CN1325709A - Capsule for removing heat from liver and detoxicating and its preparing process - Google Patents

Capsule for removing heat from liver and detoxicating and its preparing process Download PDF

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Publication number
CN1325709A
CN1325709A CN 00117847 CN00117847A CN1325709A CN 1325709 A CN1325709 A CN 1325709A CN 00117847 CN00117847 CN 00117847 CN 00117847 A CN00117847 A CN 00117847A CN 1325709 A CN1325709 A CN 1325709A
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CN
China
Prior art keywords
radix
paeoniae rubra
radix paeoniae
rhizoma coptidis
capsule
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CN 00117847
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Chinese (zh)
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CN1170559C (en
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黄亚平
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Individual
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Individual
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Priority to CNB001178474A priority Critical patent/CN1170559C/en
Publication of CN1325709A publication Critical patent/CN1325709A/en
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Publication of CN1170559C publication Critical patent/CN1170559C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

A Chinese medicine in the form of capsule for treating hepatism is prepared from 4 Chinese-medicinal materials including coptis root, rhubarb, red peoney root, etc. Its advantages include strong physiological activity, sure curative effect and protection to liver.

Description

Removing liver heat and toxic substances capsule and preparation method thereof
The invention belongs to a kind of Chinese medicine preparation for the treatment of hepatic disease, particularly relate to a kind of removing liver heat and toxic substances capsule and preparation method thereof.
Hepatitis B is a kind of commonly encountered diseases, frequently-occurring disease, and it has become one of infectious disease of serious harm human health.At present, doctor trained in Western medicine does not still have specific medicine to the treatment hepatopathy, some so-called " hepatoprotective " actual effect is unsatisfactory, if the patient " turns to any doctor one can find when critically ill ", it is too assorted too much that medicine is used, only can increase the weight of the metabolism burden of liver, countries in the world are recognized the huge side effect that medicine brings to the mankind gradually in recent years, iatrogenic, property of medicine disease increases day by day, the chemical drugs development cost is huge, a series of problems such as medical expenses improve day by day, therefore, adopt the human green plants medicine of being yearned for, need not to experience complicated chemosynthesis process, relative low price, the Chinese patent medicine that side effect is little is the medicine that people press for.
The object of the present invention is to provide a kind of Chinese patent medicine for the treatment of acute hepatitis and diseases such as chronic hepatitis acute attack or chronic hepatitis of active stage and preparation method thereof.
Solution of the present invention is the theory according to traditional traditional Chinese medical science; summary in conjunction with old docter of TCM's clinical experience for many years; all selecting the Chinese herbal medicine with " heat-clearing and toxic substances removing; dampness removing blood stasis dispelling " function for use is that raw material is made; skim the cream off milk, have very strong physiologically active, anti-microbial effect, choleretic effect, anti-acutely inflamed effect are arranged, also there is the certain protection effect in hepatic pathology change in organization.
Removing liver heat and toxic substances capsule of the present invention is made (consumption is a weight portion) by following component:
Rhizoma Coptidis: 40-50 Radix Et Rhizoma Rhei: 15-25 Radix Paeoniae Rubra: 20-30 Spora Lygodii 5-10
The preparation capsular formula optimization weight of the present invention (part) ratio range is:
Rhizoma Coptidis: 43-47 Radix Et Rhizoma Rhei: 18-22 Radix Paeoniae Rubra: 22-27 Spora Lygodii: 6-8
The capsular optimum weight of the present invention (part) proportioning is:
Rhizoma Coptidis: 47 Radix Et Rhizoma Rhei: 21 Radix Paeoniae Rubra: 25 Spora Lygodii: 7
Rhizoma Coptidis among the present invention is a Ranunculaceae herbaceos perennial Rhizoma Coptidis Coptis chinensisFranch. rhizome.Has heat clearing and damp drying, the function of eliminating fire and detoxication, mainly contain berberine in the Rhizoma Coptidis, secondly be coptisine, 13-methyl-.psi.-coptisine., palmatine, multiple alkaloid such as palmatine, its pharmacology has broad-spectrum antibacterial action, and can suppress leptospira, ameba, influenza virus and various pathogenic fungus.The phagocytic function that makes bark of a cork tree alkali can strengthen the white blood autumn is in vivo expanded not tip blood vessel, is brought high blood pressure down, function of gallbladder promoting, analgesic, diuresis and antitumor action.
Radix Et Rhizoma Rhei among the present invention is a polygonaceae plant Rheum officinale Rheum officinale Baill. rhizome, function with purging heat to relax the bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation, mainly contain anthraquinone derivative in the Radix Et Rhizoma Rhei, contain yellow tannic acid and related substances and fatty acid, calcium oxalate, glucose, fructose and a large amount of starch again, associativity Radix Et Rhizoma Rhei acids can increase intestinal tension force and wriggling in the Radix Et Rhizoma Rhei, and can reduce the serum urea nitrogen of rat, improve the effect of renal function.
Radix Paeoniae Rubra among the present invention is the root of Ranunculaceae herbaceos perennial Paeonia lactiflora Pall., it mainly contains paeoniflorin, peonine, peonol, organic acid, tannin, cupreol, gallic acid second fat etc., have effects such as clearing away heat and cooling blood, eliminating stasis to stop pain, convulsion, blood vessel dilating, and can antibiotic and inhibition influenza virus.
Spora Lygodii among the present invention is the perennial spore of climbing up by holding on to the drying and ripening of pteridophyta Spora Lygodii Lygodium japonicum (Thunb.) Sw. of Lygodiaceae.Have inducing diuresis for treating stranguria syndrome, inducing diuresis to remove edema effect, yellow Fructus Vitis viniferae ball, bacillus pyocyaneus, shigella flexneri and Bacillus typhi etc. are all had inhibitory action.
Capsule of the present invention is a raw material with above-mentioned four flavors, and its production method that is prepared into the Chinese medicine capsule employing is:
1. get Rhizoma Coptidis, Radix Paeoniae Rubra two flavor medicinal material coarse powder mixing, add 12 times of water, decoct each one hour three times;
2. the medical filtration after Rhizoma Coptidis, Radix Paeoniae Rubra being decocted, close 1. get Rhizoma Coptidis, Radix Paeoniae Rubra two flavor medicinal material coarse powder are mixed, and add 12 times of water, decocts three times, and, concentrated, spray drying is with the airtight preservation of spray drying powder, standby then;
3. get Radix Et Rhizoma Rhei, Spora Lygodii pulverizing medicinal materials, cross 80 mesh sieves, standby;
4. get standby Radix Et Rhizoma Rhei, Spora Lygodii two flavor medicated powder and standby Rhizoma Coptidis, Radix Paeoniae Rubra spray drying powder mix homogeneously, fill zero capsule and get product.
The dosage that the present invention is used for the treatment of is adult every day three times, and each four, course of treatment of acute hepatitis A is one month; Course of treatment of acute hepatitis b is two months.
The present invention has heat-clearing and toxic substances removing, dampness removing blood stasis dispelling and rushes down the therapeutic effect that protects the liver down, and the present invention is a pure Chinese medicinal preparation, taking convenience, have no side effect, the cure rate of a course of treatment reaches 90%.
Embodiment:
Take by weighing raw material of Chinese medicine (kilogram) by following proportioning
Rhizoma Coptidis: 47 Radix Et Rhizoma Rhei: 21 Radix Paeoniae Rubra: 25 Spora Lygodii: 7
Capsule of the present invention is a raw material with above-mentioned four flavor Chinese herbal medicine, and its production method that is prepared into Chinese medicine capsule is:
1. get Rhizoma Coptidis, Radix Paeoniae Rubra two flavor medicinal material coarse powder mixing, add 12 times of water, decoct each one hour three times;
2. the medical filtration after Rhizoma Coptidis, Radix Paeoniae Rubra being decocted, close 1. get Rhizoma Coptidis, Radix Paeoniae Rubra two flavor medicinal material coarse powder are mixed, and add 12 times of water, decocts three times, and, concentrated, spray drying is with the airtight preservation of spray drying powder, standby then;
3. get Radix Et Rhizoma Rhei, Spora Lygodii pulverizing medicinal materials, cross 80 mesh sieves, standby;
4. get standby Radix Et Rhizoma Rhei, Spora Lygodii two flavor medicated powder and standby Rhizoma Coptidis, Radix Paeoniae Rubra spray drying powder mix homogeneously, fill zero capsule and get product.

Claims (4)

1. a removing liver heat and toxic substances capsule is characterized in that (consumption is a weight portion) that it is made by following component: Rhizoma Coptidis: 40-50 Radix Et Rhizoma Rhei: 15-25 Radix Paeoniae Rubra: 20-30 Spora Lygodii 5-10
2. removing liver heat and toxic substances capsule according to claim 1 is characterized in that weight (part) ratio range of each component is:
Rhizoma Coptidis: 43-47 Radix Et Rhizoma Rhei: 18-22 Radix Paeoniae Rubra: 22-27 Spora Lygodii: 6-8
3. removing liver heat and toxic substances capsule according to claim 1 is characterized in that each composition weight (part) proportioning is:
Rhizoma Coptidis: 47 Radix Et Rhizoma Rhei: 21 Radix Paeoniae Rubra: 25 Spora Lygodii: 7
4 one kinds of capsular preparation methoies of removing liver heat and toxic substances is characterized in that
(1) gets Rhizoma Coptidis, Radix Paeoniae Rubra two flavor medicinal material coarse powder mixing, add 12 times of water, decoct each one hour three times;
(2) medical filtration after Rhizoma Coptidis, Radix Paeoniae Rubra are decocted, to merge, be concentrated into extractum, spray drying, spray drying powder standby;
(3) get Radix Et Rhizoma Rhei, Spora Lygodii pulverizing medicinal materials, cross 80 mesh sieves, standby;
(4) get standby Radix Et Rhizoma Rhei, Spora Lygodii two flavor medicated powder and standby Rhizoma Coptidis, Radix Paeoniae Rubra spray drying powder mix homogeneously, fill zero capsule and get product.
CNB001178474A 2000-05-25 2000-05-25 Capsule for removing heat from liver and detoxicating and its preparing process Expired - Fee Related CN1170559C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNB001178474A CN1170559C (en) 2000-05-25 2000-05-25 Capsule for removing heat from liver and detoxicating and its preparing process

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB001178474A CN1170559C (en) 2000-05-25 2000-05-25 Capsule for removing heat from liver and detoxicating and its preparing process

Publications (2)

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CN1325709A true CN1325709A (en) 2001-12-12
CN1170559C CN1170559C (en) 2004-10-13

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101618085B (en) * 2008-07-01 2011-09-28 北京亚东生物制药有限公司 Traditional Chinese medicine composition for treating liver and gallbladder dampness-heat disease and preparation method thereof
CN101683404B (en) * 2008-09-22 2012-06-13 北京亚东生物制药有限公司 Traditional Chinese medicine composition for treating dampness and heat in liver and gallbladder and preparation method thereof
CN102552518A (en) * 2011-12-31 2012-07-11 沈阳药科大学 Application of four traditional Chinese medicines in relieving liver and kidney toxicity

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101618085B (en) * 2008-07-01 2011-09-28 北京亚东生物制药有限公司 Traditional Chinese medicine composition for treating liver and gallbladder dampness-heat disease and preparation method thereof
CN101683404B (en) * 2008-09-22 2012-06-13 北京亚东生物制药有限公司 Traditional Chinese medicine composition for treating dampness and heat in liver and gallbladder and preparation method thereof
CN102552518A (en) * 2011-12-31 2012-07-11 沈阳药科大学 Application of four traditional Chinese medicines in relieving liver and kidney toxicity

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CN1170559C (en) 2004-10-13

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