CN1387872A - Nephropathy treating medicine and its prepn - Google Patents
Nephropathy treating medicine and its prepn Download PDFInfo
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- CN1387872A CN1387872A CN 01114984 CN01114984A CN1387872A CN 1387872 A CN1387872 A CN 1387872A CN 01114984 CN01114984 CN 01114984 CN 01114984 A CN01114984 A CN 01114984A CN 1387872 A CN1387872 A CN 1387872A
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- rhizoma
- radix
- germinatus
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Abstract
The nephropathy treating medicine is prepared with 23 kinds of Chinese medicinal material including rhubarb, astragalus root, red sage, angelica, Chuanxiong rhizome, etc. The medicine of the present invention has the functions of invigorating spleen and kidney, softening the dry feces and dissipating mass, expelling toxic matter, removing necrosis and promoting granulation, protecting renal function and delaying renal failure.
Description
The present invention is a kind of medicine and processing method thereof for the treatment of nephropathy.
Nephropathy is a kind of commonly encountered diseases, and the cause of disease is not quite clear, it is generally acknowledged with immune relevant still do not have specific medicament at present.
The objective of the invention is to: the medicine and the processing method thereof that disclose a kind of effective treatment kidney disease.
Composition of the present invention and proportioning are: Radix Et Rhizoma Rhei 10～15g, the Radix Astragali 30～60g, Radix Salviae Miltiorrhizae 15～30g, Radix Angelicae Sinensis 10～20g, Rhizoma Chuanxiong 10～30g, Rhizoma Curcumae 10～20g, eupolyphaga 10～15g, process Squama Manis 10～15g, 3～6 of mole cricket aunts, 3～6 of CATHARSIUS, Endothelium corneum 10～20g, Fructus Hordei Germinatus 30～50g, Fructus Setariae Germinatus 30～50g, Fructus Oryzae Germinatus 30～50g, Semen Sinapis Albae 10～30g, Nodus Nelumbinis Rhizomatis 10～30g, Rhizoma Cyperi 10～20g, Rhizoma Acori Calami 10～20g, Sargassum 10～20g, Armadillidium 5～10g, Formica fusca 5～10g, the Radix Rehmanniae 30～50g, Radix Rehmanniae Preparata 30～50g.
In the present invention, Radix Astragali invigorating the spleen and benefiting QI; Living, Radix Rehmanniae Preparata enriching yin and nourishing kidney; Semen Sinapis Albae, Rhizoma Curcumae, Rhizoma Chuanxiong, Formica fusca, eupolyphaga, process Squama Manis, mole cricket aunt, CATHARSIUS, Endothelium corneum, Armadillidium hard masses softening and resolving, softening glomerule; Fructus Hordei Germinatus, Fructus Setariae Germinatus, all buds of Fructus Oryzae Germinatus are got the analogy picture, the hair growth promoting the kidney invigorating; Thing in Nodus Nelumbinis Rhizomatis, Rhizoma Cyperi, Rhizoma Acori Calami, the Sargassum water, water-fast antitoxin, vital energy regualting and blood circulation-promoting, dissipating blood stasis collateral dredging, activation glomerule; Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Radix Et Rhizoma Rhei cooling blood for hemostasis, promoting blood circulation to remove blood stasis, weed out the old and bring forth the new.All medicines share and play strengthening spleen, tonifying kidney, hard masses softening and resolving, detoxication and toxicant eliminating function, promoting tissue regeneration by removing blood stasis altogether, and renal function protecting delays the effect that renal failure makes progress, the patient that slows down enters end-stage renal failure speed.The traditional Chinese medical science thinks that chronic kidney hypofunction belongs to the card of vital QI being weakened and pathogen being violent, and it is weakened body resistance to be the internal organs deficient qi and blood, suffers from a deficiency of the kidney based on spleen especially and declines, and its domination of pathogen refers to the evil poison heap soil or fertilizer over and around the roots of turbid damp resistance.The rule of treatment is protected kidney qi with Gu, and protecting and taking the photograph negative and positive is basic principle, also should distinguish the primary and secondary emergency of specimen deficiency and excess simultaneously, strengthening vital QI to eliminate pathogenic factors, and treating both the principal and secondary aspects of a disease, symptomatic treatment in acute condition, relieving the primary symptom in a chronic case must not be abused and restrain the product that cut down in order to avoid damage kidney qi.The present invention has added the medicine of hard masses softening and resolving on this basis, in the hope of softening hardened glomerule; Add all buds and get the analogy picture and mend core (kidney), excite anger (machine), in the hope of the regeneration glomerule with core.Kidney is apparatus for treating sewage of picture in human body, and the present invention adds the thing multipotency antagonism sewage toxin in the water, with medicines such as Nodus Nelumbinis Rhizomatis, Rhizoma Acori Graminei, Sargassums in the hope of detoxication and toxicant eliminating function, renal function protecting.
Processing method of the present invention is: 1,80 mesh sieves are concocted and pulverized to eupolyphaga, Squama Manis, mole cricket aunt, CATHARSIUS, Endothelium corneum, Armadillidium, Formica fusca etc. according to the Chinese medicine concocting method.2, Rhizoma Curcumae, Rhizoma Chuanxiong power are broken into coarse powder, extract with alcohol percolation method.3, Fructus Hordei Germinatus, Fructus Setariae Germinatus, Fructus Oryzae Germinatus, Semen Sinapis Albae, little stir-fry and crushing screening generate medicinal residues.The medicinal residues of medicinal residues behind Rhizoma Curcumae, Rhizoma Chuanxiong percolation are with the other medicines decocting and be condensed into relative density to 1.20.4, concentrated solution+ethanol is made with extra care → supernatant recovery ethanol, and is condensed into clear paste, merges with Rhizoma Curcumae, Rhizoma Chuanxiong percolate.5, medicated powder → molding → extraction liquid flooding ball → drying → coating → polishing → packing.
In addition, according to prescription of the present invention, can also be processed as other dosage form according to conventional method.
Below in conjunction with embodiment the present invention is elaborated.
The processing method of following each embodiment is:
6, eupolyphaga, Squama Manis, mole cricket aunt, CATHARSIUS, Endothelium corneum, Armadillidium, Formica fusca etc. are according to Chinese medicine process of preparing Chinese medicine side
80 mesh sieves are concocted and pulverized to method.
7, Rhizoma Curcumae, Rhizoma Chuanxiong power are broken into coarse powder, extract with alcohol percolation method.
8, Fructus Hordei Germinatus, Fructus Setariae Germinatus, Fructus Oryzae Germinatus, Semen Sinapis Albae, little stir-fry and crushing screening generate medicinal residues.Medicinal residues and cowherb
Medicinal residues behind art, the Rhizoma Chuanxiong percolation are with the other medicines decocting and be condensed into relative density to 1.20.
9, concentrated solution+ethanol is made with extra care → supernatant recovery ethanol, and is condensed into clear paste, with Rhizoma Curcumae, river
The rhizome of chuanxiong percolate merges.
10, medicated powder → molding → extraction liquid flooding ball → drying → coating → polishing → packing.
Perhaps, according to prescription of the present invention, can also be processed as other dosage form according to conventional method, as decoction, pill, capsule etc.
| Embodiment | One | Two | Three | Four | Five | Six | Seven | Eight | Nine | Ten |
| Radix Et Rhizoma Rhei | 10 | ?11 | ?11.5 | ?12 | ?12.5 | ?13 | ?13.5 | ?14 | ?14.5 | ?15 |
| The Radix Astragali | 40 | ?45 | ?50 | ?30 | ?55 | ?35 | ?60 | ?58 | ?48 | ?38 |
| Radix Salviae Miltiorrhizae | 30 | ?20 | ?15 | ?28 | ?26 | ?17 | ?22 | ?24 | ?19 | ?16 |
| Radix Angelicae Sinensis | 15 | ?16 | ?11 | ?10 | ?13 | ?12 | ?14 | ?18 | ?20 | ?19 |
| Rhizoma Chuanxiong | 10 | ?14 | ?16 | ?18 | ?20 | ?22 | ?24 | ?26 | ?28 | ?30 |
| Rhizoma Curcumae | 20 | ?19 | ?18 | ?17 | ?16 | ?15 | ?14 | ?13 | ?12 | ?10 |
| Eupolyphaga | 10 | ?10.5 | ?11 | ?11.5 | ?12 | ?12.5 | ?13 | ?13.5 | ?14 | ?15 |
| Process Squama Manis | 12 | ?12.5 | ?15 | ?14 | ?13.5 | ?11 | ?10 | ?14.5 | ?11.5 | ?13 |
| Mole cricket aunt (individual) | 3 | ?5 | ?4 | ?3 | ?5 | ?4 | ?3 | ?6 | ?4 | ?6 |
| CATHARSIUS (individual) | 5 | ?4 | ?6 | ?5 | ?3 | ?4 | ?5 | ?6 | ?3 | ?4 |
| Endothelium corneum | 10 | ?13 | ?15 | ?12 | ?17 | ?18 | ?16 | ?11 | ?14 | ?20 |
| Fructus Hordei Germinatus | 40 | ?32 | ?43 | ?30 | ?45 | ?50 | ?45 | ?35 | ?48 | ?38 |
| Fructus Setariae Germinatus | 45 | ?35 | ?38 | ?48 | ?30 | ?50 | ?42 | ?32 | ?46 | ?34 |
| Fructus Oryzae Germinatus | 30 | ?42 | ?32 | ?46 | ?36 | ?44 | ?38 | ?48 | ?50 | ?40 |
| Semen Sinapis Albae | 12 | ?20 | ?18 | ?10 | ?22 | ?16 | ?24 | ?14 | ?28 | ?30 |
| Nodus Nelumbinis Rhizomatis | 18 | ?10 | ?20 | ?12 | ?22 | ?14 | ?30 | ?16 | ?24 | ?28 |
| Rhizoma Cyperi | 10 | ?14 | ?15 | ?17 | ?13 | ?18 | ?11 | ?16 | ?20 | ?12 |
| Rhizoma Acori Calami | 12 | ?16 | ?14 | ?15 | ?11 | ?17 | ?13 | ?19 | ?10 | ?20 |
| Sargassum | 14 | ?12 | ?16 | ?10 | ?20 | ?13 | ?15 | ?11 | ?17 | ?18 |
| Armadillidium | 6 | ?7 | ?5 | ?6.5 | ?7.5 | ?9 | ?8.5 | ?5.5 | ?10 | ?8 |
| Formica fusca | 8 | ?5.5 | ?7 | ?8.5 | ?6.5 | ?10 | ?5 | ?7.5 | ?6 | ?9 |
| The Radix Rehmanniae | 30 | ?38 | ?48 | ?32 | ?42 | ?40 | ?34 | ?50 | ?46 | ?36 |
| Radix Rehmanniae Preparata | 36 | ?40 | ?30 | ?44 | ?34 | ?42 | ?38 | ?48 | ?32 | ?50 |
The Ceng Fanzong man, 60 years old.Early stage uremia 1 year, a nephrectomy, the treatment of coming on October 30th, 2000.Side of the present invention for oral administration is after 40 days, and serum creatinine is reduced to 185 micromoles per liter by 400.The patient is normal substantially at present, continues to strengthen treatment.
The Li Baoqing man, 30 years old.On December 20th, 1998: flu anasarca first quarter moon, invalid and change the county hospital hospitalization over to through the diagnosis and treatment of local commune hospital, during to give Drug therapy such as diuretic antihypertensive invalid, Cr532mmol/l has a blood test, then transfer treatment, examine on inspection and be " renal failure ", Fang Yizhou of the present invention for oral administration, edema disappears, continue with medicine-feeding treatment first quarter moon check blood Cr106mmol/l, diet is normal, follows up a case by regular visits to so far, disease is not sent out, and can be engaged in operate as normal.
Wang Rui lotus woman, 60 years old.First visit on January 18 in 1999: edema is 3 years repeatedly, urine protein (+++), occult blood (+++), blood Cr299 μ mol/l, BUN11.2mmol/l, Hb98g/l, ultrasonic diagnosis: 1. pair kidney diffuse lesion ultrasonogram (right kidney 87 * 38mm, left kidney 91 * 44mm); 2. excess of the kidney matter Intramedullary Cysts and calcification examined and is " chronic renal failure (azotemia phase) ", takes 30 doses of sides of the present invention (day 1 dose), check blood Cr99 μ mol/l, BUN5.1mmol/l, urine Rt (-).Follow up a case by regular visits to (January 4 calendar year 2001) so far, stable disease (can be engaged in light physical labor, repeatedly check BUN, Cr is normal).
Zhao Chun sesame woman, 38 years old.First visit in February 21 in 1999: hematuria is 2 years repeatedly.Once it is invalid to arrive the diagnosis and treatment of how tame medical institutions.Look into: blood Cr267.9 μ mol/l, BUN12.69mmol/l, ultrasonic diagnosis: two renal function severes are impaired, and (right kidney 8.7 * 4.3cm, left kidney 8.4 * 4.3cm) are examined and are " chronic renal failure (azotemia phase) ".After taking 90 doses of sides of the present invention (1 dose of day), check blood Cr151.4 μ mol/l, BUN7.38mmol/l.Follow up a case by regular visits to so far stable disease.
Wang You gives birth to man, 60 years old.First visit on May 4 in 1999: weak, the nauseating prescription on individual diagnosis in 146 hospitals of PLA.Look into: blood Cr531 μ mol/l, BUN20.82mmol/l, CO2 CP11mmol/l, examine and be " chronic renal failure (azotemia phase) ", hospitalization is imitated and show March, after take 36 doses of sides of the present invention (day 1 dose) after, check blood Cr389.1 μ mol/l, BUN23.46mmol/l.Imitate more not square, 30 doses of the sides of the present invention of clothes that continue, it is normal that Cr, BUN recover.Follow up a case by regular visits to so far stable disease.
Claims (2)
1, a kind of medicine for the treatment of nephropathy is characterized in that: its composition and proportioning are: Radix Et Rhizoma Rhei 10～15g, the Radix Astragali 30～60g, Radix Salviae Miltiorrhizae 15～30g, Radix Angelicae Sinensis 10～20g, Rhizoma Chuanxiong 10～30g, Rhizoma Curcumae 10～20g, eupolyphaga 10～15g, process Squama Manis 10～15g, 3～6 of mole cricket aunts, 3～6 of CATHARSIUS, Endothelium corneum 10～20g, Fructus Hordei Germinatus 30～50g, Fructus Setariae Germinatus 30～50g, Fructus Oryzae Germinatus 30～50g, Semen Sinapis Albae 10～30g, Nodus Nelumbinis Rhizomatis 10～30g, Rhizoma Cyperi 10～20g, Rhizoma Acori Calami 10～20g, Sargassum 10～20g, Armadillidium 5～10g, Formica fusca 5～10g, the Radix Rehmanniae 30～50g, Radix Rehmanniae Preparata 30～50g.
2, the medicine processing method of treatment nephropathy, it is characterized in that: 80 mesh sieves are concocted and pulverized to (1) eupolyphaga, Squama Manis, mole cricket aunt, CATHARSIUS, Endothelium corneum, Armadillidium, Formica fusca etc. according to the Chinese medicine concocting method; (2) Rhizoma Curcumae, Rhizoma Chuanxiong power are broken into coarse powder, extract with alcohol percolation method; (3) Fructus Hordei Germinatus, Fructus Setariae Germinatus, Fructus Oryzae Germinatus, Semen Sinapis Albae, little stir-fry and crushing screening generate medicinal residues.The medicinal residues of medicinal residues behind Rhizoma Curcumae, Rhizoma Chuanxiong percolation are with the other medicines decocting and be condensed into relative density to 1.20; (4) concentrated solution+ethanol is refining, and supernatant reclaims ethanol, and is condensed into clear paste, merges with Rhizoma Curcumae, Rhizoma Chuanxiong percolate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01114984 CN1387872A (en) | 2001-05-25 | 2001-05-25 | Nephropathy treating medicine and its prepn |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01114984 CN1387872A (en) | 2001-05-25 | 2001-05-25 | Nephropathy treating medicine and its prepn |
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| Publication Number | Publication Date |
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| CN1387872A true CN1387872A (en) | 2003-01-01 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 01114984 Pending CN1387872A (en) | 2001-05-25 | 2001-05-25 | Nephropathy treating medicine and its prepn |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1325094C (en) * | 2004-04-14 | 2007-07-11 | 张鸣鸣 | Medicine for treating uaemia and insufficiency of kidney-yang and kidney exhaustion and its preparing method |
| CN100349583C (en) * | 2004-01-13 | 2007-11-21 | 合肥恒星药物研究所 | Chinese traditional medicine for treating chronic nephritis |
| CN101099809B (en) * | 2007-07-20 | 2010-10-06 | 昆明禾润药物开发有限公司 | Drug for curing kidney disease and its preparing method |
-
2001
- 2001-05-25 CN CN 01114984 patent/CN1387872A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100349583C (en) * | 2004-01-13 | 2007-11-21 | 合肥恒星药物研究所 | Chinese traditional medicine for treating chronic nephritis |
| CN1325094C (en) * | 2004-04-14 | 2007-07-11 | 张鸣鸣 | Medicine for treating uaemia and insufficiency of kidney-yang and kidney exhaustion and its preparing method |
| CN101099809B (en) * | 2007-07-20 | 2010-10-06 | 昆明禾润药物开发有限公司 | Drug for curing kidney disease and its preparing method |
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