CN1486732A - Hypoglycemic oral liquid prepn and its production process - Google Patents
Hypoglycemic oral liquid prepn and its production process Download PDFInfo
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- CN1486732A CN1486732A CNA031419623A CN03141962A CN1486732A CN 1486732 A CN1486732 A CN 1486732A CN A031419623 A CNA031419623 A CN A031419623A CN 03141962 A CN03141962 A CN 03141962A CN 1486732 A CN1486732 A CN 1486732A
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Abstract
The present invention relates to medicine technology and is especially one kind of hypoglycemic oral liquid preparation and its production process. It is prepared with ten kinds of Chinese medicinal materials, including astragalus root, Chinese yam, rehmannia root, schisandra, ophiopogon root, etc. as well as supplementary material. The preparation process includes mixing the medicine material, twice decoction, merging medicine liquid, concentration, clarifying via adding clarifying agent, 200-mesh sieving, stagnation, adding supplementary material, packing and sterilizing. Compared with available technology, the present invention has the advantages of selecting treatment based on different diagnosis, comprehensive balance, smooth curative effect, less side effect, etc.
Description
[technical field]
The present invention relates to medical technical field, a kind of specifically hypoglycemic oral liquid formulation and production method.
[technical background]
Diabetes are common clinical and frequently-occurring disease, and because of its pathogeny complexity, the influence factor is more, so never have ideal Therapeutic Method and medicine.Blood sugar increasing is the performance of diabetics main clinical.Along with the raising of expanding economy and people's living standard, the sickness rate of diabetes is more and more higher, and the trend that becomes younger is arranged, and is having a strong impact on people's quality of life.The medicine of existing treatment diabetes (type ii diabetes) as Thiourea, biguanides etc., need take for a long time, and side effect is big, and blood glucose can quick rebound after the drug withdrawal, and curative effect is unsatisfactory.
[summary of the invention]
The purpose of this invention is to provide a kind of determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, aggregate balancing, curative effect is steady, side effect is little a kind of hypoglycemic oral liquid formulation and production method.
For achieving the above object, a kind of hypoglycemic oral liquid formulation, comprise the Radix Astragali, Rhizoma Dioscoreae, the Radix Rehmanniae, Fructus Schisandrae Chinensis, Radix Ophiopogonis, Fructus Mume, Rhizoma Polygonati, Fructus Lycii, Radix Puerariae, Folium Mori and adjuvant etc., it is characterized in that the portion rate of preparing is made up of 3 parts of the Radixs Astragali, 2 parts of Rhizoma Dioscoreaes, 2 parts in the Radix Rehmanniae, 2 parts of Fructus Schisandrae Chinensis, 1 part of Radix Ophiopogonis, 1 part of Fructus Mume, 1.5 parts of Rhizoma Polygonatis, 1.5 parts of Fructus Lyciis, 1 part of Radix Puerariae, 1 part on Folium Mori and adjuvant.Described adjuvant portion rate can be correctives protein sugar or stevioside 0.04-0.12 part, preservative sodium benzoate or nipalgin 0.1-0.5 part.The production method of hypoglycemic oral liquid formulation is medicine is prepared burden, and adds 10 times of water gagings and soaks 1 hour, after frying in shallow oil 1 hour, taking liquid adds 8 times of water gagings again and fries in shallow oil 1 hour taking liquid, merge twice and be concentrated into 1: 5 medicinal liquid of crude drug concentration, add clarifier again, cross 200 mesh sieves, left standstill 3-5 hour, add adjuvant, mix homogeneously, packing, sterilization gets product.
The present invention compare with prior art have determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, aggregate balancing, advantage such as curative effect is steady, side effect is little.Use modern preparation technique traditional traditional Chinese medical science proved recipe is developed to take, easy to carry, mouthfeel is good, oral liquid formulations that can long preservation will have important clinical meaning and good economic outlook.
[description of drawings]
Fig. 1 is a process chart of the present invention.
Referring to Fig. 1: 1 adds 10 times of water gagings soaked 1 hour, fried in shallow oil 1 hour, extracted medicinal liquid, 2 and added 8 times of water yields and fried in shallow oil 1 hour, extract medicinal liquid, 3 and merge medicinal liquid, 4 concentrated medicaments, 5 adding clarifiers, cross 200 orders, leave standstill 3-5 hour, 6 adding adjuvants, mix homogeneously, 7 packing, sterilization
[embodiment]
With Radix Astragali 300g, Rhizoma Dioscoreae 200g, Radix Rehmanniae 200g, Fructus Schisandrae Chinensis 200g, Radix Ophiopogonis 100g, Fructus Mume 100g, Rhizoma Polygonati 150g, Fructus Lycii 150g, Radix Puerariae 100g, all medical materials of Folium Mori 100g put and decoct with water 10,8 times in the extraction pot, each 1 hour.Merge the water extract, be concentrated into crude drug concentration 1: 5.Heating is 120 minutes under 80 ℃ of stirring addings of temperature clarifier A2g constant temperature, stirred once in per 30 minutes, add clarifier B2g then, stirred once in per 30 minutes, cross 200 mesh sieves after 1 hour, static 3-5 hour, add protein sugar 8g, sodium benzoate 12g, mix homogeneously, packing, sterilization gets product.
Claims (3)
1, a kind of hypoglycemic oral liquid formulation, comprise the Radix Astragali, Rhizoma Dioscoreae, the Radix Rehmanniae, Fructus Schisandrae Chinensis, Radix Ophiopogonis, Fructus Mume, Rhizoma Polygonati, Fructus Lycii, Radix Puerariae, Folium Mori and adjuvant etc., it is characterized in that the portion rate of preparing is made up of 3 parts of the Radixs Astragali, 2 parts of Rhizoma Dioscoreaes, 2 parts in the Radix Rehmanniae, 2 parts of Fructus Schisandrae Chinensis, 1 part of Radix Ophiopogonis, 1 part of Fructus Mume, 1.5 parts of Rhizoma Polygonatis, 1.5 parts of Fructus Lyciis, 1 part of Radix Puerariae, 1 part on Folium Mori and adjuvant.
2, hypoglycemic oral liquid formulation as claimed in claim 1 is characterized in that described adjuvant portion rate can be correctives protein sugar or stevioside 0.04-0.12 part, preservative sodium benzoate or nipalgin 0.1-0.5 part.
3, the production method of hypoglycemic oral liquid formulation as claimed in claim 1 is characterized in that medicine is prepared burden, and adds 10 times of water gagings and soaks 1 hour, after frying in shallow oil 1 hour, taking liquid adds 8 times of water gagings again and fries in shallow oil 1 hour taking liquid, merge twice and be concentrated into 1: 5 medicinal liquid of crude drug concentration, add clarifier again, cross 200 mesh sieves, left standstill 3-5 hour, add adjuvant, mix homogeneously, packing, sterilization gets product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031419623A CN1330351C (en) | 2003-07-30 | 2003-07-30 | Hypoglycemic oral liquid prepn and its production process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031419623A CN1330351C (en) | 2003-07-30 | 2003-07-30 | Hypoglycemic oral liquid prepn and its production process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1486732A true CN1486732A (en) | 2004-04-07 |
| CN1330351C CN1330351C (en) | 2007-08-08 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB031419623A Expired - Fee Related CN1330351C (en) | 2003-07-30 | 2003-07-30 | Hypoglycemic oral liquid prepn and its production process |
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| CN (1) | CN1330351C (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101143180B (en) * | 2006-09-12 | 2011-06-29 | 石药集团中奇制药技术（石家庄）有限公司 | Medicine for treating diabetes |
| CN102397459A (en) * | 2011-10-19 | 2012-04-04 | 李顺光 | Traditional Chinese medicine for treating diabetes and preparation method thereof |
| CN102524790A (en) * | 2012-03-19 | 2012-07-04 | 肖梅芬 | Medicine-food dual-purpose sugar-reducing series foods and preparation method thereof |
| CN102551065A (en) * | 2012-03-19 | 2012-07-11 | 肖梅芬 | Blood sugar reducing food series |
| CN102614359A (en) * | 2012-04-23 | 2012-08-01 | 侯温军 | Chinese medicinal preparation for treating diabetes and preparation method thereof |
| CN102614327A (en) * | 2012-04-27 | 2012-08-01 | 陈本善 | Medicine for treating hyperglycemia |
| CN105265947A (en) * | 2015-09-10 | 2016-01-27 | 河南爱因糖尿病健康科学研究院股份有限公司 | Plant beverage for improving constitution of patients with hyperglycemia and diabetes mellitus |
| CN108553584A (en) * | 2018-06-19 | 2018-09-21 | 延边大学 | A kind of composition of auxiliary hyperglycemic and its application |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1067562C (en) * | 1996-10-09 | 2001-06-27 | 刘爱国 | Method for preparation of Tangniaokang medicine for curing diabetes |
-
2003
- 2003-07-30 CN CNB031419623A patent/CN1330351C/en not_active Expired - Fee Related
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101143180B (en) * | 2006-09-12 | 2011-06-29 | 石药集团中奇制药技术（石家庄）有限公司 | Medicine for treating diabetes |
| CN102397459A (en) * | 2011-10-19 | 2012-04-04 | 李顺光 | Traditional Chinese medicine for treating diabetes and preparation method thereof |
| CN102524790A (en) * | 2012-03-19 | 2012-07-04 | 肖梅芬 | Medicine-food dual-purpose sugar-reducing series foods and preparation method thereof |
| CN102551065A (en) * | 2012-03-19 | 2012-07-11 | 肖梅芬 | Blood sugar reducing food series |
| CN102524790B (en) * | 2012-03-19 | 2013-06-12 | 肖梅芬 | Medicine-food dual-purpose sugar-reducing series foods and preparation method thereof |
| CN102614359A (en) * | 2012-04-23 | 2012-08-01 | 侯温军 | Chinese medicinal preparation for treating diabetes and preparation method thereof |
| CN102614359B (en) * | 2012-04-23 | 2013-12-25 | 侯温军 | Traditional Chinese medicine preparation for treating diabetes and preparation method thereof |
| CN102614327A (en) * | 2012-04-27 | 2012-08-01 | 陈本善 | Medicine for treating hyperglycemia |
| CN105265947A (en) * | 2015-09-10 | 2016-01-27 | 河南爱因糖尿病健康科学研究院股份有限公司 | Plant beverage for improving constitution of patients with hyperglycemia and diabetes mellitus |
| CN105265947B (en) * | 2015-09-10 | 2018-02-06 | 河南爱因糖尿病健康科学研究院股份有限公司 | A kind of plant beverage for improving hyperglycaemia and diabetes patient's constitution |
| CN108553584A (en) * | 2018-06-19 | 2018-09-21 | 延边大学 | A kind of composition of auxiliary hyperglycemic and its application |
| CN108553584B (en) * | 2018-06-19 | 2021-01-01 | 延边大学 | Composition for assisting in reducing blood sugar and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1330351C (en) | 2007-08-08 |
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Owner name: SUZHOU YUSEN NEW MEDICINE DEVELOPMENT CO., LTD. Free format text: FORMER OWNER: SHANGHAI YUSEN NEW MEDICINE DEVELOPMENT CO., LTD. Effective date: 20080530 |
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Address after: Xinghu Street Industrial Park of Suzhou city in Jiangsu province 215123 bio nano science & Technology Park 218 C30 Patentee after: Suzhou Youseen New Drug R & D Co., Ltd. Address before: Xinghu street Suzhou Industrial Park in Jiangsu province 215123 No. 218 nano Biotechnology Park A3 building 313-316 room Patentee before: Suzhou Youseen New Drug R & D Co., Ltd. |
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