CN1395941A - Oral liquid of strawflower - Google Patents

Oral liquid of strawflower Download PDF

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Publication number
CN1395941A
CN1395941A CN 01122725 CN01122725A CN1395941A CN 1395941 A CN1395941 A CN 1395941A CN 01122725 CN01122725 CN 01122725 CN 01122725 A CN01122725 A CN 01122725A CN 1395941 A CN1395941 A CN 1395941A
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CN
China
Prior art keywords
moench
linn
helichrysum
filter
oral liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN 01122725
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Chinese (zh)
Inventor
殷德孝
陈友林
关丽俊
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
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Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN 01122725 priority Critical patent/CN1395941A/en
Publication of CN1395941A publication Critical patent/CN1395941A/en
Pending legal-status Critical Current

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Abstract

An oral liquid for treating acute or chronic nephritis is prepared from growing-in-sand strawflower through extracting flavone and flavonoside in water, and depositing in alcohol. Its advantages are high curative effect, low toxic by-effect, and no recurrence.

Description

Oral liquid of strawflower
Technical field
The present invention relates to a kind of simple prescription preparation, be used in particular for treating acute and chronic nephritis.
Technical background
The acute and chronic nephritis of treatment treatment is at present generally lain up diet control and symptomatic treatment clinically.According to " nephrology " (Wang Haiyan edits second edition) record, to acute nephritis lie up, diet control, symptomatic treatment, key link is prevention and treatment water, sodium retention, the control circulating blood volume, thereby reach the purpose of mitigation symptoms.The acute and chronic nephritis course of disease is long, cures difficulty.According to another the query report that Chinese Chinese medicine documentation retrieval centre Shanghai Univ. of Traditional Chinese Medicine branch center provides, do not see research report with Helichrysum arenarium (Linn.) Moench. treatment acute and chronic nephritis.
Summary of the invention
The present invention is for to make through water extract-alcohol precipitation with the herb of Compositae helichrysum Helichrysum arenarium (Linn.) Moench. Helichrysum arenarium (L.) Moench.The active substance of its treatment nephritis is the total extract of Helichrysum arenarium (Linn.) Moench..Aqueous solution is brown supernatant liquid, and it is sweet to distinguish the flavor of, and little hardship, main component are flavone and flavonoid glycoside, and extracting solution also can be made into granule, tablet, capsule or injection after further concentrating.Finished product is differentiated in order to following method: 1. get this product 1ml, add a little magnesium powder jolting, add 3 of concentrated hydrochloric acid, in 1-2 minute (heating in case of necessity), solution is existing red.2. get control medicinal material 0.5g, add water 5ml, reflux 10 minutes is put cold filtration, and filtrate is concentrated into about 0.5ml, compares liquid.Other gets this product is need testing solution, the photograph thin layer chromatography (" appendix VIB of Chinese pharmacopoeia version in 2000) test.Draw above-mentioned two kinds of solution, put respectively on same silica gel g thin-layer plate, get upper strata liquid with ethyl acetate-formic acid-water (10: 2: 3) and do developing solvent, launch the back and take out airing, spray 2% aluminum chloride alcoholic solution, put under the uviol lamp (365nm) and inspect.In the test sample chromatograph, be on the corresponding position of reference substance chromatograph, show the fluorescence speckle of same color respectively.This invention is used for the treatment of acute and chronic nephritis, and effect is obvious, can take effect after general 10 days, and very fast healing, promptly every test rating returns to normal value gradually, significantly shortens the course of disease without this medicine treatment.With this medicine surplus healing in general January, to treat the several months continuously without this medicine treatment acute and chronic nephritis, the patient several years that has all can not heal entirely.
The specific embodiment
Be unit below, the oral liquid of strawflower manufacture method is specified with Helichrysum arenarium (Linn.) Moench. 500g.
Get Helichrysum arenarium (Linn.) Moench. 500g, add water boil three times, each one hour, filter, merging filtrate, normal pressure (or decompression) is concentrated into about 500ml, puts coldly, adds ethanol 500ml, stir evenly, left standstill 24 hours, filter, decompression filtrate recycling ethanol also is concentrated into about 450ml, with sucrose 50g, and dissolving, add water and make cumulative volume 500ml, stir evenly, filter, fill, sterilization, promptly.
This oral liquid trial employment period is not seen obvious toxic-side effects.Taking convenience, curative effect is obvious.Instructions of taking: the state of an illness promptly take a favorable turn in every day three times, the each 10-20ml, general patient 10 days, take January continuously after, every test rating can return to normal value gradually, cures the back and is difficult for recurrence.
Character this product is brown supernatant liquid, and it is sweet to distinguish the flavor of, little hardship.
Function is used for the treatment of acute and chronic nephritis with curing mainly.
Consumption and usage every day three times, each 10ml-20ml.
The every bottled 10ml of specification, every milliliter of oral liquid is equivalent to medical material 1 gram.
Storage seals, puts shady and cool place.
Helichrysum arenarium (Linn.) Moench. is the feverfew that is grown in the north, Xinjiang and Central Asia.This plant is a herbaceos perennial, and regeneration capacity is strong, and resource can satisfy large-scale industrial production and use, production technology all is conventional production technology, and no special installation, working condition adopt the national medical GMP of manufacturing enterprise standard, therefore, this oral liquid can carry out industrial-scale production.

Claims (1)

1 oral liquid of strawflower is to make through water extract-alcohol precipitation with the herb of Compositae helichrysum Helichrysum arenarium (Linn.) Moench. Helichrysumarenarium (L.) Moench.The active substance of its treatment nephritis is the total extract of Helichrysum arenarium (Linn.) Moench., and main component is flavone and flavonoid glycoside, it is characterized in that: get Helichrysum arenarium (Linn.) Moench. 500g and add water boil three times, each one hour, filter, merging filtrate, normal pressure (or decompression) is concentrated into about 500ml, puts cold, add ethanol 500ml, stir evenly, left standstill 24 hours, filter, decompression filtrate recycling ethanol also is concentrated into about 450ml, with sucrose 50g, dissolving adds water and makes cumulative volume 500ml, stirs evenly, filter fill, sterilization.
CN 01122725 2001-07-12 2001-07-12 Oral liquid of strawflower Pending CN1395941A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 01122725 CN1395941A (en) 2001-07-12 2001-07-12 Oral liquid of strawflower

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 01122725 CN1395941A (en) 2001-07-12 2001-07-12 Oral liquid of strawflower

Publications (1)

Publication Number Publication Date
CN1395941A true CN1395941A (en) 2003-02-12

Family

ID=4664861

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 01122725 Pending CN1395941A (en) 2001-07-12 2001-07-12 Oral liquid of strawflower

Country Status (1)

Country Link
CN (1) CN1395941A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007083190A3 (en) * 2006-01-17 2007-10-18 Aboca S P A Water insoluble helichrysum extract, process for preparing the same and uses thereof
WO2016120241A1 (en) * 2015-01-28 2016-08-04 Purytra Farmaceutici S.P.A. Process for the preparation of a helichrysum-based product

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007083190A3 (en) * 2006-01-17 2007-10-18 Aboca S P A Water insoluble helichrysum extract, process for preparing the same and uses thereof
US8147878B2 (en) 2006-01-17 2012-04-03 Aboca S.P.A. Societa' Agricola Water insoluble helychrisum extract, process for preparing the same and uses thereof
WO2016120241A1 (en) * 2015-01-28 2016-08-04 Purytra Farmaceutici S.P.A. Process for the preparation of a helichrysum-based product

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C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication