CN1323635A - Antibacterial medical dressing of composite nanometer material - Google Patents

Antibacterial medical dressing of composite nanometer material Download PDF

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Publication number
CN1323635A
CN1323635A CN 01113643 CN01113643A CN1323635A CN 1323635 A CN1323635 A CN 1323635A CN 01113643 CN01113643 CN 01113643 CN 01113643 A CN01113643 A CN 01113643A CN 1323635 A CN1323635 A CN 1323635A
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China
Prior art keywords
layer
nano
medical dressing
gauze
antibacterial medical
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CN 01113643
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Chinese (zh)
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CN1165347C (en
Inventor
顾宁
张宇
虞伟
张海黔
徐丽娜
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Southeast University
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Southeast University
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Priority to CNB01113643XA priority Critical patent/CN1165347C/en
Publication of CN1323635A publication Critical patent/CN1323635A/en
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Publication of CN1165347C publication Critical patent/CN1165347C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

The present invention relates to antibacterial medical dressing made of nanometer material which possesses hydrophilic and hydrophoblic functions and high antibacterial property, said dressing is composed of three functional layers and one supporting layer, the first layer is antibacterial layer which is a composite layer of nanometer antibacterial material on gauze layer; the second layer is hydrophilic layer which is treated by UV light; the third layer is hydrophobic layer which is a polymer thin layer possessing porous structure capable of water vapor permeation, a nanometer material layer is covered on this thin layer, the outermost is supporting layer.

Description

The antibacterial medical dressing of composite nano materials
The present invention is a kind of medical dressing that hydrophilic and hydrophobic function has high anti-microbial property simultaneously that has, and belongs to the technical field that medical material is made.
Nano material is the focus of present material science research because of quantum size effect, skin effect and dielectric confinement effect etc. have outstanding functional characteristic.Wherein, how to realize its again the application of biomedical sector be one significant and press for the problem of research.
At the development field of advanced medical dressing, nano material has demonstrated the outstanding integrated quality that is better than traditional material.As develop wide spectrum, efficient, safe nano-antibacterial silver granule is used for medical dressing and treats burn and scald, wound, infection suppurates etc.But the particulate cost of preparation fine silver is very high, has restricted it and has used widely.On the other hand, medical dressing is faced with such problem often in application, and promptly how the too much moisture of wound location is removed, and the infiltration that how to prevent outside moisture, guarantees the breathability of dressing simultaneously again.Utilize the characteristic of nano material and come ingenious addressing these problems, still be not reported in conjunction with macromolecule that can penetrating aqueous vapor.Existing solution fiber hydrophilic and hydrophobic method are normal to adopt organic surfactant molecule, but inevitable its safety in utilization problem, especially in medical field.To the unidirectional penetrating problem of aqueous vapor, useful unidirectional group stream organic polymer solves, but needs the used high molecular structure of strict control, and this brings very big difficulty to production technology.Along with the nano material preparation technology and be used for the progressively development of process for modifying surface, the wait in expectation advantageous characteristic that can utilize nano material and solve the problems referred to above by certain treatment technology of medical dressing application is to obtain the medical dressing that integrated quality is better and have complex function.
Purpose of the present invention just provides a kind of better antibacterial action that has, and internal layer possess hydrophilic property, skin have the antibacterial medical dressing of hydrophobic composite nano materials.
The antibacterial medical dressing of composite nano materials of the present invention adopts the form of multiple structure to combine, this dressing is made up of three one functional layer and one deck supporting layer, ground floor is an antibiotic layer, and this layer is to be undertaken compound by self-assembling method and nano anti-biotic material on the gauze layer; The second layer is a hydrophilic layer, and this layer is by the method for hot dipping stain in conjunction with ultraviolet lighting, with the super hydrophilic treated of nano material work that is compounded on the gauze with gauze; The 3rd layer is hydrophobic layer, and this layer is the macromolecule thin layer with loose structure that can penetrating aqueous vapor, in the compound one deck nano material of this thin layer upper surface, does super-hydrophobic processing then, and outermost is a supporting layer.Nano anti-biotic material is for containing Ag +SiO 2The ZnO nanoparticle of nanoparticle or coated with silver on surface nano thin-layer.Being compounded in and making super material hydrophilic or super-hydrophobic processing on the gauze is TiO 2Or SiO 2Nano powder.Macromolecule thin layer with loose structure that can penetrating aqueous vapor is a polyurethane.The central authorities of supporting layer have the window of being convenient to ventilate.
The invention has the advantages that:
1. nano anti-biotic material is used for medical dressing and has the incomparable integrated quality of conventional medical antibacterial: wide spectrum, long-acting, safe, superpower sterilization, pollution-free, convenient, can promote wound healing, can not diseaseful drug resistance;
2. can effectively absorb the wound location excessive moisture, prevent that outside moisture from soaking into, but it be outwards penetrating not influence aqueous vapor;
3. the used TiO of super-hydrophobic processing 2Nanoparticle has sterilizing function under daily illumination, thereby can prevent the intrusion of outside antibacterial.
4. use the composite nano materials of preparation, as contain Ag +SiO 2The ZnO nanoparticles of nanoparticle, coated with silver on surface nano thin-layer etc. replace the fine silver nanoparticle, reduce cost under the condition that does not reduce performance.
5. use TiO 2Or SiO 2Nano-powder carries out super hydrophilic and super-hydrophobic processing to medical dressing and absorbs the wound location excess moisture and prevent the wetted problem of outside moisture to solve.
Fig. 1 is a structural representation cutaway view of the present invention.
Embodiment of the present invention are as follows:
Preparation earlier contains Ag +SiO 2The ZnO nanoparticle of nanoparticle or coated with silver on surface nano thin-layer.
Its funtion part is divided into three layers:
Ground floor:, (as contain Ag by self-assembling technique and nano anti-biotic material with the gauze layer of contact skin +SiO 2The ZnO nanoparticle of nanoparticle, coated with silver on surface nano thin-layer) carries out compoundly, can bring into play wide spectrum, efficient, safe sterilization, bacteria resistance function, and can promote wound healing, and can not produce resistance;
The second layer: use TiO 2Or SiO 2Nano-powder surpasses the gauze layer of hydrophilic treated (hot dipping stain technology is in conjunction with ultraviolet lighting), and strong absorptive is arranged, and does not have too much moisture to guarantee wound location;
The 3rd layer: have macromolecule (polyurethane) thin layer of loose structure that can penetrating aqueous vapor, upper surface TiO 2Or SiO 2Nano-powder carries out super-hydrophobic processing, but does not influence passing through of aqueous vapor.
Top three layers are attached on the dressing supporting layer with fenestration, and glue connects fixed layer with nonpoisonous polypropylene acid binding agent.Like this, obtain having the medical dressing of composite construction and complex function.

Claims (5)

1. the antibacterial medical dressing of a composite nano materials is characterized in that this dressing is made up of three one functional layer and one deck supporting layer, and ground floor is antibiotic layer (1), and this layer is to be undertaken compound by self-assembling method and nano anti-biotic material on the gauze layer; The second layer is hydrophilic layer (2), and this layer is by the method for hot dipping stain in conjunction with ultraviolet lighting, with the super hydrophilic treated of nano material work that is compounded on the gauze with gauze; The 3rd layer is hydrophobic layer (3), and this layer is the macromolecule thin layer with loose structure that can penetrating aqueous vapor, in the compound one deck nano material of this thin layer upper surface, does super-hydrophobic processing then, and outermost is supporting layer (4).
2. the antibacterial medical dressing of composite nano materials according to claim 1 is characterized in that nano anti-biotic material is for containing Ag +SiO 2The ZnO nanoparticle of nanoparticle or coated with silver on surface nano thin-layer.
3. the antibacterial medical dressing of composite nano materials according to claim 1 and 2 is characterized in that being compounded in that to make super material hydrophilic or super-hydrophobic processing on the gauze be TiO 2Or SiO 2Nano powder.
4. the antibacterial medical dressing of composite nano materials according to claim 1 and 2, the macromolecule thin layer that it is characterized in that having loose structure that can penetrating aqueous vapor is a polyurethane.
5. the antibacterial medical dressing of composite nano materials according to claim 1 and 2 is characterized in that the central authorities of supporting layer (4) have the window of being convenient to ventilate (41).
CNB01113643XA 2001-05-28 2001-05-28 Antibacterial medical dressing of composite nanometer material Expired - Fee Related CN1165347C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNB01113643XA CN1165347C (en) 2001-05-28 2001-05-28 Antibacterial medical dressing of composite nanometer material

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB01113643XA CN1165347C (en) 2001-05-28 2001-05-28 Antibacterial medical dressing of composite nanometer material

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CN1323635A true CN1323635A (en) 2001-11-28
CN1165347C CN1165347C (en) 2004-09-08

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101537204A (en) * 2008-03-18 2009-09-23 威海威高创新有限公司 Medical nanometer antibacterial composite dressing and method for preparing same
CN108403296A (en) * 2018-02-11 2018-08-17 郑州大学 A kind of two-sided anisotropic bandage and its manufacturing method based on electrostatic spinning process
CN109498271A (en) * 2018-12-21 2019-03-22 振德医疗用品股份有限公司 A kind of orientation imbibition prevents adhesion gauze and its manufacturing method
CN111821505A (en) * 2020-06-04 2020-10-27 东南大学 Super-paramagnetic nano-coating oral implant and preparation method thereof
CN114652899A (en) * 2022-04-12 2022-06-24 深圳职业技术学院 A self-growing artificial skin with antibacterial effect for burn, and its preparation method

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101537204A (en) * 2008-03-18 2009-09-23 威海威高创新有限公司 Medical nanometer antibacterial composite dressing and method for preparing same
CN101537204B (en) * 2008-03-18 2013-04-03 威海洁瑞医用制品有限公司 Medical nanometer antibacterial composite dressing and method for preparing same
CN108403296A (en) * 2018-02-11 2018-08-17 郑州大学 A kind of two-sided anisotropic bandage and its manufacturing method based on electrostatic spinning process
CN109498271A (en) * 2018-12-21 2019-03-22 振德医疗用品股份有限公司 A kind of orientation imbibition prevents adhesion gauze and its manufacturing method
CN109498271B (en) * 2018-12-21 2021-09-14 振德医疗用品股份有限公司 Directional liquid-absorbing anti-adhesion gauze and manufacturing method thereof
CN111821505A (en) * 2020-06-04 2020-10-27 东南大学 Super-paramagnetic nano-coating oral implant and preparation method thereof
CN114652899A (en) * 2022-04-12 2022-06-24 深圳职业技术学院 A self-growing artificial skin with antibacterial effect for burn, and its preparation method

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