CN1454607A - Medicine for curing cervicitis and preparing method thereof - Google Patents

Medicine for curing cervicitis and preparing method thereof Download PDF

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CN1454607A
CN1454607A CN02110318A CN02110318A CN1454607A CN 1454607 A CN1454607 A CN 1454607A CN 02110318 A CN02110318 A CN 02110318A CN 02110318 A CN02110318 A CN 02110318A CN 1454607 A CN1454607 A CN 1454607A
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medicine
cervicitis
cortex phellodendri
treatment
radix
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CN1199669C (en
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韩维国
韩军峰
韩少峰
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韩维国
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Abstract

The invention discloses a kind of medicine for curing cervicities and the manufacturing method. The raw material comprises: amboyna 5-20, kuh-seng 10-25, radix stemonae 10-15, azedarach 5-10, plum, slices 0.5-10, selinum 10-25, alum 3-5, bezoar 0.01-0.1, cutch 5-40, pill powder 2-5. The radix stemonae, amboyna, selinum, kuh-seng, azedarach guava husk are sliced into pieces and is soaked in water, they are boiled by high heat and decocted by slow fire till that the finger feel sticky when entering it, the medicine liquid is filtered, when the temperature decreases to 50 deg.C, the pill powder is added in by 1:1000 and is blended fully, the plum slices, mastic, myrrh, cutch and alum are crushed and filtered according to the proportion, and they are poured into the medicament liquid and mixed into paste, then produced into suppository.

Description

A kind of medicine and preparation method for the treatment of cervicitis
Affiliated technical field
The invention belongs to the drug invention technical field, what relate generally to is a kind of medicine and preparation method for the treatment of cervicitis.
Background technology
Cervicitis (cervical erosion) is the frequently-occurring disease of harm WomanHealth, can be divided into one, two, three degree by the size and the degree of depth of its inflammatory lesion scope.Cardinal symptom is: symptoms such as leucorrhea, fulminant leucorrhagia with yellowish discharge, lower abdomen dull pain, chronic problem, menoxenia, mind anxiety often appear in the patient.If can not get radical cure for a long time can bring out and be cervical cancer.Sending out the age well, many this disease accounts for the over half of this age bracket between 25-50 year, and is about about 60%, and rural women's sickness rate is higher than the city.At present, clinical to this type of sick therapy nothing more than fulgerize, freezing, laser, flushing and injection antibiotics, not only waste time and energy, expensive bigger, and curative effect is unreliable.
Summary of the invention
Purpose of the present invention promptly produces thus, proposes a kind of medicine and preparation method for the treatment of cervicitis, makes its this medicine can not only play putrefaction removing and tissue regeneration promoting, Yin Yang balancing, the effect of dredging the meridian, and also curative effect is reliably easy to use, has no side effect.
For achieving the above object, solution of the present invention is based on motherland's medical science to pathogenetic understanding of cervicitis and Therapeutic Principle, forms with reference to modern pharmacological research.
The present invention makes (consumption is a weight portion) by following component: the red powder 2-5 of Cortex Phellodendri 5-20 Radix Sophorae Flavescentis 10-25 Radix Stemonae 10-15 melia 5-10 borneol 0.5-1.0 Fructus Cnidii 10-25 Alumen 3-5 Calculus Bovis 0.05-0.1 catechu 5-40.
Formula optimization weight (part) ratio range of preparation medicine of the present invention is: the red powder 3-4 of Cortex Phellodendri 8-15 Radix Sophorae Flavescentis 15-20 Radix Stemonae 12-14 melia 7-9 borneol 0.6-0.9 Fructus Cnidii 15-20 Alumen 3-5 Calculus Bovis 0.06-0.08 catechu 20-30.
The optimum weight of medicine of the present invention (part) ratio range is: Cortex Phellodendri 10 Radix Sophorae Flavescentiss 15 Radixs Stemonae 12 melias 8 borneol 0.8 Fructus Cnidii 15 Alumen 4 Calculus Boviss 0.08 catechu 20 red powder 3.
Above-mentioned each component is made medicine production method of the present invention is: after the Radix Stemonae, Cortex Phellodendri, Fructus Cnidii, Radix Sophorae Flavescentis, Fructus Toosendan root bark, Pericarpium Granati section are soaked in water, boil with high heat and use slow fire instead and decoct after finger immerses and have bonding sense to be advisable, with medical filtration, put into red powder and mixing for standby use fully in 1: 1000 ratio when treating that the medicine temperature is reduced to 50 ℃ of left and right sides.
Borneol, Olibanum, Myrrha, catechu, Alumen are mixed in proportion grinding and sieving, pour in the prefabricated medicinal liquid and stir into pasty state, be prepared into suppository.
The present invention is according to the combination principle scientific composition of motherland's medical science " monarch, minister, help, make " mutual reinforcement between, the mutual-assistance.The selected medical material overwhelming majority is natural poisonous ore deposit, plant medicine material, in concocting process with in the careful operating process that intense fire Cui is boiled, slow fire refines, the natural medicinal liquid that stimulates membranous part to divide will be arranged, purify after filtration,, remove the medicinal liquid that toxin extracts the soda acid appropriateness that is fit to the intravaginal environment, its " PH " is worth between 6.0-1.010.
Selected Cortex Phellodendri is the bark that Rutaceae deciduous tree plant (Cortex Phellodendri) and wampee (Cortex Phellodendri) are removed cork.Main product is in China northeast, North China, the Inner Mongol and other places.Clear and Bright, bark was taked in front and back, dried to flatten to give birth to and used or salt stir-fry usefulness.The nature and flavor bitter cold is returned kidney, bladder, large intestine channel.Effect: clearing away damp-heat, pathogenic fire purging poison, reducing the asthenic fever.Clinical treatment woman leucorrhea, compatibilities such as many and Semen Ginkgo, Semen Plantaginis are as " yihuang decoction ".Have in " herbal classic " to carry and say: " stagnation of QI heat, woman's whitish metrorrhagia, negative and positive phagedenoma etc. in the main the five internal organs the intestines and stomach "; " Cortex Phellodendri has very wide antibacterial range that dysentery bacterium, Bacillus typhi, escherichia coli, Fructus Vitis viniferae bacillus, bacillus pyocyaneus etc. are had inhibitory action in December, 1978 front page " Chinese materia medica " the 60 one page heat clearing and damp drying heat one chapter introduction according to another Shanghai science tech publishing house.In addition leptospira, A Mima protozoon and dermatophytes there is inhibitory action.External has effects such as the subcutaneous infiltration blood of promotion absorption.
Radix Sophorae Flavescentis: the root of the perennial fallen leaves of pulse family semishrub plant Radix Sophorae Flavescentis.China all produces various places, and spring and autumn is excavated removing LU, given birth to along root and use.The nature and flavor bitter cold, GUIXIN, liver, stomach, large intestine, urinary bladder channel.Effect: heat clearing and damp drying, wind dispelling insecticide, diuresis.Clinical usefulness is controlled the many and Cortex Phellodendri of married woman leucorrhea, the Radix Angelicae Dahuricae, the same usefulness of Fructus Cnidii, and being used for the treatment of trichomonal vaginitis in recent years has good effect, and certain antifungic action is still arranged in addition.
The Radix Stemonae: be the tuber of the climing Radix Stemonae of Stemonaceae herbaceos perennial and radix stemonae tuberosae or Radix Stemonae.Not Radix Stemonae main product China the north, middle part, each province, east; Radix stemonae tuberosae is produced in the Yangtze river basin to Hainan Island; The Radix Stemonae main product in Shandong, Henan to Yangtze river basin middle and lower reaches and Fujian.Excavate autumn, gives birth to and use or processed with honey.Nature and flavor are sweet, flat, bitter, return lung.Effect: nourishing the lung to arrest cough, kill the louse parasite killing.The Radix Stemonae contains (-)-Stemoninine, and some dermatophytes is had inhibitory action; Radix Stemonae alcohol extract has killing action to trichomonas vaginitis, and is comparatively commonly used clinically.
Melia: be the root bark of Meliaceae magaphanerophytes chinaberry and Fructus Toosendan tree.There is distribution in most of area, the whole nation, can adopt at any time, scrapes off cork using fresh herb or dry product and runs through usefulness.The nature and flavor bitter cold, poisonous, return liver, spleen, stomach warp.Effect: parasite killing, treatment scabies.Clinical except that being used for intestinal parasitical diseases, this product external also has therapeutical effect to trichomonal vaginitis; Its water logging agent still has inhibitory action to dermatophytes.
Borneol (having another name called Borneolum Syntheticum): the crystallization of staying cooling to get through steaming for the trunk of the fragrant section of Borneolum Syntheticum brain aiphyllium Borneolum Syntheticum.Now how to make through chemical reaction with Oleum Terebinthinae and Camphora, it is airtight that finished product is stored in shady and cool place, and the time spent can not be used through scorching, levigation.The nature and flavor tepor of working hard, GUIXIN, spleen, lung meridian.Effect: the refreshment of having one's ideas straightened out, clearing away heat-damp and promoting diuresis.Clinical external has heat-clearing and toxic substances removing and gentle antisepsis and bacteriostasis.
Fructus Cnidii: be the fruit of Umbelliferae annual herb plant cnidium monnieri, China all produces various places, is many with Guangxi, Guangdong, Jiangxi and other places, and the autumn in summer extracts full pearl during fruit maturation, dries, and lays fruit and gives birth to and use.Property and flavor of peppery and warm.Effect: warming the kidney to invigorate YANG, (external) removing dampness and killing parasites.The clinical married woman of being used for leucorrhea, pudendal pruritus or vaginal eczema, skin ulcer tinea disease such as itch.This product has inhibitory action to trichomonas vaginitis, pathogenic dermatophytes, and can reduce the rheuminess thing or penetrate thing, treatment leucorrhea, pudendal pruritus can with decoction being used as a lotion such as the Radix Stemonae, Radix Sophorae Flavescentis, Pericarpium Zanthoxyli.Recent study proof is made sheet, suppository external curing trichomonal vaginitis with this product to be had in the certain curative effect " big bright book on Chinese herbal medicine " and says: " controlling ... exudative dermatitis leucorrhea with red and white discharge "; Say again in " herbal classic ": " swollen painful in housewife people's the moon ... the pruritus due to damp pathogen malignant boil ".
Pericarpium Granati: be the peel of Punicaceae machaka or dungarunga plant Punica granatum L..There is cultivation in the most of area of China.Peel dries usefulness after adopting standing grain mature peel or food.The sour and astringent temperature of nature and flavor is returned large intestine channel.Effect: antidiarrheal, parasite killing.Clinical practice is sour and astringent because of its nature and flavor, so be used for some erosions, ulcer and ooze out tangible skin ulcer face etc. to play the merit of convergence.Say according to another carrying in the Compendium of Material Medica: " antidiarrheal dysentery, hematochezia, metrorrhagia leukorrhagia ".
Alumen: be the refinement product of alunite---name Bai Fan.Main product in Hubei, ground such as Anhui, Zhejiang, Fujian.Make with or fire forge and remove its water of crystallization, be dried Alumen, grind usefulness into powder.It is cold that nature and flavor are sour and astringent, returns large intestine, Liver Channel.Effect: astringing to arrest bleeding, relieving diarrhea with astringents, the expectorant that dispels the wind, removing dampness are antipruritic.Clinical practice, there is the removing dampness itching-relieving action in local external use.And can be used for the many and sulfur of diseases such as some too fat to move sores, eczema, scabies, Realgar, Borneolum Syntheticum, Plumbum preparatium, Cortex Phellodendri, Indigo Naturalis etc. and grind same usefulness into powder, curative effect is quite good.According to another saying in the ancient Chinese prose record " herbal classic ": " main cold and heat are let out dysentery, erosion of the vulva malignant boil ... "; Say again in the Compendium of Material Medica: " the dicynone carbuncle, meat is disliked in erosion, gives birth to good meat, controls too fat to move malignant boil ... ".
Calculus Bovis: be the intrafascicular calculus of bovid Fel Bovis seu Bubali, i.e. natural Calculus Bovis.All parts of the country are all produced with northwest, southwest, northeast and other places more, when slaughtering an ox, as find existing Calculus Bovis, and elimination bile takes out Calculus Bovis immediately, wraps up in Medulla Junci or Medulla Tetrapanacis silk, and outer bread is with calico or writing paper made from bamboo.Hang shady and cool place.The cold of nature and flavor bitter cold, GUIXIN, Liver Channel.Effect: endogenous wind stopping relieving convulsion, waking up the patient from unconsciousness by dissipating phlegm, heat-clearing and toxic substances removing.Clinically go into the external of ball powder, swell and ache, rot and carbuncle subcutaneous ulcer furuncle poison etc. has certain curative effect for mucocutaneous due to some pyretic toxicity pent-ups.
Plumbum preparatium:, be the oxide of lead for having another name called the Plumbum preparatium.Main product is in Guangdong, Henan and other places, and is former medicinal or fry and use.The nature and flavor suffering is slightly cold, GUIXIN, Liver Channel.Effect: external removing toxic substances and promoting granulation, section disease for oral administration.Clinical external has that good detoxifcation is anticorrosion, antipruritic, the effectiveness of convergence granulation promoting is in various skin ulcers, yellow fluid eczema, ulcer disease such as do not close up for a long time.The Plumbum preparatium external still has the effect of protection skin ulcer face in addition.Compendium of Material Medica is controlled the allusion quotation chickenpox and promptly is equipped with pine, Alumen etc. with this product and makes the cream external application.Note is said in the Compendium of Material Medica: " blood stasis removing is drawn out pus by applying a plaster to the affected part, put on flesh to the energy heat clearing away so control the malignant boil toxic swelling "; According to another note " soft extracts pain relieving granulation promoting " in " property of medicine opinion ".
The present invention is a suppository, putting into vagina liquefied gradually and plays a role under the body temperature effect after two hours, the active ingredient of medicine is attached on the intravaginal pathological tissues, pathological tissues is carried out strong infiltration, play the effect that pathological tissues and normal structure are peeled away, and it is excreted as scalpel; Can finish treatment in 2-5 days, the person of being in a bad way as II-III degree cervicitis can be complete the degenerative tissue of discharge as Ovum crusta Gallus domesticus, play putrefaction removing and tissue regeneration promoting, Yin Yang balancing, dredging the meridian and play the effect that gives protection against cancer in possible trouble.Think from modern medical theory: it has the stable and continuity of repair cell, protection dna molecular chain, and the stability of protection normal tissue cell film reduces the cell mutagenesis factor that causes because of secular inflammatory stimulus.Can block the affinity between rotten tissue of inactivation and normal structure, make it to separate, " FA " the most at last (regression devitalized tissue) excretes, and makes the normal function of body recovery.Cervix uteri presents ruddy glossy health tissues, and effective percentage reaches more than 95%.
The present invention is adapted to all kinds of vaginitiss: as nonspecific vaginitis, trichomonal vaginitis, colpitis mycotica, amebic vaginitis, vaginitis hemoptulus vaginalis, gonococcus and chronic nongonococcal vaginitis.Cervicitis: I-III degree cervical erosion.
Using method: stype is sent into cervix uteri mouth place, block stype in order to avoid overflow external with having the Disinfectant absorbent cotton of pulling strings.This medicine promptly begins liquefaction in intravaginal about two hours, all liquefaction in ten hours, and play therapeutical effect after eight hours is pulled out cotton balls, and twenty four hours to the five days plays a role the stage for drug effect.Degenerative tissue is discharged successively and is finished in one week, finishes the treatment overall process.
Cervix uteri one of early stage usefulness once rotten to the corn or two degree erosions can be cured, and two degree and three degree cervical erosion can be cured with two.
Model case:
Mrs Wang, lower abdominal pain, lumbago, leucorrhea alternately 10 years, dysmenorrhea companion menoxenia.After using medicine of the present invention, check to medical treatment after three and half courses of treatment: body Intramedullary Cysts and long-pending stagnation resolvation are lost, and three degree cervical erosion are fully recovered.
The specific embodiment
Present embodiment mainly is made up of following dosage (weight portion): Cortex Phellodendri 10 Radix Sophorae Flavescentiss 15 Radixs Stemonae 10 melias 8 borneol 0.8 Fructus Cnidii 15 Alumen 4 Calculus Boviss 0.08 catechu 20 red powder 3.
After the Radix Stemonae, Cortex Phellodendri, Fructus Cnidii, Radix Sophorae Flavescentis, Fructus Toosendan root bark, Pericarpium Granati section be soaked in water 72 hours, boil with high heat and use slow fire instead and decoct after finger immerses and have bonding sense to be advisable, with medical filtration, put into red powder and mixing for standby use fully in 1: 1000 ratio when treating that the medicine temperature is reduced to 50 ℃ of left and right sides.
Borneol 10: 1, Olibanum 10: 1, Myrrha 10: 1, catechu 10: 5, Alumen by above mixed are pulverized back at 10: 4 cross 150 mesh sieves, pour in the prefabricated medicinal liquid and stir into pasty state, postforming is diffusing to be as the criterion humidity to hold, an amount of Tween 80 (antiseptic) is put into wherein, be prepared into suppository, about every heavily about 5 grams.Suppository is put under the uviol lamp irradiation about 10 hours, with sealing with wax or the plastic foil vacuum packaging.

Claims (7)

1, a kind of medicine for the treatment of cervicitis is characterized in that: it is the medicament of being made by the following weight proportion raw material: the red powder 2-5 of Cortex Phellodendri 5-20 Radix Sophorae Flavescentis 10-25 Radix Stemonae 10-15 melia 5-10 borneol 0.5-1.0 Fructus Cnidii 10-25 Alumen 3-5 Calculus Bovis 0.05-0.1 catechu 5-40.
2, mend the medicine that requires 1 described treatment cervicitis according to power, wherein the weight proportion of each raw material is: the red powder 3-4 of Cortex Phellodendri 8-15 Radix Sophorae Flavescentis 15-20 Radix Stemonae 12-14 melia 7-8 borneol 0.6-0.9 Fructus Cnidii 15-20 Alumen 3-5 Calculus Bovis 0.06-0.08 catechu 20-30.
3, the medicine of treatment cervicitis according to claim 1, its feature in: the optimum weight proportioning of each raw material is: Cortex Phellodendri 10 Radix Sophorae Flavescentiss 15 Radixs Stemonae 12 melias 7 borneol 0.8 Fructus Cnidii 15 Alumen 4 Calculus Boviss 0.08 catechu 20 red powder 3.
4, according to the medicine of claim 1 or 2 or 3 described treatment cervicitises, it is characterized in that: said medicament is a suppository.
5, the preparation method of treatment cervicitis medicine according to claim 4, it is characterized in that: after the Radix Stemonae, Cortex Phellodendri, Fructus Cnidii, Radix Sophorae Flavescentis, Fructus Toosendan root bark, Pericarpium Granati section are soaked in water, boil with high heat and use slow fire instead and decoct after finger immerses and have bonding sense to be advisable, with medical filtration, put into red powder and mixing for standby use fully in 1: 1000 ratio when treating that the medicine temperature is reduced to 50 ℃ of left and right sides; Borneol, Olibanum, Myrrha, catechu, Alumen are mixed in proportion grinding and sieving, pour in the prefabricated medicinal liquid and stir into pasty state, be prepared into suppository.
6, the preparation method of treatment cervicitis medicine according to claim 5 is characterized in that: the described Radix Stemonae, Cortex Phellodendri, Fructus Cnidii, Radix Sophorae Flavescentis, Fructus Toosendan root bark, Pericarpium Granati section were soaked in water 72 hours.
7, the preparation method of treatment cervicitis medicine according to claim 5 is characterized in that: every heavy 5 grams of described suppository.
CNB021103186A 2002-04-30 2002-04-30 Medicine for curing cervicitis and preparing method thereof Expired - Fee Related CN1199669C (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1321655C (en) * 2005-01-14 2007-06-20 贵州远程制药有限责任公司 Gel of Chinese traditional medicine for treating cervicitis, colpitis and preparing method
CN103445904A (en) * 2013-09-25 2013-12-18 桂林恒保健康用品有限公司 Condom capable of treating cervicitis
CN104367738A (en) * 2014-07-29 2015-02-25 天津泰源中草药技术开发有限公司 Cell-energy skin-care liquid
CN107412528A (en) * 2017-08-08 2017-12-01 江西师范高等专科学校 A kind of pill for treating cervicitis

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1321655C (en) * 2005-01-14 2007-06-20 贵州远程制药有限责任公司 Gel of Chinese traditional medicine for treating cervicitis, colpitis and preparing method
CN103445904A (en) * 2013-09-25 2013-12-18 桂林恒保健康用品有限公司 Condom capable of treating cervicitis
CN103445904B (en) * 2013-09-25 2015-05-13 桂林恒保健康用品有限公司 Condom capable of treating cervicitis
CN104367738A (en) * 2014-07-29 2015-02-25 天津泰源中草药技术开发有限公司 Cell-energy skin-care liquid
CN107412528A (en) * 2017-08-08 2017-12-01 江西师范高等专科学校 A kind of pill for treating cervicitis

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