proportionally mixing it with others, and tabletting. Its advantages are high curative effect and high safety.
Description
Technical field
This invention relates to the processing technology technical field of Chinese patent medicine tablet, relates in particular to Flos Carthami notoginseng-containing tablet and preparation method.
Background technology
Tablet is a kind of pharmaceutical formulation commonly used, according to the relevant drug act of China, changing dosage form needs as a kind of new drug research, and the original dosage form of Flos Carthami notoginseng-containing tablet is: the Flos Carthami Anisodus carniolicoides C.Y.Wu et C.Chen, listed in national Bureau of Drugs Supervision's country's standard for traditional Chinese medicines compilation (terrestrial reference rises the GB tentative standard).The process characteristic of former dosage form is: Cinnabaris is ground into impalpable powder in the prescription, and Moschus, Borneolum Syntheticum are ground into fine powder respectively, and eight flavors such as all the other Olibanums are ground into fine powder, with above-mentioned powder facing-up, sieve, and mixing promptly.The powder onset is rapid, but takes inconvenience, and divided dose is inaccurate, and its quality standard still can further improve, and this pharmaceutically dosage form is single simultaneously, and application forms still has only powder, can't satisfy people's medication demand.Based on this, we use modern pharmaceutical technology and detection means this product technology are done necessary improvement, thereby and the quality of product is carried out overall monitor guarantee that product quality benefits the common people.
Summary of the invention
The purpose of this invention is to provide a kind of Flos Carthami notoginseng-containing tablet and preparation method, improve the quality of products, enrich medicine variety, satisfy needs of medical treatment better.
The objective of the invention is such realization:
1, Flos Carthami notoginseng-containing tablet and preparation method comprise the steps:
1.1 the prescription of Flos Carthami notoginseng-containing tablet is formed:
Olibanum (processed with vinegar) 10-40g Flos Carthami 10-40g Sanguis Draxonis 30-110g Moschus 0.2-1.0g
Radix Angelicae Sinensis (wine is processed) 1-6g catechu 18-65g Cinnabaris 10-40g Lignum Dalbergiae Odoriferae 60-210g
Radix Notoginseng 60-210g Myrrha (processed with vinegar) 10-40g Borneolum Syntheticum 1-3g
Right amount of auxiliary materials is made 1000 altogether
Its optimum formula is:
Olibanum (processed with vinegar) 26.1g Flos Carthami 26.1g Sanguis Draxonis 69.55g Moschus 0.55g
Radix Angelicae Sinensis (wine is processed) 3.5g catechu 41.75g Cinnabaris 26.1g Lignum Dalbergiae Odoriferae 139.15g
Radix Notoginseng 139.15g Myrrha (processed with vinegar) 26.1g Borneolum Syntheticum 2.1g
Right amount of auxiliary materials is made 1000 altogether
1.2 Flos Carthami notoginseng-containing tablet preparation technology
In will writing out a prescription ten simply medical material be up to the standards standby respectively; Cinnabaris is ground into impalpable powder; Moschus, Borneolum Syntheticum are ground into fine powder respectively; Eight flavors such as all the other Olibanums are ground into fine powder, with above-mentioned Cinnabar mixing, granulate, and drying adds Moschus, Borneolum Syntheticum fine powder and right amount of auxiliary materials, and mixing, tabletting, promptly.
1.3 prepared by technology is tablet.
The gained tablet can wrap film-coat in the technology, and its Film coated tablets material can adopt stomach dissolution type film-coat pre-mixing agent (Opadry).
Adjuvant used in the technology is: any or multiple mixing in microcrystalline Cellulose, polyvinylpolypyrrolidone, carboxymethylstach sodium, 30 POVIDONE K 30 BP/USP 30, micropowder silica gel, low-substituted hydroxypropyl cellulose, starch, dextrin, the magnesium stearate etc. is used.
The technology Chinese crude drug is ground into fine powder and was generally 80-160 order fine powder, and being preferably superfine powder, to be broken into 200-300 order fine powder standby.
Cinnabaris is ground into impalpable powder and can adopts elutriation or micronizing method in the technology.
The dry boulton process that adopts in the technology, temperature is controlled at 50-80 ℃ and is preferably 60 ℃.
2, the quality control standard of Flos Carthami notoginseng-containing tablet further improves on former powder basis among the present invention, former dosage form has been carried out the thin layer discriminating to Radix Notoginseng, Radix Angelicae Sinensis on differentiating, now kept, and increased the thin layer of catechu, Olibanum, Myrrha has been differentiated, on assay, former dosage form has carried out quantitatively now being kept to Sanguis Draxonis, and increased to Radix Notoginseng quantitatively.
This invention with have form improvement on the basis of powder now, it is inaccurate to have overcome former powder divided dose, takes the deficiency of inconvenience, quality standard has new raising again, be of great importance to improving the quality of products, enriched medicine variety, satisfy and ensured people's medication demand.
The specific embodiment
Optimum implementation of the present invention is: in will writing out a prescription ten simply medical material be up to the standards standby respectively; Cinnabaris is ground into impalpable powder; Moschus, Borneolum Syntheticum are ground into fine powder respectively; Eight flavors such as all the other Olibanums are ground into fine powder, with above-mentioned Cinnabar mixing, granulate, and drying adds Moschus, Borneolum Syntheticum fine powder and right amount of auxiliary materials, and mixing, tabletting, promptly.
Claims (7)
1, a kind of Flos Carthami notoginseng-containing tablet and preparation method is characterized in that: in will writing out a prescription ten simply medical material be up to the standards standby respectively; Cinnabaris is ground into impalpable powder; Moschus, Borneolum Syntheticum are ground into fine powder respectively; All the other Olibanums, Flos Carthami, Sanguis Draxonis, Radix Angelicae Sinensis, catechu, Lignum Dalbergiae Odoriferae, Radix Notoginseng, Myrrha eight flavors are ground into fine powder, with above-mentioned Cinnabar mixing, granulate, and drying adds Moschus, Borneolum Syntheticum fine powder and right amount of auxiliary materials, and mixing, tabletting makes the Flos Carthami notoginseng-containing tablet.
2, Flos Carthami notoginseng-containing tablet according to claim 1 and preparation method, it is characterized in that: the gained tablet can wrap film-coat in the technology, and its Film coated tablets material can adopt stomach dissolution type film-coat pre-mixing agent Opadry.
3, Flos Carthami notoginseng-containing tablet according to claim 1 and preparation method is characterized in that: adjuvant used in the technology is: any/multiple mixing in microcrystalline Cellulose, polyvinylpolypyrrolidone, carboxymethylstach sodium, 30 POVIDONE K 30 BP/USP 30, micropowder silica gel, low-substituted hydroxypropyl cellulose, starch, dextrin, the magnesium stearate etc. is used.
4, Flos Carthami notoginseng-containing tablet according to claim 1 and preparation method is characterized in that: the technology Chinese crude drug is ground into fine powder and was generally 80-160 order fine powder, and being preferably superfine powder, to be broken into 200-300 order fine powder standby.
5, Flos Carthami notoginseng-containing tablet according to claim 1 and preparation method is characterized in that: Cinnabaris is ground into impalpable powder and can adopts elutriation/micronizing method in the technology.
6, Flos Carthami notoginseng-containing tablet according to claim 1 and preparation method is characterized in that: the dry boulton process that adopts in the technology, temperature is controlled at 50-80 ℃ and is preferably 60 ℃.
7, Flos Carthami notoginseng-containing tablet according to claim 1 and preparation method is characterized in that: have the thin layer of catechu, Olibanum, Myrrha to differentiate that the detection by quantitative of Radix Notoginseng is arranged on quality inspection standard.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031182860A CN1537580A (en) | 2003-04-15 | 2003-04-15 | Honghua Qili tablet contg. safflower carthamus, and its prepn. method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031182860A CN1537580A (en) | 2003-04-15 | 2003-04-15 | Honghua Qili tablet contg. safflower carthamus, and its prepn. method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1537580A true CN1537580A (en) | 2004-10-20 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA031182860A Pending CN1537580A (en) | 2003-04-15 | 2003-04-15 | Honghua Qili tablet contg. safflower carthamus, and its prepn. method |
Country Status (1)
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| CN (1) | CN1537580A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100387277C (en) * | 2006-01-23 | 2008-05-14 | 重庆希尔安药业有限公司 | Preparation method of notoginseng-containing tablet for treating traumatic injury |
| CN101732424B (en) * | 2010-01-20 | 2011-05-25 | 侯云祥 | Chinese medicinal powder for treating pharyngitis |
| CN104007187A (en) * | 2013-02-27 | 2014-08-27 | 湖南天地恒一制药有限公司 | Detection method for safflower-qili capsule |
| CN104000980A (en) * | 2013-02-27 | 2014-08-27 | 湖南天地恒一制药有限公司 | Traditional Chinese medicine preparation for treating traumatic injury, and preparation method thereof |
| CN112386647A (en) * | 2019-08-15 | 2021-02-23 | 秦小学 | Baiyu ointment and its preparing and using method |
-
2003
- 2003-04-15 CN CNA031182860A patent/CN1537580A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100387277C (en) * | 2006-01-23 | 2008-05-14 | 重庆希尔安药业有限公司 | Preparation method of notoginseng-containing tablet for treating traumatic injury |
| CN101732424B (en) * | 2010-01-20 | 2011-05-25 | 侯云祥 | Chinese medicinal powder for treating pharyngitis |
| CN104007187A (en) * | 2013-02-27 | 2014-08-27 | 湖南天地恒一制药有限公司 | Detection method for safflower-qili capsule |
| CN104000980A (en) * | 2013-02-27 | 2014-08-27 | 湖南天地恒一制药有限公司 | Traditional Chinese medicine preparation for treating traumatic injury, and preparation method thereof |
| CN112386647A (en) * | 2019-08-15 | 2021-02-23 | 秦小学 | Baiyu ointment and its preparing and using method |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |