CN1331986A

CN1331986A - Genetic medicine product prepared with edible fungi and Chinese medicine material and its prepn technology

Info

Publication number: CN1331986A
Application number: CN 01109668
Authority: CN
Inventors: 萧河龙
Original assignee: Individual
Current assignee: Individual
Priority date: 2001-03-16
Filing date: 2001-03-16
Publication date: 2002-01-23

Abstract

The present invention combines traditional Chinese medicine theory and modern genetic medicine and pharmacology. The senility of human body is controlled by gene. The medicine for delaying senility of the present invention can affect DNA telomerase and positive to body's kidney qi, promote the normal operation of body's endocrinous circulation system, delay senility, raise immunity and inhibit senile diseases. Especially, it can maintain good sexual function, raise life quality, and prolong life.

Description

Edible and medicinal fungi and Chinese herbal medicine prepare gene medicine and pharmacology product and new technique thereof

The present invention relates to change the new product and the new method field of the traditional Chinese herbal medicine of preparation with bionic enzyme engineering and fermentation engineering.

The present invention is " making process for edible mushroom produced by using sugar acid ferment method ", the application of " product of edible fungi and Chinese herbal medicine mixed fermentation brewing and method thereof " series.

The present invention has broken China's method of traditional preparation process Chinese herbal medicine product for thousands of years, also is the new exploration of Chinese medicine to mankind aging's traditional theory understanding.

China's Chinese medicine thinks that people's aging is caused by asthenia of renal qi; When the people by the youth to the prime of life to old, cause people's the physiological age and the aging of life age along with the weak of renal function, the depletion that is renal function causes the disorder of human endocrine system, blood circulation, urinary system, reproductive system and decline of spleen and stomach system or the like, cause sexual hypofunction and disappearance, people's the mental status and having bad physiques, it is white that beard and hair changes, and immunologic function weakens, thus the peculiar sufferer of the various middle-aged and elderly people that occur together.

The present invention thinks that theoretically this traditional theory of China's Chinese medicine should further develop in conjunction with the hereditism of modern science and be familiar with.We think that people's aging is subjected to the control of human body gene, the relation of DNA (deoxyribonucleic acid) and drug effect and individual inheritance's factor how, or gene information coding, and cause the length of the terminal fringes of chromosome of genetic coiled strand, as duplicating of cancerous cell, control new cellular replication, this is subjected to the restriction of telomerase again.Say in a sense, this usually is subjected to people's androgen or estrogen to restrict the gene telomerase again, it is people's senescence process, and then influence renal function, have influence on each endocrine blood circulation normal function in the human body, cause immune function of human body to reduce, old multiple distinctive some diseases, as hypertension, diabetes, tumor, cardiovascular and cerebrovascular disease or the like, and make the visual sense of people be sexual hypofunction even do not have.The people is inevitable weak in life like this, and quality of life is low, and year in longevity is not long.

On medicine and the health-product market, youth plain and recent " viagra " or the like listing is arranged abroad now, domestic with Chinese medicine or use the Chinese and western medical combination, produced the medical and health product of a lot of simple sexual function or renal function and taken stopgap measures.Facts have proved, the isolated one-sided view of this western medicine, though must bring drug effect and very big side effect is arranged, perhaps drug effect is not remarkable, finally not only can not life prolonging, the illustration that defying age, reverse side are died is many.This remove to produce the money-making of taking a short view with the operator, do not consider outside the interests of consumer, its development person does not consider the equilibrium between yin and yang of Chinese medicine and the opposition and the unification of multiple factor, be the effect of setting off by contrast and competing retroaction of depositing mutually mutually of the property of medicine between the various Chinese herbal medicine, more reckon without genetic pharmacology.

The present invention is for modern Chinese medicine and gene information is theoretical and exploration, through research for many years and practice, summed up the elite of Chinese medicine and pharmacy at all times, through coordinating repeatedly and verifying, carry out the prescription of materialist and dialectical, finished Chinese herbal medicine composition of prescription and the preparation method research of this product wine, liquid, ball.With Chinese medicine kidney qi function system is the center, and we have not only considered the Chinese medicine equilibrium between yin and yang, and more considers the nutrition of final generation and the pharmaceutical compositions combined influence to individual inheritance's factor, particularly to the influence of DNA telomerase.Institute's prescription Chinese herbal medicine can make human body can external source increase the male or estrogen of nature, and the male can make the continuous increase of gonadal hormone nature from the new sperm of endogenous continuous generation again from the reproductive function system; Can not only supply with DNA (deoxyribonucleic acid), each seed amino acid and various vitamin that human body can not produce, can constantly replenish 40 again surplus kind of mineral element and trace element; Can not only increase the ability of digesting and assimilating of gastrointestinal system, more can increase immunologic function and the therapeutical effect of human body tumor, hepatitis B, diabetes, cardiovascular and cerebrovascular disease and HIV (human immunodeficiency virus) etc.; Can not only make people's life lengthening, can keep the human body youthful vigor more muchly again, the vigor of retentivity function improves the vitality quality naturally.

The present invention realizes that through following operation accompanying drawing is seen in technological process.

First operation is with " making process for edible mushroom produced by using sugar acid ferment method " and " product of edible fungi and Chinese herbal medicine mixed fermentation brewing and method thereof " production mushroom mash, accounts for the 30% stand-by of unitary fluid amount.

Second operation, the batching Chinese herbal medicine:

A prescription: Radix Ginseng 10 Colla cornus cervis 10 Colla Corii Asini 7 Rhizoma Gastrodiaes 10 Cornu Cervi Pantotrichums 8

B prescription: Radix Codonopsis 10 Poria cocos 5 Radix Angelicae Sinensis 10 dried rhizome of rehmannia 5 cultivated lands 10 bighead atractylodes rhizomes 10 Radixs Astragali 10 tubers of multiflower knotweed 15 Eclipta prostratas 10 structure matrimony vines 7 seed of Chinese dodders 10 raspberries 7 fruit ofs Chinese magnoliavine 7 plantain seeds 10 semen astragali complanatis 10 fruit of glossy privets 8 frutus cnidiis 10 roots of bidentate achyranthes 10 bar war day 10 mulberry fruits, 7 fruits of Cherokee rose, 15 thizoma curculiginises, 10 barrenwort, 10 cynomorium songaricums, 10 Psoralea corylifolias, 10 Chinese yams, 5 roots of three-nerved spicebush, 7 rhizoma cyperis, 7 dandelions, 10 barks of eucommia, 7 dates, 8 mantis egg-cases, 10 polygala roots, 7 fructus alpiniae oxyphyllaes, 7 coix seeds, 7 banksia rose, 7 dog kidneys, 8 lycopodium calvatums, 10 cordate houttuynias, 10 BANJILIANs, 10 radix polygonati officinalis, 8 roots of large-flowered skullcap, 8 desmodiums, 10 setose thistles, 10 hawthorn, 10 Divine Comedy, 10 root tubers of aromatic turmeric, 80 reds sage root, 8 isatis roots 10

Above-mentioned prescription, its dosage is all calculated with dry weight, and unit of weight can restrain, kilogram, ton are unit of account.As being unit with the kilogram, 7 is 7 kilograms, and 10 is 10 kilograms, and 15 is 15 kilograms, then to add up to gross weight, again in water ratio in the operation, calculates the water consumption (kilogram is that unit is with the kilogram general-purpose computations) of this (criticizing), quantizes to analogize with this.By the dosage custom of China's Chinese medicine, the present invention's every part of medicine percentage calculation useless.

The 3rd operation: be 1: 10 with Radix Ginseng, Cornu Cervi Pantotrichum, Rhizoma Gastrodiae by the liquid medicine ratio at first, again by behind the 5th process flow, carrier powder is made in oven dry to decoct behind the lixiviate matter liquid (1).(2) again Colla cornus cervi, Colla Corii Asini barreling are become powder (3) after, with ground-slag mixings (4) such as Radix Ginseng, Rhizoma Gastrodiae, Cornu Cervi Pantotrichums,, make piller (5) with the allotment of A group medicine juice concentrated juice.

The 4th operation: is ten parts of waters of a medicine (dry weight) (6) with the B prescription with the ratio that wholesome water decocts medicine, and the temperature difference digestion secondary at 95-100 ℃ decocts 60 minutes (7) at every turn.When pressing elimination except that (8) behind the medicinal residues, slag and juice are placed stand-by (9) separately.

The 5th operation: medicinal residues are all pulverized (10), add 10% health water through 95-100 ℃ 60 minutes (11) of temperature sterilization, be transferred in watt cylinder of the aseptic back of sterilization, when slag temperature drop during to 32-35 ℃ (12), after reusing 0.2-0.3% edible root mould species inoculation mixing by medicinal residues, leave standstill and add a cover, at slag temperature 25-32 ℃ of bottom fermentation 48 hours (13), when the HP value reduces to 3.2, stop fermentation (14), adding sanitary water digestion under 95-100 ℃ of temperature at 1: 1 by slag weight again sterilized 60 minutes, squeeze and filter extracting juice (15) is with former decocting (boiling) medicinal liquid (A, the B prescription) mixes, 95-100 ℃ of temperature sterilization 120 minutes, be concentrated into medicine heavy with the water ratio be 1: the concentration of 3-5 (16), again with mushroom juice (simmer down to 30-50 volume) by 7: 3 mixed (17).

The 6th operation: mixed liquor is carried out hook convert seasoning (18), add 60 degree edible ethanols simultaneously, be modulated into the alcoholic acid wine product of 16-48%, commodity (20) are bottled, are packaged as to aging 90 days (19), at seasoning again, quality inspection, sterilization.

The 7th operation: as make and do not contain alcoholic acid oral liquid, finish (17) when five operations, carry out quality inspection, sterilization, seasoning, fill, be packaged as commodity (20).

Annotate: in process of production, allly mention that sterilization all is to carry out with the condensing reflux autoclave, the usage of consumer, consumption, according to concentrating degree, again through chemical examination its pharmaceutical compositions of quality inspection and nutrition content, empirical tests, finalize the design, press quality standard, determine everyone every day and each dose again.But this B set product liquor external hair washing is to promote blackening hair.

The 8th operation: whole B group drug juices are concentrated, add A group and mushroom juice (21) reconcentration (21), make pill (22) entirely.

Product of the present invention, not only be adapted to cure insufficiency of kidney-YANG, deficiency of the kidney yin, deficiency of kidney-QI, kidney blood deficiency and kidney qi blood deficiency, impotence and premature ejaculation, sexless middle-aged and elderly people patient, and after taking this " wine, liquid, ball " product for a long time, spirit and body constitution that key is to hold up the tonifying YANG of this healthy energy, strengthens the people, strengthen people's defying age and immunocompetence, can exempt the distinctive some diseases of middle-aged and elderly people, improve people's youthful vigor and quality of life, make the happy again happiness of people's longevity.

Claims

1, edible and medicinal fungi and Chinese herbal medicine prepare gene medicine and pharmacology product and new technique thereof, it is characterized in that with various edible medicinal fungis be raw material, are prepared into mushroom mash (first operation) through biological engineering; According to second operation Chinese herbal medicine compatibility is become A prescription, B prescription again, the 3rd operation is made carrier (2) again with digestions (1) such as A prescription Radix Ginseng, Rhizoma Gastrodiae, Cornu Cervi Pantotrichums, and with its slag levigation, Colla Corii Asini, Colla cornus cervi levigation (3) and (2) mixing (4) are made pill (5) with A group medicine juice; The 4th operation is that 1: 10 usefulness health decocting boils (6) by medicine (dry weight) with water, boils 60 minutes (7) at twice 95-100 ℃ temperature, slagging-off (8); Juice and slag branch are put stand-by (9); The 5th operation, medicinal residues are pulverized (10), add 60 minutes (11) of sterilization behind 10% the health water, shift, the slag temperature drop connects the edible root mould species, under the 32-25 temperature during to 32-35 ℃ (12), standing for fermentation 48 hours (13), when pH value reduces to 3.2, stop fermentation (14), heavily be to add water at 1: 1 by slag, digestion 60 minutes, extracting juice (15) mixed with preceding decoct medicinal herbs liquid, 95-100 ℃ of sterilization 120 minutes, by medication heavy with water than 1: 3-5 concentrates (16), and medicinal liquid and mushroom juice (afterwards concentrated) are pressed 7: 3 mixed (17); The 6th operation with mixed liquor blending and tasting (18), adds " product wine " that edible ethanol is deployed into the ethanol content of 16-38%, and aging is (19) more than 90 days, the quality inspection of sterilizing again packing (20); After the 5th operation is finished (17), enter (20) by the 7th operation; Enter the 8th operation after finishing (17) when the 5th operation, drug juice and mushroom juice with whole A groups, B group concentrate (21), make full pill (22).

2, claim 2 is the mushroom juice produced of this biological engineering and Chinese herbal medicine A, B prescription.

3,, use its method, Chinese herbal medicine medicated wine, liquor, the pill series of products of selecting for use its prescription to produce according to claim 1 and 2.