CN1329825A - Application of cnidiadin in agriculture - Google Patents

Application of cnidiadin in agriculture Download PDF

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Publication number
CN1329825A
CN1329825A CN 01127083 CN01127083A CN1329825A CN 1329825 A CN1329825 A CN 1329825A CN 01127083 CN01127083 CN 01127083 CN 01127083 A CN01127083 A CN 01127083A CN 1329825 A CN1329825 A CN 1329825A
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Prior art keywords
osthole
application
fruit
agricultural
common cnidium
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CN 01127083
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CN1119930C (en
Inventor
石志琦
范永坚
王裕中
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SUKE PANT PROTECTION TECHNOLOGY DEVELOPMENT CENTER JIANGSU PROV
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SUKE PANT PROTECTION TECHNOLOGY DEVELOPMENT CENTER JIANGSU PROV
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Abstract

An application of cnidiadin in agriculture, especially in insecticiding, disinfecting, and antistaling fruit, vegetable and other products is disclosed. Its advantages are broad spectrum, higher activity to colibacillus, high antistaling and antiseptic effect, and environmental protection compared with chemical pesticide.

Description

The application of Osthole on agricultural
Technical field
The present invention relates to contain the purposes of variable concentrations Osthole, especially relating to it is that the common cnidium fruit P.E of Main Ingredients and Appearance is in desinsection, sterilization, preserving fruit and vegetable utilizing and food antiseptic Application for Field.
Background technology
Its structural formula of Osthole (Osthol) is:
Figure A0112708300031
Sale is arranged, as the biological inspection of Beijing China medicine product institute on market.It is present in the extract of frutus cnidii medicinal material in a large number.Common cnidium fruit P.E mainly is made up of following composition: Osthole (Osthol), bergamot lactones (Bergapten), isopimpinellin (Isopimpinellin), imperatoria (Imperation), thymidine (Thymine), xanthotoxin (Xanthotoxin), uracil (Uracil) and xanthotoxol (Xantotoxol), citrene (Limonene) etc.
The frutus cnidii extraction process has been the technology of comparative maturity, the useful distilled water of extracting mode at present commonly used, 95% ethanol, absolute ethyl alcohol, acetone, chloroform equal solvent soak and extract, especially with absolute ethyl alcohol (available industrial alcohol replacement) comparatively economical and practical (" time precious traditional Chinese medicines medicine " 1999 the 10th volume the 6th phase P416~417).The relative amount of Osthole generally can reach 22.61% of whole extract.
There are numerous active substances to exist in the common cnidium fruit P.E, it is documented, it has certain antimutagenic effect, there is higher inhibition CPP (Cyclophosphamide cyclophosphamide) to bring out chromosome damage effect (" (canceration, distortion, sudden change " 1999 (11) (2) P71), therefore cardiovascular system, nervous centralis, genital system there is multiple pharmacological effect, in addition, antimutagenic, antitumaous effect are arranged still, " deficiency of yang " and osteoporosis that the antagonism glucocorticoid causes.Osthole by the noncompetitive calcium antagonism relax blood vessel, enteron aisle, (" Chinese herbal medicine " 1996 (27) (A09)-229-231) for sub-official rank smooth muscle.But, about common cnidium fruit P.E as botanical pesticide at the disinfectant use in agriculture insecticide, fruit and vegetable fresh-keeping agent and food preservative do not appear in the newspapers as yet.
Summary of the invention
The object of the present invention is to provide the Osthole solution that contains various concentration, comprise the plant resource common cnidium fruit P.E, it can directly develop different classes of new purposes by desired Osthole concentration without purifying on agricultural.Relate to the application of insecticidal bactericide on agricultural, relate to them, also relate to them as the application of preservative in the deep processing agricultural and animal products as the application of fruit and vegetable fresh-keeping agent on agricultural product.
The invention has the advantages that: the Osthole wide material sources, particularly containing abundant Osthole in the common cnidium fruit P.E is a kind of natural plants compound, it also there is bactericidal activity and all belongs to the wide spectrum class as the existing insecticidal activity of botanical pesticide, some agricultural insects are had tangible food refusal effect.Its effective ingredient Osthole has certain action of contace poison to brassicaceous vegetable aphid and cabbage caterpillar.To the eliminating vegetable botrytis bacterium, garlic leaf spot fungi and asparagus stem wilt bacteria all have active preferably simultaneously.Its active boundary is in 30~150g/ha.The composite proportioning control cucumber downy mildew that synergy or addition are arranged of choosing of common cnidium fruit P.E and mancozeb; Can good inhibitory effect also be arranged to black rot of pear bacterium, asparagus stem wilt bacteria, apple leaf spoting bacteria.Be expected to be applied to prevent and treat these diseases and further enlarge plant disease administer, can be applicable to the fresh-keeping of fresh fruit vegetables.Frutus cnidii have effect and the smell fragrance that suppresses the Escherichia coli breeding, and the food that is subject to e. coli contamination is had antiseptic effect.Compare with the chemical pesticide that uses in above-mentioned occasion and more to help environmental protection, help the development of pollution-free food and organic food.
The specific embodiment
Use aqueous emulsion and the common cnidium fruit P.E of pure Osthole preparation in the following example, it is molten adopting traditional industry alcohol Agent, secondary back extracts in the time of 100 ℃, its extraction rate reached 83.9%, wherein the relative amount of Osthole reaches 22%.
As the vegetable source pesticide bactericide:
Embodiment 1
Choose 2.5% extract aqueous emulsion, spraying can prevent and treat the garlic leaf spot, in leaf spot early stage spraying, after seven days second Inferior medication can effectively prevent and treat the garlic leaf spot.
Embodiment 2
With 2% common cnidium fruit P.E and the composite control cucumber downy mildew of Mancozeb; Adopt and use the same method, can to the black rot of pear bacterium, Asparagus stem wilt bacteria, Disease of Phyllsticta Mali bacterium also have preferably bacteriostasis.
Embodiment 3
30mg crude drug/ml common cnidium fruit P.E (containing approximately 0.55% Osthole) solution spray control vegetable aphid.
Embodiment 4
30~50mg crude drug/ml common cnidium fruit P.E solution (containing approximately 0.55~0.92% pure Osthole) spraying control phosphorus wing order insect Larva, experimental results show that has food refusal and action of contace poison to the low age cabbage caterpillar.
Embodiment 5
0.2 the aqueous emulsion that~2.5% pure Osthole is made spraying control asparagus stem wilt bacteria.
Embodiment 6
0.2 the aqueous emulsion that~2.5% pure Osthole is made spraying and Triazoxide as built-up control vegetables Bemisia tabaci.
As the plant source agent keeping vegetable fresh:
Embodiment 7
Asparagus, garlic stems soak in 30mg crude drug/ml frutus cnidii solution (containing approximately 0.55% pure Osthole) and dry after 20 seconds, The hypergene fungus and bacterium there is preventive effect, thereby plays preservation.
Embodiment 8
Citrus fruit is after 30~50mg crude drug/ml frutus cnidii solution (containing approximately 0.55%~0.92% pure Osthole) soaks one minute Dry, can effectively prevent and treat the dark green mildew of citrus and take place, thereby reach fresh-keeping effect.
Food preservative as plant source:
Embodiment 9
Be added in the agricultural and animal products can by 5% common cnidium fruit P.E and can reach the food antiseptic effect.
Embodiment 10
Add in the food such as dairy produce that is subject to e. coli contamination by 1% pure Osthole, kill or suppress such food pollution The flora number of bacterium, thus play the effect that prevents the relevant food corruption.

Claims (6)

1. Osthole is as the application of insecticidal bactericide on agricultural.
2. Osthole is as the application of fruit and vegetable fresh-keeping agent.
3. the application of Osthole on agricultural and animal products are anticorrosion.
4. Osthole according to claim 1 is characterized in that with the Osthole being the common cnidium fruit P.E of Main Ingredients and Appearance
As the application of botanical pesticide on agricultural.
5. Osthole according to claim 2 is characterized in that with the Osthole being the common cnidium fruit P.E of Main Ingredients and Appearance
Application as fruit and vegetable fresh-keeping agent.
6. Osthole according to claim 3 is characterized in that with the Osthole being the common cnidium fruit P.E of Main Ingredients and Appearance
Application on agricultural and animal products are anticorrosion.
CN 01127083 2001-08-08 2001-08-08 Application of cnidiadin in agriculture Expired - Fee Related CN1119930C (en)

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Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1332603C (en) * 2004-07-06 2007-08-22 江苏省农业科学院 Fructus cnidii complex composition
CN100356851C (en) * 2005-10-28 2007-12-26 江苏省农业科学院 Fructus cnidii thuricin complex insecticide
CN100409747C (en) * 2006-12-11 2008-08-13 江苏省农业科学院 Application of osthole and its re-compound in preparing pesticide for preventing and controlling rice green smut
CN100488361C (en) * 2007-04-26 2009-05-20 江苏省农业科学院 Eugenol, osthol complex biological bactericide
CN101098624B (en) * 2005-01-04 2010-12-08 Cj第一制糖株式会社 Compositions for sterilizing spores of spore-forming microorganisms comprising the extracts of torilidis fructus
WO2013044118A3 (en) * 2011-09-23 2013-07-04 Merial Limited Coumarin derivates as insect repellents
CN104351187A (en) * 2014-11-11 2015-02-18 济南新起点医药科技有限公司 Compounded fungicide with osthole and pyrimethanil as effective ingredients
CN104351188A (en) * 2014-11-11 2015-02-18 济南新起点医药科技有限公司 Microcapsule suspension for preventing and treating gray mold
CN105052959A (en) * 2015-07-31 2015-11-18 山东省烟台市农业科学研究院 Osthole and thifluzamide compounded composition and application thereof
CN105613601A (en) * 2016-02-01 2016-06-01 广西顺昌隆生物科技有限公司 Special organic germicide for Dendrobium Officinale and preparation method of special organic fungicide for Dendrobium Officinale
CN106386884A (en) * 2016-08-15 2017-02-15 蒋保珍 Traditional Chinese medicine composition for killing cabbage caterpillar
CN106472610A (en) * 2016-09-29 2017-03-08 青岛海之源智能技术有限公司 A kind of Nicotiana tabacum L. oriental tobacco budworm Pesticidal combination and preparation method thereof
CN112425610A (en) * 2021-01-22 2021-03-02 深圳市洛奇机电科技有限公司 Preparation system and application of pesticide suspending agent for preventing and treating kaffir lily leaf spot disease
CN115024359A (en) * 2022-06-21 2022-09-09 武汉安慧生物科技有限公司 Fresh-keeping composition, fresh-keeping agent, preparation method and application of fresh-keeping agent, and fresh-keeping method
CN116491513A (en) * 2023-05-06 2023-07-28 江西省农业科学院植物保护研究所 Pharmaceutical composition and application thereof in prevention and treatment of asparagus stem blight

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* Cited by examiner, † Cited by third party
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CN101803546B (en) * 2010-03-25 2011-08-10 陕西农产品加工技术研究院 Biodegradable agricultural mulching film capable of preventing and controlling root-knot nematodes and preparation method thereof
CN106818805A (en) * 2016-12-27 2017-06-13 东莞市联洲知识产权运营管理有限公司 A kind of natural acetylcholinesteraseinhibitors inhibitors and its pesticidal applications

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1332603C (en) * 2004-07-06 2007-08-22 江苏省农业科学院 Fructus cnidii complex composition
CN101098624B (en) * 2005-01-04 2010-12-08 Cj第一制糖株式会社 Compositions for sterilizing spores of spore-forming microorganisms comprising the extracts of torilidis fructus
CN100356851C (en) * 2005-10-28 2007-12-26 江苏省农业科学院 Fructus cnidii thuricin complex insecticide
CN100409747C (en) * 2006-12-11 2008-08-13 江苏省农业科学院 Application of osthole and its re-compound in preparing pesticide for preventing and controlling rice green smut
CN100488361C (en) * 2007-04-26 2009-05-20 江苏省农业科学院 Eugenol, osthol complex biological bactericide
WO2013044118A3 (en) * 2011-09-23 2013-07-04 Merial Limited Coumarin derivates as insect repellents
CN104351187B (en) * 2014-11-11 2016-08-24 青岛青知企业管理咨询有限公司 Active ingredient is the compound disinfectant of Osthole and pyrimethanil
CN104351187A (en) * 2014-11-11 2015-02-18 济南新起点医药科技有限公司 Compounded fungicide with osthole and pyrimethanil as effective ingredients
CN104351188A (en) * 2014-11-11 2015-02-18 济南新起点医药科技有限公司 Microcapsule suspension for preventing and treating gray mold
CN104351188B (en) * 2014-11-11 2016-09-07 青岛青知企业管理咨询有限公司 A kind of microcapsule suspending agent for preventing and treating gray mold
CN105052959A (en) * 2015-07-31 2015-11-18 山东省烟台市农业科学研究院 Osthole and thifluzamide compounded composition and application thereof
CN105613601A (en) * 2016-02-01 2016-06-01 广西顺昌隆生物科技有限公司 Special organic germicide for Dendrobium Officinale and preparation method of special organic fungicide for Dendrobium Officinale
CN105613601B (en) * 2016-02-01 2018-08-03 广西顺昌隆生物科技有限公司 Special organic bactericide of dendrobium candidum and preparation method thereof
CN106386884A (en) * 2016-08-15 2017-02-15 蒋保珍 Traditional Chinese medicine composition for killing cabbage caterpillar
CN106472610A (en) * 2016-09-29 2017-03-08 青岛海之源智能技术有限公司 A kind of Nicotiana tabacum L. oriental tobacco budworm Pesticidal combination and preparation method thereof
CN112425610A (en) * 2021-01-22 2021-03-02 深圳市洛奇机电科技有限公司 Preparation system and application of pesticide suspending agent for preventing and treating kaffir lily leaf spot disease
CN115024359A (en) * 2022-06-21 2022-09-09 武汉安慧生物科技有限公司 Fresh-keeping composition, fresh-keeping agent, preparation method and application of fresh-keeping agent, and fresh-keeping method
CN116491513A (en) * 2023-05-06 2023-07-28 江西省农业科学院植物保护研究所 Pharmaceutical composition and application thereof in prevention and treatment of asparagus stem blight

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