CN1399887A - Guanidine alcohol composite multifunctional hand-cleaning disinfectant - Google Patents
Guanidine alcohol composite multifunctional hand-cleaning disinfectant Download PDFInfo
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- CN1399887A CN1399887A CN 01115168 CN01115168A CN1399887A CN 1399887 A CN1399887 A CN 1399887A CN 01115168 CN01115168 CN 01115168 CN 01115168 A CN01115168 A CN 01115168A CN 1399887 A CN1399887 A CN 1399887A
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- isopropyl alcohol
- ethanol
- hand
- guanidine
- oxireme
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Abstract
The composition of hand-cleaning special disinfectant contains (wt%) oxirene carboxyl guanidine 13-26.5, ethyl alcohol 34-56, isopropanol 10.5-15.5, polyvinyl acid 0.25-1.0, triethanolamine 0.5-1.5, methyl glucoside-20 0.6-1.0, propanetriol 0.2-1.0 vitamin E 0.2-0.5 and purified water adding to 100. It is non-toxic, colourless, smellless, non-irritative, non-corrosive, pollutionless, high-effective, low in concentration, good in stability, convenient for carrying about, has no need of washing unit water, can be used for disinfecting hand surface and protecting skin for various people. Said invention also provides its preparation method.
Description
Professional disinfectant, the especially active ingredient that the present invention relates to a kind of hand is oxireme carboxy guanidine alcohols hand-cleaning disinfectant and preparation method thereof.Be used for the sterilizing and the skin care of various occasions, every field, various age people's mucocutaneous, body surface hand.
The professional disinfectant kind of existing hand is a lot, and bactericidal property differs, and the branch of high, medium and low effect is arranged.The valid density of high effect disinfectants is also high often, and cost price is also high.And existing disinfectant poor stability, toxic, corrosivity and penetrating odor, adversary's skin has certain damage, and environment is also had certain pollution, and the hand after the sterilization also needs a large amount of water flushings.Therefore, people to wish to have a kind of be sterilizing skin-protective safety and stability and need not the composite multifunction disinfectant of the professional hand of water again always.
The object of the present invention is to provide a kind of professional disinfectant that can overcome the hand of existing procucts deficiency, belong to the free of contamination food grade products of nontoxic, colourless, tasteless, non-stimulated, no burn into, have efficient, low concentration, good stability, need not the water flushing, easy to carry, characteristics that the sterilizing skin-protective function is many.
Main points of the present invention are to select suitable component, and rationally are mixed, and form a kind of oxireme carboxy guanidine alcohols hand-cleaning disinfectant through emulsion reaction.
The prescription following (component and percentage by weight % thereof) that the present invention selects: oxireme carboxy guanidine 13-26.5 ethanol 34-56 isopropyl alcohol 10.5-15.5 polyacrylic acid 0.25-1.0 triethanolamine 0.5-1.5 methyl glucoside-20 0.6-1.0 glycerine 0.2-1.0 vitamin E 0.2-0.5 purified water adds to 100
The oxireme carboxy guanidine is as main sterilization component, guanidine radicals in this component has very high activity in polymerisation, make polymeric derivative be electropositive, so be easy to be usually electronegative each bacterioid, viral adsorbed, thereby suppressed the splitting function of bacterium, virus, made bacterium, the virus lose reproductive function, in addition the film that forms of polymer, stopped up the respiration channel of microorganism, microorganism is choked to death.
Ethanol and isopropyl alcohol add in the mixture as main sterilization component solvent, combine with the solute that contains aerobic nitrogen by hydrogen bond, and polymer is easier to and each bacterioid, virus absorption.Its mechanism of action is the concurrent disinfection of ethanol and isopropyl alcohol, has extremely strong sex change dehydration, and the space that pure molecule enters protein peptide chain makes mycoprotein sex change or precipitation.Alcohols can disturb the metabolism of microorganism simultaneously, has suppressed bacterium and has bred fast.Alcohols can make the cell wall lysis of bacterial virus, and pure molecule enters endochylema rapidly, and breathing and the enzyme system of bacterium are destroyed, and makes bacterium and virus dead at once, thereby has played extremely strong bactericidal action.The volatility of ethanol and isopropyl alcohol is extremely strong, makes after can hand-washing dry and comfortable rapidly.
Polyacrylic acid, triethanolamine, add in the mixture in proportion, purpose is by its characteristic, the viscosity of thimerosal is improved be the colloid shape, and very fast surface at hand forms one deck colourless transparent film, has increased long-term fungistatic effect.
Glycerine, vitamin E, methyl glucoside, add in the mixture in proportion, purpose is by its characteristic skin to be had to nourish and moisture-keeping function.
The preparation method of product of the present invention is:
(1) by proportioning described component is mixed program of reaction in the emulsion reaction jar except that ethanol, isopropyl alcohol.
(2) packing after question response liquid cooling to 30～40 ℃ adding ethanol, isopropyl alcohol dissolving are mixed.
The present invention compares with existing hand disinfectant has advantage: (1) sterilization and disinfection effect is remarkable, and through experiment, this product is to Escherichia coli, staphylococcus aureus, Candida albicans, bacillus subtilis black variety bud cell, and 1 minute, sterilizing rate can reach 100%; To virus, be role of delegate 2 minutes with the hepatitis type B virus, sterilizing rate can reach 100%.(2) nontoxic, colourless, tasteless, non-stimulated, non-corrosiveness.Contained after measured various Toxics all are lower than the physics and chemistry health national standard of limiting the quantity of.To the animal toxicology experiment, do not produce adverse consequences.Belong to nontoxic food-grade disinfectant.Be suitable for the sterilizing and the skin care of various occasions, every field, various age people's mucocutaneous, body surface hand.(3) this product is big molecular glue shaped polymer, and chemical property is very stable, after testing, in 54 ℃ of two week, active ingredient rate of descent＜3%, 37 ℃, 3 months active ingredient rate of descent＜4%, room temperature was placed 1 year, and active ingredient descends＜6%.(4) need not water flushing, easy to carry.(5) technology is simple, and cost is low.
The present invention is described in further detail below in conjunction with embodiment:
According to different occasions, different fields, all ages and classes Person's skin mucous membrane, the sterilizing of body surface hand and skin care requirement are configured according to following table institute column data (percentage by weight %) and described step thereof: tables of data: prescription one: oxireme carboxy guanidine 25-25.5 ethanol 45-55.5 isopropyl alcohol 13.5-15.5 polyacrylic acid 0.5-1.0 triethanolamine 0.5-1.0 methyl glucoside-20 0.5-1.0 glycerine 0.5-1.0 vitamin E 0.25-0.5 purified water adds to 100 prescriptions two: oxireme carboxy guanidine 20-21.5 ethanol 35-45.5 isopropyl alcohol 11.5-13.5 polyacrylic acid 0.2-0.5 triethanolamine 0.2-0.5 methyl glucoside-20 0.5-0.8 glycerine 0.2-0.6 vitamin E 0.25-0.5 purified water adds to 100 prescriptions three: oxireme carboxy guanidine 25-26.5 ethanol 34-48.5 isopropyl alcohol 10.5-14.5 polyacrylic acid 0.1-0.5 triethanolamine 0.1-0.5 methyl glucoside-20 0.6-0.8 glycerine 0.5-0.7 vitamin E 0.2-0.5 purified water adds to 100 prescriptions four: oxireme carboxy guanidine 13-13.5 ethanol 55-56 isopropyl alcohol 10.5-11.0 polyacrylic acid 0.3-0.8 triethanolamine 1.0-1.5 methyl glucoside-20 0.5-0.8 glycerine 0.4-0.8 vitamin E 0.2-0.3 purified water adds to 100
Claims (2)
1, a kind of with the oxireme carboxy guanidine, ethanol and isopropyl alcohol are as the hand specialty disinfecting skin-care agent of main sterilizing component, and it is characterized in that having following prescription (component and percentage by weight % thereof): oxireme carboxy guanidine 13-26.5 ethanol 34-56 isopropyl alcohol 10.5-15.5 polyacrylic acid 0.25-1.0 triethanolamine 0.5-1.5 methyl glucoside-20 0.6-1.0 glycerine 0.2-1.0 vitamin E 0.2-0.5 purified water adds to 100
2, the preparation method of the described hand specialty of a kind of claim 1 disinfecting skin-care disinfectant is characterized in that having following step:
(1) by proportioning described component is mixed program of reaction in the emulsion reaction jar except that ethanol, isopropyl alcohol;
(2) behind question response liquid cooling to 30～40 ℃, add ethanol, isopropyl alcohol dissolving back packing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01115168 CN1399887A (en) | 2001-07-26 | 2001-07-26 | Guanidine alcohol composite multifunctional hand-cleaning disinfectant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01115168 CN1399887A (en) | 2001-07-26 | 2001-07-26 | Guanidine alcohol composite multifunctional hand-cleaning disinfectant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1399887A true CN1399887A (en) | 2003-03-05 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 01115168 Pending CN1399887A (en) | 2001-07-26 | 2001-07-26 | Guanidine alcohol composite multifunctional hand-cleaning disinfectant |
Country Status (1)
| Country | Link |
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| CN (1) | CN1399887A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213419A (en) * | 2014-05-31 | 2016-01-06 | 尹连花 | A kind of composite multifunctional hand-cleaning disinfectant |
| CN105769592A (en) * | 2016-05-20 | 2016-07-20 | 蔡华英 | Sterilizing hand detergent |
| CN105997961A (en) * | 2016-07-21 | 2016-10-12 | 南通东华服装有限公司 | Multifunctional antibacterial hand-cleaning sanitizer |
| CN106172396A (en) * | 2016-07-21 | 2016-12-07 | 南通佰能油化有限公司 | Multifunctional hand-cleaning disinfectant |
| CN108042562A (en) * | 2017-12-22 | 2018-05-18 | 北京长江脉医药科技有限责任公司 | Disposable disinfectant of the compound alcohol of gel-type and preparation method thereof |
-
2001
- 2001-07-26 CN CN 01115168 patent/CN1399887A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213419A (en) * | 2014-05-31 | 2016-01-06 | 尹连花 | A kind of composite multifunctional hand-cleaning disinfectant |
| CN105769592A (en) * | 2016-05-20 | 2016-07-20 | 蔡华英 | Sterilizing hand detergent |
| CN105997961A (en) * | 2016-07-21 | 2016-10-12 | 南通东华服装有限公司 | Multifunctional antibacterial hand-cleaning sanitizer |
| CN106172396A (en) * | 2016-07-21 | 2016-12-07 | 南通佰能油化有限公司 | Multifunctional hand-cleaning disinfectant |
| CN108042562A (en) * | 2017-12-22 | 2018-05-18 | 北京长江脉医药科技有限责任公司 | Disposable disinfectant of the compound alcohol of gel-type and preparation method thereof |
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Addressee: Li Menggang Document name: Notice of publication of application for patent for invention |
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