CN1323626A - Traditional Chinese medicine prepn. for raising male's sexual function - Google Patents

Abstract

The present inventino relates to a treational Chinese medicinal preparation for enhancing male secual function, it is made from 15 traditional Chinese medicinal materials including testiset penis phocae, deer penis, corna cervi pantotrichum, donkey penis, yellow dog penis, ginseng, Chinese wolfberrry fruit, fructus corni, cordyceps, herbe epimedii, radix polggoni multiflori, astragalus root, acanthopanax root, poriaa, honey through processing technology. It is low in toxic side action, can improve the excretion of sexual gland, delay sanility etc..

Description

A kind of Chinese medicine preparation that improves male's sexual

The present invention relates to the medicine of kidney invigorating and YANG supporting, exactly is to disclose a kind of Chinese medicine preparation that improves male's sexual, belongs to traditional Chinese medical science pharmaceutical technology field.

Sexual hypofunction mainly is meant between twenty and fifty period of man, owing to reason such as deficient, terrified or damp and hot, cause penis lose to support and relax vertical, cause a little less than penis withers and do not rise, facing the room lifts and not hard disease, the medicine of kidney invigorating and YANG supporting is more on the market, medicine commonly used adopts famous and precious Chinese herbal medicine mostly, and the medicine cost is higher, and patient economy burden is excessive, curative effect is not remarkable yet, and specially control and suffer from a deficiency of the kidney, simple the kidney invigorating, too warm-dryness syndrome, should not obey for a long time, the slow-witted benefit of result is invalid, even the medicine that has also has very big toxic and side effects.

The invention provides a kind of Chinese medicine preparation that improves male's sexual, purpose is to solve above shortcomings in the treatment male sexual disorder.

For achieving the above object, the present invention is according to pathogenesis and the Therapeutic Principle of motherland's traditional Chinese medical science traditional theory to this disease, in conjunction with the modern medicine achievement, selected Chinese herbal medicine and rare animal with benefiting qi and nourishing blood, life essence-filling, marrow-benefitting, kidney and spleen invigorating function, make pharmaceutical preparation through science, be used for kidney invigorating and YANG supporting, improve male's sexual.

Medicine of the present invention is made (by ratio of weight and the number of copies) by following component:

Testis et penis callorhini 1～3, Penis et testis cervi 5～15, Cornu Cervi Pantotrichum 5～15, Testis Et penis Equi 5～15,

Penis et Testis Canis 45～55, Radix Ginseng 45～55, Fructus Lycii 45～55, Fructus Corni 45～55,

Cordyceps 15～25, Herba Epimedii 45～55, Radix Polygoni Multiflori 45～55, the Radix Astragali 45～55,

Radix Et Caulis Acanthopanacis Senticosi 45～55, Poria 45～55, Mel 45～55.

Optimum ratio of the present invention is (by ratio of weight and the number of copies):

Testis et penis callorhini 2, Penis et testis cervi 10, Cornu Cervi Pantotrichum 10, Testis Et penis Equi 10, Penis et Testis Canis 50,

Radix Ginseng 50, Fructus Lycii 50, Fructus Corni 50, Cordyceps 20,

Herba Epimedii 50, Radix Polygoni Multiflori 50, the Radix Astragali 50, Radix Et Caulis Acanthopanacis Senticosi 50,

Poria 50, Mel 50.

Above-mentioned prescription is concocted by traditional Chinese medicine oral liquid, concrete technology is as follows: will add the water of 1/2～2/3 total umber in the above-mentioned raw materials, decoct 2～3 times, decocting time is 1.5～2.5 hours, and decocting liquid filters, and being concentrated into relative density with the Mel mediation is 1.0～1.3, pH value is 5.0～6.0, boil the filtrate packing, steam high temperature sterilize 40 minutes gets oral liquid of the present invention.

The present invention also makes said dosage form on any pharmaceutics.

The present invention is a monarch drug with the Testis et penis callorhini, and salty in the mouth is gone into kidney channel, and special supporing yang unit and invigorating kidney-YANG are the sterile key medicine of treatment sexual impotence, are equipped with the product of Penis et testis cervi, Cornu Cervi Pantotrichum, Penis et Testis Canis, Testis Et penis Equi flesh and blood friendship, and People of the same tastes and habits like to be together, mends the gate of vitality, invigorating kidney-YANG, and benefiting essence-blood, bone and muscle strengthening, accent is filled the post of; Must join the sweet temperature of Fructus Lycii and acid, nourishing the liver and kidney, benefiting essence and marrow is to reach the purpose of coordination of YIN and YANG; Cordyceps lung benefiting kidney is mended marrow, mutual generation between metal and water; Herba Epimedii suffering, sweet, warm is mended the gate of vitality, beneficial vital essence, and hard muscles and bones, diuresis, for exhausted sun is out of fashion, the medicine that exhausted the moon does not produce makes the medicine-feeding tonify without causing stagnation; The hot temperature of Radix Et Caulis Acanthopanacis Senticosi is gone into Liver and kidney, strengthening bone and muscle, and blood circulation promoting and blood stasis dispelling, benefit is smart; The bitter miniflow of the sweet temperature of the Radix Ginseng Radix Astragali, sweet invigorating middle warmer, warm physical strength profiting, the hardship miniflow that purges heat is promptly not dry, strongly invigorating primordial QI, harmonizing yingfen and weifen, it is bright directly to get sun, building up the spleen to supplement the lung water, temperature is not and dry, and happy Fructus Alpiniae Oxyphyllae helps god, adds spirit, promoting blood circulation, YIN and YANG in a relative equilibrium then; Radix Polygoni Multiflori is cloudy middle-jiao yang, function of the spleen and stomach medicine, beneficial blood, and acid is mended congenital Kidney-Yin, transfers again and mends the nutrient blood day after tomorrow, gets rid of illness and transfers unit, with the mistake of assistant the monarch and his subjects benefit; Urosolic acid is held back tonifying YIN and is made warm-dryness syndrome, and the Poria slightly sweet flavor oozes, invigorating the spleen and replenishing QI; Above-mentioned all medicines are harmonious, and play altogether and mend gate of vitality's liver and kidney tonifying and Yang Ming, the tonifying YANG road, the consolidating YIN stem adds smart seed, and then negative and positive are coordinated, and spirit is not disobeyed, and mechanism of qi is unimpeded, and if body is one effect.

Instructions of taking: every day is once oral, and each one (10ml), two weeks were a course of treatment.

Characteristics of the present invention are: make with natural rare, pure Chinese herbal medicine, toxic and side effects is little, and treating both the principal and secondary aspects of a disease does not contain the synthetic hormone, do not contain morphine, cocaine and emerging positive fillip, promote the gonad secretion, strengthen sexual function, reduce tired, improve the body vigor, tonifying YANG fast in the Time of Administration prolongs sexual life, prevents premature ejaculation, evident in efficacy, take invigorating the liver and kidney for a long time, benefit marrow, QI invigorating and blood producing, nourishing blood to tranquillize the mind, help the recovery of whole body function, receive that the kidney invigorating is also few, function in delaying senility.

For therapeutic effect of the present invention is described, observe through 100 routine male's clinical case histories, age is in 12 examples of person below 30 years old, 31～40 years old person's 36 example, 41～50 years old person's 27 example, 51～60 years old person's 17 examples, person's 8 examples more than 61 years old, the course of disease 1 year with interior person's 10 examples, 1～2 year person's 57 example, 3～4 years person's 19 examples, person's 14 examples more than 5 years.

The case history choice criteria: adopt national combination of Chinese and Western medicine deficient syndrome in 1986 and senile disease meeting deficient syndrome reference standard by deficiency of kidney-essence, sexual hypofunction, sexual impotence, seminal emission, premature ejaculation person due to the decline of the fire from the gate of life all can be used as the clinical research object.

Clinical observation: all out-patients that reaches in hospital who meets the case choice criteria all can be used as the clinical observation object, observing the doctor needs to fill in symptom and sign by the observation plan requirement, check blood simultaneously, routine urinalysis, liver function, immunoglobulin (30 example), 24 hours 17-hydroxyls, 17-ketone (30 example), testosterone (40 example) two weeks are a course of treatment, every day is once oral, each one (10ml), course of treatment is healing person not, can continue and obey a course of treatment, stop using other about strengthening by means of tonics medicine during taking this medicine, treatment finishes the back comprehensive review, adopt the method for treatment front and back own control, carry out statistical procedures with t check and rank test method.

The symptom curative effect:

Produce effects: 3 produce effects of cardinal symptom add 2 improvements; 4 produce effects add 1 invalid; 2 produce effects add 3 improvements.(+++～+、+++、++、+～-)；

Effectively: 1 produce effects of cardinal symptom adds 2 improvements, takes a turn for the better more than 3.(+++～++、++～+)；

Invalid: 3 above no changes of cardinal symptom.

Observed result: 100 routine clinical disease curative effects:

		Before taking medicine	After taking medicine	The U value	The P value
						Hyposexuality	????+++	???24	???1	??9.28	??＜0.001
????++	???46	???7
			????+	???21	???32
?????-	???9	???60
			Seminal emission	?????+++	???1		???0	??9.08	??＜0.001
?????++	???6	???0
				?????+	???23	???8
?????-	???68	???92
				Sexual impotence	?????+++	???9	???1			??6.92	??＜0.001
?????++	???41	???7
			?????+		???26	???26
?????-	???24	???66
			Premature ejaculation		?????+++	???2	???0	??5.12	??＜0.001
?????+++	???13	???1
				?????+	???31	???13
?????-	???54	???86
				Soreness of the waist and knees	?????+++	???18	???2			??9.19	??＜0.001
?????++	???36	???3
			?????+		???40	???33
?????-	???6	???62

Spiritlessness and weakness	????+++	????13	????0	??9.10	??＜0.001
						????++	????37	????6
	????+	????44	????31
						????-	????6	????63
	Have a dizzy spell	????+++	????9						????0	??6.37	??＜0.001
????++				????29	????2
		????+	????29			????19
????-				????33	????79
		Hiccough and deaf	????+++			????6	????0	??4.70	??＜0.001
????++	????22			????1
			????+		????20	????20
????-	????52			????79

The comparison of twenty-four-hour urine 17-hydroxyl, 17-ketone and testosterone influence before and after the 30 example treatments:

	Twenty-four-hour urine 17-hydroxyl	Twenty-four-hour urine 17-ketone	Testosterone
				Before the medication	????4.61±0.78	????11.46±1.27	????5.503±2.013
After the medication	????4.96±0.75	????12.87±1.69	????7.577±2.530
				??t	???????5.05	????????5.48	????????5.33
??P	???????＜0.01	????????＜0.01	????????＜0.01

Can improve 24 hours 17-hydroxyl of patient, 17-ketone level after as seen last table takes medicine, the effect of tangible promotion gonadal hormone secretion is arranged.

The influence of 30 routine immunoglobulins:

	????IgA	????IgG	????IgM	????Ca
					Before taking medicine	?1.41±1.07	11.92±6.21	?1.73±1.64	?0.98±0.30
After taking medicine	?1.60±0.86	14.93±7.00	?2.56±1.40	?1.24±0.21
					??T	????3.78	????2.71	????4.22	????4.67
??P	????＜0.01	????＜0.01	????＜0.01	????＜0.01

The effect of obvious raise immunity is arranged.

Comprehensive therapeutic effect: produce effects has 62 examples, is 61.22%; Effective 36 examples are 36.73%; Invalid 2 examples are 2.04%.

By 100 routine deficiency of kidney-essence, order the decline clinical observation of disease of fiery void, total effective rate is 97.96%, obvious effective rate 61.22% illustrates hyposexuality, seminal emission, premature ejaculation, sexual impotence, soreness of the waist and knees, spiritlessness and weakness that the present invention causes deficiency of kidney-YANG syndrome, has a dizzy spell, symptom such as Hiccough and deaf is evident in efficacy.

Embodiment 1

Get Testis et penis callorhini 2kg, Penis et testis cervi 10kg, Cornu Cervi Pantotrichum 10kg, Testis Et penis Equi 10kg, Penis et Testis Canis 50kg, Radix Ginseng 50kg, Fructus Lycii 50kg, Fructus Corni 50kg, Cordyceps 20kg, Herba Epimedii 50kg, Radix Polygoni Multiflori 50kg, Radix Astragali 50kg, Radix Et Caulis Acanthopanacis Senticosi 50kg, Poria 50kg.With adding 300kg water in the above-mentioned raw materials, decoct 3 times, decocting time is 2 hours, decocting liquid filters, being concentrated into relative density with Mel 50kg mediation is 1.0～1.3, and pH value is 5.0～6.0, boils the filtrate packing, in the oral liquid bottle of 10ml, steam high temperature sterilize 40 minutes gets oral liquid of the present invention.

Claims (3)

1, a kind of Chinese medicine preparation that improves male's sexual, it is characterized in that be by following raw materials by weight portion than the preparation of making:

Testis et penis callorhini 1～3, Penis et testis cervi 5～15, Cornu Cervi Pantotrichum 5～15, Testis Et penis Equi 5～15,

Penis et Testis Canis 45～55, Radix Ginseng 45～55, Fructus Lycii 45～55, Fructus Corni 45～55,

Cordyceps 15～25, Herba Epimedii 45～55, Radix Polygoni Multiflori 45～55, the Radix Astragali 45～55,

Radix Et Caulis Acanthopanacis Senticosi 45～55, Poria 45～55, Mel 45～55.

2, Chinese medicine preparation according to claim 1 is characterized in that optimum ratio is (by ratio of weight and the number of copies):

Testis et penis callorhini 2, Penis et testis cervi 10, Cornu Cervi Pantotrichum 10, Testis Et penis Equi 10, Penis et Testis Canis 50, Radix Ginseng 50,

Fructus Lycii 50, Fructus Corni 50, Cordyceps 20, Herba Epimedii 50, Radix Polygoni Multiflori 50,

The Radix Astragali 50, Radix Et Caulis Acanthopanacis Senticosi 50, Poria 50, Mel 50.

3,, it is characterized in that said medicament is a said dosage form on any pharmaceutics according to claim 1,2 described Chinese medicine preparation.