CN1329395C - 三环咪唑并吡啶 - Google Patents

三环咪唑并吡啶 Download PDF

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Publication number
CN1329395C
CN1329395C CNB028156013A CN02815601A CN1329395C CN 1329395 C CN1329395 C CN 1329395C CN B028156013 A CNB028156013 A CN B028156013A CN 02815601 A CN02815601 A CN 02815601A CN 1329395 C CN1329395 C CN 1329395C
Authority
CN
China
Prior art keywords
alkyl
alkoxyl group
hydrogen
hydroxyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB028156013A
Other languages
English (en)
Chinese (zh)
Other versions
CN1541219A (zh
Inventor
P·J·滋梅曼恩
W·－A·斯蒙
S·波斯蒂斯
W·克罗梅
W·布尔
J·森恩－比芬格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AUSTANA PHARMACEUTICAL GmbH
Original Assignee
AUSTANA PHARMACEUTICAL GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AUSTANA PHARMACEUTICAL GmbH filed Critical AUSTANA PHARMACEUTICAL GmbH
Publication of CN1541219A publication Critical patent/CN1541219A/zh
Application granted granted Critical
Publication of CN1329395C publication Critical patent/CN1329395C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C07D491/147—Ortho-condensed systems the condensed system containing one ring with oxygen as ring hetero atom and two rings with nitrogen as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
CNB028156013A 2001-08-10 2002-07-31 三环咪唑并吡啶 Expired - Fee Related CN1329395C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01119321.6 2001-08-10
EP01119321 2001-08-10

Publications (2)

Publication Number Publication Date
CN1541219A CN1541219A (zh) 2004-10-27
CN1329395C true CN1329395C (zh) 2007-08-01

Family

ID=8178292

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB028156013A Expired - Fee Related CN1329395C (zh) 2001-08-10 2002-07-31 三环咪唑并吡啶

Country Status (24)

Country Link
US (1) US7223771B2 (https=)
EP (1) EP1419163B9 (https=)
JP (1) JP2005504761A (https=)
KR (1) KR20040023739A (https=)
CN (1) CN1329395C (https=)
AT (1) ATE297931T1 (https=)
BR (1) BR0211826A (https=)
CA (1) CA2452803A1 (https=)
DE (1) DE60204701T2 (https=)
DK (1) DK1419163T5 (https=)
EA (1) EA007683B1 (https=)
ES (1) ES2243788T3 (https=)
HR (1) HRP20040229A2 (https=)
HU (1) HUP0500330A3 (https=)
IL (1) IL159554A0 (https=)
MX (1) MXPA04001277A (https=)
NO (1) NO20040604L (https=)
NZ (1) NZ531520A (https=)
PL (1) PL368195A1 (https=)
PT (1) PT1419163E (https=)
SI (1) SI1419163T1 (https=)
TW (1) TWD111798S1 (https=)
WO (1) WO2003014123A1 (https=)
ZA (1) ZA200400918B (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100393720C (zh) 2003-04-04 2008-06-11 奥坦纳医药公司 环苯并咪唑化合物
AR044129A1 (es) 2003-05-06 2005-08-24 Altana Pharma Ag Compuestos intermedios de imidazopiridina. proceso de preparacion.
JP2006528231A (ja) * 2003-05-27 2006-12-14 アルタナ　ファルマ　アクチエンゲゼルシャフト プロトンポンプ阻害剤と胃腸運動性を変更する化合物との医薬品組合せ物
EP1697358A1 (en) * 2003-12-19 2006-09-06 Altana Pharma AG Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives
AR046941A1 (es) * 2003-12-19 2006-01-04 Altana Pharma Ag Imidazopiridinas triciclicas y su uso como inhibidores de secrecion de acido gastrico
NZ549011A (en) * 2004-02-17 2009-04-30 Altana Pharma Ag Tricyclic imidazopyridines and intermediates for the synthesis thereof
US20070191334A1 (en) * 2004-03-17 2007-08-16 Altana Pharma Ag Tricyclic imidazopyridines
AU2005223397A1 (en) * 2004-03-22 2005-09-29 Altana Pharma Ag 7, 8, 9, 10- tetrahydro-imidazo [2,1-a] isoquinoline derivatives and their use as gastric acid secretion inhibitors
AR048869A1 (es) * 2004-04-26 2006-06-07 Altana Pharma Ag Bencimidazoles triciclicos
DE602005002751T2 (de) * 2004-06-09 2008-07-17 Nycomed Gmbh Substituierte tricyclische benzimidazole
AR051041A1 (es) * 2004-10-04 2006-12-13 Altana Pharma Ag Bencimidazoles triciclicos condensados
AR054772A1 (es) * 2005-06-16 2007-07-18 Altana Pharma Ag Espiro- imidazopiridinas como inhibidores de la secrecion de acido gastrico
JP2009531390A (ja) * 2006-03-31 2009-09-03 ノバルティス アクチエンゲゼルシャフト 有機化合物
WO2008071766A2 (en) * 2006-12-14 2008-06-19 Nycomed Gmbh Spiro-indene substituted imidazonaphythyridine and pyranoimidazopyridine derivatives as inhibitors of gastric acid secretion
KR200452179Y1 (ko) * 2009-05-20 2011-02-10 주식회사 신성일렉스 항공 장애물 표시 장치
EP2452680B1 (en) 2009-07-09 2019-12-18 RaQualia Pharma Inc. Acid pump antagonist for the treatment of diseases involved in abnormal gastrointestinal motility
GB201321730D0 (en) 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic agents
KR20250136992A (ko) * 2024-03-07 2025-09-17 대원제약주식회사 삼환식 유도체 및 이를 포함하는 약학적 조성물

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1251102A (zh) * 1997-03-24 2000-04-19 比克·古尔顿·劳姆贝尔格化学公司 四氢吡啶并化合物
CN1257505A (zh) * 1997-05-28 2000-06-21 比克·古尔顿·劳姆贝尔格化学公司 稠合的二氢吡喃类化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
SE9401197D0 (sv) 1994-04-11 1994-04-11 Astra Ab Active compounds
EP0971922B1 (en) * 1997-03-24 2004-04-28 ALTANA Pharma AG Tetrahydropyrido compounds
MXPA02009549A (es) * 2000-03-29 2004-05-14 Altana Pharma Ag Imidazopiridinas triciclicas.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1251102A (zh) * 1997-03-24 2000-04-19 比克·古尔顿·劳姆贝尔格化学公司 四氢吡啶并化合物
CN1257505A (zh) * 1997-05-28 2000-06-21 比克·古尔顿·劳姆贝尔格化学公司 稠合的二氢吡喃类化合物

Also Published As

Publication number Publication date
CN1541219A (zh) 2004-10-27
HUP0500330A3 (en) 2009-12-28
TWD111798S1 (zh) 2006-07-11
JP2005504761A (ja) 2005-02-17
PT1419163E (pt) 2005-10-31
DE60204701D1 (de) 2005-07-21
EP1419163B9 (en) 2005-11-09
EA007683B1 (ru) 2006-12-29
ES2243788T3 (es) 2005-12-01
KR20040023739A (ko) 2004-03-18
DK1419163T3 (da) 2005-10-17
NO20040604L (no) 2004-02-10
DK1419163T5 (da) 2005-12-19
ZA200400918B (en) 2005-04-20
HUP0500330A2 (hu) 2005-07-28
US7223771B2 (en) 2007-05-29
EP1419163B1 (en) 2005-06-15
BR0211826A (pt) 2005-06-28
PL368195A1 (en) 2005-03-21
WO2003014123A1 (en) 2003-02-20
ATE297931T1 (de) 2005-07-15
EP1419163A1 (en) 2004-05-19
MXPA04001277A (es) 2004-05-27
IL159554A0 (en) 2004-06-01
DE60204701T2 (de) 2006-08-03
SI1419163T1 (sl) 2005-12-31
HK1066213A1 (en) 2005-03-18
HRP20040229A2 (en) 2005-02-28
NZ531520A (en) 2005-10-28
CA2452803A1 (en) 2003-02-20
EA200400254A1 (ru) 2004-08-26
US20050049272A1 (en) 2005-03-03

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GR01 Patent grant
C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee