JP2022014096A - Coldness imparting antibacterial deodorant - Google Patents

Abstract

To provide a coldness imparting antibacterial deodorant that gives mild coldness, has no flammability and exhibits high antibacterial and deodorizing effect.SOLUTION: A coldness imparting antibacterial deodorant contains menthol and calcium oxide solution or calcium hydroxide solution and also contains carrageenan.SELECTED DRAWING: None

Description

The present invention relates to a composition that is inexpensive, highly safe, has a cooling sensation effect, and has high antibacterial and deodorant properties.

In recent years, with the activity of industrial activities, the concentration in the atmosphere has increased due to the large emission of greenhouse gases such as carbon dioxide, methane, and chlorofluorocarbons, and the absorption of heat has increased. As a result, the temperature has begun to rise significantly. ..

This is a phenomenon of global warming, and the temperature in summer has become extremely high and severe in recent years. On the other hand, it is recommended to set the air conditioner temperature higher from the viewpoint of protecting the global environment. Also, in the hot season, Cool Biz without a jacket or tie is taken in, but there are cases where it is not possible to wear light clothing, so future measures against heat are a major issue to be considered.

As a product that suppresses such heat, a product that temporarily surpasses the heat by locally imparting a cooling sensation (Patent Document 1: Japanese Patent Application Laid-Open No. 2000-239142). Further, there is known a cooling sensation-imparting agent for clothing, which is applied to clothing and imparts a cooling sensation by coming into contact with the body (Patent Document 2: Japanese Patent Application Laid-Open No. 2010-84269).

However, since cooling sprays, cooling sprays, etc. are usually sprayed directly on the skin or sprayed on clothing, some people are sensitive to the components contained in them, especially alcohol and ethanol, causing skin problems such as rough skin. There was a problem such as. Further, when a volatile cooling component is used, there is a problem that the cooling sensation is not maintained because the cooling component is always volatilized at body temperature.

In order to enhance the cooling effect and cooling effect, there is a tendency to increase the mixing ratio of alcohol, ethanol and L-menthol, which makes the cooling effect too strong and feels cold, and the unique odor of L-menthol is too strong. I sometimes felt uncomfortable.

In addition, the antibacterial disinfecting effect of the blended alcohol, ethanol and L-menthol also has high performance, and the alcohol (ethanol) used as a raw material for pharmaceuticals is intended to prevent it from being diverted to drinking. , A certain amount of chemical substances of the standard set by the Ministry of Economy, Trade and Industry can be purchased at a special price (exemption from the amount equivalent to liquor tax) by mixing it with alcohol. For this reason, alcohol (ethanol) is used as a disinfectant for external use, and it has been proved that it is highly effective as a solvent.

However, on the other hand, when a product containing alcohol or ethanol is used frequently, rough skin or rough hands may occur, and there is a great concern about the risk of flammability due to alcohol or ethanol.

From such a background, the present invention has been made in view of the above points, is inexpensive, has a cooling sensation effect, is effective against a wide range of microorganisms, viruses, etc., and is not highly irritating when used, and has a feeling of use. We provide a cooling sensation antibacterial deodorant that can be added with a moisturizer while there is a strong demand for the development of products that are not disgusting, prevent rough skin and rough hands when used, and are friendly to the body and the environment. The purpose is to do.

In addition, there is a demand to extend the period of cooling sensation. There is also a demand for a longer lasting effect of sterilization.

JP 2000-239142 JP-A-2010-84269

Therefore, the present invention provides a cooling sensation-imparting antibacterial deodorant having a gentle cooling sensation effect, non-flammability, and a high antibacterial deodorizing effect, and further has a longer duration of cooling sensation. The main purpose is to provide a cooling sensation-imparting antibacterial disinfectant that can enhance the effect of sterilization and disinfection.

As a result of diligent studies to solve the above problems, the present inventors have made the following first liquid component into a second liquid by adding alkaline ionized water, and further added other liquid components to the above problems. Was resolved.

<1st liquid component (manufacturing method)>
Propylene glycol (PG) is used instead of the alcohol or ethanol used in the composition of L-menthol dissolved in alcohol or ethanol that exerts an antibacterial deodorant effect. Further, calcium oxide obtained by high-temperature firing calcium carbonate derived from living organisms or calcium derived from minerals, or an aqueous solution obtained by hydrating calcium hydroxide obtained by adding water to the calcium oxide. In addition, purified water, clean water or alkaline ionized water (alkaline (PH 9 to 13.0) produced using an alkaline ionized water device) in an aqueous solution obtained by hydrating calcium hydroxide obtained by adding water to calcium oxide. An aqueous solution characterized by being diluted with electrolyzed water and blended. Further, in the first liquid of the present invention, eggshell, which is calcium carbonate derived from an organism, was used.

Further, the calcium oxide aqueous solution or the calcium hydroxide aqueous solution is prepared by dissolving L-menthol or an L-menthol solution in which propylene glycol is used instead of alcohol (ethanol) for dissolving L-menthol oil, which exerts a cooling sensation effect. In addition, electrolyzation of purified water, clean water or alkaline ionized water (alkaline (ph9 to 13.0) produced using an alkaline ionized water device) in an aqueous solution obtained by hydrating calcium hydroxide obtained by adding water to calcium oxide. Obtained by diluting with water and mixing the blended solutions.

However, the calcium oxide and calcium hydroxide aqueous solutions have a property of being strongly basic. Due to its strong basic effect, it exerts an antibacterial deodorant effect, but because the L-menthol to be mixed is in the neutral region, it is a mixture of calcium oxide and calcium hydroxide aqueous solution and an L-menthol solution dissolved with propylene glycol. Although there was a problem with the ratio, the first solution of the present invention was completed as a result of further research based on various findings.

The first liquid of the present invention, a cooling sensation-imparting antibacterial deodorant, can feel a cooling sensation and stay cool even on a hot day just by spraying it directly on the skin. In addition, the composition of the first liquid of the present invention can be used for sensitive skin because it is less irritating, and there is very little concern about rough skin, so that it can be used repeatedly as many times as necessary. In addition, since it has a high antibacterial and deodorant effect, it can also be used as a disinfectant solution.

Furthermore, the first liquid antibacterial deodorant of the present invention can be used by people who cannot disinfect with alcohol because it does not use alcohol (ethanol), and it is not flammable and highly safe. An antibacterial deodorant that imparts a feeling of coldness can be obtained.

The cooling sensation-imparting antibacterial deodorant of the first liquid of the present invention is an aqueous solution obtained by hydrating L-menthol, propylene glycol, calcium oxide, or calcium hydroxide. In addition, electrolyzation of purified water, clean water or alkaline ionized water (alkaline (ph9 to 13.0) produced using an alkaline ionized water device) in an aqueous solution obtained by hydrating calcium hydroxide obtained by adding water to calcium oxide. It is characterized in that it is obtained by mixing a liquid that has been diluted with water and mixed.

As used herein, the term "cooling sensation" means that the portion of the first liquid of the present invention in which the antibacterial deodorant for imparting a cooling sensation is directly sprayed and applied to the skin has a weak and cool feeling. Furthermore, since alcohol (ethanol) is not used, there is very little concern about rough skin. The composition of the first liquid of the present invention is described for each component.

(1) Menthol As the menthol used in the composition of the first liquid of the present invention, isolated L-menthol, d menthol, dl menthol, mint brain (mint crystal) and the like can be used, and it is preferable. L-menthol. Further, in the first liquid of the present invention, it is also possible to use an essential oil containing L-menthol. Examples of such essential oils include peppermint oil, spearmint oil, peppermint oil, eucalyptus oil and the like. These essential oils can also be used as the menthol component of the first liquid cooling sensation imparting agent of the present invention, but from the viewpoint of suppressing stickiness when applied to clothing and odor caused by impurities contained in the essential oil. , It is preferable to use isolated menthol. In the composition of the first liquid of the present invention, these compounds and essential oils can be used alone or in combination of two or more as menthol.

The blending ratio of menthol in the composition of the first liquid of the present invention is about 0.1% by weight or more from the viewpoint of cooling sensation because a strongly basic calcium oxide aqueous solution or calcium hydroxide aqueous solution is mixed. All you need is. However, if it is more than about 25% by weight, there is a problem that the irritation to the skin is too strong, so it is preferably about 25% by weight or less.
At present, many people prefer hypoallergenicity, so the cooling sensation is preferably about 0.1 to 3.0% by weight, more preferably about 0.1 to 1.5% by weight, and most preferably 0. It is about 1 to 1.0% by weight. In addition, the blending ratio of menthol may generate an offensive odor as the blending ratio concentration of menthol increases due to mixing with a strongly basic calcium oxide aqueous solution or calcium hydroxide aqueous solution. Therefore, it is necessary to have at least about 0.1 to 3.0% by weight.
Here, if the proportion of menthol is high, the cooling sensation imparting effect is high (the antibacterial deodorizing action is low), and conversely, if the proportion of the calcium oxide aqueous solution or the calcium hydroxide aqueous solution is high, the antibacterial deodorizing action is enhanced (the antibacterial deodorizing action is high). The cooling effect is low.)
After comparing and examining the ratios of the two and examining multiple examples, it was concluded that the above ratios are appropriate.
To restate, since many people prefer hypoallergenicity, the cooling sensation action is preferably about 0.1 to 3.0% by weight, more preferably about 0.1 to 1.5% by weight, and most preferably 0. It is about 1 to 1.0% by weight.

(2) Calcium oxide aqueous solution or calcium hydroxide aqueous solution The calcium oxide aqueous solution and the calcium hydroxide aqueous solution used in the composition of the first liquid of the present invention can be obtained from biological calcium carbonate or mineral-derived calcium carbonate. It consists of calcium oxide or calcium hydroxide.

The concentration of the calcium oxide obtained by firing each calcium carbonate at a high temperature (850 ° C. or higher) or the aqueous solution of calcium hydroxide obtained by adding water to the calcium oxide is preferably about 0.1% or more. Further, from the viewpoint of antibacterial and deodorant properties, it is more preferably about 0.1 to 7.0%, and most preferably about 0.15 to 2.0%.
Originally, the calcium has a low hydration property, but when the amount of the calcium added to water is large, the pH value becomes relatively high and the pH value becomes long-lasting.
However, if the compounding concentration is too high, the white turbidity of the aqueous solution is too strong and it takes too much time for filtration, so the above value is most preferable.

(3) Propylene glycol Propylene glycol used in the composition of the first liquid of the present invention is a colorless, odorless, slightly viscous liquid and has excellent properties as a solvent, so that it completely dissolves water. It has the property of dissolving well in organic compounds. In addition, it has very low toxicity and is almost harmless to the human body. It also has a good moisturizing and moisturizing effect. In the first liquid of the present invention, (1) it is used as a solvent for menthol, but when the amount is large, the following values are preferable from the viewpoint of moisturizing action and moisturizing action, in view of stickiness to the skin and the like. (1) From the viewpoint of a solvent, it is preferably about 15.0% by weight or more with respect to 1% by weight of menthol. Further, from the viewpoint of dissolution stability, it is more preferably about 20.0 to 40.0% by weight, and most preferably about 25.0 to 35.0% by weight.

(3) Other components The cooling sensation-imparting antibacterial deodorant of the first liquid of the present invention can be diluted with purified water or clean water with respect to the above-mentioned menthol and calcium oxide aqueous solution or calcium hydroxide aqueous solution. .. When purified water is contained, the content is about 0 to 97.0% by weight, preferably about 0 to 95.0% by weight, more preferably about 0 to 90.0% by weight, based on the total amount of the composition. Further, glycerin may be contained in consideration of moisturizing property. When glycerin is contained, it is about 0 to 5.0% by weight, preferably about 0 to 3.0% by weight, more preferably about 0 to 2.0% by weight, based on the total amount of the composition. The cooling sensation-imparting antibacterial deodorant of the first liquid of the present invention can be obtained by mixing a predetermined amount of each of the above components. The mixing method is not particularly limited, and a conventionally known method is adopted.

The first liquid antibacterial deodorant of the present invention thus obtained is not particularly limited as long as it is a dosage form that can be directly sprayed onto the skin, and can be appropriately prepared according to a conventionally known method. Examples of the dosage form of the first liquid cooling sensation-imparting agent for clothing of the present invention include a mist spray type, a roll-on type, a pump spray type, etc. Then, it is preferable that it is a mist spray type.

When the composition of the first liquid of the present invention is used, an appropriate amount may be sprayed directly on the skin. The specific spray amount is not particularly limited, for example, 0.25 to 1.5 ml / cm2, but is preferably several times (4 to 5 times) due to a slight cooling sensation effect. In addition, when sprayed on the armpits, nape of the neck, back, etc., where sweat is easy to sweat, the person feels cold when sweating, and the effect of the first liquid of the present invention can be more effectively exerted. More preferably, after several hours (1 to 3 hours), the spraying amount is not particularly limited, but 0.25 to 1.5 ml / cm2 is preferably sprayed several times (4 to 5 times). Further, in terms of antibacterial and deodorant properties, the calcium oxide aqueous solution or the calcium hydroxide aqueous solution has been found to be highly safe, and has a high effect on sweat odor (acetic acid odor).

Hereinafter, the first liquid of the present invention will be described in more detail with reference to examples, but the first liquid of the present invention is not limited thereto.

The prescription ratio of the antibacterial deodorant (first liquid) for imparting a cooling sensation shown in Table 1 below was 0.5% by weight of menthol, and 28% by weight of propylene glycol used for dissolution. 15 monitors for the presence or absence of a cooling sensation effect using a mixture of calcium hydroxide aqueous solution concentration 3.0% by 25% by weight, purified water by 70% by weight, and glycerin by 1.5% by weight (ages 20s and 30s; 7 women) And 8 men).

The evaluation was carried out by filling a mist spray bottle with a cooling sensation-imparting antibacterial deodorant and spraying it on each part of the arm, neck and foot 5 times (0.25 to 1.5 ml / cm2). The evaluation criteria are as follows. The results are shown in (1 below).
<Cooling effect>
1 I don't feel cold 2 I don't feel much cold 3 I feel a little cold 4 I feel cold 5 I feel a strong cold

(Table 1)
Evaluation of cold feeling 0 people who do not feel cold feeling 0 people who feel cold feeling 5 people who feel cold feeling 9 people who feel cold feeling strongly 1 person

Table 2 shows the results of an antibacterial test (test bacteria: Staphylococcus aureus) using the antibacterial deodorant that imparts a feeling of coldness with the first solution of the present invention.
(Table 2)
Antibacterial test sample Initial number of bacteria (number of viable bacteria (pieces / mL)) 6 hours (number of viable bacteria (pieces / mL))
This product has not been measured <1.0
Distilled water (control) 6.6E + 04 8.4E + 04
Test Bacteria: Staphylococcus aureus NBRC12732
Inspection agency: Kaken Test Center

Table 3 shows the results of a deodorant test using swill in the antibacterial deodorant that imparts a feeling of coldness by the first liquid of the present invention. The presence or absence of the deodorant effect was evaluated by 15 monitors (ages 20s and 30s; 7 females and 8 males).

The swill was sprayed with the antibacterial deodorant for imparting a cooling sensation by the first liquid of the present invention five times. The evaluation criteria are as follows. The results are shown in Table 3 below.

<Smell effect>
1 I don't feel the odor 2 I don't feel the odor so much 3 I feel the odor a little 4 I feel the odor 5 I feel the odor strongly

(Table 3)
Smell evaluation Rating 14 people who do not feel odor 1 person who does not feel odor so much 1 person who feels a little odor 0 people who feel odor 0 people who feel odor strongly 0 people

From the results of Tables 1 to 3, the cooling sensation-imparting antibacterial deodorant of the first liquid of the present invention is effective in cooling sensation action, antibacterial property, and deodorizing property.

<Liquid 2>
The following alkaline ionized water is added to the components of the first liquid described above to prepare the second liquid.
(2-2) Alkaline ionized water (electrolyzed hydrogen water, reduced hydrogen water, electrolytically reduced water, hydrogen-containing alkaline electrolytic water)
In the first liquid of the present invention, the aqueous solution of calcium oxide or calcium hydroxide that can be obtained from the above-mentioned biological calcium carbonate or mineral-derived calcium carbonate is re-precipitated by calcium due to cloudiness described above. The issue is calcification.

In order to reduce the remineralization phenomenon due to the precipitation of calcium, which is the problem, the remineralization phenomenon due to the precipitation of calcium is reduced by diluting the first liquid of the present invention with alkaline ionized water. It is possible. As the alkaline ionized water, alkaline (ph 9.0 to 13.0) electrolyzed water produced using an alkaline ionized water device is used.
The dilution ratio is preferably 1 for the first liquid of the present invention and 0.8 to 3.98 for alkaline ionized water (mass ratio).
More preferably, when the first liquid is 1, it is desirable that the alkaline ionized water is diluted at a ratio (mass ratio) of 1.58 to 2.5.
Here, if a large amount of alkaline ionized water is added, the remineralization phenomenon can be prevented, but on the other hand, the antibacterial deodorant action (cooling sensation action) is lowered.
On the contrary, when the amount of alkaline ionized water is small, the antibacterial deodorant effect is enhanced, but on the other hand, the possibility of remineralization is increased.
From the relationship of the trade-off between the two, it is judged that the above ratio is currently appropriate from multiple experimental examples.

<Other liquid components>
The first liquid (calcium oxide obtained by high-temperature firing calcium carbonate derived from living organisms or calcium derived from minerals, or an aqueous solution obtained by hydrating calcium hydroxide obtained by adding water to the calcium oxide is used in alkaline ionized water. Alkaline ionized water is added to the diluted aqueous solution) to dilute it (second solution), and the following components are further added to liquefy it into a gel.
(B) PG (prepyrene glycol)
(B) Carrageenan (C) Water

PG (prepyrene glycol) is about 8%, carrageenan is about 1.5%, and water is about 10.5% with respect to 80% of the first liquid of the present invention. The proportion of each component is variable.
Specifically, when the first liquid is diluted with electrolyzed water (second liquid) and the mass is compared with other liquid components (PG + water), the ratio of caraginan is 0.5 to 3%. It can be changed within the range (100% as a whole). It is judged that it can withstand practical use within this range.
If there is little carrageenan, the viscosity will be insufficient. On the other hand, if it is too high, the viscosity will be too high.
A range more appropriate than 1.5 to 3% is preferably 1.2 to 1.7%. Within this range, it has almost the same effect as the above-mentioned optimum component ratio.

As described above, the antibacterial disinfectant that imparts a cooling sensation, which is a mixture of the first liquid, PG, caraginan, and water, has an improved antibacterial effect. It becomes longer), and the time to feel cold can be improved.

As described above, the antibacterial disinfectant that imparts a cooling sensation, which is a mixture of the first liquid, PG, caraginan, and water, has an improved antibacterial effect. It becomes longer), and the time to feel cold can be improved.

Claims (4)

A cooling sensation-imparting antibacterial deodorant containing 0.1 to 3.0% by weight of menthol and an aqueous solution of calcium oxide or an aqueous solution of calcium hydroxide and containing caraginan. The antibacterial deodorant for imparting a cooling sensation according to claim 1, wherein the menthol is L-menthol. The antibacterial deodorant for imparting a cooling sensation according to claim 1 or 2, wherein the aqueous solution of calcium oxide or the aqueous solution of calcium hydroxide is diluted with alkaline ionized water. The antibacterial deodorant for imparting a cooling sensation according to any one of claims 1 to 3, which contains PG.