CN1321652C - Chinese traditional medicine composition for resisting Helicobacter pylori - Google Patents

Chinese traditional medicine composition for resisting Helicobacter pylori Download PDF

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Publication number
CN1321652C
CN1321652C CNB2004100610723A CN200410061072A CN1321652C CN 1321652 C CN1321652 C CN 1321652C CN B2004100610723 A CNB2004100610723 A CN B2004100610723A CN 200410061072 A CN200410061072 A CN 200410061072A CN 1321652 C CN1321652 C CN 1321652C
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helicobacter pylori
present
medicine composition
weight
ingredients
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Expired - Fee Related
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CNB2004100610723A
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Chinese (zh)
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CN1634320A (en
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王崇文
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Abstract

The present invention relates to a traditional Chinese medicine composition for resisting helicobacter pylori, which is characterized in that the active ingredients of the present invention are composed of water extracts made from the raw materials of the following proportion by weight: 10 to 20g of dandelion, 6 to 8g of rhizoma coptidis, 8 to 12g of lightyellow sophora root and 2 to 5g of clove. The making method comprises the steps that the raw materials are pulverized, added with distilled water according to the weight-volume ratio of 1:5 to be dococted for one hour and filtered so as to remove the dregs of a decoction; then the clear solution is concentrated, dried and made into powder. The present invention has the functions of reducing fever and diminishing inflammation; all the ingredients of the prescription of the present invention have the function of killing helicobacter pylori and have synergistic effect; by using all the ingredients simultaneously, therapeutic effect of resisting helicobacter pylori can be enhanced, and the chronic disease inflammation of the gastric mucosa can be relieved.

Description

Chinese medicine composition of a kind of anti-helicobacter pylori and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition of anti-helicobacter pylori.
Background technology
Since nineteen eighty-three Warren and Marshall isolated helicobacter pylori (Helicobacterpylori, abbreviation Hp), the pathogenic effects of Hp in gastroduodenal diseases such as chronic gastritis, peptic ulcer, gastric cancer obtained generally acknowledging of people.Hp infection rate height in the population of China, gastroduodenal disease is modal internal disease, the serious harm people's health.Thereby it is diseases related for prevention Hp effectively to eradicate Hp, and particularly gastric cancer has a crucial meaning.Though it is multiple that the Western medicine of present anti-Hp has, the Therapeutic Method of eradicating Hp also has much, but it is how not ideal enough, have many problems, curative effect is standard three (proton pump inhibitor adds amoxicillin and metronidazole) and new three (proton pump inhibitor adds clarithromycin and amoxicillin or metronidazole) preferably, and the Hp eradication rate can reach 85-90%, but the former side effect is bigger, patient's compliance is relatively poor, and the latter costs an arm and a leg, and the two all has Hp to metronidazole drug resistance problem.Therefore explore, efficient, inexpensive, toxic and side effects is low, resistant rate is low, simple and easy to do and anti-Hp therapy that patient's compliance is good, is the emphasis and the focus of current Hp clinical research.Traditional traditional Chinese medical science of China has rich experiences to the treatment of infection and chronic gastritis, and Chinese herbal medicine resource is abundant, and it is inexpensive, and toxic and side effects is little.
Summary of the invention
Purpose of the present invention just provides a kind of Chinese medicine composition of anti-helicobacter pylori.
The present invention is achieved like this, and the water extract that its active ingredient is made by following materials of weight proportions is formed: Herba Taraxaci 10-20g, Rhizoma Coptidis 6-8g, Radix Sophorae Flavescentis 8-12g, Flos Caryophylli 2-5g.Its preparation method is: above materials of weight proportions is pulverized, decocted 1 hour by 1: 5 (W/V) adding distil water, filter cleaner, clear liquid concentrate, oven dry, and pulverize is made capsule.
The present invention has dephlogisticating action, and various compositions all have killing action to helicobacter pylori in the prescription, and they have synergism each other, uses simultaneously and not only can improve the curative effect of anti-helicobacter pylori, and can alleviate the chronic disease inflammation of gastric mucosa.
The specific embodiment
Embodiment one takes by weighing Herba Taraxaci 15g, Rhizoma Coptidis 5g, Radix Sophorae Flavescentis 10g, Flos Caryophylli 3g, and with above raw material pulverizing, adding distil water 165ml decocted 1 hour, and filter and remove residue concentrates clear liquid, dry, and pulverize is made capsule.
Embodiment two takes by weighing Herba Taraxaci 10g, Rhizoma Coptidis 6g, Radix Sophorae Flavescentis 8g, Flos Caryophylli 2g, and above materials of weight proportions is pulverized, and adding distil water 130ml decocted 1 hour, and filter and remove residue concentrates clear liquid, dry, and pulverize is made capsule.
Embodiment three takes by weighing Herba Taraxaci 20g, Rhizoma Coptidis 8g, Radix Sophorae Flavescentis 12g, Flos Caryophylli 5g, and with above raw material pulverizing, adding distil water 225ml decocted 1 hour, and filter and remove residue concentrates clear liquid, dry, and pulverize is made capsule.
Clinical research:
1, object of study: the outpatient service and inpatient 196 examples of the Hp positive chronic gastritis of making a definite diagnosis through gastroscope, histological examination, the stomach of active stage, duodenal ulcer, male 143 examples, women 56 examples, mean age 41-52 year.
2, exclusion standard: the 1. patient of cardiopulmonary, liver system serious disease; 2. postoperative and mechanical obstruction patient; 3. use antibiotic in 2 weeks, press down other anti-Hp Drug therapy patients such as sour medicine and bismuth preparation.
3, clinical observation result:
Example number N Recovery from illness N% Produce effects N% Effective N% Invalid N% Cure-remarkable-effectiveness rate % Total effective rate %
196 114 58.2 48 24.5 22 11.2 12 6.1 82.7 93.9

Claims (2)

1, a kind of Chinese medicine composition of anti-helicobacter pylori is characterized in that the water extract that its active ingredient is made by following materials of weight proportions forms: Herba Taraxaci 10-20g Rhizoma Coptidis 6-8g, Radix Sophorae Flavescentis 8-12g, Flos Caryophylli 2-5g.
2, the preparation method of the Chinese medicine composition of the described anti-helicobacter pylori of a kind of claim 1 is characterized in that: above materials of weight proportions is pulverized, decocted 1 hour by weight 1: 5 adding distil water, filter cleaner, clear liquid concentrates, oven dry, and pulverize is made capsule.
CNB2004100610723A 2004-11-05 2004-11-05 Chinese traditional medicine composition for resisting Helicobacter pylori Expired - Fee Related CN1321652C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNB2004100610723A CN1321652C (en) 2004-11-05 2004-11-05 Chinese traditional medicine composition for resisting Helicobacter pylori

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB2004100610723A CN1321652C (en) 2004-11-05 2004-11-05 Chinese traditional medicine composition for resisting Helicobacter pylori

Publications (2)

Publication Number Publication Date
CN1634320A CN1634320A (en) 2005-07-06
CN1321652C true CN1321652C (en) 2007-06-20

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CNB2004100610723A Expired - Fee Related CN1321652C (en) 2004-11-05 2004-11-05 Chinese traditional medicine composition for resisting Helicobacter pylori

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Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103070923B (en) * 2013-01-23 2014-07-16 广州铁路职业技术学院 Medicated wine for treating stomach disease and preparation method thereof
CN104784408A (en) * 2015-05-02 2015-07-22 淄博齐鼎立专利信息咨询有限公司 Application of traditional Chinese medicine composition to preparation of anti-helicobacter pylori medicines
CN113080450A (en) * 2021-04-13 2021-07-09 花开星辰化妆品(浙江)有限公司 Health food for inhibiting and killing helicobacter pylori and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
胃泰胶囊治疗幽门螺杆菌相关性胃十二指肠疾病疗效分析 王崇文等,现代诊断与治疗,第11卷第3期 2000 *

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