CN1325099C - Mine-tranquilizing soporific capsule - Google Patents
Mine-tranquilizing soporific capsule Download PDFInfo
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Abstract
The present invention relates to a mind-tranquilizing soporific capsule which belongs to the field of traditional Chinese medicines. The present invention is prepared from a plurality of pure traditional Chinese medicine herbs of selected fresh deer's heart, fresh deer's blood, tuckahoe, spine date seed, dried longan pulp, schisandra, common anemarrhena rhizome, condensed buffalo horn powder, ophiopogon root and radix glycyrrhiza according to traditional Chinese medicine preparation technology. The mind-tranquilizing soporific capsule as a pure traditional Chinese medicine preparation has the advantages of no toxic or side effect and conspicuous curative effect, and has the functions of nourishing yin, clearing heat, nourishing the heart and tranquilizing the mind after the traditional Chinese medicine herbs are combined. The present invention has obvious effect on treating vexation, insomnia, hypersomnia with dreams, dizziness, tinnitus, dry mouth and throat, vexing heat in the heart, palms and foot arches, palpitation, sweating, amnesia, limp aching lumbus and knees, etc. caused by fire excess from yin deficiency belonging to neurasthenia and neurosis.
Description
Technical field
The present invention relates to the field of Chinese medicines, particularly a kind of Chinese medicinal capsule of Cure for insomnia disease.
Background technology
As everyone knows, current society has entered the epoch of scientific and technological progress and rapid economic development, especially after the economy of entering into the market, the various contradictions of the variation of keen competition and situation, society and economic field constantly occur, everyone is positive the studying the countermeasure of building of the four modernizations, factors such as thinking hard, try every possible means and work rhythm is accelerated, life is irregular makes people's " psychentonia ", the chance showed increased of " work with one's mind and overtax one's nerves ".Therefore, make the people often feel " feeling exhausted ", if things go on like this, easily suffer from " neurasthenia ", diseases such as insomnia, forgetful, vexed dreaminess, dizziness, tinnitus usually occur, influence work, study and daily life.The traditional Chinese medical science thinks that it is a lot of to form this sick reason, as ponders over factors such as overstrain, interior sad spleen, YANG failing to relate with YIN, disarmony between the heart and kidney, hyperactivity of fire caused by deficiency of YIN, liver-yang disturbance, the heart and gallbladder deficiency of vital energy and disorder of the stomach and all can influence the mind and cause being insomnia.Aspect treatment, the doctor has carried out clinical research to the disease of being insomnia in recent years, mainly is acupoint therapy and pharmacotherapy.Acupoint therapy mainly comprises magnetics therapy and ear acupuncture pressing therapy and acupuncture therapy.Pharmacotherapy is mainly in the majority with the treatment by Chinese herbs disease of being insomnia, but said method exist the course of treatment long, take effect slowly, the medicine cost is than problems such as height.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicinal capsule of Cure for insomnia disease, problems such as the treatment course of treatment that has solved that existing Cure for insomnia disease drug exists is long, it is slow to take effect, medicine cost height.
According to the theory of Chinese medical science and the clinical trial certificate of motherland, treatment cardiopalmus, insomnia, the deficient lumbago of neurasthenia should be intended to reinforcing the heart, repose, tonify deficiency and blood, benefit are smart.Therefore, the pure Chinese herbal medicine of the selected following all flavors of the present invention is made by traditional Chinese medicine preparation technology.Its concrete prescription following (by ratio of weight and the number of copies):
50～200 parts of 40～86.7 parts of bright deer of bright Cor Cervi
50～200 parts of 50～200 parts of Semen Ziziphi Spinosaes of Poria
36.7～96.7 parts of 30～102 parts of Fructus Schisandrae Chinensis of Arillus Longan
6.8～36.8 parts of 30～80 parts of Pulvis Cornus Bubali Concentratuss of the Rhizoma Anemarrhenae
Radix Ophiopogonis, 46.70～86.7 portions of Radix Glycyrrhizaes were 14.1～54.1 parts
Optimum ratio of the present invention is (by ratio of weight and the number of copies):
100 parts of 66.7 parts of bright Sanguis cervi of bright Cor Cervi
100 parts of 100 parts of Semen Ziziphi Spinosaes of Poria
66.7 parts of 82 parts of Fructus Schisandrae Chinensis of Arillus Longan
16.8 parts of 50 parts of Pulvis Cornus Bubali Concentratuss of the Rhizoma Anemarrhenae
Radix Ophiopogonis, 66.7 portions of Radix Glycyrrhizaes were 34.1 parts
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral formulations.Preferable preparation technique of the present invention is as follows:
More than ten flavor medicines, 1/3rd amounts of getting Fructus Schisandrae Chinensis, Semen Ziziphi Spinosae, Poria are dry, are ground into fine powder; Residue 2/3rds amount Poria and Radix Ophiopogonis, Arillus Longan, the Rhizoma Anemarrhenae, Radix Glycyrrhizae decoct with water three times, add for the first time 10 times of amounts of water, decocted 3 hours, and added 8 times of amounts of water for the second time, decocted 2 hours, add 8 times of amounts of water for the third time, decocted 1 hour, and filtered merging filtrate, left standstill 24 hours, and got supernatant concentration and be 1.10～1.40 thick paste to temperature relative density 40 ℃～80 ℃ the time; With fine powder mixings such as above-mentioned thick paste and Fructus Schisandrae Chinensis, drying is ground into fine powder; Cor Cervi, Sanguis cervi, Pulvis Cornus Bubali Concentratus are dry respectively and be ground into fine powder; With above-mentioned fine powder mixing, incapsulate, promptly.
[character] this product is a capsule, and content is brown to tan powder; Mildly bitter flavor and acid.
[specification] every dress 0.3g.
[function cures mainly] nourishing YIN and clearing away heat, tranquilizing by nourishing the heart.Be used for the neurasthenia, neurosis belongs to dysphoria and insomnia or the dreaming often and waking easily that hyperactivity of fire caused by deficiency of YIN causes, dizziness and tinnitus, dry mouth and throat, dysphoria with feverish sensation in the chest palms and soles, the cardiopalmus sweating, forgetful, diseases such as soreness of the waist and knees.
[usage and dosage] is oral.One time 4,3 times on the one, child dose cuts down according to the circumstance, or follows the doctor's advice.
Among the present invention:
Bright Cor Cervi is salty, sweet, warm.The GUIXIN warp.Reinforcing the heart, repose.Be used for cardiopalmus, insomnia, neurasthenia, be monarch drug in the side.
Bright Sanguis cervi is salty, sweet, warm.GUIXIN, kidney channel.Tonify deficiency and blood, benefit essence.Be used for deficient lumbago, cardiopalmus, insomnia, consumptive lung disease is spitted blood, bleeding not during menses, sexual impotence, pox poison or poison of drug are monarch drug in the side.
Poria is gentle, and diuretic and not feeling frustrated is the key medicine of promoting diuresis to eliminate damp pathogen.All dysuria, the edema distension, no matter the card that stops in the phlegm retention belongs to the cold heat that belongs to, and it is true to belong to void, all can use.Insufficiency of the spleen all cards are controlled in the spleen invigorating of Poria energy.Poria is calmed the nerves, and is used for malaise, and palpitation and insomnia is ministerial drug in the side.
Semen Ziziphi Spinosae is sweet flat, and the liver benefiting arresting sweating that can nourish heart is the product that nourishing is calmed the nerves, and is the key medicine of controlling blood deficiency, irritated sleeplessness, is ministerial drug in the side.
The sweet temperature of Arillus Longan is gone into heart spleen two warps, and reinforcing the heart spleen replenishing QI and blood is controlled deficiency of both the heart and spleen, and the two diseases thanks to of QI and blood are ministerial drug in the side.
Fructus Schisandrae Chinensis sour in the mouth convergence, gentle YIN nourishing are gone into lung kidney two warps, can on the gas of astringing the lung, following nourishing kidney-yin.Nourish heart the moon and mind tranquilizing and the heart calming is adjuvant drug in the side.
Rhizoma Anemarrhenae bitter cold can clearing away heat-fire, and is nourshing Yin and drynsessmoistening prescription and borrow its heat clearing away and nourishing yin effect to quench the thirst with relieving restlessness.Rhizoma Anemarrhenae bitter cold consolidating YIN, sweet can nourishing YIN, its nourishing YIN to lower pathogenic fire commonly used is done in order to control the osteopyrexia and fever due to hyperactivity of fire caused by deficiency of YIN, the hepatic and renal YIN deficiency, diseases such as vexed night sweat are adjuvant drug in the side.
Pulvis Cornus Bubali Concentratus, salty in the mouth is cold in nature, heat clearing away, removing heat from blood, detoxify, be used for calentura dress heat, unconsciousness and delirium, hemorrhage, the macule of heat in blood, effectiveness is close with Cornu rhinocerotis, is adjuvant drug in the side.
Cold, the nourishing lung-YIN of sweet and slightly bitter taste Radix Ophiopogonis, reinforcing stomach reg fluid, relieving restlessness clears away heart-fire.Control warm-dryness syndrome impairing the lung, deficiency of YIN chronic cough.Diseases such as deficiency of YIN-blood, interior-heat impairment of body fluid are adjuvant drug in the side.
The Radix Glycyrrhizae sweet in the mouth is gone into taste, controls deficiency of spleen-QI and stomach-QI, goes into heart channel and QI invigorating, controls not whole, the severe palpitation of arteries and veins rule of deficiency of heart-blood.Coordinating the actions of various ingredients in a prescription is messenger drug in the side to separate hundred poison.
Good effect of the present invention is: medicine is a pure Chinese medicinal preparation, has no side effect, and is evident in efficacy, nourishing YIN and clearing away heat, tranquilizing by nourishing the heart.Neurasthenia, function of nervous system's disease are belonged to dysphoria and insomnia or the dreaming often and waking easily that hyperactivity of fire caused by deficiency of YIN causes, dizziness and tinnitus, dry mouth and throat, dysphoria with feverish sensation in the chest palms and soles, the cardiopalmus sweating, forgetful, diseases such as soreness of the waist and knees are evident in efficacy.
For verifying therapeutic effect of the present invention, the patient who 102 routine Chinese medical discriminations is syndrome of hyperactivity of fire due to deficiency of YIN takes mine-tranquilizing soporific glue regulation treatment, has obtained promising result, now is summarized as follows:
One, clinical data
Case is selected: observe among the 102 routine patients male 45 examples, women 57 examples; Age: 18～30 years old 7 example, 31～40 years old 26 example, 41～50 years old 33 example, 51～65 years old 36 example, 45.2 ± 10.28 years old mean age; The course of disease: be less than 1 year person's 11 example, 1～3 year person's 41 example, 4～5 years person's 21 examples, person's 29 examples more than 6 years, average course of disease is 3.65 ± 2.37 years; Occupation: cadre's 42 examples, workman's 38 examples, teacher's 2 examples, peasant's 8 examples, other 12 examples; Insomnia degree: slight 48 examples, moderate 47 examples, severe 7 examples.Chinese medical discrimination: 102 examples are syndrome of hyperactivity of fire due to deficiency of YIN.
Two, study subject
The Chinese medical discrimination standard: dysphoria and insomnia or dreaming often and waking easily, dizziness and tinnitus, dry mouth and throat, dysphoria with feverish sensation in the chest palms and soles, the cardiopalmus sweating, forgetful, or soreness of the waist and knees is arranged, seminal emission, menoxenia, red tongue, thready and rapid pulse.
Include the case standard in: have the insomnia classical symptom, continue to meet the Chinese medical discrimination standard, can include the test case in more than 1 month.
Get rid of the case standard, comprise inadaptation or rejecting standard:
Every systemic disease such as pain, heating, cough, operation etc., and external environmental interference factor causer;
Age, gestation or women breast-feeding their children were to this medicine allergy sufferers below 18 one full year of life or the over-65s person;
Be associated with serious constitutional disorder such as cardiovascular, lung, liver, kidney and hemopoietic system, the psychotic;
All standards of including in that do not meet, not medication in accordance with regulations can't be judged that curative effect or data are not congruent to affect the treatment and safety judgement person.
Three, observational technique
1, observe medication: " mine-tranquilizing soporific capsule " provided by Jilin Changbaishan Pharmaceutical Group Co., Ltd..
2, the medication and the course of treatment: oral, each 4,3 times on the one, serveing on for 4 weeks is a course of treatment, viewing duration stop using hypnosis, calmness and similar medicine.
3, observation index: fill in symptom, sign and relevant physico-chemical examination result before the medication on request, comprise routine blood test, routine urinalysis, liver function, renal function, electrocardiogram, finish to carry out comprehensive review the course of treatment.
4, statistical method: adopt self medication cross-reference method, continuous data is carried out the t check; Enumeration data is carried out sum of ranks or X
2Check.
Four, observed result
1, efficacy determination: the unified standard of pressing mine-tranquilizing soporific capsule clinical research plan regulation is judged.
Clinical symptoms press the light and heavy degree difference with +++, ++ ,+,-expression.
Produce effects: sleep is clearly better, and increases the length of one's sleep more than 3 hours, and Depth of sleep increases.
Effectively: sx, the length of one's sleep is than increasing in the past, but increases less than 3 hours.
Invalid: insomnia nothing in treatment back is obviously improved or is increased the weight of.
2, insomnia weight split pole standard
Slightly: sleep is waken up often or is slept and unstable, and wake up too early but do not influence work morning.
Moderate: do not have enough sleep 4 hours, but still can adhere to work.
Severe: lie awake all night, be difficult to adhere to operate as normal.
3, efficacy analysis
Table 1 mine-tranquilizing soporific capsule is to the comprehensive therapeutic effect of insomnia
| The example number | Produce effects example number (%) | Effective routine number (%) | Invalid routine number (%) | Total effective rate (%) |
| 102 | 56(54％) | 41(40.19％) | 5(4.9％) | 95.1 |
Table 2 mine-tranquilizing soporific capsule is to the influence of insomnia
| Symptom | n | Before the treatment | After the treatment | The U value | The P value | ||||||
| +++ | ++ | + | - | +++ | ++ | + | - | ||||
| The forgetful soreness and weakness of waist and knees seminal emission of the dysphoria in chestpalms-soles palpitaition sweating of dysphoria and insomnia or dreaming often and waking easily dizziness and tinnitus dry mouth and throat irregular menstruation | 102 102 102 102 102 102 102 25 44 | 45 13 2 1 8 2 3 0 1 | 30 45 54 46 49 43 34 1 8 | 27 40 43 43 33 30 49 11 13 | 0 4 3 12 12 27 16 13 22 | 4 1 0 0 0 0 0 0 0 | 11 5 1 1 2 10 4 0 1 | 48 42 27 33 26 33 28 4 8 | 39 54 74 68 74 59 70 21 35 | 9.32 9.16 10.9 9.15 11.4 5.65 8.1 1.9 1.4 | ＜0.01 ＜0.01 ＜0.01 ＜0.01 ＜0.01 ＜0.01 ＜0.01 ＞0.05 ＞0.05 |
Through the rank test statistical analysis, before and after the treatment influence of seminal emission, menoxenia there is not obvious pass different (P＞0.05), to dysphoria and insomnia, dreaming often and waking easily, there is significant difference (P＜0.01) in the influence of symptoms such as dizziness and tinnitus, dry mouth and throat, dysphoria with feverish sensation in the chest palms and soles, cardiopalmus sweating, forgetful, soreness of the waist and knees, in conjunction with clinical statement, mine-tranquilizing soporific capsule is to the above-mentioned symptom effect of having clear improvement.
Table 3 mine-tranquilizing soporific capsule is to the influence of picture of the tongue, pulse condition
| Picture of the tongue | Pulse condition | |||
| Normally | Unusually | Normally | Unusually | |
| After treating before the treatment | 8 6.8 | 94 34 | 7 54 | 95 48 |
| P(X 2) | ＜0.001(75.1) | ＜0.001(51.6) | ||
Through X
2Inspection statistics is analyzed, and all there is significant difference (P＜0.001) in the influence to picture of the tongue, pulse condition before and after the treatment, and picture of the tongue, pulse condition the have clear improvement effect of mine-tranquilizing soporific capsule to the syndrome of hyperactivity of fire due to deficiency of YIN patient is described.
Table 4 mine-tranquilizing soporific capsule is to the influence of the length of one's sleep
| The example number | Before the treatment | After the treatment | The t value | The P value |
| 102 | 3.78±1.05 | 6.04±0.97 | 11.54 | ＜0.01 |
Analyze through the t inspection statistics, mine-tranquilizing soporific capsule can obviously improve sleep, prolongs the length of one's sleep (P＜0.01).
Table 5 mine-tranquilizing soporific capsule is to the influence of routine blood test
| n＝102 | RBC(×10 12/L) | Hb(g/L) | WBC(×10 9/L) |
| After treating before the treatment | 4.41±0.52 4.57±0.61△ | 127.2±11.3 127.9±10.6△ | 7.31±1.39 1.02±0.98△ |
Annotate: compare P all＞0.05 before △ represents to treat the back and treats.
Last table result shows that mine-tranquilizing soporific capsule has no adverse effects to routine blood test.
Five, safety detects
102 routine patients all carry out blood, routine urinalysis, liver function and renal function, Electrocardioscopy after smelting is treated, do not find untoward reaction before and after the treatment, other toxic and side effects do not occur, prove this product safety non-toxic.
Six, conclusion
By 102 routine patients are taken " mine-tranquilizing soporific capsule " treatment after observation, the result shows that its obvious effective rate is 54.9%, total effective rate reaches 95.1%.This medicine improves significantly to symptom, the sign of insomnia, and can obviously prolong the length of one's sleep, alleviates the insomnia degree, improves sleep quality.Clinical observation routine blood test, routine urinalysis, hepatic and renal function and electrocardiogram have no adverse effects before and after treatment, do not find any toxic and side effects.
The specific embodiment:
The following example is intended to further describe for example the present invention, rather than limits the present invention by any way.Under the prerequisite that does not deviate from the spirit and principles in the present invention, any change or change that those of ordinary skills that the present invention did are realized easily all will fall in the claim scope of the present invention.
Embodiment 1:
Take by weighing each medicine by following weight ratio, bright Cor Cervi 40g, bright Sanguis cervi 50g, Poria 50g, Semen Ziziphi Spinosae 50g, Arillus Longan 30g, Fructus Schisandrae Chinensis 36.7g, Rhizoma Anemarrhenae 30g, Pulvis Cornus Bubali Concentratus 6.8g, Radix Ophiopogonis, 46.70g, Radix Glycyrrhizae 14.1g were standby;
More than ten flavor medicines, 1/3rd amounts of getting Fructus Schisandrae Chinensis, Semen Ziziphi Spinosae, Poria are dry, are ground into fine powder; Residue 2/3rds amount Poria and Radix Ophiopogonis, Arillus Longan, the Rhizoma Anemarrhenae, Radix Glycyrrhizae decoct with water three times, add for the first time 10 times of amounts of water, decocted 3 hours, and added 8 times of amounts of water for the second time, decocted 2 hours, add 8 times of amounts of water for the third time, decocted 1 hour, and filtered merging filtrate, left standstill 24 hours, and got supernatant concentration and be 1.40 thick paste to temperature relative density 40 ℃ the time; With fine powder mixings such as above-mentioned thick paste and Fructus Schisandrae Chinensis, drying is ground into fine powder; Cor Cervi, Sanguis cervi, Pulvis Cornus Bubali Concentratus are dry respectively and be ground into fine powder; With above-mentioned fine powder mixing, incapsulate, promptly.
Embodiment 2:
Take by weighing each medicine by following weight ratio, bright Cor Cervi 66.7g, bright Sanguis cervi 100g, Poria 100g, Semen Ziziphi Spinosae 10g, Arillus Longan 82g, Fructus Schisandrae Chinensis 66.7g, Rhizoma Anemarrhenae 50g, Pulvis Cornus Bubali Concentratus 16.8g, Radix Ophiopogonis, 66.7g, Radix Glycyrrhizae 34.1g were standby;
More than ten flavor medicines, 1/3rd amounts of getting Fructus Schisandrae Chinensis, Semen Ziziphi Spinosae, Poria are dry, are ground into fine powder; Residue 2/3rds amount Poria and Radix Ophiopogonis, Arillus Longan, the Rhizoma Anemarrhenae, Radix Glycyrrhizae decoct with water three times, add for the first time 10 times of amounts of water, decocted 3 hours, and added 8 times of amounts of water for the second time, decocted 2 hours, add 8 times of amounts of water for the third time, decocted 1 hour, and filtered merging filtrate, left standstill 24 hours, and got supernatant concentration and be 1.25 thick paste to temperature relative density 60 ℃ the time; With fine powder mixings such as above-mentioned thick paste and Fructus Schisandrae Chinensis, drying is ground into fine powder; Cor Cervi, Sanguis cervi, Pulvis Cornus Bubali Concentratus are dry respectively and be ground into fine powder; With above-mentioned fine powder mixing, incapsulate, promptly.
Embodiment 3:
Take by weighing each medicine by following weight ratio, bright Cor Cervi 86.7g, bright Sanguis cervi 200g, Poria 200g, Semen Ziziphi Spinosae 200g, Arillus Longan 102g, Fructus Schisandrae Chinensis 96.7g, Rhizoma Anemarrhenae 80g, Pulvis Cornus Bubali Concentratus 36.8g, Radix Ophiopogonis, 86.7g, Radix Glycyrrhizae 54.1g were standby;
More than ten flavor medicines, 1/3rd amounts of getting Fructus Schisandrae Chinensis, Semen Ziziphi Spinosae, Poria are dry, are ground into fine powder; Residue 2/3rds amount Poria and Radix Ophiopogonis, Arillus Longan, the Rhizoma Anemarrhenae, Radix Glycyrrhizae decoct with water three times, add for the first time 10 times of amounts of water, decocted 3 hours, and added 8 times of amounts of water for the second time, decocted 2 hours, add 8 times of amounts of water for the third time, decocted 1 hour, and filtered merging filtrate, left standstill 24 hours, and got supernatant concentration and be 1.10 thick paste to temperature relative density 80 ℃ the time; With fine powder mixings such as above-mentioned thick paste and Fructus Schisandrae Chinensis, drying is ground into fine powder; Cor Cervi, Sanguis cervi, Pulvis Cornus Bubali Concentratus are dry respectively and be ground into fine powder; With above-mentioned fine powder mixing, incapsulate, promptly.
Claims (3)
1, a kind of Chinese medicinal capsule of Cure for insomnia disease is characterized in that: make that its active component raw material medicine is made up of the component of following weight proportioning:
50～200 parts of 40～86.7 parts of bright Sanguis cervi of bright Cor Cervi
50～200 parts of 50～200 parts of Semen Ziziphi Spinosaes of Poria
36.7～96.7 parts of 30～102 parts of Fructus Schisandrae Chinensis of Arillus Longan
6.8～36.8 parts of 30～80 parts of Pulvis Cornus Bubali Concentratuss of the Rhizoma Anemarrhenae
Radix Ophiopogonis, 46.70～86.7 portions of Radix Glycyrrhizaes were 14.1～54.1 parts.
2, the Chinese medicinal capsule of a kind of Cure for insomnia disease according to claim 1 is characterized in that: make that its active component raw material medicine is made up of the component of following weight proportioning:
100 parts of 66.7 parts of bright Sanguis cervi of bright Cor Cervi
100 parts of 100 parts of Semen Ziziphi Spinosaes of Poria
66.7 parts of 82 parts of Fructus Schisandrae Chinensis of Arillus Longan
16.8 parts of 50 parts of Pulvis Cornus Bubali Concentratuss of the Rhizoma Anemarrhenae
Radix Ophiopogonis, 66.7 portions of Radix Glycyrrhizaes were 34.1 parts.
3, the Chinese medicinal capsule of Cure for insomnia disease according to claim 1 and 2 is characterised in that: it is made according to following method:
More than ten flavor medicines, 1/3rd amounts of getting Fructus Schisandrae Chinensis, Semen Ziziphi Spinosae, Poria are dry, are ground into fine powder; Residue 2/3rds amount Poria and Radix Ophiopogonis, Arillus Longan, the Rhizoma Anemarrhenae, Radix Glycyrrhizae decoct with water three times, add for the first time 10 times of amounts of water, decocted 3 hours, and added 8 times of amounts of water for the second time, decocted 2 hours, add 8 times of amounts of water for the third time, decocted 1 hour, and filtered merging filtrate, left standstill 24 hours, and got supernatant concentration and be 1.10～1.40 thick paste to temperature relative density 40 ℃～80 ℃ the time; With fine powder mixings such as above-mentioned thick paste and Fructus Schisandrae Chinensis, drying is ground into fine powder; Cor Cervi, Sanguis cervi, Pulvis Cornus Bubali Concentratus are dry respectively and be ground into fine powder; With above-mentioned fine powder mixing, incapsulate, promptly.
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| CN1325099C true CN1325099C (en) | 2007-07-11 |
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| CN102614346B (en) * | 2012-04-01 | 2013-12-04 | 吉林济邦洪德堂制药有限公司 | Deer blood nerve soothing granules and preparation method thereof |
| CN102698049B (en) * | 2012-06-15 | 2013-10-09 | 李良 | Crude rehmannia root Chinese medicinal decoction for treating palpitation and preparation method thereof |
| CN103734711A (en) * | 2013-11-24 | 2014-04-23 | 郭国康 | Composition for promoting heart health |
| CN112946094B (en) * | 2020-11-27 | 2023-03-31 | 吉林修正药业新药开发有限公司 | Heart-nourishing and sleep-improving capsule HPLC characteristic spectrum construction method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1080535A (en) * | 1992-06-29 | 1994-01-12 | 赵奕成 | Intelligent brain health care bag |
| CN1175445A (en) * | 1997-07-10 | 1998-03-11 | 迟经惠 | Brain refreshing pill for dizziness |
-
2005
- 2005-06-14 CN CNB2005100168681A patent/CN1325099C/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1080535A (en) * | 1992-06-29 | 1994-01-12 | 赵奕成 | Intelligent brain health care bag |
| CN1175445A (en) * | 1997-07-10 | 1998-03-11 | 迟经惠 | Brain refreshing pill for dizziness |
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| CN1709476A (en) | 2005-12-21 |
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