CN1528367A - Chinese medicine composition for treating cardio-cerebrovascular diseases - Google Patents
Chinese medicine composition for treating cardio-cerebrovascular diseases Download PDFInfo
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Abstract
The present invention relates to a Chinese medicine composition with the functions of improving cardio-cerebral blood circulation, effectively reducing blood fat and platelet aggregation rate, reducing blood viscosity, smoothly and stably reducing blood pressure for curing angiocardiopathy and cerebo-vascular disease with obvious therapeutic effect free from side effect. Said Chinese medicine composition includes 20 Chinese medicinal materials of trichosanthes fruit, pinellia tuber, coptis root, prunella spike, leech, earthworm and others.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine composition for the treatment of cardiovascular and cerebrovascular disease.
Background technology
Cardiovascular and cerebrovascular disease is current harm humans life and healthy commonly encountered diseases, is that middle age causes death, major cause of morbidity.Along with increasing rapidly of China's aging population, cardiovascular and cerebrovascular disease is ascendant trend year by year.At present at first of the row of putting in order of China's various diseases cause of the death.Coronary heart disease accounts for more than 10% in northern human mortality, and the whole nation is died from more than about 1,000,000 people of patient of apoplexy every year.Therefore be our medical matters circle task of top priority to the control of cardiovascular and cerebrovascular disease and research.
Technology contents
The object of the present invention is to provide a kind of Chinese medicine composition that the treatment cardiovascular and cerebrovascular disease is had remarkable result.
The present invention is achieved through the following technical solutions:
Choose crude drug
Fructus Trichosanthis 10-50 weight portion Rhizoma Pinelliae 12-40 weight portion Spica Prunellae 10-50 weight portion
Rhizoma Coptidis 12-40 weight portion Hirudo 25-80 weight portion Pheretima 20-80 weight portion
Tabanus 25-80 weight portion eupolyphage sece steleophaga 25-80 weight portion Rhizoma Gastrodiae 10-50 weight portion
Ramulus Uncariae Cum Uncis 10-50 weight portion Rhizoma Acori Graminei 12-40 weight portion Radix Polygalae 12-40 weight portion
Radix Salviae Miltiorrhizae 10-50 weight portion Rhizoma Chuanxiong 12-40 weight portion Lignum Dalbergiae Odoriferae 5-20 weight portion
Stigma Croci 5-20 weight portion Styrax 12-40 weight portion Herba Apocyni veneti 10-50 weight portion
Cortex Eucommiae 12-40 weight portion Cornu Saigae Tataricae 12-40 weight portion Bulbus Fritillariae Thunbergii 12-40 weight portion
Radix Notoginseng 12-40 weight portion
Optimum ratio of the present invention is:
The Fructus Trichosanthis 30 weight portion Rhizoma Pinelliaes 20 weight portion Spica Prunellaes 30 weight portions
Rhizoma Coptidis 20 weight portion Hirudos 50 weight portion Pheretimas 50 weight portions
Tabanus 50 weight portion eupolyphage sece steleophagas 50 weight portion Rhizoma Gastrodiaes 30 weight portions
Ramulus Uncariae Cum Uncis 30 weight portion Rhizoma Acori Gramineis 20 weight portion Radix Polygalaes 20 weight portions
Radix Salviae Miltiorrhizae 30 weight portion Rhizoma Chuanxiongs 20 weight portion Lignum Dalbergiae Odoriferaes 10 weight portions
Stigma Croci 10 weight portion Styrax 20 weight portion Herba Apocyni venetis 30 weight portions
The Cortex Eucommiae 20 weight portion Cornu Saigae Tataricae 20 weight portions
Preparation method of the present invention is a pulverizing at ultralow temperature, and operating temperature is 20-40 ℃, the crude drug micronizing, and medicated powder is crossed 300 mesh sieve micropowders, 400-600 nanometer, and the reuse traditional handicraft is made pill.
Press practice of pharmacy, compositions of the present invention can be added adjuvant and be prepared into the various clinical pharmaceutical dosage form, comprise any in tablet, capsule, pill, suspensoid, drop pill, the oral liquid.
Described adjuvant is meant conventional excipient, as solvent, disintegrating agent, correctives, antiseptic, coloring agent, binding agent etc.
Heart and brain of the present invention are safe to be compared with other similar drug, has following several big characteristics:
1, heart and brain are ruled together: select different medicines for use at the medicine rake point that heart and brain two internal organs are different, make drug effect more accurate, make medicine in heart and brain onset simultaneously.
2, etiology and pathogenesis treatment: heart and brain are safe not only to improve the heart and brain blood circulation by blood circulation promoting and blood stasis dispelling, also blood fat reducing PAR, blood viscosity lowering effectively, and can steadily bring high blood pressure down.
3, powerful anticoagulant and thrombolytic effect is arranged, dissolve thrombosis and eliminate the thrombosis factor, microcirculation improvement promotes edema and hemorrhage absorption, strong upright side Zhi Xunhuan.
4, the protection blood vessel endothelium is dispeled hardened fat stricture of vagina and speckle.Recover the blood vessel wall epistasis, remove cardiovascular and cerebrovascular disease initiation potential factor, protecting myocardial cell and cranial nerve cell.
5, preparation technology advanced person: adopt nanotechnology, make medicine reach 500 nanometers, pulverizing at ultralow temperature (＜40 ℃), medicament active composition is without prejudice, and makes drug effect improve 5-7 doubly.
Following experimental example is used to further specify the present invention.
Heart and brain of the present invention are safe since in 1998 applying clinical, are used for the treatment of cardiovascular and cerebrovascular disease and obtained satisfied curative effect, now are reported as follows:
1, clinical data
140 routine patients are outpatient service and inpatient, meet WHO " name of ischemic heart desease and diagnostic criteria ", and the traditional Chinese medical science is with reference to " tcm clinical practice disease diagnosis criterion of therapeutical effect ", the diagnostic criteria of national cardiovascular and cerebrovascular disease academic conference revision in 1996.Male's 86 examples wherein, women's 54 examples, age 45-76 year, average 56.3 ± 9.1 years old.Course of disease 1-2, average 8.3 years, by being divided into observation group's 80 examples at random, matched group 60 examples, two groups clinical has comparability (P＜0.05) and annotates: (observation group-treatment group)
2, treatment and observational technique:
2.1 GP TH: it is safe that oral heart and brain of the present invention are organized in treatment, every day 3 times, each 5g.The oral five happinesses XINNAOKANG of matched group, every day 3 times, each 3g, two groups was a course of treatment with 30 days all.
2.2 observational technique: treated preceding 1 day and treated the back and check related item, comprise clinical symptoms, sign, routine electrocardiogram, hemorheology is learned, cerebrovascular blood dynamics analysis etc.
3, therapeutic effect:
3.1 comprehensive therapeutic effect standard: produce effects: cardiopalmus and angina pectoris, cardinal symptoms such as dizziness headache disappear, and it is normal that electrocardiogram recovers, and rheoencephalogram is normal.Effectively: the angina pectoris degree alleviates, and dizziness headache alleviates, and electrocardiogram, rheoencephalogram improve, and invalid: symptom: electrocardiogram, rheoencephalogram etc. does not all have the changer.
3.2 two groups of comprehensive therapeutic effects relatively: 80 examples are organized in treatment, produce effects 30 examples (37.5%), effective 46 examples (55%), invalid 4 examples (7.5%), total effective rate (92.5%), matched group 60 examples, effective 23 examples of produce effects 14 examples (23.3%) (38.33%), invalid 23 examples (38.33), total effective rate are that 61.67%, two group of comparing difference has significance (P＜0.05).Present composition preparation effect is better than matched group.
3.3 two groups of other indexs are improved relatively: it is 93.75% that treatment group cardiopalmus, chest pain are improved total effective rate, matched group is 63.33%, comparing difference has significance (P＜0.05) treatment group dizziness between group, to improve total effective rate be 88.8% in headache, matched group is 56.2%, and comparing difference has significance (P＜0.05) between group.It is 73.75% that treatment group electrocardiogram, rheoencephalogram improve total effective rate, and matched group is 43.32%, and comparing difference has significance (P＜0.05) between group.Present composition preparation effect is better than matched group.
4, discuss:
Cardiovascular and cerebrovascular disease comprises hypertension, coronary heart disease, brain A sclerosis, cerebral infarction, cerebral hemorrhage etc., and it is dizzy to be under the jurisdiction of the traditional Chinese medical science, thoracic obstruction category.Qi depression to blood stasis, the mutual resistance of the expectorant stasis of blood is its pathologic basis.Meaning according to " interior warp " " promoting circulation of QI-blood; make it reach ", the safe upright removing blood stasis of heart and brain is a rule of treatment, is aided with removing heat-phlegm, suppressing the hyperactive liver to relieve the wind syndrome, be monarch with Hirudo, Pheretima, Tabanus in the side, Zhang Xichun calls Hirudo " removing blood stasis is not just being hindered, and blood stasis dispelling blood is in right quietly ", the salty raw meat of Hirudo abnormal smells from the patient, through blood system, the kind broken hard stasis of blood.The horsefly trematodiasis has flown to extort the power of stagnant blood, and Pheretima is born in kind the meridian dredging in the soil, and three medicines are harmonious, and blood stasis goes to the greatest extent, and passages through which vital energy circulates is unimpeded.Minister is with full pawl beach wormwood, Rhizoma Coptidis, the Rhizoma Pinelliae, Rhizoma Arisaematis (processed), Rhizoma Acori Graminei, Calculus Bovis, clearing and dissipating phlegm-heat.Help with Spica Prunellae Herba Apocyni veneti, Bombyx Batryticatus, Cornu Saigae Tataricae suppressing the hyperactive liver to relieve the wind syndrome.Make with Styrax, Moschus, Radix Notoginseng, Stigma Croci, Borneolum Syntheticum help the capable arteries and veins of blood, the pain relieving of reducing phlegm.If the safe choosing side of heart and brain is classical, and the compatibility compactness is scientific and reasonable, is used for clinically, imitates the small wooden raft fermented soya beans, salted or other wise.
Modern medicine thinks that the pathologic basis of cardiovascular and cerebrovascular disease is an atherosclerosis, the tunica intima damage, and luminal stenosis, blood flow is obstructed.The modern pharmacological research Hirudo contains hirudin, and powerful anticoagulation is arranged.Pheretima contains Lumbrukinase, and thrombolytic effect is preferably arranged, and can remove the intra-arterial speckle, repairs tunica intima.Full pawl withers, Rhizoma Coptidis, Rhizoma Arisaematis (processed), and Spica Prunellae etc. are blood fat reducing effectively, and PAR improves hemorheological property, regulates lipid metabolism, reaches the purpose of blood fat-reducing blood pressure-decreasing, and the formation of change atherosclerosis plaque block organization has the effect that alleviates with stabilize plaque.Blood vessel endothelium is repaired in protection, improves the heart and brain blood flow rate, increases the heart and brain blood flow, microcirculation improvement, and reach the functional rehabilitation of heart and brain tissues.
Model case
Case 1:
Name: the king * * birthplace: Yutian County, Hebei province
Sex: male permanent address: No. 8, nine station, Road Inside Area, Harbin City street
Age: 58 years old unit: Heilongjiang Province's sports committee
National: Chinese admission time: on JIUYUE 18th, 1999
The wedding condition: history-taking time: on JIUYUE 18th, 1999
Occupation: workman's medical history representor: I
Morbidity solar term: the beginning of autumn
The main suit: feeling of oppression and pain in the chest, dizzy feeling of fullness in the head, the limb fiber crops are surplus February.
History of present illness: the vertigo occurred before 2 years, a property crossed is fainted face hectic fever, tinnitus.Gradually to feeling of oppression and pain in the chest, cardiopalmus is nervous, the feeling of fullness in the head headache, the 5th hospital of seeking medical advice in the Harbin, BP:170-100mmHg, be diagnosed as " hypertension " " coronary heart disease " once be interrupted take hypertension pill, the storax pill for treating coronary heart disease controlling of blood pressure is undesirable.
History of past illness: previously healthy, free from infection history, nothing operation trauma history.
Personal history: be engaged in sports, living environment is good always, and habits of smoking and alcohol drinking are arranged.
Allergies: no food, drug allergy history.
Family history: no family genetic diseases history.
Physical examination:
36.2 ℃ of body temperature (T), pulse (P) 92 times/minute, breathe (R) 18 times/minute, blood pressure (BP) 180-105mmHg, step into ward, hemiplegic gait, speech is unsmooth, purple falls in purple dim, the Blushing of lip, tongue, what speckle, yellow and greasy fur, wiry and frequent pulse, skin do not have xanthochromia, lymph node does not have enlargement.Trachea is placed in the middle, neck A, V do not have angry, thorax symmetry, and respiratory murmur is clear.Apex beat is extensive, in the 5th, six intercostal spaces, trembles, stethoscope heart sound is hyperfunction, and abdominal part is smooth, and palpation liver, spleen are no abnormal, spinal column does not have bending, and activity still can.
Neural reflex: left side Hoffmann levies (+) Babinski and levies (+)
Left side muscular strength II level, right side muscular strength are normal.
Training is checked: CT shows: right side capsula interna district lacunar infarction.
Electrocardio diagram ST section is forced down, the T ripple is inverted, left chamber high voltage.
Laboratory: T-CHOL: 8.75mmoL/L, triglyceride: 3.65mmOL/L AD:
Tcm diagnosis: the apoplexy-apoplex involving the channels and collaterals thoracic obstruction,
Western medicine diagnose: coronary heart disease, hypertension, cerebral lacunae infraction, hyperlipemia treatment; Obey safe 3g/ time of heart and brain of the present invention, three early, middle and late sub-services every day.
On JIUYUE 24th, 1999, with one week of medicine of the present invention, various symptom all alleviate, blood pressure BP:140-90mmHg, P:82 time/minute, electrocardio diagram: low flat, the T-CHOL 6.75mmoL/L of ST section equipotential line, 7 ripples, sweet three fat 2.5mmL/L left limbs, the numb alleviation, it is normal that the left limb Myodynamia recovery is followed up a case by regular visits in continue to take heart and brain of the present invention safe three months, later stage, continued to participate in the worker
Case 2:
Name: open * * birthplace: the Jinan City, Shandong Province
Sex: women permanent address: No. 78, Nangang District great achievement street, Harbin City
Age: 61 years old unit: the 125th middle school, Harbin City
National: Chinese admission time: on December 26th, 2000
The wedding condition: history-taking time: on December 26th, 2000
Occupation: teacher's medical history representor: I
The main suit: chest pain radiating to the back, lose heart, pant, feeling of fullness in the head headache one month.
History of present illness: nervous, the sensation of oppression over the chest with shortness of breath of cardiopalmus before 5 years, gradually to chest pain, disappeared in 2-3 minute, province university of TCM is diagnosed as hypertension, coronary heart disease, BP:150-95mmHg, treat to storax pill for treating coronary heart disease, alleviated, chest pain increases the weight of closely over the past half year, every day three, five times, alleviated in 7,8 minutes sometimes, simultaneously the companioned with headache feeling of fullness in the head.
History of past illness: previously healthy, free from infection history, local medical history do not have the operation trauma history.
Personal history: be engaged in teaching job, living environment is better always, no tobacco and wine hobby.
Allergies: no food, drug allergy history.
Family history: its grandfather once suffered from hypertension, died from myocardial infarction.
Physical examination: body temperature (T): 36.5 ℃, pulse (P): 86 times/minute, breathing (R): 17 times/minute, blood pressure (BP) 160-100mmhg.
Integral status: the patient steps into that ward, refreshing clear language are sharp, red red, the lip of face purple dim, body of the tongue is livid purple, what speckle what point, pulse string are hard.Skin does not have xanthochromia, lymph node does not have enlargement.Trachea is placed in the middle, neck A do not have angryly open, thorax symmetry, respiratory murmur be clear.Apex beat in the 5th intercostal space, atremia, stethoscope heart sound be hyperfunction.Abdominal part is smooth, palpation liver spleen is no abnormal.Spinal column does not have bending, activity freely.Neural reflex (one) palm jaw reflex (+).
Training is checked: electrocardio diagram: ST-T change, coronary T wave, abnormality Q wave.
Laboratory: T-CHOL 8.95mmoL/L, triglyceride 3.75mmoL/L.
AD: tcm diagnosis: the thoracic obstruction, dizzy
Western medicine diagnose: coronary heart disease, unstable angina pectoris, hypertension.
Treatment: obey safe 5g/ time of heart and brain of the present invention, every day three early, middle and late taking.
On January 6th, 2003, clothes medicine of the present invention after 1 week, feeling of oppression and pain in the chest disappearances, blood pressure 135-85mmHg, P:78 time/minute, electrocardio diagram: ST section equipotential line, T ripple be low puts down, leave hospital continue safe two months of heart and brain of clothes, blood pressure, electrocardiogram recovery normally, blood fat is normal.
Embodiment 1
Fructus Trichosanthis 30g Rhizoma Pinelliae 20g Spica Prunellae 30g Rhizoma Coptidis 20g
Hirudo 50g Pheretima 50g Tabanus 50g eupolyphage sece steleophaga 50g
Rhizoma Gastrodiae 30g Ramulus Uncariae Cum Uncis 30g Rhizoma Acori Graminei 20g Radix Polygalae 20g
Radix Salviae Miltiorrhizae 30g Rhizoma Chuanxiong 20g Lignum Dalbergiae Odoriferae 10g Stigma Croci 10g
Styrax 20g Herba Apocyni veneti 30g Cortex Eucommiae 20g Cornu Saigae Tataricae 20g
Bulbus Fritillariae Thunbergii 20g Radix Notoginseng 20g
With above-mentioned pulverizing at ultralow temperature, 30 ℃ of operating temperatures, micronizing, medicated powder is crossed 300 mesh sieve micropowders, 500 nanometers, makes pill traditionally.Each clothes 3g, every day three times.
Embodiment 2
Fructus Trichosanthis 20g Rhizoma Pinelliae 30g Spica Prunellae 25g Rhizoma Coptidis 25g
Hirudo 40g Pheretima 50g Tabanus 50g eupolyphage sece steleophaga 50g
Rhizoma Gastrodiae 40g Ramulus Uncariae Cum Uncis 35g Rhizoma Acori Graminei 15g Radix Polygalae 20g
Radix Salviae Miltiorrhizae 25g Rhizoma Chuanxiong 15g Lignum Dalbergiae Odoriferae 10g Stigma Croci 10g
Styrax 15g Herba Apocyni veneti 35g Cortex Eucommiae 15g Cornu Saigae Tataricae 25g
Bulbus Fritillariae Thunbergii 15g Radix Notoginseng 25g
Said medicine technology is routinely made capsule.
Claims (4)
1, a kind of Chinese medicine composition for the treatment of cardiovascular and cerebrovascular disease is characterized in that said composition mainly made by following crude drug:
Fructus Trichosanthis 10-50 weight portion Rhizoma Pinelliae 12-40 weight portion Spica Prunellae 10-50 weight portion
Rhizoma Coptidis 12-40 weight portion Hirudo 25-80 weight portion Pheretima 20-80 weight portion
Tabanus 25-80 weight portion eupolyphage sece steleophaga 25-80 weight portion Rhizoma Gastrodiae 10-50 weight portion
Ramulus Uncariae Cum Uncis 10-50 weight portion Rhizoma Acori Graminei 12-40 weight portion Radix Polygalae 12-40 weight portion
Radix Salviae Miltiorrhizae 10-50 weight portion Rhizoma Chuanxiong 12-40 weight portion Lignum Dalbergiae Odoriferae 5-20 weight portion
Stigma Croci 5-20 weight portion Styrax 12-40 weight portion Herba Apocyni veneti 10-50 weight portion
Cortex Eucommiae 12-40 weight portion Cornu Saigae Tataricae 12-40 weight portion Bulbus Fritillariae Thunbergii 12-40 weight portion
Radix Notoginseng 12-40 weight portion.
2, Chinese medicine composition according to claim 1 is characterized in that said composition mainly made by following crude drug:
The Fructus Trichosanthis 30 weight portion Rhizoma Pinelliaes 20 weight portion Spica Prunellaes 30 weight portions
Rhizoma Coptidis 20 weight portion Hirudos 50 weight portion Pheretimas 50 weight portions
Tabanus 50 weight portion eupolyphage sece steleophagas 50 weight portion Rhizoma Gastrodiaes 30 weight portions
Ramulus Uncariae Cum Uncis 30 weight portion Rhizoma Acori Gramineis 20 weight portion Radix Polygalaes 20 weight portions
Radix Salviae Miltiorrhizae 30 weight portion Rhizoma Chuanxiongs 20 weight portion Lignum Dalbergiae Odoriferaes 10 weight portions
Stigma Croci 10 weight portion Styrax 20 weight portion Herba Apocyni venetis 30 weight portions
The Cortex Eucommiae 20 weight portion Cornu Saigae Tataricae 20 weight portions.
3, Chinese medicine composition according to claim 1 and 2 is characterized in that said composition can be prepared into the various clinical pharmaceutical dosage form, any as in tablet, capsule, granule, pill, suspensoid, drop pill, the oral liquid.
4, the preparation method of Chinese medicine composition pharmaceutical dosage form according to claim 4 is characterized in that, crude drug is pulverizing at ultralow temperature at first, and operating temperature is 20-40 ℃, the crude drug micronizing, and medicated powder is crossed 300 mesh sieve micropowders, 400-600 nanometer.
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| CNA031347134A CN1528367A (en) | 2003-09-29 | 2003-09-29 | Chinese medicine composition for treating cardio-cerebrovascular diseases |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1907386B (en) * | 2006-08-20 | 2010-05-12 | 张掖市药品检验所 | Chinese traditional medicinal composition for treating hyperlipemia, hypertension, and coronary disease |
| CN101099828B (en) * | 2007-06-27 | 2010-05-19 | 陕西盘龙制药集团有限公司 | Soft capsule for reducing blood pressure and improving sleeping |
| CN101161253B (en) * | 2006-10-12 | 2010-12-15 | 山东轩竹医药科技有限公司 | Pharmaceutical composition of melon betel or its extract and safflower or its extract |
| CN101361855B (en) * | 2008-09-28 | 2011-08-17 | 田桂保 | Medicine for reducing and stabilizing blood-pressure |
| CN102302681A (en) * | 2011-08-10 | 2012-01-04 | 天津宏仁堂药业有限公司 | Medicinal composition for treating cerebral infarction |
| CN102000315B (en) * | 2007-10-31 | 2012-06-13 | 北京亚东生物制药有限公司 | Traditional Chinese medicinal composition for treating dizziness and preparation method thereof |
| CN102727575A (en) * | 2012-07-06 | 2012-10-17 | 李长奎 | Medicine for treating hypertension, hyperlipidemia and hyperglycemia and preparation method of medicine |
| CN103948751A (en) * | 2014-05-13 | 2014-07-30 | 陈文才 | Traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases and application method thereof |
| CN108066627A (en) * | 2018-02-02 | 2018-05-25 | 重庆跃龙生物制药有限公司 | For treating Chinese medicine composition of cerebral thrombus and/or cerebral hemorrhage and preparation method thereof |
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2003
- 2003-09-29 CN CNA031347134A patent/CN1528367A/en active Pending
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1907386B (en) * | 2006-08-20 | 2010-05-12 | 张掖市药品检验所 | Chinese traditional medicinal composition for treating hyperlipemia, hypertension, and coronary disease |
| CN101161253B (en) * | 2006-10-12 | 2010-12-15 | 山东轩竹医药科技有限公司 | Pharmaceutical composition of melon betel or its extract and safflower or its extract |
| CN101099828B (en) * | 2007-06-27 | 2010-05-19 | 陕西盘龙制药集团有限公司 | Soft capsule for reducing blood pressure and improving sleeping |
| CN102000315B (en) * | 2007-10-31 | 2012-06-13 | 北京亚东生物制药有限公司 | Traditional Chinese medicinal composition for treating dizziness and preparation method thereof |
| CN101361855B (en) * | 2008-09-28 | 2011-08-17 | 田桂保 | Medicine for reducing and stabilizing blood-pressure |
| CN102302681A (en) * | 2011-08-10 | 2012-01-04 | 天津宏仁堂药业有限公司 | Medicinal composition for treating cerebral infarction |
| CN102302681B (en) * | 2011-08-10 | 2013-08-14 | 天津宏仁堂药业有限公司 | Medicinal composition for treating cerebral infarction |
| CN102727575A (en) * | 2012-07-06 | 2012-10-17 | 李长奎 | Medicine for treating hypertension, hyperlipidemia and hyperglycemia and preparation method of medicine |
| CN102727575B (en) * | 2012-07-06 | 2015-04-01 | 李长奎 | Medicine for treating hypertension, hyperlipidemia and hyperglycemia and preparation method of medicine |
| CN103948751A (en) * | 2014-05-13 | 2014-07-30 | 陈文才 | Traditional Chinese medicine for preventing and treating cardiovascular and cerebrovascular diseases and application method thereof |
| CN103948751B (en) * | 2014-05-13 | 2018-01-02 | 陈文才 | For preventing and treating the Chinese medicine and its application process of cardiovascular and cerebrovascular disease |
| CN108066627A (en) * | 2018-02-02 | 2018-05-25 | 重庆跃龙生物制药有限公司 | For treating Chinese medicine composition of cerebral thrombus and/or cerebral hemorrhage and preparation method thereof |
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