CN1392264A - Process for preparing easy body absorption protein ion and health food produced therefrom - Google Patents
Process for preparing easy body absorption protein ion and health food produced therefrom Download PDFInfo
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- CN1392264A CN1392264A CN 01121933 CN01121933A CN1392264A CN 1392264 A CN1392264 A CN 1392264A CN 01121933 CN01121933 CN 01121933 CN 01121933 A CN01121933 A CN 01121933A CN 1392264 A CN1392264 A CN 1392264A
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- iron
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- oligopeptide
- ion
- protein ion
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Abstract
The present invention relates to the preparation process of protein iron. The process includes setting protein in pure water and acid regulation to obtain suspension of pH 4.5-5.0; adding protein decomposing enzyme and reacting for 8-10 hr to obtain oligopeptide; adding iron ion and chelating and alkali neutralizing to pH 6.8-7.2 to obtain inorganic iron chelate compound; concentrating to a solid component content of 35%, adding alcohol to deposit; and drying the iron-oligopeptide precipitate to obtain powder. The protein iron easy to be absorbed by body may be used in preparing beverage, capsuled or tablet to eliminate the problem of iron deficiency.
Description
The present invention relates to easily by the preparation method of the systemic protein ion of body and the beverage or the food compositions that contain it.Its particular content is, and is outstanding turbid in water vegetalitas or animal protein, reacts for a long time under the slightly acidic state after adding bromeline, obtains oligopeptide.In the oligopeptide of protein,split, add iron ion then, carry out chelatropic reaction, obtain oligopeptide iron.Its precipitation, separation, dry up powdered and can obtain Powdered oligopeptide iron again.
It is found that in the past employed mineral-supplemented material mostly can not be absorbed in the body, and can be, just may be absorbed when having only in the analog mobile calcium cpd calmodulin by the mineral compound of little intestinal absorption in the digestive tube.The structure of finding calmodulin depends on the oligopeptide that is chelated with calcium ion, so invented the preparation method of inorganic iron oligopeptide.
Iron is the mineral substance that constitutes blood, plays an important role in the oxygen course of conveying relevant with production capacity.Iron deficiency can cause anaemia, and especially the incidental anaemia phenomenon of women is because imbalance causes between the consumption (pregnancy, lactication, menstruation etc.) of iron and the absorbed dose.Iron is not easy to be absorbed, and means that with people so far the method known to general is difficult to absorb, and therefore had better not think that eating a large amount of iron content foods just can all be absorbed in the body.
Do not say the iron that contains in the plant, eat the blood of animal exactly, also may not necessarily absorb iron, this is because these mostly are the nonabsorbable compositions, can not be utilized by organism.Have only the divalent iron ion of water-soluble protein chelating just can be absorbed, therefore must make great efforts to absorb the day normal content (RDA:Recommended Dietary Allowance) of iron.
Iron in the food can be divided into heme iron (Heme-Fe) and nonheme iron.With the iron cpd that is absorbed as purpose of iron is not the structure of protoheme but protein-iron, and protein-iron is made oxyphorase in marrow.Because haemoglobin molecule is too big, can not pass through cytolemma, so can not be absorbed.If oxyphorase can pass through cytolemma, blood will flow out tissue or external by blood vessel.
As the oxyphorase of heme iron, molecular weight is 64,500, so can not be by integral protein matter (Integral protein) film before the absorption with 24,000～28,000 molecular weight.And nonheme iron generates the soluble iron ion in digestive tube, and it is condensed with the protein bound that constitutes intestinal mucus and mucous membrane, so can not be absorbed.Iron ion is by the tannic acid in the food (Tannin), phosphoric acid, phytinic acid, cellulosic processing the time, the reaction that mutually combines, and become water-insoluble salt state, so can not be absorbed.But nonheme iron is not all can not be absorbed in vivo.If run into the protein digestion thing oligopeptide that generates in digestive process, it becomes the protein-iron form, promptly can be absorbed.So be considered to along with the difference of physique can be variant, reason just here.
Iron is the most responsive to acidifying in inorganics, will be reacidified to water-fast 3 valency iron by the compound of oligopeptide chelating, thereby can not be absorbed.And VITAMIN-A, B
1, B
2, materials such as C and VITAMIN PP can prevent acidifying, improve the functionally active of iron, therefore become ideal iron nutritional supplementation material.
Iron-oligopeptide is diverse iron cpd with in the past used iron cpd on function, can improve the healthy obstacle that brings owing to iron deficioncy.That is to say, electrolyte (Electrolysis) additive and animal blood siccative etc. contain the material of iron, when processing or take care of or in suction process, by acidifying, become water-fast 3 valency iron acidulants, so can not be absorbed owing to the strong acid voltinism of iron.But iron-oligopeptide of the present invention does not just have this shortcoming, to being in menstruation, pregnancy, the women of lactication phase, is that very ideal is mended ferrous products.
And the understanding to iron has had variation in the physiology field recently.The opinion that excessive absorption iron can bring out adult diseases has appearred.Yet this refers to inorganic (Inorganic) iron cpd that causes dissociate (Dissociation) in vivo.Iron-oligopeptide is not mineral compound or organic (Organic) compound that does not absorb, but with the inner complex that protein is formed, not only be absorbed easily, do not have obstacle yet.
The objective of the invention is to prepare with water soluble protein oligopeptide chelating inorganic iron form exist easily by the systemic albumenization of body-iron.
Content of the present invention constitutes: add protease in animality or vegetable protein after, its decomposition is obtained oligopeptide, and then add iron ion and carry out chelatropic reaction, can obtain protein ion.In protein ion, add vitamins and other nutritious components again, preparation beverage or food product consisting thing.
Its concrete grammar is: (1) is outstanding turbid being dissolved in the water of adjusting to pH4.5～5.0 of albumen; (2) adding is equivalent to 1～5% protease in the suspension liquid of (1), reacts 8～10 hours down at 30～40 ℃, obtains oligopeptide; (3) add iron ion in the oligopeptide that (2) obtain, ratio is 1000 parts of oligopeptides: the iron ion of 1 nucleidic mass (55.85 parts), carry out chelatropic reaction after, reaction solution is neutralized; (4) after the iron chelate of the liquid state that (3) are obtained is concentrated to and contains solid formation and divide 35%, add alcohol precipitation and separate, dry up the iron oligopeptide of making pulverulence then.
Above selected protein be in vegetalitas or the animality any, and protease is a bromeline.
In addition, the protective foods of protein ion beverage of the present invention is: will be dissolved into the protein ion solution of weight 87.97～87.85% by iron-oligopeptide that aforesaid method obtains in pure water, add weight percent again and be respectively VITAMIN-C 0.01～0.05%, VITAMIN-B
10.01 VITAMIN-B～0.05%,
20.01～0.05%, fructose 12.0% is made into beverage.The present invention also comprises the capsule for preparing behind the moisture of removing in above-mentioned iron oligopeptide and the composition thereof or the protein ion capsule or the protein ion tablet protective foods of tablet specification.
With embodiment the present invention is described below.But content of the present invention is not limited to these embodiment.
＜embodiment 1 〉
As proteinic kind, vegetal soybean protein and gluten, the casein of animality and gelatin can use.100% protein that its moderate purity is accounted for more than 95% is outstanding turbid in 800% water, behind the protease bromeline of interpolation 3%, is adjusted into pH4.5～5.0 with hydrochloric acid, reacts down at 40 ℃ to obtain oligopeptide in 9 hours.Here, filter the water-insoluble amino acid of from the proteolysis thing, separating and remove.Then, by proteolysis thing oligopeptide 1,000 part: the ratio of 1 nucleidic mass of iron ion (55.85 ones) is added iron protochloride, carry out chelatropic reaction, again reaction solution with ammonia pH6.8～7.2 that neutralize, then the solid formation branch of iron chelate is concentrated to 35% concentration, do precipitation with alcohol again, dry then iron-oligopeptide is made powder, obtains iron-oligopeptide.
＜embodiment 2 〉: the preparation of protein ion beverage
Iron-oligopeptide among the embodiment 1 is adjusted to 28% concentration, presses table 1 prescription and cooperate, then according to the normal content (RDA:Recommended Dietary Allowance) of iron, with 12～15mg/ days be benchmark, prepared iron-oligopeptide beverage.
The composition of table 1. beverage (adding up to 100%)
| Composition | Content (weight %) |
| Protein ion solution (28%) | ????87.97 |
| VITAMIN-C | ????0.01 |
| VITAMIN-B 1 | ????0.01 |
| VITAMIN-B 2 | ????0.01 |
| Fructose | ????12.00 |
| Meter | ????100.00 |
＜embodiment 3 〉: with the protein ion is the capsule of effective constituent
The protein ion that is obtained with embodiment 1 is an effective constituent, prepares by table 2, and 0.5g is put in the capsule, has prepared the protein ion capsule.
The capsular composition of table 2. (adding up to 100%)
| Composition | Addition (%) |
| The powder protein ion | ????99.95 |
| VITAMIN-B 1 | ????0.01 |
| VITAMIN-C | ????0.03 |
| VITAMIN-B 2 | ????0.01 |
| Meter | ????100.00 |
＜embodiment 4 〉: with the protein ion is the tablet of effective constituent
Protein ion with acquisition among the embodiment 1 is an effective constituent, prepares by table 3, and tablet causes the 0.5g specification, has prepared the protein ion tablet by the method for generally acknowledging then.
The composition of table 3. tablet (adding up to 100%)
| Composition | Addition (%) |
| The powder protein ion | ????94.95 |
| VITAMIN-B 1 | ????0.01 |
| α-decomposition starch producing | ????4.7 |
| VITAMIN-C | ????0.03 |
| VITAMIN-B 2 | ????0.01 |
| Magnesium Stearate | ????0.3 |
| Meter | ????100.00 |
Integral protein matter (Integral protein) molecular weight before the molecular weight ratio small intestine film of absorptivity protein ion of the present invention absorbs is also little.Therefore not only be absorbed easily, also because of water soluble protein oligopeptide chelating inorganic iron, and do not remained in the interference of food ingredient in the digestive tube, so the absorption of iron is easy in vivo.
Claims (4)
1. easily by the preparation method of the systemic albumenization of body-iron, it is characterized in that comprising the steps:
Protein 100% is outstanding turbid in 800% water, is adjusted into the solution of pH4.5～5.0;
In above-mentioned suspension liquid, add 1～5% protease, reacted 8～10 hours down, the preparation oligopeptide at 30～40 ℃;
Add iron ion and carry out chelatropic reaction in above-mentioned oligopeptide, ratio is 1000 parts of oligopeptides: the iron ion of the divalent of 1 nucleidic mass (55.85 parts), and this is a neutralization reaction;
Above-mentioned aqueous iron chelate is concentrated to contains solid formation and divide 35% concentration, with alcohol precipitation, separate after, drying is made pulverous iron-oligopeptide.
Claim 1 easily by the preparation method of the systemic protein ion of body, it is characterized in that selected protein is any in vegetalitas or the animality, and protease is a bromeline.
3. resulting iron-oligopeptide in the claim 1 is dissolved in the pure water, makes the protein ion of 87.97～87.85 weight %, again with VITAMIN-C of 0.01～0.05 weight %, VITAMIN-B of 0.01～0.05 weight %
1, 0.01～0.05 weight % vitamins B
2With 12% fructose mix make easily by the systemic protein ion drink health-care of body food.
4. after requiring iron-oligopeptide described in 3 and the moisture in the composition thereof to remove aforesaid right, with the protein ion capsule or the protein ion tablet protective foods of capsule or tablet form preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011219335A CN1191371C (en) | 2001-06-20 | 2001-06-20 | Process for preparing easy body absorption protein ion and health food produced therefrom |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011219335A CN1191371C (en) | 2001-06-20 | 2001-06-20 | Process for preparing easy body absorption protein ion and health food produced therefrom |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1392264A true CN1392264A (en) | 2003-01-22 |
| CN1191371C CN1191371C (en) | 2005-03-02 |
Family
ID=4664604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB011219335A Expired - Fee Related CN1191371C (en) | 2001-06-20 | 2001-06-20 | Process for preparing easy body absorption protein ion and health food produced therefrom |
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| Country | Link |
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| CN (1) | CN1191371C (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100344326C (en) * | 2005-09-30 | 2007-10-24 | 北京康比特威创体育新技术发展有限公司 | Iron-supplementing preparation |
| CN101982095A (en) * | 2010-09-09 | 2011-03-02 | 得利斯集团有限公司 | Peptide iron capsule and preparation method thereof |
| CN101480255B (en) * | 2009-01-22 | 2012-10-31 | 得利斯集团有限公司 | Method for producing novel pig blood tofu using pig blood serum and peptide iron |
| CN110934302A (en) * | 2019-11-13 | 2020-03-31 | 安徽全康药业有限公司 | Vitamin mineral tablet for pregnant women |
| CN112574275A (en) * | 2020-11-09 | 2021-03-30 | 广东中食营科生物科技有限公司 | Preparation method of corn oligopeptide chelated iron |
-
2001
- 2001-06-20 CN CNB011219335A patent/CN1191371C/en not_active Expired - Fee Related
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100344326C (en) * | 2005-09-30 | 2007-10-24 | 北京康比特威创体育新技术发展有限公司 | Iron-supplementing preparation |
| CN101480255B (en) * | 2009-01-22 | 2012-10-31 | 得利斯集团有限公司 | Method for producing novel pig blood tofu using pig blood serum and peptide iron |
| CN101982095A (en) * | 2010-09-09 | 2011-03-02 | 得利斯集团有限公司 | Peptide iron capsule and preparation method thereof |
| CN101982095B (en) * | 2010-09-09 | 2013-01-09 | 得利斯集团有限公司 | Peptide iron capsule and preparation method thereof |
| CN110934302A (en) * | 2019-11-13 | 2020-03-31 | 安徽全康药业有限公司 | Vitamin mineral tablet for pregnant women |
| CN112574275A (en) * | 2020-11-09 | 2021-03-30 | 广东中食营科生物科技有限公司 | Preparation method of corn oligopeptide chelated iron |
| CN112574275B (en) * | 2020-11-09 | 2021-08-17 | 广东中食营科生物科技有限公司 | Preparation method of corn oligopeptide chelated iron |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1191371C (en) | 2005-03-02 |
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Granted publication date: 20050302 Termination date: 20120620 |