CN1342456A - Process for preparing medicine to prevent and cure diabetes, hyperlipomia and obesity - Google Patents
Process for preparing medicine to prevent and cure diabetes, hyperlipomia and obesity Download PDFInfo
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- CN1342456A CN1342456A CN 01128939 CN01128939A CN1342456A CN 1342456 A CN1342456 A CN 1342456A CN 01128939 CN01128939 CN 01128939 CN 01128939 A CN01128939 A CN 01128939A CN 1342456 A CN1342456 A CN 1342456A
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- starch
- lubricant
- obesity
- filler
- diabetes
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Abstract
A process for preparing the medicine to prevent and treat diabetes, hyperlipomia and obesity includes such steps as proportionally mixing chronmium aminoacitate with filler, disintegrant, lubricant and adhesive and conventionally preparing tablets, particles or capsules. The filler may be starch, emulsified starch, amyline, etc.. The disintegrant may be cross-linked carboxymethylcellulose sodium, starch, etc. The lubricant may be magnesium stearate, talc powder, etc. The adhesive may be starch paste, gelatin or arabic gum, etc. Its advantages are simple preparing process and high curative effect.
Description
The invention belongs to the preparation field of medicine, specifically is a kind of compound method of preventing and treating the medicine of diabetes, hyperlipemia and obesity.
Diabetes, hyperlipemia and obesity are higher several diseases of sickness rate in recent years, and along with the raising of people's living standard, its sickness rate becomes ascendant trend, and old people's above-mentioned disease that is easy to get not only, and the youngster sickness rate is also increasing.Though treat in recent years above-mentioned disease in, Western medicine appears on the market one after another like rain the back spring bamboo, still has many knotty problems to need people to go to solve, and continually develops and prevents and treats diabetes, the newtype drug of hyperlipemia and obesity is still the key subjects of pendulum in face of people.
The objective of the invention is for people by a kind of compound method of the novel medicine of preventing and treating diabetes, hyperlipemia and obesity is provided, preparation technology is simple for this method, the product good effect.
The objective of the invention is to realize by following technical proposals.
Preparation method of preventing and treating the medicine of diabetes, hyperlipemia and obesity of the present invention; be that chromium glycine (trivalent) is mixed with filler, disintegrating agent, lubricant, binding agent; adopt general pharmaceutical technology to be made into tablet, granule or capsule; above-mentioned chromium glycine: filler: disintegrating agent: the weight ratio of lubricant is 0.5～10: 100～400: 5～15: 0.2～1, add an amount of binding agent again.
Above-mentioned filler is starch, latex starch, dextrin, microcrystalline Cellulose, mannitol, disintegrating agent is crosslinked Carboxymethyl cellulose sodium, polyvinylpolypyrrolidone, carboxymethyl starch sodium, starch, lubricant is magnesium stearate, Pulvis Talci, liquid Paraffin, and binding agent is starch slurry, polyvidone, gelatin or arabic gum, hypromellose.It can be the compositions of any one or two kinds in above-mentioned filler, disintegrating agent, lubricant, the binding agent.
In the above-mentioned component, trivalent chromic ion is one of necessary micronutrient element of human body, the main metabolic process that participates in keeping normal carbohydrate and lipid.If in daily meals, lack essential chromium (III), the sugar in the blood then may occur, insulin, cholesterol, the rising of triglyceride concentration and the reduction of high density lipoprotein; If symptoms such as a neural brain dysfunction then may appear in chromium (III) wretched insufficiency, above-mentioned symptom all can obtain reversing because of replenishing an amount of chromium (III).Technique scheme of the present invention is the scientific formula that the inventor sums up out by long-term practice; with chromium glycine (trivalent) and filler, disintegrating agent, lubricant, the collocation of binding agent science; adopt general pharmaceutical technology to be made into tablet, granule or capsule; be used to prevent and treat the medicine of diabetes, hyperlipemia and obesity, can reach the good effect of preventing and curing diseases.
The invention is further illustrated by the following examples, and the present invention is not limited only to described embodiment.
Embodiment one
Composition weight
Chromium glycine 2g
Starch 300g
Pulvis Talci 10g
Liquid Paraffin 0.2g
Starch slurry (being made into 17% aqueous solution) is an amount of
With the abundant mixing of above-mentioned each component, drop into boiling and make routine equipment, mixing, pelletize, drying are once finished; The granule that makes is used suitable packing, make A: granule; Or B: carry out tabletting and make tablet; Or C: load into capsule.
Embodiment two
Composition weight
Chromium glycine 5g
Microcrystalline Cellulose 200g
Magnesium stearate 0.8g
Crosslinked Carboxymethyl cellulose sodium 10g
Hypromellose 3g
With the abundant mixing of above-mentioned each component, make routine equipment, mixing, pelletize, drying by the boiling of current techique input; The granule that makes is used suitable packing, make A: granule; Or B: carry out tabletting and make tablet; Or C: load into capsule.
Embodiment three
Composition weight
Chromium glycine 6g
Dextrin 250g
Polyvinylpolypyrrolidone 8g
Liquid Paraffin 0.4g
Starch slurry (being made into 17% aqueous solution) is an amount of
With the abundant mixing of above-mentioned each component, drop into boiling and make routine equipment, mixing, pelletize, drying are once finished; The granule that makes is used suitable packing, make A: granule; Or B: carry out tabletting and make tablet; Or C: load into capsule.
Embodiment four
Composition weight
Chromium glycine 10g
Starch 400g
Sodium Hydroxymethyl Stalcs 10g
Pulvis Talci 0.6g
Gelatin is an amount of
With the abundant mixing of above-mentioned each component, drop into boiling and make routine equipment, mixing, pelletize, drying are once finished; The granule that makes is used suitable packing, make A: granule; Or B: carry out tabletting and make tablet; Or C: load into capsule.
Claims (3)
1, a kind of compound method of preventing and treating the medicine of diabetes, hyperlipemia and obesity; it is characterized in that it being that chromium glycine (trivalent) is mixed with filler, disintegrating agent, lubricant, binding agent; adopt general pharmaceutical technology to be made into tablet, granule or capsule; above-mentioned chromium glycine: filler: disintegrating agent: the weight ratio of lubricant is 0.5～10: 100～400: 5～15: 0.2～1, and binding agent is an amount of.
2, compound method of preventing and treating the medicine of diabetes, hyperlipemia and obesity according to claim 1, it is characterized in that described filler is starch, latex starch, dextrin, microcrystalline Cellulose, mannitol, disintegrating agent is cross-linking sodium carboxymethyl cellulose, polyvinylpolypyrrolidone, carboxymethyl starch sodium, starch, lubricant is magnesium stearate, Pulvis Talci, liquid Paraffin, binding agent is starch slurry, polyvidone, gelatin or arabic gum, hypromellose, is the compositions of any one or two kinds in above-mentioned filler, disintegrating agent, lubricant, the binding agent.
3, the product of the compound method gained of the medicine of preventing and treating diabetes, hyperlipemia and obesity according to claim 1 and 2 is used to prevent and treat diabetes, hyperlipemia and obesity, each phase of the sub-clinical state of above-mentioned disease and disease and complication.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011289392A CN1186017C (en) | 2001-10-09 | 2001-10-09 | Process for preparing medicine to prevent and cure diabetes, hyperlipomia and obesity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011289392A CN1186017C (en) | 2001-10-09 | 2001-10-09 | Process for preparing medicine to prevent and cure diabetes, hyperlipomia and obesity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1342456A true CN1342456A (en) | 2002-04-03 |
| CN1186017C CN1186017C (en) | 2005-01-26 |
Family
ID=4668748
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB011289392A Expired - Fee Related CN1186017C (en) | 2001-10-09 | 2001-10-09 | Process for preparing medicine to prevent and cure diabetes, hyperlipomia and obesity |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1186017C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003057244A3 (en) * | 2002-01-08 | 2003-12-18 | Amylin Pharmaceuticals Inc | Use of amylin agonists to modulate triglycerides |
| CN100348229C (en) * | 2005-09-26 | 2007-11-14 | 浙江泰利森药业有限公司 | Capsule prepn for treating laryngopharyngitis and tonsillitis and its prepn process |
| WO2007121312A3 (en) * | 2006-04-12 | 2008-05-15 | Interhealth Nutraceuticals Inc | Trivalent chromium compounds, compositions and methods of use |
| CN100453116C (en) * | 2004-10-19 | 2009-01-21 | 上海中西制药有限公司 | Process for preparing compound aminophylline tablet |
-
2001
- 2001-10-09 CN CNB011289392A patent/CN1186017C/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003057244A3 (en) * | 2002-01-08 | 2003-12-18 | Amylin Pharmaceuticals Inc | Use of amylin agonists to modulate triglycerides |
| CN100453116C (en) * | 2004-10-19 | 2009-01-21 | 上海中西制药有限公司 | Process for preparing compound aminophylline tablet |
| CN100348229C (en) * | 2005-09-26 | 2007-11-14 | 浙江泰利森药业有限公司 | Capsule prepn for treating laryngopharyngitis and tonsillitis and its prepn process |
| WO2007121312A3 (en) * | 2006-04-12 | 2008-05-15 | Interhealth Nutraceuticals Inc | Trivalent chromium compounds, compositions and methods of use |
| US9700546B2 (en) | 2006-04-12 | 2017-07-11 | Interhealth Nutraceuticals, Inc. | Trivalent chromium compounds, compositions and methods of use |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1186017C (en) | 2005-01-26 |
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| C14 | Grant of patent or utility model | ||
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| CF01 | Termination of patent right due to non-payment of annual fee |