CN1398625A - Chinese medicine prepn for treating obliterans thromboangitis - Google Patents
Chinese medicine prepn for treating obliterans thromboangitis Download PDFInfo
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- CN1398625A CN1398625A CN02135295A CN02135295A CN1398625A CN 1398625 A CN1398625 A CN 1398625A CN 02135295 A CN02135295 A CN 02135295A CN 02135295 A CN02135295 A CN 02135295A CN 1398625 A CN1398625 A CN 1398625A
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Abstract
The Chinese medicine preparation for treating thromboangitis obliterans as chronic obliterative inflammation of peripheral blood vessel is prepared with ant, licorice, red sage, zedoary, angelica and other Chinese medicine as raw material. The medicine pwoder is obtained after crushing, soaking, decoration, filtering, concentration, alcohol extraction, mixing, grinding and technological steps. The medicine preparation of the present invention has unique recipe and high curative effect.
Description
Affiliated technical field
The present invention relates to a kind of Chinese medicine for the treatment of the chronic occlusion inflammation of peripheral vessels.
Background technology
Thromboangiitis obliterans is chronic general vascular disorder, is a kind of periodicity, segmental inflammatory disorders of artery and vein.Pathological changes is involved the medium and small arteriovenous of extremity, sees so that lower limb more more.Lumen of vessels takes place inaccessible, and the tube wall fibrosis causes the local organization ischemia, and last necrosis causes acral coming off.Motherland's medical science thinks that primary disease is sick mainly to be owing to feelings will internal injury, kidney liver deficiency, cold-damp are subjected to admittedly, so that cold-damp cohesion meridians outward, and the illness plug is obstructed, and vim and vigour running does not freely form.Cold stimulation is the key factor that primary disease takes place.Extremity are the end of all sun, get yang-energy and temperature.The place is cold for a long time, and the cold-evil compels outward, and yang-energy can not reach in four ends, causes the cold-evil and attacks channels deeply, and QI-blood circulation is not smooth, and blood is met cold coagulation, and the stasis of blood stagnates obstructed, stagnation of QI and blood may bring about pain.With the passing of time, limbs are just become homeless foster, cause gangrene.In addition, the generation of primary disease is also relevant with factors such as long-term smoking, wounds.Under the long-time stimulus of these factors, central nervous system's adjusting is hindered, the autonomic nerve system hormonal system functional disorder (as suprarenalism) of unifying, can make slow blood flow, medium and small continuous vessel spasm, the blood vessel wall malnutrition, thrombosis and lumen of vessels obturation, come off at local organization ischemia, necrosis.Work as secondary infection, the pain increased.At present, the Therapeutic Method of primary disease, the traditional Chinese medical science is used YANGHE TANG more, and Radix Angelicae Pubescentis et Herba Taxilli Decoction, XUEFUZHUYU TANG, TAOREN SIWU TANG, SIMIAOYONGAN TANG, Gu Butang, decoction of ten powerful tonics, RENSHEN YANGRONG TANG, attached osmanthus eight flavor balls, ZHIBAI DIHUANG WAN etc. are according to the treatment of state of an illness plus-minus.Doctor trained in Western medicine adopts Pimobendane more, and severe infections all cooperates antibiotic therapy, and the person of failing to respond to any medical treatment, end-stage patients' extremity gangrene cuts the amputation of toe or Different Plane.Operative therapy not only patient has certain misery, the more important thing is deformity, has increased burden for family and society.Pharmacotherapy, Western medicine also do not have effect medicine preferably at present.Concerning the traditional Chinese medical science, because existing Chinese medicine preparation, ignored the complexity of the pertinacious disease cause of disease, drug component and consumption unreasonable causes therapeutic effect relatively poor.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of thromboangiitis obliterans, have the very significant advantage of therapeutic effect.
Solution of the present invention is based on motherland's Chinese medicine and pharmacy theory, in conjunction with understanding to the nature Changing Pattern, through clinical practice for many years, filter out from motherland medicine treasure-house that heat clearing away, yin nourishing, removing heat from blood, dehumidifying, detoxifcation, recuperating depleted YANG are promoted blood circulation, the pure Chinese medicine of blood circulation promoting and blood stasis dispelling, skim the cream off milk, make it have the effect of blood vessel dilating, thrombus, blood circulation promoting, the local blood supply state of change, improve body immunity.
Proportioning raw materials of the present invention (with weight portion):
Formica fusca 0.5～9 big gun Squama Manis 1～9 Radix Glycyrrhizae 1～15
Semen Persicae 0.5～3 Rhizoma Curcumae 2～9 Radix Salviae Miltiorrhizaes 1～5
Radix Clematidis 1～3 Radix Achyranthis Bidentatae 1～3 Radix Angelicae Sinensis 1～30
Rhizoma Corydalis 0.5～3 Fructus Forsythiae 1～15 rhizoma sparganic 0.5～3
Fructus Chaenomelis 1～3 Pheretima 1～3 Flos Carthami 0.5～3
The Radix Rehmanniae 1～15 Cortex Cinnamomi 0.5～3 Rhizoma Zingiberis 1～3
Radix Aconiti Lateralis Preparata 1～3 Radix Paeoniae Alba 1～3 Rhizoma Chuanxiong 1～3
Rhizoma Atractylodis 1～3 Sanguis Draxonis 0.4～1 Radix Ilicis Pubescentis 0.5～3
Hirudo 0.4～1 worm 0.4～1 Caulis Spatholobi 1～4
Semen Coicis 1～7 Bi 1～4 Ramulus Cinnamomi 1～3
Herba Asari 0.3～1 Herba Taraxaci 1～5 Rhizoma Smilacis Glabrae 1～12
Olibanum 1～3 Radix Bupleuri 0.5～3 Rhizoma Anemarrhenae 1～12
Preferred weight (part) ratio range of preparation Chinese medicine preparation of the present invention is:
Formica fusca 0.5～5 big gun Squama Manis 2～5 Radix Glycyrrhizaes 2～10
Semen Persicae 0.8～2 Rhizoma Curcumae 1～3 Radix Salviae Miltiorrhizae 2～3
Radix Clematidis 1.5～2 Radix Achyranthis Bidentataes 1.3～2 Radix Angelicae Sinensis 5～20
Rhizoma Corydalis 0.8～2 Fructus Forsythiae 3～12 rhizoma sparganic 0.8～2
Fructus Chaenomelis 1.3～2 Pheretimas 1.3～2 Flos Carthamis 0.8～2
The Radix Rehmanniae 3～12 Cortex Cinnamomis 0.7～2 Rhizoma Zingiberis 1.5～2
Radix Aconiti Lateralis Preparata 2～2.5 Radix Paeoniae Albas 1.5～2 Rhizoma Chuanxiongs 0.9～2
Rhizoma Atractylodis 1.5～2 Sanguis Draxonis 0.5～0.7 Radix Ilicis Pubescentis 1～2.5
Hirudo 0.46～0.7 worm 0.46～0.7 Caulis Spatholobi 2.3～3
Semen Coicis 2～5 Bi 2～3 Ramulus Cinnamomi 1.5～2
Herba Asari 0.4～0.8 Herba Taraxaci 2～3 Rhizoma Smilacis Glabraes 3～10
Olibanum 1.5～2 Radix Bupleuri 0.8～2 Rhizoma Anemarrhenae 3～10
The optimum weight of Chinese medicine preparation of the present invention (part) ratio range is:
Formica fusca 2 big gun Squama Manis 1.5 Radix Glycyrrhizaes 3
Semen Persicae 0.8 Rhizoma Curcumae 2.3 Radix Salviae Miltiorrhizaes 2.5
Radix Clematidis 1.3 Radix Achyranthis Bidentataes 1.3 Radix Angelicae Sinensis 15
Rhizoma Corydalis 0.8 Fructus Forsythiae 12 rhizoma sparganic 0.8
Fructus Chaenomelis 1.3 Pheretimas 1.3 Flos Carthamis 0.8
The Radix Rehmanniae 12 Cortex Cinnamomis 0.7 Rhizoma Zingiberis 1.5
Radix Aconiti Lateralis Preparata 2.3 Radix Paeoniae Albas 1.5 Rhizoma Chuanxiongs 0.9
Rhizoma Atractylodis 1.5 Sanguis Draxonis 0.5 Radix Ilicis Pubescentis 2.3
Hirudo 0.5 worm 0.5 Caulis Spatholobi 2.3
Semen Coicis 4.6 Bi 2.3 Ramulus Cinnamomi 1.5
Herba Asari 0.5 Herba Taraxaci 2.3 Rhizoma Smilacis Glabraes 9.2
Olibanum 1.5 Radix Bupleuri 0.8 Rhizoma Anemarrhenae 9
The production method of above-mentioned each component being made Chinese medicine preparation of the present invention is:
1, Formica fusca, big gun Squama Manis are worn into coarse powder, all the other medicine fragmentations;
2, the total amount input is carried jar, and the octuple water logging that adds weight was steeped 6 hours, decocted filtration in 40 minutes, adds six times of water gagings again and decocts 30 minutes after-filtration, merges filtrate twice;
3, filtrate concentrates (contracting to 1ml by the 1g crude drug);
4, adding ethanol makes the alcohol amount of containing reach 60-70% to stir evenly, left standstill 24 hours, cross the leaching supernatant, get ethanol and reach relative density more than 1.10;
5, get above-mentioned concentrated solution and add an amount of food starch, dry in the shade, porphyrize, cross 120 mesh sieves and make powder;
6, can incapsulate the in bulk agent by every 0.5g.
The instructions of taking of Chinese medicine preparation of the present invention: three times on the one, each 1 gram is to 3 grams, and open in vain and send down one hour ante cibum.
Chinese medicine preparation of the present invention shows that through clinical use result following advantage is arranged:
1, because described medical material: Formica fusca has antiinflammatory, the analgesic significantly acts on, and helps to eliminate immune complex in the body, can control the inferior limb ulcer; But big gun Squama Manis promoting blood circulation and stopping pain, collateral dredging reduce phlegm; But Radix Glycyrrhizae heat-clearing and toxic substances removing, relieving spasm to stop pain; Semen Persicae can be invigorated blood circulation except that the stasis of blood; But Rhizoma Curcumae removing blood stasis promoting the circulation of QI to relieve pain; Pain, nourishing blood to tranquillize the mind but Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, removing heat from blood disappear; But Radix Clematidis wind-damp dispelling, the meridian dredging, Zhi Paralysis pain; But the Radix Achyranthis Bidentatae blood circulation promoting and blood stasis dispelling, inducing diuresis for treating stranguria syndrome, conducting blood to flow downwards; But Radix Angelicae Sinensis blood circulation promoting and enriching; Rhizoma Corydalis can be invigorated blood circulation, circulation of qi promoting, pain relieving; But Fructus Forsythiae heat-clearing and toxic substances removing, medicinal powder for relieving pain knot; But rhizoma sparganic removing blood stasis eliminating stagnation; But Fructus Chaenomelis relaxing muscles and tendons to promote blood circulation, removing dampness; But Pheretima clearing heat for calming endogenous wind, collateral dredging, diuresis; But Flos Carthami blood circulation promoting and blood stasis dispelling; But Radix Rehmanniae clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting; But the Cortex Cinnamomi warming middle-JIAO is supporing yang, dispersing cold for relieving pain; But the Rhizoma Zingiberis warming middle-JIAO is supporing yang, warming the lung for resolving phlegm, regulating menstruation, hemostasis; That but the Radix Aconiti Lateralis Preparata recuperating depleted YANG is rescued is late, warming the kidney to activate YANG, warming middle-JIAO to relieve pain; But Radix Paeoniae Alba suppressing liver-YANG, easing the affected liver to relieve pain, preserving YIN with astringents and nourishing blood; But the Rhizoma Chuanxiong pain relieving, invigorate blood circulation, circulation of qi promoting; Rhizoma Atractylodis can drying damp and strengthening spleen, expelling wind and removing dampness; But Sanguis Draxonis hemostasis and pain-relieving, blood stasis dispelling expelling pus and promoting granulation; Radix Ilicis Pubescentis can be invigorated blood circulation, blood stasis dispelling, heat-clearing and toxic substances removing, expelling phlegm for arresting cough; But Hirudo removing blood stasis, collateral dredging repercussive; But Eupolyphaga seu steleophaga removing blood stasis, reunion of fractured tendons and bones; But Caulis Spatholobi blood circulation promoting and enriching, relaxing muscles and tendons and activating QI and blood in the collateral; But Semen Coicis promoting diuresis to eliminate damp pathogen, clearing away heat and discharging pus, invigorating the spleen to arrest diarrhea; But turbid, the wind-damp dispelling of Bi dampness removing; But Ramulus Cinnamomi diaphoresis expelling pathogenic factors from muscles, warming the meridian for promoting the flow of YANG QI; Herba Asari can be delivered cold expelling, wind-expelling pain-stopping, warming the lung for resolving phlegm; But Herba Taraxaci heat-clearing and toxic substances removing, dampness removing are good for the stomach; The Rhizoma Smilacis Glabrae sharp joint of can detoxifying, dehumidify; Olibanum can be invigorated blood circulation, pain relieving, granulation promoting; But Radix Bupleuri reducing fever by reconciliation, soothing liver-QI for relieving depression, elevate a turnable ladder yang-energy; But Rhizoma Anemarrhenae clearing away heat and nourishing YIN, the lung moistening and production of body fluid promoting.Comprehensively respectively the distinguish the flavor of effect of Chinese medicine of the present invention makes prescription not only have the effect of the dehumidifying of invigorating blood circulation, and fruit of detoxifcation, removing heat from blood is arranged.Therefore, thromboangiitis obliterans patient takes the present invention's Chinese medicine preparation, and therapeutic effect is very remarkable.
2, because the present invention be a pure Chinese medicinal preparation, each component all meets the relevant pharmaceutical control law of country and stipulates that preparation reaches the national drug sanitary standard, therefore, and to the human body nonhazardous and have no side effect.
3, because the present invention is a Chinese medicine preparation, need not decoct, so patient's taking convenience.
For showing the therapeutic effect of the present invention, below provide relevant clinical observation on the therapeutic effect data to thromboangiitis obliterans.The present invention selects to have 51 examples of system documentation to be the object of observation from 103 clinographies of filing of Taiyuan neurosurgery specialized rehabilitation hospital, male's 37 examples wherein, women's 14 examples, age is at 23-85 between year, the course of disease more than half a year to more than 30 years, the patient mostly is obstinate or heal back recurrence, the heavier person of the state of an illness, and is from various parts of the country.
Diagnostic classification:
According to medical history, symptom, sign, generally sufferer is divided into three kinds:
(1) light disease: side lower limb are afraid of cold, acra is numb, whiteness of skin, amyotrophy, walk shank distending pain, cramp.
(2) serious symptom: the lower limb acrodynia continues, and intermittent claudication is obvious, and dorsal artery of foot is beaten and weakened or disappears, and toes continue to turn cold, palor, livid purple, even occur gangrenous.
(3) did a section toe operation.
Therapeutic Method:
Press preceding method three times on the one, each 1-3 gram, taking 30 continuously is a course of treatment, generally needs to treat 1-4 the course of treatment, can reach effect preferably.
Curative effect judging standard:
1, cures: transference cure.
2, effective: sx.
Therapeutic outcome:
From clinical manifestation, in the 51 routine objects of observation, light disease 1 example is arranged, serious symptom 41 examples, 9 examples of cutting the toe post-operative treatment.The light disease of 1 example is promptly complete after a course of treatment.In 41 routine serious symptoms, all effective after first course of therapy, after second course of treatment, there are 6 examples to cure, after the 3rd course of treatment, there are 29 examples to cure again, after the 4th course of treatment, there are 4 examples to cure again, cure rate reaches 95.1%.Do in the case of cutting the toe operation at 9, sx was in various degree all arranged after first and second course of treatment, after the 3rd course of treatment, have 3 examples to cure, after the 4th course of treatment, have 5 examples to cure, cure rate reaches 88.9%.Integrate, the cure rate of the 51 routine objects of observation reaches 94.1%, effective percentage 100%, statistics tabulation 1.As seen the present invention has very notable therapeutic effect to thromboangiitis obliterans.
Table 1 therapeutic effect statistical table
| The course of treatment | Clinical manifestation (number) | Therapeutic effect (%) | |||
| Light disease | Serious symptom | Did and cut the toe operation | |||
| First course of treatment | Effectively | ??1 | ??41 | ??9 | ??100％ |
| Cure | ??1 | ??1.9％ | |||
| Second course of treatment | Cure | ??6 | ??13.7％ | ||
| The 3rd course of treatment | Cure | ??29 | ??3 | ??76.5％ | |
| The 4th course of treatment | Cure | ??4 | ??5 | ??94.1％ | |
| Therapeutic effect | Effectively | ??100％ | ??100％ | ??100％ | ??100％ |
| Cure | ??100％ | ??95％ | ??88.9％ | ??94.1％ | |
In order to prove that the present invention has the verity of significant curative effect, introduce three model cases below:
(1) Li Haijun, man, 33 years old, Beishan Mountain village, Yuan Cun township, Gaoping City, Shanxi Province, peasant.98 year autumn found that double-legged toe is painful, fiber crops, cool, through the People's Hospital, Gaoping City, institute of traditional Chinese medicine's transfusion, the unsatisfactory curative effect of taking medicine, 99 year winter toe festers, severe pain, go to Changzhi peace hospital to do a section toe operation, the state of an illness is not felt any better, two lower limb muscles atrophys, wound is suppurated, and the high amputation operative treatment is done in school's suggestion again.On July 3rd, 2000 was taken Chinese medicine of the present invention, and curative effect is obvious after first course of treatment, suppurate end, alleviation of pain is light, obey again after second course of treatment that JIUYUE letter on the 6th claims not bitterly, the incrustation of festering, can walk.And mail photo (Fig. 1, Fig. 2).
(2) He Changhong, man, 42 years old, Yicheng County, Shanxi Province west Yan Zhen fort Bei Hewancun, peasant.Sensation right lower extremity numbness in 1993, feel cold, the shank acid of walking is expanded, after 1 year, blue, the swelling of right crus of diaphragm, multi-treatment is invalid, in JIUYUE, 1998 little toe fester, severe pain.On April 26th, 1999 was taken Chinese medicine of the present invention, after first course of treatment, and pain relief, disease takes a turn for the better, and takes the basic healing of festering after second and third course of treatment, disease disappears, and mails photo (Fig. 3,4) on July 2nd, 1999.
(3) Yang Ruiqi, man 51 years old, Sun Jia village village, Sun Jiazhuan township, Yu County, Shanxi Province, peasant.Blackening extends to foot after the nineteen ninety right lower limb redness, and invalid through multi-treatment, the back is by People's Hospital of Shanxi Prov.'s operation, and still right little toe festers, and redness alleviates after clothes on July 20th, 2000 treatment by Chinese herbs of the present invention course of treatment, and foot is not numb, and little finger of toe begins incrustation.After obey the Chinese medicine of the present invention of two courses of treatment again, complete, can ownly walk, slough all comes off, through the check of fighting as volume, right crus of diaphragm 1,2,3 toe ripples are lower slightly than the right crus of diaphragm toe, amplitude 4.5mm, left foot toe amplitude is 5mm.The back does not have recurrence.Photo on January 4th, 2002 (Fig. 5,6).
Description of drawings
Fig. 1 is before patient Lee's navy uniform is used Chinese medicine of the present invention, foot, leg disease feelings photo;
Fig. 2 for patient Li Haijun through taking the photo of Chinese medicine of the present invention after two courses of treatment;
Fig. 3 is for before patient He Changhong takes Chinese medicine of the present invention, the right crus of diaphragm little toe state of an illness photo that festers;
Fig. 4 for patient He Changhong through taking the photo of Chinese medicine of the present invention after three courses of treatment;
Fig. 5 takes the preceding right crus of diaphragm little toe state of an illness photo of Chinese medicine of the present invention for patient Yang Ruiqi;
Fig. 6 for patient Yang Ruiqi through taking the photo of Chinese medicine of the present invention after three courses of treatment.
The specific embodiment
Embodiment 1:
Take by weighing raw material (kilogram) by following proportioning:
Formica fusca 0.5 big gun Squama Manis 1 Radix Glycyrrhizae 1
Semen Persicae 0.5 Rhizoma Curcumae 2 Radix Salviae Miltiorrhizaes 1
Radix Clematidis 1 Radix Achyranthis Bidentatae 1 Radix Angelicae Sinensis 15
Rhizoma Corydalis 0.5 Fructus Forsythiae 12 rhizoma sparganic 0.5
Fructus Chaenomelis 1 Pheretima 1 Flos Carthami 0.5
The Radix Rehmanniae 12 Cortex Cinnamomis 0.5 Rhizoma Zingiberis 1
Radix Aconiti Lateralis Preparata 1 Radix Paeoniae Alba 1 Rhizoma Chuanxiong 1
Rhizoma Atractylodis 1 Sanguis Draxonis 0.4 Radix Ilicis Pubescentis 0.5
Hirudo 0.4 worm 0.4 Caulis Spatholobi 1
Semen Coicis 4 Bi 2 Ramulus Cinnamomi 1
Herba Asari 0.3 Herba Taraxaci 2 Rhizoma Smilacis Glabraes 8
Olibanum 1 Radix Bupleuri 0.5 Rhizoma Anemarrhenae 8
Production method is as follows:
(1) Formica fusca, big gun Squama Manis are worn into coarse powder, all the other medicine fragmentations;
(2) the total amount input is carried jar, and the octuple water logging that adds weight was steeped 6 hours, decocted filtration in 40 minutes, adds six times of water gagings again and decocts 30 minutes after-filtration, merges filtrate twice;
(3) contract to 1ml by the 1g crude drug and concentrate;
(4) adding ethanol makes amount of alcohol reach 60-70% to stir, left standstill 24 hours, filter, get supernatant, get ethanol and reach relative density more than 1.10;
(5) get that above-mentioned concentrated solution adds proper amount of edible starch, dries in the shade, porphyrize, cross 120 mesh sieves and make powder;
(6) can incapsulate by every 0.5g.
Embodiment 2:
Take by weighing raw material (kilogram) by following proportioning:
Formica fusca 5 big gun Squama Manis 5 Radix Glycyrrhizaes 10
Semen Persicae 2 Rhizoma Curcumae 3 Radix Salviae Miltiorrhizaes 3
Radix Clematidis 2 Radix Achyranthis Bidentataes 2 Radix Angelicae Sinensis 20
Rhizoma Corydalis 2 Fructus Forsythiaes 12 rhizoma sparganic 2
Fructus Chaenomelis 2 Pheretimas 2 Flos Carthamis 2
The Radix Rehmanniae 12 Cortex Cinnamomis 2 Rhizoma Zingiberiss 2
Radix Aconiti Lateralis Preparata 2.5 Radix Paeoniae Albas 2 Rhizoma Chuanxiongs 2
Rhizoma Atractylodis 2 Sanguis Draxonis 0.7 Radix Ilicis Pubescentis 2.5
Hirudo 0.7 worm 0.7 Caulis Spatholobi 3
Semen Coicis 5 Bi 3 Ramulus Cinnamomi 2
Herba Asari 0.8 Herba Taraxaci 3 Rhizoma Smilacis Glabraes 10
Olibanum 2 Radix Bupleuri 2 Rhizoma Anemarrhenaes 10
Production method is with embodiment 1.
Claims (5)
1, a kind of Chinese medicine preparation for the treatment of thromboangiitis obliterans, it is characterized in that: the weight proportion of each raw material is:
Formica fusca 0.5～9 big gun Squama Manis 1～9 Radix Glycyrrhizae 1～15
Semen Persicae 0.5～3 Rhizoma Curcumae 2～9 Radix Salviae Miltiorrhizaes 1～5
Radix Clematidis 1～3 Radix Achyranthis Bidentatae 1～3 Radix Angelicae Sinensis 1～30
Rhizoma Corydalis 0.5～3 Fructus Forsythiae 1～15 rhizoma sparganic 0.5～3
Fructus Chaenomelis 1～3 Pheretima 1～3 Flos Carthami 0.5～3
The Radix Rehmanniae 1～15 Cortex Cinnamomi 0.5～3 Rhizoma Zingiberis 1～3
Radix Aconiti Lateralis Preparata 1～3 Radix Paeoniae Alba 1～3 Rhizoma Chuanxiong 1～3
Rhizoma Atractylodis 1～3 Sanguis Draxonis 0.4～1 Radix Ilicis Pubescentis 0.5～3
Hirudo 0.4～1 worm 0.4～1 Caulis Spatholobi 1～4
Semen Coicis 1～7 Bi 1～4 Ramulus Cinnamomi 1～3
Herba Asari 0.3～1 Herba Taraxaci 1～5 Rhizoma Smilacis Glabrae 1～12
Olibanum 1～3 Radix Bupleuri 0.5～3 Rhizoma Anemarrhenae 1～12
Formica fusca, big gun Squama Manis are worn into coarse powder, all the other fragmentations; The total amount input is carried jar, and the octuple water logging that adds weight was steeped 6 hours, decocted filtration in 40 minutes, adds six times of water gagings again and decocts 30 minutes after-filtration, merges filtrate twice; It is concentrated to 1ml to contract by the 1g crude drug; Adding ethanol makes the alcohol amount of containing reach 60-70% to stir evenly, left standstill 24 hours, cross the leaching supernatant, get ethanol and reach relative density more than 1.10; Get above-mentioned concentrated solution and add an amount of food starch, dry in the shade, porphyrize, cross 120 mesh sieves and make powder.
2, according to the described a kind of Chinese medicine preparation for the treatment of thromboangiitis obliterans of claim 1, the weight proportion of its each raw material is:
Formica fusca 0.5～5 big gun Squama Manis 2～5 Radix Glycyrrhizaes 2～10
Semen Persicae 0.8～2 Rhizoma Curcumae 1～3 Radix Salviae Miltiorrhizae 2～3
Radix Clematidis 1.5～2 Radix Achyranthis Bidentataes 1.3～2 Radix Angelicae Sinensis 5～20
Rhizoma Corydalis 0.8～2 Fructus Forsythiae 3～12 rhizoma sparganic 0.8～2
Fructus Chaenomelis 1.3～2 Pheretimas 1.3～2 Flos Carthamis 0.8～2
The Radix Rehmanniae 3～12 Cortex Cinnamomis 0.7～2 Rhizoma Zingiberis 1.5～2
Radix Aconiti Lateralis Preparata 2～2.5 Radix Paeoniae Albas 1.5～2 Rhizoma Chuanxiongs 0.9～2
Rhizoma Atractylodis 1.5～2 Sanguis Draxonis 0.5～0.7 Radix Ilicis Pubescentis 1～2.5
Hirudo 0.46～0.7 worm 0.46～0.7 Caulis Spatholobi 2.3～3
Semen Coicis 2～5 Bi 2～3 Ramulus Cinnamomi 1.5～2
Herba Asari 0.4～0.8 Herba Taraxaci 2～3 Rhizoma Smilacis Glabraes 3～10
Olibanum 1.5～2 Radix Bupleuri 0.8～2 Rhizoma Anemarrhenae 3～10
3, according to the described a kind of Chinese medicine preparation for the treatment of thromboangiitis obliterans of claim 2, the weight proportion of its each raw material is:
Formica fusca 2 big gun Squama Manis 1.5 Radix Glycyrrhizaes 3
Semen Persicae 0.8 Rhizoma Curcumae 2.3 Radix Salviae Miltiorrhizaes 2.5
Radix Clematidis 1.3 Radix Achyranthis Bidentataes 1.3 Radix Angelicae Sinensis 15
Rhizoma Corydalis 0.8 Fructus Forsythiae 12 rhizoma sparganic 0.8
Fructus Chaenomelis 1.3 Pheretimas 1.3 Flos Carthamis 0.8
The Radix Rehmanniae 12 Cortex Cinnamomis 0.7 Rhizoma Zingiberis 1.5
Radix Aconiti Lateralis Preparata 2.3 Radix Paeoniae Albas 1.5 Rhizoma Chuanxiongs 0.9
Rhizoma Atractylodis 1.5 Sanguis Draxonis 0.5 Radix Ilicis Pubescentis 2.3
Hirudo 0.5 worm 0.5 Caulis Spatholobi 2.3
Semen Coicis 4.6 Bi 2.3 Ramulus Cinnamomi 1.5
Herba Asari 0.5 Herba Taraxaci 2.3 Rhizoma Smilacis Glabraes 9.2
Olibanum 1.5 Radix Bupleuri 0.8 Rhizoma Anemarrhenae 9
4, according to claim 1,2 or 3 described a kind of manufacture methods for the treatment of the Chinese medicine preparation of thromboangiitis obliterans, it is characterized in that processing step is:
(1) Formica fusca, big gun Squama Manis are worn into coarse powder, all the other medicine fragmentations;
(2) the total amount input is carried jar, and the octuple water logging that adds weight was steeped 6 hours, decocted filtration in 40 minutes, adds six times of water gagings again and decocts 30 minutes after-filtration, merges filtrate twice;
(3) filtrate concentrates (contracting to 1ml by the 1g crude drug);
(4) adding ethanol makes the alcohol amount of containing reach 60-70% to stir evenly, left standstill 24 hours, cross the leaching supernatant, get ethanol and reach relative density more than 1.10;
(5) get above-mentioned concentrated solution and add an amount of food starch, dry in the shade, porphyrize, cross 120 mesh sieves and make powder;
5, according to the described a kind of manufacture method for the treatment of the Chinese medicine preparation of thromboangiitis obliterans of claim 4, it is characterized in that: the powder that makes is incapsulated by every 0.5 gram make the piece agent.
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| Application Number | Priority Date | Filing Date | Title |
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| CNB02135295XA CN1181868C (en) | 2002-08-01 | 2002-08-01 | Chinese medicine prepn for treating obliterans thromboangitis |
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| CNB02135295XA CN1181868C (en) | 2002-08-01 | 2002-08-01 | Chinese medicine prepn for treating obliterans thromboangitis |
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| CN1398625A true CN1398625A (en) | 2003-02-26 |
| CN1181868C CN1181868C (en) | 2004-12-29 |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101711828B (en) * | 2009-12-18 | 2011-06-01 | 李燕宁 | Decoction for promoting blood circulation |
| CN102210799A (en) * | 2011-06-09 | 2011-10-12 | 毕哲全 | Medicament for treating peripheral vascular disease |
| CN101199658B (en) * | 2007-12-19 | 2012-07-18 | 李华君 | Chinese medicine compound for oral administration for treating vasculitis |
| CN103285360A (en) * | 2013-06-09 | 2013-09-11 | 王京涛 | Traditional Chinese medicinal preparation for treating thromboangiitis obliterans, and preparation method thereof |
| CN103585410A (en) * | 2013-10-18 | 2014-02-19 | 尹静 | Traditional Chinese medicine composition for treating angitis |
| CN104784579A (en) * | 2015-05-14 | 2015-07-22 | 南京华宽信息咨询中心 | Traditional Chinese medicine composition for treating thromboangiitis obliterans |
| CN105288392A (en) * | 2015-11-30 | 2016-02-03 | 吕翠云 | Traditional Chinese medicine for treating thromboangiitis obliterans |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101574510B (en) * | 2009-06-17 | 2011-11-23 | 王凯 | Compound szechuan lovage rhizome and safflower soup used for treating thromboangitis obliterans |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101199658B (en) * | 2007-12-19 | 2012-07-18 | 李华君 | Chinese medicine compound for oral administration for treating vasculitis |
| CN101711828B (en) * | 2009-12-18 | 2011-06-01 | 李燕宁 | Decoction for promoting blood circulation |
| CN102210799A (en) * | 2011-06-09 | 2011-10-12 | 毕哲全 | Medicament for treating peripheral vascular disease |
| CN102210799B (en) * | 2011-06-09 | 2012-08-08 | 毕哲全 | Medicament for treating peripheral vascular disease |
| CN103285360A (en) * | 2013-06-09 | 2013-09-11 | 王京涛 | Traditional Chinese medicinal preparation for treating thromboangiitis obliterans, and preparation method thereof |
| CN103285360B (en) * | 2013-06-09 | 2014-09-17 | 王京涛 | Traditional Chinese medicinal preparation for treating thromboangiitis obliterans, and preparation method thereof |
| CN103585410A (en) * | 2013-10-18 | 2014-02-19 | 尹静 | Traditional Chinese medicine composition for treating angitis |
| CN103585410B (en) * | 2013-10-18 | 2015-07-08 | 尹静 | Traditional Chinese medicine composition for treating angitis |
| CN104784579A (en) * | 2015-05-14 | 2015-07-22 | 南京华宽信息咨询中心 | Traditional Chinese medicine composition for treating thromboangiitis obliterans |
| CN105288392A (en) * | 2015-11-30 | 2016-02-03 | 吕翠云 | Traditional Chinese medicine for treating thromboangiitis obliterans |
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