CN1506118A - Disinfectant liquid for digestive tract examining speculum - Google Patents
Disinfectant liquid for digestive tract examining speculum Download PDFInfo
- Publication number
- CN1506118A CN1506118A CNA021358524A CN02135852A CN1506118A CN 1506118 A CN1506118 A CN 1506118A CN A021358524 A CNA021358524 A CN A021358524A CN 02135852 A CN02135852 A CN 02135852A CN 1506118 A CN1506118 A CN 1506118A
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- digestive tract
- speculum
- volatile oil
- disinfectant
- tract examining
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Abstract
The disinfectant liquid for digestive tract examining speculum is prepared with extractive of wormseed as one kind of chenopodiaceae plant. The extractive is volatile oil, and the volatile oil has the main components including ascarisin, p-cymene and terpenes, such as aritasone, limonene, etc. The volatile oil has the functions of expelling wind, killing worm, dredging meridian and stopping pain as well as killing bacteria causing digestive tract disease. The clinical use shows that the volatile oil is one effective medicine and has no damage to body.
Description
The present invention relates to a kind of disinfectant solution that is used to stretch into the disinfectant solution, particularly gastroscope of digestive tract detecting instrument, probe in the human body.
Along with the development of Peep Technology, many instrument detecting devices can stretch in people's the body, carry out the inspection of intracorporeal organ pathological changes, and these apparatus expensive are not disposable uses; After once inspection finished, the reply probe waited and carries out disinfection.Existing disinfectant is chemosterilant mostly, and as sodium hypochlorite, hydrogen peroxide etc., these materials should clean up; Otherwise, enter in the human body, will cause damage to intracorporeal organ; And adopt weak property disinfectant, and then often cause sterilization not thorough, cause cross infection, show according to interrelated data: gastroscope sterilization disqualification rate has reached more than 90%, and the case of the present HP cross infection of China has reached the 60-70% that made the number of checking.At present, the sterilization method time of clinical practice is long, reaches 30 minutes, and it is not thorough that sterilization suppresses to kill HP, and dosage is big.
The objective of the invention is at the problems referred to above, provide a kind of dosage little, have no side effect, easy to use, suppress HP gastroscope disinfectant solution and preparation method thereof rapidly.
A kind of disinfectant solution that is used for digestive tract examining speculum of the present invention is to be made by Herba Chenopodii extract, and it contains Herba Chenopodii extract is 5-90%.
Described disinfectant, its preferred amounts are that to contain Herba Chenopodii extract be 20-80%.
Described disinfectant can be composite with other plant extract or chemosterilant, as the Ramulus et Folium Adinae Piluliferae extract.
Described disinfectant is used to enter the instrument of digestive tract examining, the sterilization of special gastroscope.
Herba Chenopodii is the herb that fruit ear is arranged of chenopod Herba Chenopodii.Herb contains volatile oil 0.4-1%, in the oil main component be ascaridole, to P-cymene and terpenoid substance thereof, as aritasone, limonene etc., have dispel the wind, parasite killing, stimulate the menstrual flow, the analgesic effect.
Report the composite medicine of making of Herba Chenopodii extract and other material in the document formerly, be used for the treatment of peptic ulcer.
The present invention has used the treatment active drug of peptic ulcer separately as entering digestive tract instrument in the body, the disinfectant of gastroscope particularly, obviously, its antibacterial to the digestive tract ulcer has single-minded killing action, simultaneously, owing to itself be a kind of active drug through clinical proof, therefore be well suited for as appropriative disinfector, and the effect that can kill virus rapidly.
The specific embodiment:
The Herba Schizonepetae stem and leaf 500 that fetches earth restrains, and uses steam distillation in the boiler of packing into, extracts Chenopodium Oil 1.6 grams.Extract is pressed 5%, 15,25,35,45,80% concentration, and make emulsifying agent,, promptly make this disinfectant solution with the vegetable oil dilution with yolk.
To the external sensitization test of helicobacter pylori
2-0. raw material
1, medicine of the present invention, i.e. the volatile oil of the foregoing description preparation adds the dilution of refined plant oil, and wherein, volatile oil contents is 0.95mg/ml in the disinfectant solution;
2, bacterial strain: for recently from chronic gastritis patient gastric mucosa biopsy specimen separation and Culture, the typical HP of character totally 6 strains.The solid culture of cultivating 48 hours is used for drug sensitive test through going down to posterity;
2-1. method
Adopt agar dilution, medicine is made emulsifying agent with yolk, and emulsion is sneaked into pour plate in the culture medium respectively after with the sterile purified water doubling dilution.Scrape respectively with inoculating loop and to get test organisms solid culture 1/4 ring and be inoculated in flat board.Through 37 ℃, little aerobic environment (5%O
2, 10%CO
2, 85%N
2) cultivate observed result after 72 hours, the least concentration of contained drug is the minimum inhibitory concentration (MIC) of medicine of the present invention to HP in the no HP growth flat board.
2-2. result
The HP growing state sees the following form, and wherein, "+" is growth, and "-" be not for growing.
The inhibition result of table 7 pair helicobacter pylori
| Bacterial strain number | Drug level (mg/ml) |
| ??24.8??12.4??6.2??3.1?1.55?0.78?0.39?0.194?0.097?0.048?0.024?0.012??…0 | |
| ?92031 ?92082 ?92083 ?92084 ?92085 ?92086 | ????-????-????-????-????-????-????-????-?????-?????-??????+????+??????+ ????-????-????-????-????-????-????-????-?????-?????-??????+????-??????+ ????-????-????-????-????-????-????-????-?????-?????-??????+????+??????+ ????-????-????-????-????-????-????-????-?????-?????-??????-????+??????+ ????-????-????-????-????-????-????-????-?????-?????-??????+????+??????+ ????-????-????-????-????-????-????-????-?????-?????-??????-????+??????+ |
Test shows, on the culture medium that contains medicine 0.48ug/ml concentration of the present invention.6 strain HP all do not grow, on the culture medium of 0.024ug/ml concentration.6 dwarf HP have 3 dwarfs not grow, and 0.012ug/ml and following concentration thereof are to HP unrestraint effect, so MIC is 0.024ug/ml-0.48ug/ml.Show that medicine of the present invention has had strong inhibitory effects to helicobacter pylori.
Claims (5)
1, a kind of disinfectant solution that is used for digestive tract examining speculum is characterized in that it being to be made by Herba Chenopodii extract, and it contains Herba Chenopodii extract is 5-90%.
2, a kind of disinfectant solution that is used for digestive tract examining speculum according to claim 1, it is characterized in that containing Herba Chenopodii extract is 20-80%.
3, a kind of disinfectant solution that is used for digestive tract examining speculum in the body according to claim 1 is characterized in that described disinfectant also contains the Ramulus et Folium Adinae Piluliferae extract.
4, a kind of disinfectant solution that is used for digestive tract examining speculum in the body according to claim 1 is characterized in that described disinfectant also contains chemosterilant.
5, a kind of disinfectant solution that is used for digestive tract examining speculum in the body according to claim 1 is characterized in that described disinfectant is used for the sterilization of gastroscope.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA021358524A CN1506118A (en) | 2002-12-06 | 2002-12-06 | Disinfectant liquid for digestive tract examining speculum |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA021358524A CN1506118A (en) | 2002-12-06 | 2002-12-06 | Disinfectant liquid for digestive tract examining speculum |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1506118A true CN1506118A (en) | 2004-06-23 |
Family
ID=34231529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA021358524A Pending CN1506118A (en) | 2002-12-06 | 2002-12-06 | Disinfectant liquid for digestive tract examining speculum |
Country Status (1)
| Country | Link |
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| CN (1) | CN1506118A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007076699A1 (en) * | 2005-12-31 | 2007-07-12 | Tianjin Tasly Pharmaceutical Co. Ltd., China | Pharmaceutical composition containing chenopodium ambrosioides extract and its preparing process and application |
| CN1990007B (en) * | 2005-12-31 | 2011-08-10 | 天津天士力制药股份有限公司 | Composition for treating stomachache, its preparation method and uses |
| CN101675924B (en) * | 2008-09-19 | 2013-06-05 | 天士力制药集团股份有限公司 | Application of ascaridol in preparing medicine for preventing helicobacter pylori and treating disease caused by helicobacter pylori |
-
2002
- 2002-12-06 CN CNA021358524A patent/CN1506118A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007076699A1 (en) * | 2005-12-31 | 2007-07-12 | Tianjin Tasly Pharmaceutical Co. Ltd., China | Pharmaceutical composition containing chenopodium ambrosioides extract and its preparing process and application |
| CN1990007B (en) * | 2005-12-31 | 2011-08-10 | 天津天士力制药股份有限公司 | Composition for treating stomachache, its preparation method and uses |
| US8361515B2 (en) | 2005-12-31 | 2013-01-29 | Tasly Pharmaceutical Group Co., Ltd. | Extracts of Chenopodium ambrosioides L., the compositions comprising said extracts, the preparing process and application thereof |
| US8586108B2 (en) | 2005-12-31 | 2013-11-19 | Tasly Pharmaceutical Group Co., Ltd | Extracts of Chenopodium ambrosioides L., the compositions comprising said extracts, the preparing process and application thereof |
| CN101675924B (en) * | 2008-09-19 | 2013-06-05 | 天士力制药集团股份有限公司 | Application of ascaridol in preparing medicine for preventing helicobacter pylori and treating disease caused by helicobacter pylori |
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