CN109498271A - A kind of orientation imbibition prevents adhesion gauze and its manufacturing method - Google Patents
A kind of orientation imbibition prevents adhesion gauze and its manufacturing method Download PDFInfo
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- CN109498271A CN109498271A CN201811570927.3A CN201811570927A CN109498271A CN 109498271 A CN109498271 A CN 109498271A CN 201811570927 A CN201811570927 A CN 201811570927A CN 109498271 A CN109498271 A CN 109498271A
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- gauze
- contact layer
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- 238000005213 imbibition Methods 0.000 title claims abstract description 37
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 31
- 229920000742 Cotton Polymers 0.000 claims abstract description 99
- 239000002105 nanoparticle Substances 0.000 claims abstract description 50
- 238000011065 in-situ storage Methods 0.000 claims abstract description 25
- 230000006698 induction Effects 0.000 claims abstract description 24
- 238000000034 method Methods 0.000 claims abstract description 22
- 239000000203 mixture Substances 0.000 claims abstract description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 38
- 238000011049 filling Methods 0.000 claims description 34
- 239000007788 liquid Substances 0.000 claims description 30
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 27
- 239000000377 silicon dioxide Substances 0.000 claims description 22
- 235000012239 silicon dioxide Nutrition 0.000 claims description 17
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 claims description 16
- 239000000908 ammonium hydroxide Substances 0.000 claims description 16
- 239000002904 solvent Substances 0.000 claims description 16
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 15
- BOTDANWDWHJENH-UHFFFAOYSA-N Tetraethyl orthosilicate Chemical compound CCO[Si](OCC)(OCC)OCC BOTDANWDWHJENH-UHFFFAOYSA-N 0.000 claims description 15
- 239000004744 fabric Substances 0.000 claims description 11
- 238000005096 rolling process Methods 0.000 claims description 11
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- 208000027418 Wounds and injury Diseases 0.000 abstract description 15
- 206010052428 Wound Diseases 0.000 abstract description 14
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- 238000012986 modification Methods 0.000 description 6
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- 238000011160 research Methods 0.000 description 4
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 238000010521 absorption reaction Methods 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 239000000499 gel Substances 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 230000033115 angiogenesis Effects 0.000 description 2
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- 239000011248 coating agent Substances 0.000 description 2
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- 238000000151 deposition Methods 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- SCPWMSBAGXEGPW-UHFFFAOYSA-N dodecyl(trimethoxy)silane Chemical compound CCCCCCCCCCCC[Si](OC)(OC)OC SCPWMSBAGXEGPW-UHFFFAOYSA-N 0.000 description 2
- 210000000416 exudates and transudate Anatomy 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
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- 230000000474 nursing effect Effects 0.000 description 2
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- 229940099259 vaseline Drugs 0.000 description 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 1
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- 206010020649 Hyperkeratosis Diseases 0.000 description 1
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 1
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- 229920000297 Rayon Polymers 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 229920004933 Terylene® Polymers 0.000 description 1
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 1
- 208000031737 Tissue Adhesions Diseases 0.000 description 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical group O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 1
- 150000001335 aliphatic alkanes Chemical class 0.000 description 1
- 230000000181 anti-adherent effect Effects 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
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- 239000003610 charcoal Substances 0.000 description 1
- 235000015165 citric acid Nutrition 0.000 description 1
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- 238000007598 dipping method Methods 0.000 description 1
- YGUFXEJWPRRAEK-UHFFFAOYSA-N dodecyl(triethoxy)silane Chemical compound CCCCCCCCCCCC[Si](OCC)(OCC)OCC YGUFXEJWPRRAEK-UHFFFAOYSA-N 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000008169 grapeseed oil Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 229920001600 hydrophobic polymer Polymers 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
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- 238000002156 mixing Methods 0.000 description 1
- 239000002086 nanomaterial Substances 0.000 description 1
- 230000037311 normal skin Effects 0.000 description 1
- SLYCYWCVSGPDFR-UHFFFAOYSA-N octadecyltrimethoxysilane Chemical compound CCCCCCCCCCCCCCCCCC[Si](OC)(OC)OC SLYCYWCVSGPDFR-UHFFFAOYSA-N 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 238000000053 physical method Methods 0.000 description 1
- 239000004584 polyacrylic acid Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000001223 reverse osmosis Methods 0.000 description 1
- 238000001338 self-assembly Methods 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 238000003980 solgel method Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000003075 superhydrophobic effect Effects 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 230000010148 water-pollination Effects 0.000 description 1
- 238000009941 weaving Methods 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/01—Non-adhesive bandages or dressings
- A61F13/01021—Non-adhesive bandages or dressings characterised by the structure of the dressing
- A61F13/01029—Non-adhesive bandages or dressings characterised by the structure of the dressing made of multiple layers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/00987—Apparatus or processes for manufacturing non-adhesive dressings or bandages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/01—Non-adhesive bandages or dressings
- A61F13/01034—Non-adhesive bandages or dressings characterised by a property
- A61F13/01042—Absorbency
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M11/00—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereof; Such treatment combined with mechanical treatment, e.g. mercerising
- D06M11/77—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereof; Such treatment combined with mechanical treatment, e.g. mercerising with silicon or compounds thereof
- D06M11/79—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereof; Such treatment combined with mechanical treatment, e.g. mercerising with silicon or compounds thereof with silicon dioxide, silicic acids or their salts
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M2101/00—Chemical constitution of the fibres, threads, yarns, fabrics or fibrous goods made from such materials, to be treated
- D06M2101/02—Natural fibres, other than mineral fibres
- D06M2101/04—Vegetal fibres
- D06M2101/06—Vegetal fibres cellulosic
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Manufacturing & Machinery (AREA)
- Textile Engineering (AREA)
- Materials For Medical Uses (AREA)
- Absorbent Articles And Supports Therefor (AREA)
Abstract
It prevents adhesion gauze and its manufacturing method the invention discloses a kind of orientation imbibition, gauze includes: the contact layer for contacting wound, the absorbed layer on the outside of contact layer, and absorbed layer uses cotton gauze, and contact layer uses nanometer particle-modified cotton gauze；Nanometer particle-modified cotton gauze composition includes: cotton gauze ontology, the nanoparticle being fixed on cotton gauze ontology；Method of the invention carries out particle modified nano surface, induction in situ and low-surface-energy to cotton gauze contact layer and modifies, the contact layer with significantly hydrophobic performance is produced, it forms the gauze piece that wet structure is led with significant gradient with absorbed layer after compound, effectively increase the orientation imbibition ability of gauze；Modified gauze provides good ecological microenvironment for wound healing.
Description
Technical field
The present invention relates to field of medical materials, especially a kind of orientation imbibition prevents adhesion gauze and its manufacturing method.
Background technique
Medical cotton gauze is a kind of cotton goods that longitude and latitude is sparse, and cotton fiber is due to native cellulose ingredient, in strand
Containing a large amount of hydroxyl, good biocompatibility, moisture absorption are ventilative, have absorptive tissue liquid, debridement, thoroughly to human body wound and affected part
The functions such as gas, protection, it is a kind of ideal native biopolymer material that environmental protection is renewable.Medical absorbent cotton gauze is to defend material
One of leading products of industry, Treatment technique for processing is mature, is suitble to industrialized production, and at low cost, consumption is big, export volume
Greatly, modification and perfect performance on the basis of therefore processing for traditional cotton gauze have important economy and society meaning.
Traditional cotton gauze is inevitably present some defects in use.As conventional medical gauze absorbs surface of a wound table
After the diffusate in face, due to its preferable moisture absorption deposit it is moist, can be contacted with wound margin tissues, periphery normal skin tissue, cause yarn
Cloth moisture retention performance urging tissue and interfere cell Proliferation and angiogenesis, affect the quick healing of wound.In addition, conventional medical
Gauze is due to good biocompatibility, and surface pore structure is big, institutional framework is sparse, and histocyte is caused easily to grow into gauze and cause
The adhesion phenomenon of gauze surface and cambium.Therefore, it under the premise of not changing traditional raw material, is developed and is made by modified technique
A kind of medical cotton gauze with preferable imbibition wet transmitting performance and anti-cytoadherence performance is made, to productions such as broadening dressing, gauzes
The product category of enterprise increases added value and plays an important role.
The gauze that prevents adhesion of large-scale use is Vaseline gauze for medical use and oil gauze currently on the market, is to pass through leaching
Bubble vaseline oil and non-medication ointment play the role of preventing wound adhesion.It is cured according to state food pharmaceuticals administration general bureau
Instrument query result is treated, has no orientation imbibition anti-adhesion medical cotton gauze Related product at present.
Have the research and probe to orientation imbibition gauze dressing, mostly concentrate on combining using different hydrophilic, hydrophobic fibers,
It constructs composite construction and realizes one-way wet-guide, as the patent of 201710476 U of publication number CN 202620003 U and CN proposes respectively
Bamboo charcoal fiber cotton gauze and flaxen fiber is respectively adopted using the ventilative moisture conductive terylene fiber of cross and cotton blend gauze, bottom in surface layer
The composite gauze of cotton gauze；The first layer that the patent of publication number CN105597136A proposes uses viscose glue/polyester fiber non-woven fabric,
The second layer uses the composite gauze with hygroscopicity gradient of moisture-absorbing fibre non-woven fabrics manufacture；Publication number CN103655046A's
The non-woven fabrics being made of hydrophilic and hydrophobic fibre that patent proposes is made as contact layer and moisture absorption layer, hydrophobic fiber nonwoven fabric
For the dressing of the vertical wet guiding function of outermost layer composition.The above research has mostly used fibre in differentiation and hydrophily numerous in variety
The compound form manufacture of fibrous layer, requires gauze layer raw material sources high, process form complexity, in a short time unsuitable traditional cotton
Gauze dressing enterprise product updates.
Have the research and probe to the gauze dressing that prevents adhesion, mostly concentrates on using coating medicament, finish, or building gel
The modes such as layer prevent gauze and tissue adhesion, such as the patent point of publication number CN1058343, CN2668090 and CN102228717A
Not Cai Yong modified siloxane lotion, silicone oil and grape seed oil handle gauze, manufacture prevents adhesion gauze；Publication number CN1045354's
Patent manufactures the gauze that prevents adhesion using immersion treatments gauzes such as organic silicon emulsion, sulfonated castor oils；Publication number CN107375997A
Polyacrylic acid modified yarn is impregnated using Chinese medicine extract, sodium alginate, citric acid, glycerine etc. with the patent of CN107115553A
Cloth forms gel layer by freeze-drying and reaches antiseptic anti-adhesion effect.The above research is handled and is constructed gel layer using finish
It prevents tissue from growing into solution adhesion problems, but there are still the disadvantages of sepage is insufficient, gas permeability is bad is absorbed, affects gauze
The fast strikethrough of surface texture liquid.In addition, the patent of publication number CN102010515A is using sol-gel method on cotton gauze surface
Deposition of titanium oxide, self assembly introduce the perfluor Siloxane monolayers of low-surface-energy, manufacture with hydrophobic and oleophobic properties
Cotton hospital gauze；The patent of publication number CN103938432B is by the silicon dioxide granule and hydrophobic polymer of two kinds of different-grain diameters
Direct spraying constructs micro-nano structure coating in cotton gauze after mixing with auxiliary agent, obtains super-hydrophobic gauze.But above two
It is poor to there is particle stability in kind of technique, has the problems such as security risk.
As people are higher and higher to medical treatment and nursing level requirement, medicine instrument market needs one kind that can guarantee modified grain
Son gives full play to gauze surface layer hydrophobicity and anti-group in conjunction with fabric firm stable, and under the premise of not influencing gauze gas permeability
Blocking characteristics are knitted, while promoting the upgrading gauze of tissue fluid directional stream-guidance, the present invention solves such problems.
Summary of the invention
To solve the deficiencies in the prior art, it prevents adhesion gauze and its system the purpose of the present invention is to provide a kind of orientation imbibition
Method is made, the present invention carries out particle modified nano surface, induction in situ and low-surface-energy to cotton gauze contact layer and modifies, produces
Contact layer with significantly hydrophobic performance forms the gauze piece that wet structure is led with significant gradient with absorbed layer after compound,
Effectively increase the orientation imbibition ability of gauze；Modified gauze provides good ecological microenvironment for wound healing.
In order to achieve the above objectives, the present invention adopts the following technical scheme that:
A kind of orientation imbibition prevents adhesion gauze, comprising: the contact layer for contacting wound, the absorbed layer on the outside of contact layer,
Absorbed layer uses cotton gauze, and contact layer uses nanometer particle-modified cotton gauze；Nanometer particle-modified cotton gauze composition includes: cotton yarn
Cloth ontology, the nanoparticle being fixed on cotton gauze ontology.
A kind of orientation imbibition above-mentioned prevents adhesion gauze, and the yarn count of contact layer is less than the yarn count of absorbed layer, the warp of contact layer
Close and filling density is less than or equal to absorbed layer yarn through close and filling density.
A kind of orientation imbibition above-mentioned prevents adhesion gauze, and the cotton yarn yarn count of contact layer is 21-40s, and Jing Miwei 16-38 root/
In, filling density are 16-32 root/in；The cotton yarn yarn count of absorbed layer be 32-50s, Jing Miwei 26-38 root/in, filling density be 16-32 root/
In, the number of plies of contact layer are 1 layer, and the number of plies of absorbed layer is 3-8 layers.
A kind of orientation imbibition above-mentioned prevents adhesion gauze, and nanometer particle-modified gauze carries out surface using low surface energy auxiliary agent
Modification.
A kind of orientation imbibition above-mentioned prevents adhesion gauze, and nanoparticle is Nano particles of silicon dioxide, low surface energy auxiliary agent
For functionalization siloxanes.
A kind of orientation imbibition prevents adhesion the manufacturing method of gauze, includes the following steps:
Step 1 weaves contact layer and absorbed layer respectively,
The yarn count of the cotton gauze of contact layer is less than the yarn count of absorbed layer, and being less than or equal to through close and filling density for contact layer absorbs
Layer through close and filling density；
Step 2, with the cotton gauze of nanometer particle-modified contact layer,
Nano particles of silicon dioxide colloidal sol is prepared, gauze is handled through one immersing and rolling of Nano particles of silicon dioxide colloidal sol,
10-30min is dried at 100-120 DEG C, solidifies 3-10min at 140-160 DEG C, obtains the cotton yarn for being fixed with first order nanoparticle
Cloth；
Step 3 carries out induction in situ to the cotton gauze for being fixed with first order nanoparticle,
Modified gauze is dipped in 10-30min in induction liquid in situ at 30-50 DEG C by preparation induction liquid in situ, after cleaning,
10-30min is dried at 100-120 DEG C, solidifies 1-10min at 140-160 DEG C, obtains the cotton for being fixed with second level nanoparticle
Gauze；
Step 4, it is by congruent manner that contact layer and absorbed layer is compound using the unmodified cotton gauze of multilayer as absorbed layer
Together.
A kind of orientation imbibition prevents adhesion the manufacturing method of gauze, includes the following steps:
Step 1 weaves contact layer and absorbed layer respectively,
The yarn count of contact layer is less than the yarn count of absorbed layer, contact layer through close and filling density be less than or equal to absorbed layer through close
And filling density；
Step 2, with the cotton gauze of nanometer particle-modified contact layer,
Nano particles of silicon dioxide colloidal sol is prepared, gauze is handled through one immersing and rolling of Nano particles of silicon dioxide colloidal sol,
10-30min is dried at 100-120 DEG C, solidifies 3-10min at 140-160 DEG C, obtains the cotton yarn for being fixed with first order nanoparticle
Cloth；
Step 3 carries out induction in situ to the cotton gauze for being fixed with first order nanoparticle,
Modified gauze is dipped in 10-30min in induction liquid in situ at 30-50 DEG C by preparation induction liquid in situ, after cleaning,
10-30min is dried at 100-120 DEG C, solidifies 1-10min at 140-160 DEG C, obtains the cotton for being fixed with second level nanoparticle
Gauze；
Step 4 is surface modified modified contact layer with low surface energy auxiliary agent,
The ethanol hydrolysis liquid of 2-5V/V% functionalization siloxanes is configured, pH to 5-7 is adjusted, second level nanoparticle will be fixed with
The cotton gauze of son impregnates wherein 4-10h；
Step 5, it is by congruent manner that contact layer and absorbed layer is compound using the unmodified cotton gauze of multilayer as absorbed layer
Together.
A kind of orientation imbibition above-mentioned prevents adhesion the manufacturing method of gauze, and the partial size of first order nanoparticle is 20-
120nm, the partial size of second level nanoparticle are 80-500nm.
A kind of orientation imbibition above-mentioned prevents adhesion the manufacturing method of gauze, the method for preparing Nano particles of silicon dioxide colloidal sol
Are as follows: using dehydrated alcohol as solvent, 0.1-0.6mol/L tetraethyl orthosilicate, the ammonium hydroxide of 0.2-0.8mol/L, at 20-60 DEG C is added
At a temperature of, at the uniform velocity stir 20-100 minutes.
A kind of orientation imbibition above-mentioned prevents adhesion the manufacturing method of gauze, the method for preparing induction liquid in situ are as follows: with isopropyl
Alcohol is solvent, and 0.1-0.6mol/L tetraethyl orthosilicate is added, adds the ammonium hydroxide of 0.2-0.8mol/L.
The invention has the beneficial effects that:
It is modified 1. the present invention carries out particle modified nano surface, induction in situ and low-surface-energy to cotton gauze contact layer, system
The contact layer with significantly hydrophobic performance has been made, has formd the gauze for leading wet structure with significant gradient after compound with absorbed layer
Block effectively increases the orientation imbibition ability of gauze.After manufactured gauze is contacted with wound, quickly wound can be organized to ooze out
Liquid is absorbed and is shifted, avoid gauze due to moisture retention performance urging tissue, interfere cell Proliferation and the problem of angiogenesis.
Meanwhile the fast transfer of wound tissue exudates maintains the clinical debridement effect of wound height, protects between wound and gauze
It is wet wet without depositing, good microenvironment is provided for wound healing.
2. contact layer of the present invention forms multistage particle knot after induction nanometer particle-modified and in situ, in contact layer surface
Structure greatly improves the roughness of contact layer surface, then modifies the specific surface energy for reducing contact layer by low-surface-energy, so that
Gauze surface has the ability of significant anti-histocyte adherency, and it is thin to solve normal gauze use process Zhong Yi adhesion organization
The problem of born of the same parents, when removal, easily cause callus secondary injury；
3. in fiber surface auto polymerization occurs for nanoparticle of the cotton gauze contact layer after inducing, and is formed in situ poly-
Interlocked in siloxane layer, so as to improve gauze surface modified effect and with the pull-out capacity of gauze, compared to conventional nano grain
Son, the nanoparticle after inducing is stronger in conjunction with gauze and stablizes, and solves nanoparticle and is easy to take off in gauze surface
The security hidden trouble fallen；
4. the present invention, by modified technique and structure composite technology, opens under the premise of not changing traditional cotton gauze raw material
Hair manufacture has the medical cotton gauze of orientation imbibition and anti-cytoadherence dual property.Easy to operate, energy consumption is few, to dressing, yarn
The successive generations of products of Bu Deng manufacturing enterprise increases economic benefit and plays an important role, meanwhile, people have also been catered to high-end
The medical treatment and nursing demand of gauze product.
Detailed description of the invention
Fig. 1 is a kind of flow chart of embodiment of manufacturing method of the present invention；
Fig. 2 is aqueous water management system tester used in sample of the present invention and control sample unidirectional delivery index assessment
Test philosophy schematic diagram；
Fig. 3 is polytetrafluoroethylene (PTFE) mold schematic diagram of the invention；
Fig. 4 is the unidirectional delivery index schematic diagram of sample of the present invention and contrast sample；
Fig. 5 is the removing energy schematic diagram of sample of the present invention and contrast sample.
Specific embodiment
Specific introduce is made to the present invention below in conjunction with the drawings and specific embodiments.
A kind of orientation imbibition prevents adhesion gauze, comprising: the contact layer for contacting wound, the absorbed layer on the outside of contact layer,
Absorbed layer uses cotton gauze, and contact layer uses nanometer particle-modified cotton gauze；Nanometer particle-modified cotton gauze composition has: cotton gauze
Ontology, the nanoparticle being fixed on cotton gauze ontology.Nanometer particle-modified cotton gauze carries out surface using low surface energy auxiliary agent
Modification.As a preference, nanoparticle is Nano particles of silicon dioxide, low surface energy auxiliary agent is functionalization siloxanes, as
A kind of embodiment, functionalization siloxanes include: the siloxanes containing long chain alkane, dodecyltrimethoxysilane, cetyl
Trimethoxy silane, octadecyl trimethoxysilane, dodecyl triethoxysilane.
The yarn count of contact layer is less than the yarn count of absorbed layer, contact layer through close and filling density be less than or equal to absorbed layer through close
And filling density.Gradient is formed after contact layer and absorbed layer are compound and leads wet structure, effectively increases the orientation imbibition ability of gauze.As
A kind of embodiment, the cotton yarn yarn count of contact layer are 21-40s, and Jing Miwei 16-38 root/in, filling density is 16-32 root/in；Absorbed layer
Cotton yarn yarn count be 32-50s, Jing Miwei 26-38 root/in, filling density be 16-32 root/in；The contact layer number of plies is 1 layer, is absorbed layer by layer
Number is 3-8 layers.Structure as contact layer and absorbed layer designs to form gradient-structure, effectively increases the oriented moisture transfer energy of gauze
Power.
A kind of orientation imbibition prevents adhesion the manufacturing method of gauze, includes the following steps:
Step 1 weaves contact layer and absorbed layer respectively,
The yarn count of contact layer is less than the yarn count of absorbed layer, contact layer through close and filling density be less than or equal to absorbed layer through close
And filling density；As one embodiment, the cotton yarn yarn count of contact layer is 21-40s, Jing Miwei 16-38 root/in, filling density 16-32
Root/in；The cotton yarn yarn count of absorbed layer is 32-50s, Jing Miwei 26-38 root/in, and filling density is 16-32 root/in；The contact layer number of plies is
1 layer, the absorbed layer number of plies is 3-8 layers.
Step 2, with the cotton gauze of nanometer particle-modified contact layer,
Nano particles of silicon dioxide colloidal sol is prepared, gauze is handled through one immersing and rolling of Nano particles of silicon dioxide colloidal sol,
10-30min is dried at 100-120 DEG C, solidifies 3-10min at 140-160 DEG C, obtains the cotton yarn for being fixed with first order nanoparticle
Cloth；
The method for preparing Nano particles of silicon dioxide colloidal sol are as follows: using dehydrated alcohol as solvent, 0.1-0.6mol/L is being added just
Tetraethyl orthosilicate, the ammonium hydroxide of 0.2-0.8mol/L, 20-60 DEG C at a temperature of, at the uniform velocity stir 20-100 minutes.
Step 3 carries out induction in situ to the cotton gauze for being fixed with first order nanoparticle,
Modified gauze is dipped in 10-30min in induction liquid in situ at 30-50 DEG C by preparation induction liquid in situ, after cleaning,
10-30min is dried at 100-120 DEG C, solidifies 1-10min at 140-160 DEG C, obtains the cotton for being fixed with second level nanoparticle
Gauze；
The method of preparation induction liquid in situ are as follows: using isopropanol as solvent, 0.1-0.6mol/L tetraethyl orthosilicate is added, then
The ammonium hydroxide of 0.2-0.8mol/L is added.
Step 4 is surface modified modified contact layer with low surface energy auxiliary agent,
The ethanol hydrolysis liquid for configuring 2-5V/V% functionalization siloxanes adjusts pH to 5-7 with 1M HCl, will be fixed with second
The cotton gauze of grade nanoparticle impregnates wherein 4-10h；The present invention is surface modified nanometer particle-modified contact layer, is contacting
On the basis of the existing nanoparticle of layer, the specific surface energy of contact layer surface is significantly reduced, the hydrophobic effect of cotton gauze is enhanced
And anti-adhesion effect.
Step 5, it is by congruent manner that contact layer and absorbed layer is compound using the unmodified cotton gauze of multilayer as absorbed layer
Together.
Experimental verification:
According to following embodiment, sample 1, sample 2, sample 3, contrast sample 1, contrast sample 2, contrast sample 3 are produced.
Embodiment 1, manufacturing process are as follows:
Weave yarn count 21s respectively, warp, 16 × 16/in of filling density degreasing cotton gauze as contact layer, yarn count 32s, through,
The degreasing cotton gauze of 26 × 18/in of filling density is as absorbed layer；
Using dehydrated alcohol as solvent, 0.4mol/L tetraethyl orthosilicate, the ammonium hydroxide of 0.4mol/L, in 50 DEG C of temperature is added
Under, it at the uniform velocity stirs 80 minutes, prepares SiO2Colloidal sol, colloidal sol use preceding ultrasonic disperse 8min, contact layer immersing and rolling in colloidal sol
Afterwards, 15min is dried at 110 DEG C, solidify 3min at 140 DEG C；
Using isopropanol as solvent, 0.4mol/L tetraethyl orthosilicate is added, the ammonium hydroxide of 0.4mol/L is added, at 50 DEG C
Above-mentioned gauze is dipped in wherein 20min, is dried after cleaning, solidifies 1min at 140 DEG C；
The ethanol hydrolysis liquid for configuring 5V/V% dodecyltrimethoxysilane adjusts pH to 6.5 with 1M HCl, will be above-mentioned
Gauze impregnates wherein 10h after processing, dries to obtain contact layer；
1 layer of treated contact layer is combined with 8 layers of untreated absorbed layer by overlapping.
Embodiment 2, manufacturing process are as follows:
Weave yarn count 21s respectively, warp, 26 × 18/in of filling density degreasing cotton gauze as contact layer, yarn count 40s, through,
The degreasing cotton gauze of 26 × 18/in of filling density is as absorbed layer；
Using dehydrated alcohol as solvent, 0.4mol/L tetraethyl orthosilicate, 0.3mol/L ammonium hydroxide, in 40 DEG C of temperature is added
Under, it at the uniform velocity stirs 60 minutes, prepares SiO2Colloidal sol, colloidal sol use preceding ultrasonic disperse 5min, contact layer immersing and rolling in colloidal sol
Afterwards, 15min is dried at 100 DEG C, solidify 5min at 150 DEG C；
Using isopropanol as solvent, 0.4mol/L tetraethyl orthosilicate is added, the ammonium hydroxide of 0.5mol/L is added, at 50 DEG C
Above-mentioned gauze is dipped in wherein 15min, is dried after cleaning, solidifies 1min at 150 DEG C；
The ethanol hydrolysis liquid for configuring 3V/V% hexadecyl trimethoxy silane adjusts pH to 6.0 with 1M HCl, will be above-mentioned
Gauze impregnates wherein 6h after processing, dries.
1 layer of treated gauze is combined with 5 layers of untreated absorbed layer degreasing cotton gauze by overlapping.
Embodiment 3, manufacturing process are as follows:
The cotton yarn yarn count of contact layer be 40s, warp, 38 × 32/in of filling density degreasing cotton gauze as contact layer；Yarn count
50s, warp, 38 × 32/in of filling density degreasing cotton gauze as absorbed layer；
Using dehydrated alcohol as solvent, 0.4mol/L tetraethyl orthosilicate, 0.3mol/L ammonium hydroxide, in 50 DEG C of temperature is added
Under, it at the uniform velocity stirs 60 minutes, prepares SiO2Colloidal sol, colloidal sol use preceding ultrasonic disperse 8min, contact layer immersing and rolling in colloidal sol
Afterwards, 15min is dried at 110 DEG C, solidify 3min at 140 DEG C；
Using isopropanol as solvent, 0.4mol/L tetraethyl orthosilicate is added, the ammonium hydroxide of 0.6mol/L is added, at 50 DEG C
Above-mentioned gauze is dipped in wherein 20min, is dried after cleaning, solidifies 1min at 140 DEG C；
The ethanol hydrolysis liquid for configuring 4V/V% hexadecyl trimethoxy silane adjusts pH to 6.5 with 1M HCl, will be above-mentioned
Gauze impregnates wherein 10h after processing, dries.
1 layer of treated gauze is combined with 8 layers of untreated absorbed layer degreasing cotton gauze by overlapping.
Comparative example 1, manufacturing process are as follows:
Respectively weave yarn count 40s, warp, 26 × 18/in of filling density degreasing cotton gauze be used as contact layer, weaving yarn count 40s,
Degreasing cotton gauze through, 26 × 18/in of filling density is as absorbed layer；Contact layer and absorbed layer use identical gauze；
Using dehydrated alcohol as solvent, addition 0.4mol/L tetraethyl orthosilicate, 0.7mol/L ammonium hydroxide, at room temperature, at the uniform velocity
Stirring 60 minutes prepares SiO2Colloidal sol.Contact layer after second dipping and rolling, is placed at room temperature for for 24 hours in colloidal sol；
The ethanol hydrolysis liquid for configuring 4V/V% hexadecyl trimethoxy silane adjusts pH to 6.5 with 1M HCl, will be above-mentioned
Gauze impregnates wherein 10h after processing, dries.
1 layer of treated gauze is combined with 8 layers of untreated absorbed layer degreasing cotton gauze by overlapping.
Comparative example 2, manufacturing process are as follows:
Weave yarn count 21s respectively, warp, 26 × 18/in of filling density degreasing cotton gauze as contact layer, yarn count 21s, through,
The degreasing cotton gauze of 26 × 18/in of filling density is as absorbed layer；
Using dehydrated alcohol as solvent, 0.4mol/L tetraethyl orthosilicate, 0.3mol/L ammonium hydroxide, in 50 DEG C of temperature is added
Under, it at the uniform velocity stirs 60 minutes, prepares SiO2Colloidal sol, colloidal sol use preceding ultrasonic disperse 8min, contact layer immersing and rolling in colloidal sol
Afterwards, 15min is dried at 110 DEG C, solidify 3min at 140 DEG C；
The ethanol hydrolysis liquid for configuring 4V/V% hexadecyl trimethoxy silane adjusts pH to 6.5 with 1M HCl, will be above-mentioned
Gauze impregnates wherein 10h after processing, dries；
1 layer of treated gauze is combined together with 8 layers of untreated absorbed layer degreasing cotton gauze by physical method.
Comparative example 3, manufacturing process are as follows:
Weave yarn count 21s respectively, warp, 26 × 18/in of filling density degreasing cotton gauze as contact layer, yarn count 40s, through,
The degreasing cotton gauze of 26 × 18/in of filling density is as absorbed layer；
Using dehydrated alcohol as solvent, 0.4mol/L tetraethyl orthosilicate, 0.3mol/L ammonium hydroxide, in 50 DEG C of temperature is added
Under, it at the uniform velocity stirs 60 minutes, prepares SiO2Colloidal sol, colloidal sol use preceding ultrasonic disperse 8min, contact layer immersing and rolling in colloidal sol
Afterwards, 15min is dried at 110 DEG C, solidify 3min at 140 DEG C；
Using isopropanol as solvent, 0.4mol/L tetraethyl orthosilicate is added, the ammonium hydroxide of 0.6mol/L is added, at 50 DEG C
Above-mentioned gauze is dipped in wherein 20min, is dried after cleaning, solidifies 1min at 140 DEG C；
The ethanol hydrolysis liquid for configuring 4V/V% hexadecyl trimethoxy silane adjusts pH to 6.5 with 1M HCl, will be above-mentioned
Gauze impregnates wherein 10h after processing, dries.
2 layers of treated gauze are combined with each other with 5 layers of untreated absorbed layer degreasing cotton gauze by congruent manner.
According to above embodiments, sample 1, sample 2, sample 3, contrast sample 1, contrast sample 2, contrast sample 3 are produced.
Compliance test result experiment is carried out with the following method；
Experiment one, unidirectional delivery index are used to evaluate the orientation absorbent of gauze, test method are as follows:
According to GB/T 21655.2-2009, using the M290 liquid water of tin Lay Asia-Pacific Shanghai branch company, Lars Co., Ltd
It is in charge of the unidirectional delivery index of reason system controller test gauze, test schematic diagram is as shown in Figure 2.Gauze forward direction is (from contact layer
To absorbed layer) unidirectional delivery index is bigger, it more can quickly absorb liquid；The reversely unidirectional delivery index (from absorbed layer to contact layer)
Negative value is bigger, is less susceptible to that reverse osmosis occurs.Therefore, forward and reverse transitive index difference is bigger, and the orientation absorbent of gauze is better.
Experimental situation: sample damping in the environment of temperature is (21 ± 1) °, relative humidity (65 ± 2) % reaches flat for 24 hours
Weighing apparatus.Sample size is 9cm × 9cm.
Experimental result is as shown in table 1 and Fig. 4:
The unidirectional delivery index of 1 sample of table and contrast sample
Interpretation of result:
List (just) of the sample gauze produced with method of the invention from contact layer to absorbed layer is big to transitive index,
And it is also big to contact layer list (anti-) to transitive index negative value from absorbed layer, not only liquid can be transmitted rapidly and is not susceptible to anti-
It seeps.Therefore, the orientation absorbent of gauze is outstanding；Lack induction liquid modification procedure in situ and is not designed according to structure of the invention
The contrast sample gauze being combined with each other, forward and reverse transitive index difference is significantly less than the sample yarn that the method for the present invention produces
Forward and reverse transitive index difference of cloth, orientation absorbent are poor.
Experiment two, external anti-blocking properties test method are as follows:
The gauze of 3cm × 15cm is immersed into 5min in deionized water, is then laid on clean surface, and will have
Polytetrafluoroethylene (PTFE) (PTFE) mold of 60mm × 16mm opening is placed on it.Polytetrafluoroethylene (PTFE) (PTFE) mold is as shown in Figure 2.
In order to simulate Wound exudate to the adhesiveness of gauze, with 70 DEG C of deionized water preparation 40w% gelatin and pour into
In PTFE mold.Then by gelatin/gauze module be placed in 20 DEG C, in the environment of 65% humidity for 24 hours.With the removing of gelatin and gauze
Power characterizes anti-blocking properties.
Peel test force is by HD026N-300 multifunctional fabric strength machine, under 90 ° of peel angles, with 100 (mm/
Min constant rate of speed peel sample) is completed.Average load needed for record removal gauze, the removing of unit of account area can θ
=2P/b, wherein P is Average peel force (N), and b is gelatin width (0.016m), and removing energy unit is J/m2.Gauze removes energy
Smaller, anti-blocking properties are better.
Shown in experimental result table 2 and Fig. 5.
The removing energy of 2 sample of table and contrast sample
| Sample | Sample 1 | Sample 2 | Sample 3 | Comparative sample 1 | Comparative sample 2 | Comparative sample 3 |
| Removing can (J/m2) | 187.50 | 121.67 | 219.38 | 302.50 | 296.88 | 282.50 |
| Standard deviation | 8.09 | 13.46 | 13.23 | 7.71 | 2.17 | 13.23 |
Interpretation of result:
The removing of the sample gauze produced with method of the invention can be smaller, has to tissue protein good
Anti-adhesive properties.And lacks induction liquid modification procedure in situ and do not design the contrast sample being combined with each other according to structure of the invention
The removing of gauze can be larger, and anti-blocking properties are poor compared to the sample that method of the invention produces.
The present invention provides a kind of orientation imbibition and prevents adhesion gauze and its manufacturing method, and the present invention carries out cotton gauze contact layer
Nano surface is particle modified, original position induces and low-surface-energy modification, the contact layer with significantly hydrophobic performance has been produced, with suction
The gauze piece for leading wet structure with significant gradient is formd after receipts layer is compound, effectively increases the orientation imbibition ability of gauze.
The basic principles, main features and advantages of the invention have been shown and described above.The technical staff of the industry should
Understand, the above embodiments do not limit the invention in any form, all obtained by the way of equivalent substitution or equivalent transformation
Technical solution is fallen within the scope of protection of the present invention.
Claims (10)
- The gauze 1. a kind of orientation imbibition prevents adhesion characterized by comprising contact the contact layer of wound, be located on the outside of contact layer Absorbed layer, the absorbed layer use cotton gauze, the contact layer use nanometer particle-modified cotton gauze；The nanoparticle changes The composition of property cotton gauze includes: cotton gauze ontology, the nanoparticle being fixed on cotton gauze ontology.
- The gauze 2. a kind of orientation imbibition according to claim 1 prevents adhesion, which is characterized in that the yarn count of the contact layer is small In the yarn count of absorbed layer, contact layer through close and filling density be less than or equal to absorbed layer through close and filling density.
- The gauze 3. a kind of orientation imbibition according to claim 2 prevents adhesion, which is characterized in that the cotton yarn yarn of the contact layer Branch is 21-40s, and Jing Miwei 16-38 root/in, filling density is 16-32 root/in；The cotton yarn yarn count of absorbed layer is 32-50s, Jing Miwei 26-38 root/in, filling density are 16-32 root/in；The number of plies of the contact layer is 1 layer, and the number of plies of absorbed layer is 3-8 layers.
- The gauze 4. a kind of orientation imbibition according to claim 1 prevents adhesion, which is characterized in that the nanometer particle-modified cotton Gauze is surface modified using low surface energy auxiliary agent.
- The gauze 5. a kind of orientation imbibition according to claim 4 prevents adhesion, which is characterized in that the nanoparticle is dioxy SiClx nanoparticle, the low surface energy auxiliary agent are functionalization siloxanes.
- The manufacturing method of gauze 6. a kind of orientation imbibition prevents adhesion, which comprises the steps of:Step 1 weaves contact layer and absorbed layer respectively,The yarn count of contact layer is less than the yarn count of absorbed layer, contact layer through close and filling density be less than or equal to absorbed layer through close and latitude It is close；Step 2, with the cotton gauze of nanometer particle-modified contact layer,Nano particles of silicon dioxide colloidal sol is prepared, gauze is handled through one immersing and rolling of Nano particles of silicon dioxide colloidal sol, in 100-120 10-30min is dried at DEG C, solidifies 3-10min at 140-160 DEG C, obtains the cotton gauze for being fixed with first order nanoparticle；Step 3 carries out induction in situ to the cotton gauze for being fixed with first order nanoparticle,Modified gauze is dipped in 10-30min in induction liquid in situ at 30-50 DEG C by preparation induction liquid in situ, after cleaning, 10-30min is dried at 100-120 DEG C, solidifies 1-10min at 140-160 DEG C, obtains the cotton yarn for being fixed with second level nanoparticle Cloth；Contact layer and absorbed layer are compounded in one by congruent manner using the unmodified cotton gauze of multilayer as absorbed layer by step 4 It rises.
- The manufacturing method of gauze 7. a kind of orientation imbibition prevents adhesion, which comprises the steps of:Step 1 weaves contact layer and absorbed layer,The yarn count of contact layer is less than the yarn count of absorbed layer, contact layer through close and filling density be less than or equal to absorbed layer through close and latitude It is close；Step 2, with nanometer particle-modified contact layer,Nano particles of silicon dioxide colloidal sol is prepared, gauze is handled through one immersing and rolling of Nano particles of silicon dioxide colloidal sol, in 100-120 10-30min is dried at DEG C, solidifies 3-10min at 140-160 DEG C, obtains the cotton gauze for being fixed with first order nanoparticle；Step 3 carries out induction in situ to the cotton gauze for being fixed with first order nanoparticle,Modified gauze is dipped in 10-30min in induction liquid in situ at 30-50 DEG C by preparation induction liquid in situ, after cleaning, 10-30min is dried at 100-120 DEG C, solidifies 1-10min at 140-160 DEG C, obtains the cotton yarn for being fixed with second level nanoparticle Cloth；Step 4 is surface modified modified contact layer with low surface energy auxiliary agent,The ethanol hydrolysis liquid of 2-5V/V% functionalization siloxanes is configured, pH to 5-7 is adjusted, second level nanoparticle will be fixed with Cotton gauze impregnates wherein 4-10h；Contact layer and absorbed layer are compounded in one by congruent manner using the unmodified cotton gauze of multilayer as absorbed layer by step 5 It rises.
- The manufacturing method of gauze 8. a kind of orientation imbibition according to claim 6 or 7 prevents adhesion, which is characterized in that described The partial size of first order nanoparticle is 20-120nm, and the partial size of second level nanoparticle is 80-500nm.
- The manufacturing method of gauze 9. a kind of orientation imbibition according to claim 6 or 7 prevents adhesion, which is characterized in that described The method for preparing Nano particles of silicon dioxide colloidal sol are as follows: using dehydrated alcohol as solvent, the positive silicic acid tetrem of 0.1-0.6mol/L is added Ester, the ammonium hydroxide of 0.2-0.8mol/L, 20-60 DEG C at a temperature of, at the uniform velocity stir 20-100 minutes.
- The manufacturing method of gauze 10. a kind of orientation imbibition according to claim 6 or 7 prevents adhesion, which is characterized in that described The method of preparation induction liquid in situ are as follows: using isopropanol as solvent, 0.1-0.6mol/L tetraethyl orthosilicate is added, adds 0.2- The ammonium hydroxide of 0.8mol/L.
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| CN110393632A (en) * | 2019-07-17 | 2019-11-01 | 稳健医疗用品股份有限公司 | A kind of water repellency dressing and preparation method thereof |
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