CN104435126B - Traditional Chinese medicine preparation for improving rheumatic arthralgia and resisting fatigue and preparation method thereof - Google Patents

Traditional Chinese medicine preparation for improving rheumatic arthralgia and resisting fatigue and preparation method thereof Download PDF

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CN104435126B
CN104435126B CN201410792493.7A CN201410792493A CN104435126B CN 104435126 B CN104435126 B CN 104435126B CN 201410792493 A CN201410792493 A CN 201410792493A CN 104435126 B CN104435126 B CN 104435126B
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chinese medicine
parts
rheumatic arthralgia
preparation
traditional chinese
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CN104435126A (en
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王祝年
董志超
王茂媛
羊青
晏小霞
王清隆
王建荣
高非
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Tropical Crops Genetic Resources Institute CATAS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486Millettia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/074Ganoderma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration

Abstract

The invention provides a traditional Chinese medicine preparation for improving rheumatic arthralgia and resisting fatigue and a preparation method thereof. According to the traditional Chinese medicine preparation, the alcohol extracts of a traditional Chinese medicine composition serve as active ingredients, the traditional Chinese medicine composition comprises the following components: 20-50 parts of beautiful millettia root, 0.5-5 parts of philippine flemingia root, 0.5-5 parts of radix fici simplicissimae, 0.1-2 parts of lucid ganoderma and 0.1-4 parts of schisandra chinensis, and the traditional Chinese medicine preparation is obtained by extracting the traditional Chinese medicine composition in the first aspect by using wine according to cold-maceration, hot dipping, percolation or reflux hot dipping. The traditional Chinese medicine preparation disclosed by the invention has good curative effects on symptoms such as cough of deficiency lung, deficiency of the kidney, spermatorrhea, leucorrhea, rheumatic arthralgia, waist and knee pain and fatigue and is small in toxic and side effects and safe to use.

Description

A kind of Chinese medicine preparation improving rheumatic arthralgia, resisting fatigue and preparation method thereof
Technical field
The present invention relates to and field of medicaments, specifically, the present invention relates to a kind of for bone and muscle strengthening, relaxing muscles and tendons and activating QI and blood in the collateral, change Kind rheumatic arthralgia, soreness of waist and knee joint, Chinese medicine preparation of resisting fatigue and preparation method thereof.
Background technology
Millettia Speciosa (Millettia speciosa Champ.) also known as beautiful millettia, are pulse family (Leguminosae) Millettia (Millettia Wight et Arn.) plant, medicine name Millettia Speciosa, also known as cattle energetically(《The SHENGCAO property of medicine is standby will》)、 Radix Millettiae Speciosae(《Luchuan book on Chinese herbal medicine》), slope Rhizoma Nelumbiniss(《Luchuan book on Chinese herbal medicine》), ground lotus root(《Nanning City's medicine will》), Caulis seu Radix Schisandrae Henryi, big Rhizoma Nelumbiniss(《Guangxi Medicinal plants register》).It is distributed in China Fujian, Hunan, Guangdong, Guangxi, Yunnan and Guizhou.Its root is used as medicine, and nature and flavor are sweet, trembles with fear.Tool There are qi-restoratives lung moistening, cough-relieving, strong muscle active.Millettia Speciosa medication is with a long history, early in《The SHENGCAO property of medicine is standby will》Record:" strong Muscles and bones, relieving heat toxin, manage internal injury, control traumatic injury, infusing drugs in wine nourishing kidney.”《Luchuan book on Chinese herbal medicine》Record:" clearing away lung-heat to relieve cough, refreshing and detoxicating.Control hemoptysis, Dysentery, epidemic febrile disease fever of the body is thirsty, dizzy.”《Guangdong Chinese herbal medicine》Record:" control cough due to deficiency of the lung, puerperal asthenia, limbs fatigue, carbuncle Skin ulcer.”).Among the people for treat cough due to deficiency of the lung, hemoptysis, breath with cough, the disease such as lumbar muscle strain, rheumatism paralysis, traumatic injury;Clinic is demonstrate,proved Real its has therapeutical effect to multiple chronic diseases, is mainly used in treating rheumatic arthritis, pulmonary tuberculosis, chronic bronchitiss, slow The property disease such as hepatitis, lumbar muscle strain(《National Chinese herbal medicine compilation》).Modern study shows, Millettia Speciosa root mainly contains saccharide, biology Alkali, flavones ingredient.Experiment mice B lymphocytic emiocytosis specific antibody and T lymphocyte generation interleukin-2 are had and exempts from Epidemic disease adjustment effect;Millettia Speciosa polysaccharide is one of main active that Millettia Speciosa adjusts immunologic function, and mouse T lymphocyte is increased Grow with dual regulation.Millettia Speciosa Aqueous extracts have multiple biological activities, are preferable immunostimulants, and to normally thin Born of the same parents do not have toxic and side effects, are used for antitumor, antiviral, anti-ageing drug research of waiting for a long time.
The very heavy group of property of medicine is sweet, tepor, puts down.Return lung, kidney, bladder warp, have expelling wind and removing dampness, and repercussive merit of removing toxic substances is imitated.Cure mainly wind Pain of dampness syndrome, extremity are aching and limp powerless, traumatic injury, can relaxing muscles and tendons and activating QI and blood in the collateral.Often and Millettia Speciosa compatibility, contribute to the relaxing muscles and tendons of monarch drug Millettia Speciosa The effect of active treatment rheumatic arthralgia.Pharmacological research shows, Radix Flemingiae Philippinensiss have analgesia, antiinflammatory, to peripheral nerve injury and brain group The protective effect knitted.
Ganoderma nature and flavor are sweet, put down;GUIXIN, lung, liver and kidney channel.The effect of beneficial essence, the kidney invigorating, wind-dispelling, cure mainly asthenia, cough, gas Breathe heavily, have a sleepless night, dyspepsia etc., also hepatoprotective, improve immunologic function, antibacterial etc. acts on.The kidney invigorating of Millettia Speciosa can not only be helped, dispel The work(of rheumatic arthralgia, moreover it is possible to reach raising immune function of human body, strengthens effect of resistance of human body.
Herba Fici Simplicissimae nature and flavor are sweet, tepor.There is the effect of invigorating the spleen for eliminating dampness, promoting the circulation of QI and reducing phlegm, relaxing muscles and tendons and activating QI and blood in the collateral.Cough for pulmonary tuberculosis Cough, chronic bronchitiss, rheumatic arthritis, lumbago and skelalgia, insufficiency of the spleen edema, night sweat after being ill, leucorrhea.Research finds its decoct, second The water extract of residue after alcohol extracting thing, alcohol reflux, all has substantially to the cough that mouse gavaging causes to ammonia spraying respectively Antitussive action.Test tubes also have preferable bacteriostasis to staphylococcus aureuses, alpha streptococcuss.
The acid of Fructus Schisandrae Chinensis nature and flavor, temperature;Return lung, kidney channel.Astringe the lung, nourishing kidney, promote the production of body fluid, receive the effect of antiperspirant, arresting seminal emission.Cure mainly the deficiency of the lung to breathe heavily Cough, xerostomia makees thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, protracted dysentery and diarrhea.Modern study shows, Fructus Schisandrae Chinensis contain abundant Organic acid, vitamin, flavonoid, phytosterol and the lignan having potent reactivation(Such as schisandrin, Fructus Schisandrae Chinensis B prime or Fructus Schisandrae Chinensis fat element), the energy strong liver of QI invigorating, enhancement cell are excluded the efficiency of waste, are supplied more oxygen, construction and use energy Amount, raising memory and property endurance.
At present although there being the report with Millettia Speciosa for principal agent compatibility other medical material, but there is not yet above-mentioned five kinds of Chinese medicine is common For bone and muscle strengthening, relaxing muscles and tendons and activating QI and blood in the collateral, the relevant report improving the aspects such as rheumatic arthralgia, soreness of waist and knee joint, resisting fatigue and research.
Content of the invention
It is an object of the present invention to provide a kind of Chinese medicine composition improving rheumatic arthralgia, resisting fatigue, can be used for strong Muscle bone strengthening, relaxing muscles and tendons and activating QI and blood in the collateral, improve rheumatic arthralgia, soreness of waist and knee joint, resisting fatigue etc..It is a further object to provide adopting institute The ethanol extract stating Chinese medicine composition is the Chinese medicine preparation of active substance.It is also another object of the present invention to provide described Chinese medicine preparation Preparation method.
The first aspect of the invention is to provide a kind of Chinese medicine composition improving rheumatic arthralgia, resisting fatigue, according to weight Number meter, its composition includes 20 ~ 50 parts of Millettia Speciosa, 0.5 ~ 5 part of Radix Flemingiae Philippinensiss, 0.5 ~ 5 part of Herba Fici Simplicissimae, 0.1 ~ 2 part of Ganoderma and five 0.1 ~ 4 part of taste.
Preferably, in parts by weight, the composition of described Chinese medicine composition includes 30 ~ 40 parts of Millettia Speciosa, Radix Flemingiae Philippinensiss 1 ~ 4 Part, 1 ~ 4 part of Herba Fici Simplicissimae, 0.3 ~ 1 part of Ganoderma and 0.5 ~ 2 part of Fructus Schisandrae Chinensis.
Preferably, in parts by weight, the composition of described Chinese medicine composition includes 34.5 parts of Millettia Speciosa, 2 parts of Radix Flemingiae Philippinensiss, 2 parts of Herba Fici Simplicissimae, 0.5 part of Ganoderma and 1 part of Fructus Schisandrae Chinensis.
The second aspect of the invention is to provide a kind of Chinese medicine preparation improving rheumatic arthralgia, resisting fatigue, described Chinese medicine system The ethanol extract of Chinese medicine composition described in present invention one side for the active component of agent.
Described Chinese medicine preparation can be prepared into any oral drugs, such as powder, medicated wine, pill, tablet etc..
It should be appreciated that described Chinese medicine preparation also includes pharmaceutically acceptable adjuvant, for example correctivess, antioxidant, Filler, stabilizer etc..
3rd aspect of invention is the Chinese medicine improving rheumatic arthralgia, resisting fatigue providing described in second aspect of the present invention The preparation method of preparation, described to present invention one side according to cold-maceration, hot dipping, percolation or backflow hot dipping with wine Chinese medicine composition carry out extraction and obtain.
Wherein, cold-maceration refers to medical material and appropriate wine are co-located in hermetic container, impregnates at room temperature, periodic agitation, General dipping more than 30 days.Take supernatant, squeeze medicinal residues, pressed liquor is merged with supernatant, stirs, standing, filtration, take filter Liquid obtains final product.
Wherein, hot dipping refers to medical material and appropriate wine are placed in container with lid, water-bath or after being steam heated to boiling immediately Stop heating, be then poured in another container with lid, airtight, impregnate one to several months, periodic agitation at room temperature, then draw supernatant Liquid, squeezes medicinal residues, supernatant is merged with pressed liquor, standing, and filtration takes filtrate to obtain final product.
Wherein, percolation refers to take the medical material of suitable pulverizing, by percolation operation, collects percolate, stands, filtration, that is, ?.
Wherein, backflow hot dipping refers to medical material is immersed in wine, after being heated to reflux, extracting liq, and obtain final product.
Wherein cold-maceration, the process time of hot dipping, percolation or backflow hot dipping can be determined according to actual needs And adjustment.
Product being obtained using said method can add the correctivess such as sugar or honey to be rectified directly as medicated wine as needed Taste.As needed said method can also be obtained product to concentrate, powder is made in drying, or pill, or film-making etc., make Various oral formulations.
Wherein, described wine is to adopt any edible ethanol, such as rice wine, yellow wine, Chinese liquor etc..
Preferably, in described wine, the content of ethanol is 15 ~ 70%(v/v).
In prescription, Millettia Speciosa is monarch drug, have that qi-restoratives lung moistening, cough-relieving, strong muscle be active, enhancing immunity the effect of, very heavy Pull out the effect of relaxing muscles and tendons and activating QI and blood in the collateral of Millettia Speciosa can be promoted to treat rheumatic arthralgia, Ganoderma not only helps the kidney invigorating of Millettia Speciosa, dispels wind The work(of pain of dampness syndrome moreover it is possible to reach raising immune function of human body, strengthen resistance of human body effect, then compatibility have invigorating the spleen for eliminating dampness, The effect of promoting the circulation of QI and reducing phlegm, relaxing muscles and tendons and activating QI and blood in the collateral Herba Fici Simplicissimae, and Fructus Schisandrae Chinensis the effects such as there is nourishing kidney, promote the production of body fluid, have good strong Muscle bone strengthening, relaxing muscles and tendons and activating QI and blood in the collateral and antifatigue effect, to cough due to deficiency of the lung, kidney deficiency, seminal emission, leucorrhea, rheumatic arthralgia, soreness of waist and knee joint, tired The diseases such as labor have good curative effect.Meanwhile, prescription Chinese crude drug of the present invention passes through compatibility, can adjust inherent internal organs function, increases Strong body body constitution, improves immunity of organisms, reaches the purpose for the treatment of both the principal and the secondary aspects of a disease at the same time.Additionally, medical material all comes used in prescription of the present invention Come from natural plants, effect relaxes persistently, and toxic and side effects are little, and using safety, relapse rate is low.
Specific embodiment
With reference to specific embodiment, the present invention is described further, to more fully understand the present invention.
In order to preferably compare the property of medicine of each embodiment, each embodiment adopts identical preparation method cold-maceration, and prepares Process conditions are identical it should be appreciated that those skilled in the art can carry out suitable adjustment to preparation process condition, or Other preparation methoies, such as hot dipping, percolation or backflow hot dipping etc. can also be adopted.
Embodiment 1
By 34.5 grams of Millettia Speciosa, 2 grams of Radix Flemingiae Philippinensiss, 2g Herba Fici Simplicissimae and the section of 0.5g Ganoderma medical material, add 1g Fructus Schisandrae Chinensis, plus Enter yellow wine(Purchased from Guyuelongshan Shaoxing Wine Co Ltd, Zhejiang)To 1L, sealing preserve 1 year.Then sterilize, canned to 100 In individual bottle for oral use, both.
Embodiment 2
By 30 grams of Millettia Speciosa, 4 grams of Radix Flemingiae Philippinensiss, 1g Herba Fici Simplicissimae and the section of 0.3g Ganoderma medical material, add 2g Fructus Schisandrae Chinensis, add Yellow wine is to 1L, sealing preserve 1 year.Add Mel to carry out taste masking according to the ratio that 20 grams of medicated wine add 1 gram of Mel, then go out Bacterium, in canned to 100 bottles for oral use, both.
Embodiment 3
By 40 grams of Millettia Speciosa, 1 gram of Radix Flemingiae Philippinensis, 4g Herba Fici Simplicissimae and the section of 1g Ganoderma medical material, add 0.5g Fructus Schisandrae Chinensis, add Yellow wine is to 1L, sealing preserve 1 year.Add Mel to carry out taste masking according to the ratio that 20 grams of medicated wine add 1 gram of Mel, then go out Bacterium, in canned to 100 bottles for oral use, both.
Embodiment 4
By 20 grams of Millettia Speciosa, 5 grams of Radix Flemingiae Philippinensiss, 5g Herba Fici Simplicissimae and the section of 0.1g Ganoderma medical material, add 4g Fructus Schisandrae Chinensis, add Yellow wine is to 1L, sealing preserve 1 year.Add Mel to carry out taste masking according to the ratio that 20 grams of medicated wine add 1 gram of Mel, then go out Bacterium, in canned to 100 bottles for oral use, both.
Embodiment 5
By 50 grams of Millettia Speciosa, 0.5 gram of Radix Flemingiae Philippinensis, 0.5g Herba Fici Simplicissimae and the section of 2g Ganoderma medical material, add 0.1g Fructus Schisandrae Chinensis, Add yellow wine to 1L, sealing preserve 1 year.Mel is added to carry out taste masking according to the ratio that 20 grams of medicated wine add 1 gram of Mel, then Sterilizing, in canned to 100 bottles for oral use, both.
Comparative example 1
Prepare medicated wine according to the same manner as in Example 1, difference is in medicated wine to be added without the five fingers hair and the five tastes Son.
Comparative example 2
Prepare medicated wine according to the same manner as in Example 1, difference is in medicated wine to be added without Radix Flemingiae Philippinensiss.
Comparative example 3
Prepare medicated wine according to the same manner as in Example 1, difference is in medicated wine to be added without Ganoderma.
Improve rheumatic arthralgia test
The diagnostic criteria of rheumatic arthralgia according to《Chinese medical disease diagnosis and treatment standard》The diagnosis basis of rheumatism numbness are judging:1st, with four Limb large joint is walked and is altered based on pain, with soreness of waist and knee joint, numbness, joint joint stuffiness, has the symptoms such as aversion to cold, heating more;2nd, before disease There is pharyngalgia tonsillitis history more, or paddle and drench with rain, occupy wetland history long;3rd, some patientss can have low grade fever, extremity erythema iriss, or nodositas Erythema.Often can Cardiac Involvemant;4th, erythrocyte sedimentation rate speeds, and antistreptolysin " 0 " is more than 500 units.
Case:Choose the patient 400 meeting above-mentioned diagnostic criteria, the wherein each half of men and women, 40 years old mean age.Treatment Method:Above-mentioned patient is divided into 8 groups, every group of 50 patients, the situation no difference of science of statistics of the patient between each group.Apply respectively With the medicated wine in embodiment 1 ~ 5 and comparative example 1 ~ 3, daily 3 times, 30 grams every time.It is within continuous 6 weeks a course for the treatment of.
Efficacy assessment standard according to《The guideline of clinical investigations for the treatment of by Chinese herbs arthromyodynia》, reference《Arthromyodynia opinion is made a study of subjects》、《Class Rheumatic arthritis》Relevant content is drafted, and is divided into healing, improvement, does not heal.On the traditional Chinese medical science, medicated wine is cured and the in the case of of taking a turn for the better is also referred to as There is the effect of " bone and muscle strengthening, relaxing muscles and tendons and activating QI and blood in the collateral " for medicated wine.
Cure:Symptom disappears, and joint motion is normal, and lab testing is normal;
Take a turn for the better:Symptom is clearly better, and lab testing has improvement;
Do not heal:Symptom and lab testing are no progressive.
Result of the test see table 1.
Table 1
As shown in Table 1, the medicated wine of the present invention containing Millettia Speciosa, Radix Flemingiae Philippinensiss, Herba Fici Simplicissimae, Ganoderma and Fructus Schisandrae Chinensis compares ratio The effect of example will be got well, and illustrates that the medicated wine of the present invention passes through compatibility, it improves the effect of rheumatic arthralgia and is substantially better than 3 contrasts Example.Additionally, regular return visit is carried out to the patient after treatment, in 1 year, have no recidivist.
Anti-fatigue test
Experiment content:The raising of exercise tolerance is that anti-fatigue ability is strengthened the most directly showing, and the length of swimming time can To reflect the degree of fatigue of animal movement.Born a heavy burden by mice(The sheet lead of body weight 5%)Swimming, by with matched group swimming time Contrast, determines the resisting fatigue effect of medicine.
Experimental technique:From bull kunming mice, body weight 18-22g.If a blank control group and several tested material Group, according to the human body every kg body weight daily intaking amount recommended, being converted into the every consumption per day of mice is 0.2ml, directly carries out gavage.Cause It is drinks for administration, according to experiment needs, after administration 30min, the sheet lead of rat-tail root load 5% body weight, mice is placed in swimming Case went swimming.The depth of water is no less than 30cm, 25 ± 0.5 DEG C of water temperature, and mice starts to the death time of swimming record from swimming.To implement Medicated wine in example 1 ~ 5 and comparative example 1 ~ 3 is tested, and obtains result as shown in table 2.
Table 2
As shown in Table 2, the medicated wine of the present invention passes through compatibility, has good resisting fatigue effect, and resisting fatigue effect is obvious Better than 3 comparative examples.
Above the specific embodiment of the present invention is described in detail, but it has been intended only as example, the present invention has not limited It is formed on particular embodiments described above.To those skilled in the art, any equivalent modifications that the present invention is carried out and Substitute also all among scope of the invention.Therefore, the impartial conversion made without departing from the spirit and scope of the invention and Modification, all should cover within the scope of the invention.

Claims (7)

1. a kind of Chinese medicine composition improving rheumatic arthralgia, resisting fatigue is it is characterised in that in parts by weight, its composition bag Include 20 ~ 50 parts of Millettia Speciosa, 0.5 ~ 5 part of Radix Flemingiae Philippinensiss, 0.5 ~ 5 part of Herba Fici Simplicissimae, 0.1 ~ 2 part of Ganoderma and 0.1 ~ 4 part of Fructus Schisandrae Chinensis.
2. the Chinese medicine composition improving rheumatic arthralgia, resisting fatigue according to claim 1 is it is characterised in that according to weight Number meter, its composition includes 30 ~ 40 parts of Millettia Speciosa, 1 ~ 4 part of Radix Flemingiae Philippinensiss, 1 ~ 4 part of Herba Fici Simplicissimae, 0.3 ~ 1 part of Ganoderma and Fructus Schisandrae Chinensis 0.5 ~ 2 part.
3. the Chinese medicine composition improving rheumatic arthralgia, resisting fatigue according to claim 1 is it is characterised in that according to weight Number meter, its composition includes 34.5 parts of Millettia Speciosa, 2 parts of Radix Flemingiae Philippinensiss, 2 parts of Herba Fici Simplicissimae, 0.5 part of Ganoderma and 1 part of Fructus Schisandrae Chinensis.
4. a kind of Chinese medicine preparation improving rheumatic arthralgia, resisting fatigue is it is characterised in that the active component of described Chinese medicine preparation is power Profit requires the ethanol extract of the Chinese medicine composition described in any one in 1 ~ 3.
5. the Chinese medicine preparation improving rheumatic arthralgia, resisting fatigue according to claim 4 is it is characterised in that described Chinese medicine system The dosage form of agent is medicated wine, powder, pill or tablet.
6. a kind of preparation method of the Chinese medicine preparation improving rheumatic arthralgia, resisting fatigue as claimed in claim 4, its feature exists In with wine according to cold-maceration, hot dipping, percolation or backflow hot dipping to the Chinese medicine described in any one in claim 1 ~ 3 Compositionss carry out extraction and obtain.
7. preparation method according to claim 6 is it is characterised in that be obtained powder by extracting the product concentrate drying obtaining Agent, or pill, or tabletting.
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