CN1381251A - Ointment for treating burn and scald and its preparing process - Google Patents
Ointment for treating burn and scald and its preparing process Download PDFInfo
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- CN1381251A CN1381251A CN 02108919 CN02108919A CN1381251A CN 1381251 A CN1381251 A CN 1381251A CN 02108919 CN02108919 CN 02108919 CN 02108919 A CN02108919 A CN 02108919A CN 1381251 A CN1381251 A CN 1381251A
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- borneolum syntheticum
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Abstract
An ointment for treating burn and scald is prepared from 8 Chinese medicinal materials including liquoice root, bletilla tuber, Chinese gall, arnebia root, etc. through extracting in animal oil at 150-300 deg.C for 15 min-2 hr, filtering to remove dregs and cooling. Its advantages are quickly healing and short course of treatment (7-14 days).
Description
Technical field
The present invention relates to medicinal preparation, skin preparation particularly belongs to that active ingredient comes from the material of plant and is the unguentum of carrier with the oils and fats.
Background technology
China's Chinese medicinal formulae and folk prescription that many treatment burns are arranged among the people.These efficacious agents are broadly divided into two classes from the form of medicine: a class be Chinese medicine is ground (or smashing) broken, directly be coated in the affected part, spread on the affected part as mashing with Lumbricus, Folium Camelliae sinensis, Herba Houttuyniae, Folium Nelumbinis; And for example be ground into the end and apply the affected part, for facet burn effective (Guo Shouying etc. " little folk prescription is controlled all kinds of diseases and ailments " Jilin science and technology publishing house, version in 1993 1.) with Calomelas, Borneolum Syntheticum, dried Alumen.It is that the preparation of monarch drug also has suitable effect with the Gypsum Fibrosum that this class also has multiple, in gauze bag that the Gypsum Fibrosum powder of parch is packed into, being sprinkling upon has good effect (Zhang Nianshun " angle's odd-prescription 999 " China Traditional Chinese Medicine Publishing House, version in 1997 2.) on the wound surface of wiping out beancurd sheet and disinfectant burn.Though this class medicament is being imitated, owing to do not have oils and fats or other can moisten subsides to skin, makes medicine directly contact wound surface, and easily produces hard crust, patient's pain is very strong, and this is very painful.Another kind of is to contain Mel, egg, Oleum Sesami, Oleum Verniciae fordii, Cera Flava etc. in the medicament, and this class prescription is a lot, such as in 1. act Radix Arnebiae (Radix Lithospermi), Pericarpium Granati, Herba Pteridis Multifidae, Folium Mori, Herba Taraxaci, modulate with egg; Useful again Radix Et Rhizoma Rhei, Radix Scutellariae, Cortex Phellodendri, cold BINGSHI, Radix Sanguisorbae are modulated with vegetable oil; And for example 2. middle act is modulated with honey with tongue, Folium Luffae in Radix seu folium abelmoschi moschati flower, Radix Et Rhizoma Rhei, Talcum, Herba Artemisiae Anomalae, the well.In CN1205883A, be modulated into cream with Oleum Sesami, claim its curative effect height, short treating period, but do not see the treatment example with purple list, Flos Carthami with after Auricularia (or Tremella) bakes into charcoal.CN1207318A then selects 13 kinds of Chinese medicines and ripe egg yolks such as Radix Sanguisorbae, Cortex Phellodendri, Radix Et Rhizoma Rhei for use, form with the Oleum Sesami modulation, show in the clinical efficacy statistics that the average recovery from illness of shallow two degree is 8.5～10 days, and dark two degree are 17.5～20 days, shallow, dark tridimensional average recovery from illness is all more than 26 days.The data that prior art does not all relieve the pain are the most urgent requirements of burn patient and stop pain as early as possible.In addition, all existing medicaments are except that with nearly all using Vegetable oil lipoprotein as carrier egg, honey, the wax, though this carrier can lubricate skin, prevent dry and cracked, guide drugs treatment wound face, but the affinity of itself and people's skin is relatively poor, it is limited to enter skin nexine usefulness, thereby relieves the pain and to treat the effect of wound surface still undesirable.
Summary of the invention
At the deficiency that the above prior art exists, the purpose of this invention is to provide a kind of ointment that relieves the pain faster with the better healing effect that burn is had.
Chinese prescription of the present invention (weight %) is:
Radix Glycyrrhizae 50～85
Pseudobulbus Bletillae (Rhizoma Bletillae) 5～20
Galla Chinensis 1～10
Radix Arnebiae (Radix Lithospermi) 1～10
Shrubalthea Bark 5～20
Caulis Lonicerae (vine of Flos Lonicerae) 0～5
Folium Nelumbinis 0～5
Borneolum Syntheticum 0.5～5.0 used carrier is an animal oil, is 90～100% Adeps Sus domestica and 0～10% lanoline.The method for making of ointment is: the weight proportion of Chinese medicine and animal oil is
Chinese medicine: animal oil=1: 1～3 elder generations in vessel in heating, immerse oils and fats respectively in 15min～2.0h between 150～300 ℃ and extract with Chinese medicine, filter to remove medicinal residues, cool off.In practice, following Chinese medicine preparation is more suitable, and single Adeps Sus domestica extraction of using:
Radix Glycyrrhizae 60～75%
Pseudobulbus Bletillae (Rhizoma Bletillae) 10～15%
Galla Chinensis 2～8%
Radix Arnebiae (Radix Lithospermi) 1～5%
Shrubalthea Bark 10～15%
Caulis Lonicerae 1～3%
Borneolum Syntheticum 0.5～2.0% is about using the lixiviate of animal hot grease, easily burnt the paste or evaporation when Radix Arnebiae (Radix Lithospermi), Borneolum Syntheticum and Folium Nelumbinis extract in deep fat, so it is should temperature low slightly or the time short, so that it becomes the sallow and non-burnt degree that is in hot grease.
This ointment that makes, thicker can not flowing under the room temperature, color is light red, pale purple or shallow reddish brown, and the denseer taste of Chinese medicine that has animal oil is arranged.Being applied to promptly has cool sense on the skin, the wound face pain alleviates gradually, to disappearing.
It is monarch drug that the present invention selects Radix Glycyrrhizae for use, is because it has stronger pathogenic fire purging pain relieving, the function of detoxification of relieving inflammation or internal heat, and " in all medicines be monarch with the Radix Glycyrrhizae, the function coordinating the actions of various ingredients in a prescription has the old title of state then " in the own function of performance, coordinated other drug and played a role jointly.It is very rare in existing hospital that Radix Glycyrrhizae is used for burn, and then more rare as monarch drug.Pseudobulbus Bletillae (Rhizoma Bletillae) has another name called Rhizoma Bletillae, indocalamus orchid, hemostasis is arranged, promote growth of wound surface granulation and the effect of healing.This medicine is the principal agent of the long skin of granulation promoting in the medicine of the present invention.In addition, gallic function is hemostasis; The clearing away damp-heat of Shrubalthea Bark, and the heat-clearing and toxic substances removing of Radix Ophiopogonis, quench heat, the removing heat from blood and promoting blood circulation of Radix Arnebiae (Radix Lithospermi), heat-clearing and toxic substances removing; The heat clearing away of the Borneolum Syntheticum toxic swelling that relieves the pain, dissipates; The function of the removing stasis to stop bleeding of Folium Nelumbinis plays the composition of medicine assistant, makes effect.The present invention comes out the extracts active ingredients of above-mentioned Chinese crude drug with animal oil, becomes the oil-soluble one, has avoided as the stimulation of Chinese medicinal granule in the prior art to wound face.Effective Components of Chinese Herb together with the synergism of animal oil, plays pain relieving, detumescence, antiinflammatory, heat clearing away and internal heat reducing, remuval of damp and hot, skin moistening, and granulation promoting afterwards, long skin and healing wounds face to the wound surface and the deep tissues thereof of burn skin.The most outstanding is: the position of burn 15～30min after coating ointment of the present invention promptly plays the pain relieving effect, this be the prior art difficulty by comparison.Because as carrier, it now has more affinity with carrier and skin histology than vegetable oil and other with animal oil; The fat extract that this medium band medicine is not only launched rapidly at wound surface, and skin surface is played skin moistening and therapeutical effect, and can infiltrate subcutaneous even deep tissues is treated.This solid, comprehensive therapeutical effect can make the wounded relieve the pain rapidly and shorten healing time.Therefore ointment of the present invention burns, scalds at 7～14 days and can fully recover one, two degree small sizes, can heal at 1 wheat harvesting period even reach the small-area burn of 8～10mm deeply, and skin-grafting can not recover the sweat gland function yet.Ointment of the present invention is not only effective to common burn, and also effective in cure to flash burn, chemical burn.In addition, the therapeutical effect that chilblain and other wound skin is also had good removing the necrotic tissue and promoting granulation.To small size (30cm
2Below) as long as in time handling cure rate, burn reaches 100%; Burn, scald and cure dark two degree of large tracts of land are above also more than 98%.
The invention provides a new prescription that solves treatment burn medicine.Use Radix Glycyrrhizae, Pseudobulbus Bletillae (Rhizoma Bletillae) etc. as main medicine, and be carrier, under the other drug synergism, can obtain quick pain relief and quite high curative effect with animal oil.In addition, the active ingredient of animal oil heat extraction medicine is also rarely found.Especially the fat extract of the drug component in the present invention's prescription can become one mutually with oils and fats, can effectively treat skin and deep tissues, and this also is one of characteristics of the present invention.
The specific embodiment
Example 1
The preparation of burn ointment.Herbal species and quantity (kg) are
Radix Glycyrrhizae 0.55 Pseudobulbus Bletillae (Rhizoma Bletillae) 0.15 Galla Chinensis 0.07
Shrubalthea Bark 0.05 Caulis Lonicerae 0.05 Radix Arnebiae (Radix Lithospermi) 0.05
Borneolum Syntheticum 0.03 Folium Nelumbinis 0.05
Animal oil is with Adeps Sus domestica (being smelt by leaf fat) and the 0.2kg lanoline of 1.8kg.
Ointment is fabricated to: with Adeps Sus domestica and lanoline at the container internal heating, the oil temperature successively is lowered to Radix Glycyrrhizae, Pseudobulbus Bletillae (Rhizoma Bletillae), Galla Chinensis, Shrubalthea Bark, Caulis Lonicerae, Borneolum Syntheticum in the deep fat when reaching 200 ℃, temperature is no more than 220 ℃ around here, when slowly lowering the temperature Radix Arnebiae (Radix Lithospermi) and Folium Nelumbinis are added, be advisable with non-burnt, cooling promptly condenses into cream after removing by filter medicinal residues.Ointment is pale red, has during news strand to be with greasy taste of Chinese medicine, and contact skin has refrigerant sense.
Example 2
The preparation of burn ointment.Herbal species and consumption (kg)
Radix Glycyrrhizae 0.75 Pseudobulbus Bletillae (Rhizoma Bletillae) 0.05 Galla Chinensis 0.02
Shrubalthea Bark 0.10 Caulis Lonicerae 0.01 Radix Arnebiae (Radix Lithospermi) 0.02
Borneolum Syntheticum 0.05 usefulness 3kg Adeps Sus domestica is carrier, and heating adds medicine respectively at 220～250 ℃ and to extract, exceed so that medicine is non-burnt, and cooling, the filtering medicinal residues are cooled to room temperature and condense into cream.
Example 3
Ointment is made Chinese medicine and carrier consumption (kg) is
Radix Glycyrrhizae 0.80 Pseudobulbus Bletillae (Rhizoma Bletillae) 0.10 Galla Chinensis 0.03
Shrubalthea Bark 0.05 Radix Arnebiae (Radix Lithospermi) 0.015 Borneolum Syntheticum 0.005
Adeps Sus domestica 1.5
Method for making such as example 2.
Example 4
The ointment curative effect:
(1) the model case clinical efficacy is taken passages:
1. high * *, the cadre, left hand steam is scalded, and about 20cm2 smears with edible soy sauce immediately, and pain increases the weight of.Rinse well with tap water the back, is coated with above-mentioned example 1 ointment, exposed; Pain relief is also painless then behind the 15min, and there is cool sense the injury beginning, and recovery from illness on the 7th does not have the scar of staying so far.
2. Rhizoma Zingiberis Recens * *, 6 years old child, boiled water is scalded lower limb, foot, is shallow to dark 2 degree, the big vesicle bunchiness of affected part when being hospitalized for treatment.Discharge water to cut off blister, detoxicating, medical sulfanilamide ointment for scald applies it, is that gnawing pains take no rest, after use the deposited 15min pain relief of example 2 ointment instead and do not cry gradually, 30min had both desired to play, first quarter moon more.
3. grandson * *, certain gas welder of steel mill, oxygen hose burns broken when freezing, oxygen and tempering make its right hand palm burn dark 8～10mm hole that reaches, and its severe pain is applied it with ointment of the present invention unbearably, pain is ended behind the 30min, the moon is surplus more, skin-grafting, and palm is long flat, over follow-up investigation, say that injured palm is as usual, can perspire, prove sweat gland restore funcitons.
4. stone * *, the electric welder of building constructor, the electric arc burn right hand, outpatient service is cured and to be healed for a long time and not, use-case 3 ointment 7 days more.
5. beam * *, certain iron company ore dressing plant, shirtfront, two arm petrol burn are dark 2 degree～3 degree, it is month surplus to be hospitalized for treatment, spend 20,000 surplus yuan, the conventional medicine effect is inaccurate, cicatrix more, is not stayed so far with ointment first quarter moon of the present invention in the back.
(1) clinical application for many years statistics:
Over 100 years, treat over thousands of example, in the majority with burn especially.Statistical number such as following table.
| The burn degree of depth and area | Analgesic time min | The cure time sky | Cure rate % |
| One～shallow two degree 30cm 2Following 300cm 2Below shallow two～shallow three degree 30cm 2Following 300cm 2Below dark two～dark three degree 30cm 2Below | ????15～20 ????15～20 ????20～30 ????20～30 ????20～30 | ????7～10 ????7～10 ????10～20 ????10～20 ????15～40 | ?????100％ ?????100％ ?????100％ ?????99％※ ???????????99％※ |
※ continues in time, and the patient is out of touch, and a example that can't follow-up investigation is also added up therein.
Claims (4)
1, a kind of treatment burn external Chinese medicine ointment, it is characterized in that ointment is pale purple, light red or light brown red, the Chinese medicine abnormal smells from the patient that has animal oil, be that Chinese crude drug is made with animal oil hot dipping extraction, contain the animal oil heat extraction substrate by following Chinese crude drug of 1 weight portion in the ointment of per 1～3 weight portion; Herbal species and weight percent consist of:
Radix Glycyrrhizae 50～85
Pseudobulbus Bletillae (Rhizoma Bletillae) 5～20
Galla Chinensis 1～10
Shrubalthea Bark 5～20
Radix Arnebiae (Radix Lithospermi) 1～10
Caulis Lonicerae 0～5
Folium Nelumbinis 0～5
Borneolum Syntheticum 0.5～5.0 animal oil is 90～100% Adeps Sus domesticas, 0～10% lanoline.
2, Chinese medicine ointment according to claim 1, its herbal species and weight percent consist of when it is characterized in that described animal oil heat is extracted Chinese medicine:
Radix Glycyrrhizae 60～75
Pseudobulbus Bletillae (Rhizoma Bletillae) 10～15
Galla Chinensis 2～8
Shrubalthea Bark 10～15
Radix Arnebiae (Radix Lithospermi) 1～5
Caulis Lonicerae 1～3
Borneolum Syntheticum 0.5～2.0 animal oil is an Adeps Sus domestica.
3, the method for making of Chinese medicine ointment according to claim 1 is characterized in that the weight percent proportioning of Chinese medicine is:
Radix Glycyrrhizae 50～85
Pseudobulbus Bletillae (Rhizoma Bletillae) 5～20
Galla Chinensis 1～10
Shrubalthea Bark 5～20
Radix Arnebiae (Radix Lithospermi) 1～10
Caulis Lonicerae 0～5
Folium Nelumbinis 0～5
Borneolum Syntheticum 0.5～5.0 animal oil is 90～100% Adeps Sus domesticas, 0～10% lanoline; Its processing technology is: animal oil in vessel in heating, immerse extracted Chinese medicine respectively in 15min～2.0h between 150～300 ℃, and filtering medicinal residues then, cooling.
4, the method for making of Chinese medicine ointment as claimed in claim 3 is characterized in that Borneolum Syntheticum, Radix Arnebiae (Radix Lithospermi), Folium Nelumbinis, adds at last in the hot grease, makes it non-burnt for spending in hot grease.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021089191A CN1156301C (en) | 2002-04-04 | 2002-04-04 | Ointment for treating burn and scald and its preparing process |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021089191A CN1156301C (en) | 2002-04-04 | 2002-04-04 | Ointment for treating burn and scald and its preparing process |
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| Publication Number | Publication Date |
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| CN1381251A true CN1381251A (en) | 2002-11-27 |
| CN1156301C CN1156301C (en) | 2004-07-07 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102429986A (en) * | 2010-09-29 | 2012-05-02 | 董析颖 | Traditional Chinese ointment for treating burn and scald and preparation method thereof |
| CN102940870A (en) * | 2012-12-06 | 2013-02-27 | 郑松林 | Chinese medicinal composition for treating burns and scalds |
| CN103446442A (en) * | 2013-08-28 | 2013-12-18 | 黎英豪 | Ointment for treating burn and preparation method thereof |
| CN104940909A (en) * | 2015-06-30 | 2015-09-30 | 桂林华诺威基因药业有限公司 | Unguent for treating empyrosis and preparation method thereof |
-
2002
- 2002-04-04 CN CNB021089191A patent/CN1156301C/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102429986A (en) * | 2010-09-29 | 2012-05-02 | 董析颖 | Traditional Chinese ointment for treating burn and scald and preparation method thereof |
| CN102429986B (en) * | 2010-09-29 | 2013-10-16 | 董析颖 | Traditional Chinese ointment for treating burn and scald and preparation method thereof |
| CN102940870A (en) * | 2012-12-06 | 2013-02-27 | 郑松林 | Chinese medicinal composition for treating burns and scalds |
| CN103446442A (en) * | 2013-08-28 | 2013-12-18 | 黎英豪 | Ointment for treating burn and preparation method thereof |
| CN104940909A (en) * | 2015-06-30 | 2015-09-30 | 桂林华诺威基因药业有限公司 | Unguent for treating empyrosis and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN1156301C (en) | 2004-07-07 |
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