CN1526431A - Chinese medicine for treating osteological diseases and its prepn process - Google Patents
Chinese medicine for treating osteological diseases and its prepn process Download PDFInfo
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- CN1526431A CN1526431A CNA031326323A CN03132632A CN1526431A CN 1526431 A CN1526431 A CN 1526431A CN A031326323 A CNA031326323 A CN A031326323A CN 03132632 A CN03132632 A CN 03132632A CN 1526431 A CN1526431 A CN 1526431A
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Abstract
The present invention relates to one kind of Chinese medicine for treating osteological diseases and its preparation process. The Chinese medicine is prepared with pilose antler, epimedium, desert cistanche, eucommia bark and prepared rhizome of rehmannia. It has the functions of invigorating kidney, invigorating Yang, promoting blood circulation, relieving pain, and dispelling wind-evil and wetness-evil. It can improve the microcirculation of body tissue, increase blood flow rate of body tissue, regulate organic substance, calcium and phosphorus metabolism, increase the nutrients provided to bone joints, raise the metabolic activity of bone cell, raise the wear resistance and shock resistance of joint and soft tissue. It is used in treating osteological diseases, and has high effective rate and curative rate and no toxic side effect.
Description
Affiliated field: the present invention relates to a kind of Chinese medicine for the treatment of orthopaedic disease and preparation method thereof.
Background technology: orthopaedic disease is a kind of persistent ailment of serious harm human health, and it comprises the described femur head necrosis of modern medicine, prolapse of lumbar intervertebral disc, rheumatism, rheumatoid, osteoarthritis, cervical spondylosis, scapulohumeral periarthritis, Kaschin-Beck disease etc.Above-mentioned various diseases seriously develops, and except that the treatment that operates, still lacks the most effectively medicine.
Summary of the invention: the objective of the invention is to carry a kind of Chinese medicine for the treatment of orthopaedic disease, it all has stable curative effect to femur head necrosis, prolapse of lumbar intervertebral disc, rheumatism, rheumatoid, osteoarthritis, treating both the principal and secondary aspects of a disease, and have no side effect.
The present invention also aims to provide a kind of preparation method for the treatment of orthopaedic disease, its medicinal material extract rate height, the bioavailability height, and can guarantee the stable performance of curative effect of medication preferably.
The objective of the invention is to realize in the following manner: the present invention is a kind of Chinese medicine for the treatment of orthopaedic disease, and the prescription of this medicine and proportioning are: Herba Epimedii 50-80 gram, Radix Gentianae Macrophyllae 60-80 gram, Herba Pyrolae 50-80 gram, Radix Notoginseng 50-80 gram, Radix Rehmanniae Preparata 80-100 gram, Radix Angelicae Pubescentis 50-80 gram, Rhizoma Drynariae 50-100 gram, Herba Cistanches 50-80 gram, Cortex Eucommiae 80-100 gram, Olibanum 80-100 gram, Myrrha 80-100 gram, Caulis Spatholobi 80-100 gram, Cornu Cervi Pantotrichum 10-20 gram, Pheretima 80-100 gram.
Preparation method of the present invention is: A: get the raw materials ready according to following prescription and proportioning: the prescription of this medicine and proportioning are: Herba Epimedii 50-80 gram, Radix Gentianae Macrophyllae 60-80 gram, Herba Pyrolae 50-80 gram, Radix Notoginseng 50-80 gram, Radix Rehmanniae Preparata 80-100 gram, Radix Angelicae Pubescentis 50-80 gram, Rhizoma Drynariae 50-100 gram, Herba Cistanches 50-80 gram, Cortex Eucommiae 80-100 gram, Olibanum 80-100 gram, Myrrha 80-100 gram, Caulis Spatholobi 80-100 gram, Cornu Cervi Pantotrichum 10-20 gram, Pheretima 80-100 gram.It is standby that Radix Notoginseng, Cornu Cervi Pantotrichum are ground into segmentation, mixes after all the other 12 flavor medicine washings and mix thoroughly, and the water of 10 times of amounts of adding decocted 2.5 hours;
B: after obtaining filtrate, in the medical material of decoction liquor, add the water of 5 times of amounts again, decocted 1.5 hours;
C: secondary decocts filtrate merging, and concentrated filtrate to relative density is 1.10-1.15, and measuring temperature is the extractum that 80 degree heat are surveyed, and puts cold;
D: in extractum, slowly add concentration and be 95% ethanol, make to contain the alcohol amount and reach 60, fully stir, left standstill 24 hours;
E: filter, reclaim ethanol, concentrated medicament to relative density is 1.35-1.40, and measuring temperature is the extractum that 80 degree heat are surveyed;
F: behind extract dry, add the former powder of Radix Notoginseng, Cornu Cervi Pantotrichum prepare again, abundant mixing is pulverized, is sieved, encapsulated.
Motherland's theory of medicine is thought: how the etiology and pathogenesis of orthopaedic disease is endogenous cause of ill with plain body yang-energy, cloudy insufficiency of essence, and the heresy that wind and cold is damp and hot is an exopathogenic factor, from the beginning of based on the domination of pathogen, sick position is at the limbs meridians, and prolonged illness is then more belongs to weakened body resistance evilness, or simulataneous insufficiency and excessive, sick position is then deeply at muscles and bones or internal organs, and internal organs void declines, positive QI-insufficiency, the failure of defensive QI to protect the body against pathogen exopathogen is easily invaded, so the osteoarthrosis degeneration, pathogen is controlled for a long time, the QI and blood cervical carcinoma with cachexia, so joint stuffiness, the myoatrophy distortion.Kidney governing bones bone growth promoting water, liver blood master muscle, it is foster to can not get moistening of essence and blood as muscles and bones, gradually degradation degeneration, finally cause the osteoarthrosis degeneration.According to the theory of motherland's medical science, prescription of the present invention is with reinforcing the kidney and supporting YANG, and promoting blood circulation and stopping pain goes the wind dehumidifying to be the rule of treatment.The present invention is with Cornu Cervi Pantotrichum, Herba Epimedii, Herba Cistanches, the Cortex Eucommiae, Radix Rehmanniae Preparata, reinforcing the kidney and supporting YANG, benefiting essence and marrow, strong rigidity of soft tissues bone.Radix Notoginseng, blood circulation promoting and blood stasis dispelling, pain relieving; Caulis Spatholobi, Rhizoma Drynariae, the meridian dredging, blood circulation and removing stasis can relax.Olibanum, Myrrha promoting blood circulation to remove obstruction in the collateral, pain relieving, blood stasis dispelling.Radix Gentianae Macrophyllae, Radix Angelicae Pubescentis, expelling wind and removing dampness, the Pheretima dispelling wind and removing obstruction in the collateral.Herba Pyrolae, tonify deficiency kidney tonifying, expelling wind and removing dampness, promoting blood flow to regulate menstruation.All medicines share, and play reinforcing the kidney and supporting YANG, promoting blood circulation and stopping pain altogether, the effect of expelling wind and removing dampness.By treatment of the present invention, significantly improved the microcirculation of body tissue, increased the blood flow of body tissue, regulate the metabolism of organic matter and calcium phosphorus, increase osteoarticular nutrition supply, improve the osteocyte metabolic activity, and the anti-wear performance and the shock proof load forces of soft tissue of joint.The present invention has carried out 354 routine clinical observations altogether through Heilongjiang Provincial Hospital, Shangzhi City institute of traditional Chinese medicine.The experiment case all meets the traditional Chinese medical science and Western medicine diagnose standard.Femur head necrosis 54 examples wherein.Prolapse of lumbar intervertebral disc 200 examples, rheumatism, rheumatoid 100 examples; All disease is all made a definite diagnosis with symptom, sign, chemical examination, X line or CT examination mode.Through clinical statistics, total effective rate of the present invention is 97.6%, and cure rate is 80%, and is without any side effects.Method of the present invention can effectively be come out the extracts active ingredients of each flavor medical material, guarantees giving full play to of the property of medicine, equal water soluble of medicine active ingredient of the present invention or ethanol, so the present invention adopts water extracting alcohol precipitation method.Cornu Cervi Pantotrichum, Radix Notoginseng are valuable medicinal, are used as medicine with former powder, can better bring into play its curative effect.The present invention adopts orthogonal design to investigate amount of water, decocting time, the influence of alcohol precipitation concentration to extracting, and optimum is described amount of water of method of the present invention and decocting time, and alcohol precipitation concentration is 60%.
The specific embodiment:
The present invention is a kind of Chinese medicine for the treatment of orthopaedic disease, and the prescription of this medicine and proportioning are: Herba Epimedii 50-80 gram, Radix Gentianae Macrophyllae 60-80 gram, Herba Pyrolae 50-80 gram, Radix Notoginseng 50-80 gram, Radix Rehmanniae Preparata 80-100 gram, Radix Angelicae Pubescentis 50-80 gram, Rhizoma Drynariae 50-100 gram, Herba Cistanches 50-80 gram, Cortex Eucommiae 80-100 gram, Olibanum 80-100 gram, Myrrha 80-100 gram, Caulis Spatholobi 80-100 gram, Cornu Cervi Pantotrichum 10-20 gram, Pheretima 80-100 gram.
Preparation method of the present invention is: A: get the raw materials ready according to following prescription and proportioning: the prescription of this medicine and proportioning are: Herba Epimedii 50-80 gram, Radix Gentianae Macrophyllae 60-80 gram, Herba Pyrolae 50-80 gram, Radix Notoginseng 50-80 gram, Radix Rehmanniae Preparata 80-100 gram, Radix Angelicae Pubescentis 50-80 gram, Rhizoma Drynariae 50-100 gram, Herba Cistanches 50-80 gram, Cortex Eucommiae 80-100 gram, Olibanum 80-100 gram, Myrrha 80-100 gram, Caulis Spatholobi 80-100 gram, Cornu Cervi Pantotrichum 10-20 gram, Pheretima 80-100 gram.It is standby that Radix Notoginseng, Cornu Cervi Pantotrichum are ground into segmentation, mixes after all the other 12 flavor medicine washings and mix thoroughly, and the water of 10 times of amounts of adding decocted 2.5 hours;
B: after obtaining filtrate, in the medical material of decoction liquor, add the water of 5 times of amounts again, decocted 1.5 hours;
C: secondary decocts filtrate merging, and concentrated filtrate to relative density is 1.10-1.15, and measuring temperature is the extractum that 80 degree heat are surveyed, and puts cold;
D: in extractum, slowly add concentration and be 95% ethanol, make to contain the alcohol amount and reach 60, fully stir, left standstill 24 hours;
E: filter, reclaim ethanol, concentrated medicament to relative density is 1.35-1.40, and measuring temperature is the extractum that 80 degree heat are surveyed;
F: behind extract dry, add the former powder of Radix Notoginseng, Cornu Cervi Pantotrichum prepare again, abundant mixing is pulverized, is sieved, encapsulated.
The concrete enforcement of present embodiment is as follows:
The prescription of this medicine and proportioning are:
Herba Epimedii 50 grams, Radix Gentianae Macrophyllae 60 grams, Herba Pyrolae 50 grams, Radix Notoginseng 50 grams, Radix Rehmanniae Preparata 80 grams, Radix Angelicae Pubescentis 60 grams, Rhizoma Drynariae 80 grams, Herba Cistanches 60 grams, the Cortex Eucommiae 80 grams, Olibanum (parched) 80 grams, Myrrha (parched) 80 grams, Caulis Spatholobi 80 grams, Cornu Cervi Pantotrichum 20 grams, Pheretima 80 grams.
Get the raw materials ready according to following prescription and proportioning: the prescription of this medicine and proportioning are: it is standby that Radix Notoginseng, Cornu Cervi Pantotrichum are ground into segmentation, mixes after all the other 12 flavor medicine washings and mix thoroughly, and the water of 10 times of amounts of adding decocted 2.5 hours;
Decoction liquor is filtered and is placed for the first time, and then adds the water of 5 times of amounts in the medical material of decoction liquor, decocted 1.5 hours,
Secondary decocts filtrate merging, and concentrated filtrate to relative density is that 1.10-1.15 measurement temperature is the extractum that 80 degree heat are surveyed, and puts cold;
In extractum, slowly add concentration and be 95% ethanol, make to contain the alcohol amount and reach 60%, fully stir, left standstill 24 hours;
Filter, reclaim ethanol, concentrated medicament to relative density is that 1.35-1.40 measurement temperature is the extractum that 80 degree heat are surveyed;
To be fine powder behind the extract dry, add the former powder of Radix Notoginseng, Cornu Cervi Pantotrichum that has prepared again, abundant mixing, it is encapsulated to pulverize, sieve, and finished product is made in sterilization.
Claims (2)
1, a kind of Chinese medicine for the treatment of orthopaedic disease, it is characterized in that: the prescription of this medicine and proportioning are: Herba Epimedii 50-80 gram, Radix Gentianae Macrophyllae 60-80 gram, Herba Pyrolae 50-80 gram, Radix Notoginseng 50-80 gram, Radix Rehmanniae Preparata 80-100 gram, Radix Angelicae Pubescentis 50-80 gram, Rhizoma Drynariae 50-100 gram, Herba Cistanches 50-80 gram, Cortex Eucommiae 80-100 gram, Olibanum 80-100 gram, Myrrha 80-100 gram, Caulis Spatholobi 80-100 gram, Cornu Cervi Pantotrichum 10-20 gram, Pheretima 80-100 gram.
2, as a kind of preparation method of Chinese medicine for the treatment of orthopaedic disease that claim 1 provided, it is characterized in that:
A: get the raw materials ready according to following prescription and proportioning: the prescription of this medicine and proportioning are: Herba Epimedii 50-80 gram, Radix Gentianae Macrophyllae 60-80 gram, Herba Pyrolae 50-80 gram, Radix Notoginseng 50-80 gram, Radix Rehmanniae Preparata 80-100 gram, Radix Angelicae Pubescentis 50-80 gram, Rhizoma Drynariae 50-100 gram, Herba Cistanches 50-80 gram, Cortex Eucommiae 80-100 gram, Olibanum 80-100 gram, Myrrha 80-100 gram, Caulis Spatholobi 80-100 gram, Cornu Cervi Pantotrichum 10-20 gram, Pheretima 80-100 gram.It is standby that Radix Notoginseng, Cornu Cervi Pantotrichum are ground into segmentation, mixes after all the other 12 flavor medicine washings and mix thoroughly, and the water of 10 times of amounts of adding decocted 2.5 hours;
B: after obtaining filtrate, in the medical material of decoction liquor, add the water of 5 times of amounts again, decocted 1.5 hours;
C: secondary decocts filtrate merging, and concentrated filtrate to relative density is 1.10-1.15, and measuring temperature is the extractum that 80 degree heat are surveyed, and puts cold;
D: in extractum, slowly add concentration and be 95% ethanol, make to contain the alcohol amount and reach 60, fully stir, left standstill 24 hours;
E: filter, reclaim ethanol, concentrated medicament to relative density is 1.35-1.40, and measuring temperature is the extractum that 80 degree heat are surveyed;
F: behind extract dry, add the former powder of Radix Notoginseng, Cornu Cervi Pantotrichum prepare again, abundant mixing is pulverized, is sieved, encapsulated.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031326323A CN1241600C (en) | 2003-09-25 | 2003-09-25 | Chinese medicine for treating osteological diseases and its prepn process |
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| CNB031326323A CN1241600C (en) | 2003-09-25 | 2003-09-25 | Chinese medicine for treating osteological diseases and its prepn process |
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| CN1526431A true CN1526431A (en) | 2004-09-08 |
| CN1241600C CN1241600C (en) | 2006-02-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB031326323A Expired - Fee Related CN1241600C (en) | 2003-09-25 | 2003-09-25 | Chinese medicine for treating osteological diseases and its prepn process |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102846943A (en) * | 2012-09-28 | 2013-01-02 | 郑州中医骨伤病医院 | Femoral head necrosis rehabilitation pill |
| CN111297985A (en) * | 2018-11-26 | 2020-06-19 | 周元宁 | Traditional Chinese medicine preparation capable of relieving and eliminating numbness and swelling pain of various parts of body |
-
2003
- 2003-09-25 CN CNB031326323A patent/CN1241600C/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102846943A (en) * | 2012-09-28 | 2013-01-02 | 郑州中医骨伤病医院 | Femoral head necrosis rehabilitation pill |
| CN102846943B (en) * | 2012-09-28 | 2013-11-20 | 郑州中医骨伤病医院 | Femoral head necrosis rehabilitation pill |
| CN111297985A (en) * | 2018-11-26 | 2020-06-19 | 周元宁 | Traditional Chinese medicine preparation capable of relieving and eliminating numbness and swelling pain of various parts of body |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1241600C (en) | 2006-02-15 |
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