CN1431898A - 使用青霉胺治疗dna损伤所致疾病的方法 - Google Patents

使用青霉胺治疗dna损伤所致疾病的方法 Download PDF

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Publication number
CN1431898A
CN1431898A CN01810329A CN01810329A CN1431898A CN 1431898 A CN1431898 A CN 1431898A CN 01810329 A CN01810329 A CN 01810329A CN 01810329 A CN01810329 A CN 01810329A CN 1431898 A CN1431898 A CN 1431898A
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Prior art keywords
age
beracilline
reaction
protein
beta
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Pending
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CN01810329A
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English (en)
Chinese (zh)
Inventor
迈伦·K·雅各布森
伊莱恩·L·雅各布森
乔治·T·旺德雷克
丹尼尔·塞万提斯-劳里恩
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NIADYNE CORP
University of Kentucky Research Foundation
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NIADYNE CORP
University of Kentucky Research Foundation
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Publication of CN1431898A publication Critical patent/CN1431898A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN01810329A 2000-04-14 2001-04-16 使用青霉胺治疗dna损伤所致疾病的方法 Pending CN1431898A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19721600P 2000-04-14 2000-04-14
US60/197,216 2000-04-14

Publications (1)

Publication Number Publication Date
CN1431898A true CN1431898A (zh) 2003-07-23

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ID=22728499

Family Applications (1)

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CN01810329A Pending CN1431898A (zh) 2000-04-14 2001-04-16 使用青霉胺治疗dna损伤所致疾病的方法

Country Status (6)

Country Link
EP (1) EP1274418A4 (de)
JP (1) JP2003530434A (de)
CN (1) CN1431898A (de)
AU (2) AU5353901A (de)
MX (1) MXPA02010182A (de)
WO (1) WO2001078718A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7622117B2 (en) * 2002-04-17 2009-11-24 Dynamis Therapeutics, Inc. 3-deoxyglucosone and skin
JP4985214B2 (ja) * 2007-08-20 2012-07-25 ソニー株式会社 レーザーを用いた生体物質検出方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070483A (en) * 1975-06-30 1978-01-24 Sidney Lerman Method of administering a human ocular treating agent and product therefor
US5334617A (en) * 1984-03-19 1994-08-02 The Rockefeller University Amino acids useful as inhibitors of the advanced glycosylation of proteins
DE4228455A1 (de) * 1992-08-26 1994-09-15 Beiersdorf Ag Kosmetische und dermatologische Lichtschutzformulierungen mit einem Gehalt an Thiolen und/oder Thiolderivaten
JPH1053516A (ja) * 1996-05-20 1998-02-24 Shiseido Co Ltd 抗老化皮膚外用剤及びコラーゲン架橋防止用皮膚外用剤
CN1205480C (zh) * 2000-04-14 2005-06-08 尼亚戴恩公司 蛋白质高级糖化终产物(蛋白质-age)形成的调节物的鉴定方法

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Publication number Publication date
AU2001253539B2 (en) 2005-08-04
AU5353901A (en) 2001-10-30
WO2001078718A1 (en) 2001-10-25
EP1274418A1 (de) 2003-01-15
JP2003530434A (ja) 2003-10-14
EP1274418A4 (de) 2005-02-09
MXPA02010182A (es) 2004-08-19

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