CN1425133A - 检测和识别试样中分子事件的系统和方法 - Google Patents
检测和识别试样中分子事件的系统和方法 Download PDFInfo
- Publication number
- CN1425133A CN1425133A CN00817005A CN00817005A CN1425133A CN 1425133 A CN1425133 A CN 1425133A CN 00817005 A CN00817005 A CN 00817005A CN 00817005 A CN00817005 A CN 00817005A CN 1425133 A CN1425133 A CN 1425133A
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- molecular
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0673—Handling of plugs of fluid surrounded by immiscible fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
- B01L2400/0418—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electro-osmotic flow [EOF]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N22/00—Investigating or analysing materials by the use of microwaves or radio waves, i.e. electromagnetic waves with a wavelength of one millimetre or more
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15917599P | 1999-10-13 | 1999-10-13 | |
US60/159,175 | 1999-10-13 | ||
US19170200P | 2000-03-23 | 2000-03-23 | |
US60/191,702 | 2000-03-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN1425133A true CN1425133A (zh) | 2003-06-18 |
Family
ID=26855720
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN00817005A Pending CN1425133A (zh) | 1999-10-13 | 2000-10-13 | 检测和识别试样中分子事件的系统和方法 |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1224453A2 (ja) |
JP (1) | JP2003535310A (ja) |
KR (1) | KR20020071853A (ja) |
CN (1) | CN1425133A (ja) |
AU (3) | AU8023500A (ja) |
CA (1) | CA2386193A1 (ja) |
IL (1) | IL149001A0 (ja) |
MX (1) | MXPA02003815A (ja) |
NO (1) | NO20021687L (ja) |
WO (1) | WO2001027610A2 (ja) |
Cited By (17)
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---|---|---|---|---|
CN1914498B (zh) * | 2003-12-04 | 2012-01-04 | 麦克罗威斯克有限公司 | 流体探针 |
CN101849174B (zh) * | 2007-08-11 | 2013-05-29 | 麦克罗威斯克有限公司 | 流体探测器 |
CN101617209B (zh) * | 2006-03-16 | 2013-10-02 | 麦克罗威斯克有限公司 | 流体探针 |
TWI569017B (zh) * | 2014-11-14 | 2017-02-01 | Nippon Mektron Kk | Coaxial probe holding mechanism and electrical characteristics check device |
CN108257052A (zh) * | 2018-01-16 | 2018-07-06 | 中南大学 | 一种在线学生知识评估方法及其系统 |
CN108602065A (zh) * | 2015-12-23 | 2018-09-28 | 维京遗传学Fmba | 用于低温吸管的rfid识别系统 |
CN109192250A (zh) * | 2018-08-01 | 2019-01-11 | 华东理工大学 | 一种多相催化中克服表面物种快速迁移的加速模拟方法 |
JP2020098202A (ja) * | 2013-03-15 | 2020-06-25 | イナノベイト, インコーポレイテッド | アッセイシステムおよびカートリッジデバイス |
CN111500680A (zh) * | 2013-06-25 | 2020-08-07 | 普罗格诺西斯生物科学公司 | 检测样品中生物靶标的空间分布的方法和系统 |
CN115598464A (zh) * | 2022-10-08 | 2023-01-13 | 金华乐馨发制品有限公司(Cn) | 一种电缆末端高低压电路的检测和修复装置及其方法 |
US11733238B2 (en) | 2010-04-05 | 2023-08-22 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
US11732292B2 (en) | 2010-04-05 | 2023-08-22 | Prognosys Biosciences, Inc. | Spatially encoded biological assays correlating target nucleic acid to tissue section location |
US11739372B2 (en) | 2015-04-10 | 2023-08-29 | Spatial Transcriptomics Ab | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
US11788122B2 (en) | 2011-04-13 | 2023-10-17 | 10X Genomics Sweden Ab | Methods of detecting analytes |
US11866767B2 (en) | 2020-05-22 | 2024-01-09 | 10X Genomics, Inc. | Simultaneous spatio-temporal measurement of gene expression and cellular activity |
US12031177B1 (en) | 2020-06-04 | 2024-07-09 | 10X Genomics, Inc. | Methods of enhancing spatial resolution of transcripts |
USRE50065E1 (en) | 2012-10-17 | 2024-07-30 | 10X Genomics Sweden Ab | Methods and product for optimising localised or spatial detection of gene expression in a tissue sample |
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US6586946B2 (en) * | 2000-11-13 | 2003-07-01 | Signature Bioscience, Inc. | System and method for detecting and identifying molecular events in a test sample using a resonant test structure |
WO2002066983A2 (en) * | 2001-02-01 | 2002-08-29 | Signature Bioscience, Inc. | Bioassay device for detecting molecular events |
US20020168659A1 (en) * | 2001-02-12 | 2002-11-14 | Signature Bioscience Inc. | System and method for characterizing the permittivity of molecular events |
GB0117715D0 (en) * | 2001-07-19 | 2001-09-12 | Mrbp Res Ltd | Microwave biochemical analysis |
EP1417474B1 (en) * | 2001-07-25 | 2021-12-29 | The Trustees Of Princeton University | Nanochannel arrays and their preparation and use for high throughput macromolecular analysis |
US9678038B2 (en) | 2001-07-25 | 2017-06-13 | The Trustees Of Princeton University | Nanochannel arrays and their preparation and use for high throughput macromolecular analysis |
US20030032000A1 (en) * | 2001-08-13 | 2003-02-13 | Signature Bioscience Inc. | Method for analyzing cellular events |
KR100537504B1 (ko) | 2003-01-20 | 2005-12-19 | 삼성전자주식회사 | 생물학적 시료 내에서의 단백질 검출을 위한 자동화된 유동 시스템 |
US10746680B2 (en) * | 2006-11-16 | 2020-08-18 | General Electric Company | Sensing system and method |
CN101765462B (zh) | 2007-03-28 | 2013-06-05 | 博纳基因技术有限公司 | 使用纳米通道阵列的大分子分析方法 |
US9951386B2 (en) | 2014-06-26 | 2018-04-24 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US10323279B2 (en) | 2012-08-14 | 2019-06-18 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US10584381B2 (en) | 2012-08-14 | 2020-03-10 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US10752949B2 (en) | 2012-08-14 | 2020-08-25 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US9701998B2 (en) | 2012-12-14 | 2017-07-11 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US10273541B2 (en) | 2012-08-14 | 2019-04-30 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US10221442B2 (en) | 2012-08-14 | 2019-03-05 | 10X Genomics, Inc. | Compositions and methods for sample processing |
US20140155295A1 (en) | 2012-08-14 | 2014-06-05 | 10X Technologies, Inc. | Capsule array devices and methods of use |
US11591637B2 (en) | 2012-08-14 | 2023-02-28 | 10X Genomics, Inc. | Compositions and methods for sample processing |
GB201219016D0 (en) * | 2012-10-23 | 2012-12-05 | Liverpool John Moores University | Electromagnetic wave sensing |
WO2014093676A1 (en) | 2012-12-14 | 2014-06-19 | 10X Technologies, Inc. | Methods and systems for processing polynucleotides |
US10533221B2 (en) | 2012-12-14 | 2020-01-14 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
US9791453B2 (en) * | 2012-12-26 | 2017-10-17 | International Business Machines Corporation | Methods for determining binding capability of target ligands with G protein-coupled receptors using translocation through nanochannels |
CN108753766A (zh) | 2013-02-08 | 2018-11-06 | 10X基因组学有限公司 | 多核苷酸条形码生成 |
US10024851B2 (en) | 2013-10-15 | 2018-07-17 | International Business Machines Corporation | Use of disulfide bonds to form a reversible and reusable coating for nanofluidic devices |
US9255321B2 (en) | 2013-10-15 | 2016-02-09 | Globalfoundries Inc. | Directed surface functionalization on selected surface areas of topographical features with nanometer resolution |
US9303310B2 (en) | 2013-10-15 | 2016-04-05 | International Business Machines Corporation | Nanofluidic sensor comprising spatially separated functional sensing components |
CN110548550B (zh) | 2014-04-10 | 2022-03-08 | 10X基因组学有限公司 | 用于封装和分割试剂的流体装置、系统和方法及其应用 |
US9921181B2 (en) | 2014-06-26 | 2018-03-20 | International Business Machines Corporation | Detection of translocation events using graphene-based nanopore assemblies |
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AU2015339148B2 (en) | 2014-10-29 | 2022-03-10 | 10X Genomics, Inc. | Methods and compositions for targeted nucleic acid sequencing |
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Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0519250A3 (en) * | 1991-06-10 | 1993-06-02 | Miles Inc. | Microparticle-labeled binding assay analyzed by microwave spectroscopy |
GB2296571B (en) * | 1993-07-26 | 1998-02-11 | Phase Dynamics Inc | System and method for monitoring substances and reactions |
SE9700828D0 (sv) * | 1997-03-07 | 1997-03-07 | Asea Brown Boveri | Förfarande och anordning för att bestämma ett flertal kvalitetsparametrar vilka beskriver tillståndet hos ett organiskt material |
KR20010040559A (ko) * | 1998-02-02 | 2001-05-15 | 시그나츄어 바이오사이언스 인코포레이티드 | 분자 결합 이벤트의 검출용 방법 및 장치 |
-
2000
- 2000-10-13 KR KR1020027004757A patent/KR20020071853A/ko not_active Application Discontinuation
- 2000-10-13 IL IL14900100A patent/IL149001A0/xx unknown
- 2000-10-13 CA CA002386193A patent/CA2386193A1/en not_active Abandoned
- 2000-10-13 AU AU80235/00A patent/AU8023500A/en not_active Abandoned
- 2000-10-13 WO PCT/US2000/028491 patent/WO2001027610A2/en active Application Filing
- 2000-10-13 CN CN00817005A patent/CN1425133A/zh active Pending
- 2000-10-13 JP JP2001530570A patent/JP2003535310A/ja active Pending
- 2000-10-13 EP EP00970920A patent/EP1224453A2/en not_active Withdrawn
- 2000-10-13 MX MXPA02003815A patent/MXPA02003815A/es unknown
-
2002
- 2002-04-10 NO NO20021687A patent/NO20021687L/no not_active Application Discontinuation
-
2005
- 2005-08-19 AU AU2005203756A patent/AU2005203756A1/en not_active Abandoned
-
2008
- 2008-07-14 AU AU2008203111A patent/AU2008203111A1/en not_active Abandoned
Cited By (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102269686B (zh) * | 2003-12-04 | 2015-05-06 | 麦克罗威斯克有限公司 | 流体探针 |
CN1914498B (zh) * | 2003-12-04 | 2012-01-04 | 麦克罗威斯克有限公司 | 流体探针 |
CN101617209B (zh) * | 2006-03-16 | 2013-10-02 | 麦克罗威斯克有限公司 | 流体探针 |
CN102269687B (zh) * | 2006-03-16 | 2014-11-05 | 麦克罗威斯克有限公司 | 流体探针 |
CN101849174B (zh) * | 2007-08-11 | 2013-05-29 | 麦克罗威斯克有限公司 | 流体探测器 |
US11733238B2 (en) | 2010-04-05 | 2023-08-22 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
US11866770B2 (en) | 2010-04-05 | 2024-01-09 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
US11767550B2 (en) | 2010-04-05 | 2023-09-26 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
US11761030B2 (en) | 2010-04-05 | 2023-09-19 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
US11732292B2 (en) | 2010-04-05 | 2023-08-22 | Prognosys Biosciences, Inc. | Spatially encoded biological assays correlating target nucleic acid to tissue section location |
US11795498B2 (en) | 2011-04-13 | 2023-10-24 | 10X Genomics Sweden Ab | Methods of detecting analytes |
US11788122B2 (en) | 2011-04-13 | 2023-10-17 | 10X Genomics Sweden Ab | Methods of detecting analytes |
USRE50065E1 (en) | 2012-10-17 | 2024-07-30 | 10X Genomics Sweden Ab | Methods and product for optimising localised or spatial detection of gene expression in a tissue sample |
JP2020098202A (ja) * | 2013-03-15 | 2020-06-25 | イナノベイト, インコーポレイテッド | アッセイシステムおよびカートリッジデバイス |
CN111500680B (zh) * | 2013-06-25 | 2024-04-16 | 普罗格诺西斯生物科学公司 | 检测样品中生物靶标的空间分布的方法和系统 |
CN111500680A (zh) * | 2013-06-25 | 2020-08-07 | 普罗格诺西斯生物科学公司 | 检测样品中生物靶标的空间分布的方法和系统 |
US11821024B2 (en) | 2013-06-25 | 2023-11-21 | Prognosys Biosciences, Inc. | Methods and systems for determining spatial patterns of biological targets in a sample |
US11753674B2 (en) | 2013-06-25 | 2023-09-12 | Prognosys Biosciences, Inc. | Methods and systems for determining spatial patterns of biological targets in a sample |
TWI569017B (zh) * | 2014-11-14 | 2017-02-01 | Nippon Mektron Kk | Coaxial probe holding mechanism and electrical characteristics check device |
US11739372B2 (en) | 2015-04-10 | 2023-08-29 | Spatial Transcriptomics Ab | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
CN108602065A (zh) * | 2015-12-23 | 2018-09-28 | 维京遗传学Fmba | 用于低温吸管的rfid识别系统 |
CN108257052A (zh) * | 2018-01-16 | 2018-07-06 | 中南大学 | 一种在线学生知识评估方法及其系统 |
CN108257052B (zh) * | 2018-01-16 | 2022-04-22 | 中南大学 | 一种在线学生知识评估方法及其系统 |
CN109192250A (zh) * | 2018-08-01 | 2019-01-11 | 华东理工大学 | 一种多相催化中克服表面物种快速迁移的加速模拟方法 |
CN109192250B (zh) * | 2018-08-01 | 2021-12-07 | 华东理工大学 | 一种多相催化中克服表面物种快速迁移的加速模拟方法 |
US11866767B2 (en) | 2020-05-22 | 2024-01-09 | 10X Genomics, Inc. | Simultaneous spatio-temporal measurement of gene expression and cellular activity |
US12031177B1 (en) | 2020-06-04 | 2024-07-09 | 10X Genomics, Inc. | Methods of enhancing spatial resolution of transcripts |
CN115598464A (zh) * | 2022-10-08 | 2023-01-13 | 金华乐馨发制品有限公司(Cn) | 一种电缆末端高低压电路的检测和修复装置及其方法 |
Also Published As
Publication number | Publication date |
---|---|
KR20020071853A (ko) | 2002-09-13 |
NO20021687L (no) | 2002-06-12 |
MXPA02003815A (es) | 2002-09-30 |
EP1224453A2 (en) | 2002-07-24 |
WO2001027610A2 (en) | 2001-04-19 |
AU2008203111A1 (en) | 2008-08-07 |
AU2005203756A1 (en) | 2005-09-15 |
JP2003535310A (ja) | 2003-11-25 |
IL149001A0 (en) | 2002-11-10 |
WO2001027610A3 (en) | 2002-03-28 |
NO20021687D0 (no) | 2002-04-10 |
WO2001027610A9 (en) | 2002-08-01 |
AU8023500A (en) | 2001-04-23 |
CA2386193A1 (en) | 2001-04-19 |
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